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The map label for this gene is adrA [H]

Identifier: 186476908

GI number: 186476908

Start: 2418894

End: 2420573

Strand: Direct

Name: adrA [H]

Synonym: Bphy_2157

Alternate gene names: 186476908

Gene position: 2418894-2420573 (Clockwise)

Preceding gene: 186476905

Following gene: 186476909

Centisome position: 69.52

GC content: 66.67

Gene sequence:

>1680_bases
ATGAAAAGGACAACCTTGCGCCAGGCATTGGGACCGGCCAGTTTCGTACTGGTCGTGCTCGCATGCTGGTTCGCCTCCGG
CCTGGTCGCGGACCGGATGGTACAGCAAGAACTGGATACCGCACTGCGCCAGCAGCGGCAAATGTCCGCCTCGATCGTCT
ACAACATGGCCGAAGTGATCGCGAGCGACCTGGCAATGTCCCGGGCCATACCCGCGACGATGGCCGAGCTCGGTGTGATT
CAACAGGCTCTGACGCATTCGCAGAATTATGCCGCTTCAGGCGTGGACCTGGAACCCGCGCACCGCGAGGAGCTGTTGAA
ATCGCCTGAACTGGCGGGCATCAACGGCTTTTTGCGTGACGCCCAAGGCTTCTCGGGACTCGACATCATCTGGCTCGTCA
ACGCCAACGGCCTGTGCGTCGCCGCGAGCAACGCGCAGAACGCGCATTCGTTCGTCGGTATCGACATGCGCTCGCGCAGC
TATCTGACCAACGCGCTGCTTGGCGCCTTTGGCGAGGCGTACGGCGTCGGCCGCATGAGCGGCGAGCCCGGCATCTTCAT
CTCGGCGCCCGTGTACGACGACGGGCTGCTGGTCGGCGCGATCGTCGCCAAGGTCGGCATCGCGCGACTGCGCCACTGGG
TCGCCCACGCGGGCACCTTCGTCACCGACGACAACGGCGTGATCATCATGGCGCACAATGCCGCGCTCGAAGGCCAGGCG
ATGCCAAACTCGCGCGTCACGCAGATGAAACCGGCCGAGCGCATGAGCACGTATCATCGCGTGCAGTTTCCCGCCGTGCA
GATTCAGCCCGTCAAGAGCCAGGTGCGCGGCGATGCGCCGTGGGTGCCCGCCGACATCGCCGACCAGCTGTACGACATGC
CGAGCCAGCCGATCCCGACGCTCTACCAGTCGCGCAGCGGACTGAACTCCGGCCTGTCGGCGCATCTCGTCGATCCGCTC
GTCGCCTGGCCCGAACTGATGCGCAATCACAAGCGCGATCATCTGCTCGTCTTCCTGACGCTCGCGGGCACGGTGGCGCT
CGCGTGGGTGATCACCGTGTCGTATCTGCGCGAGCGGCGTCATCACCGCGCGACCCGCGTGCTCGCGGAACAGCTGCAGT
CGGCGAACACGCTGCTGTCGGCGGAAGCCCGCCACGATGCGCTGACGGGCGCGCTGTCGCGCCGCTACTTCCTCGACCTG
CTGCGCCATGAGATCGAGCGGGCGCGCGCGACGGGCGAACCGCTATGCATGGCGATCGCCGACCTCGATCATTTCAAGCA
GATCAATGACCGCTTCGGGCACGCGGCGGGCGACCGGGCGCTCGAACATTTCGTCGACACGTGCCGCACCGCGCTGCGCG
GCAGCGACGCGATCGGCCGGCTGGGCGGCGAAGAGTTCGGCATCCTGCTGCCGGACACGCCGCTCGGCACCGGCCTCGAA
GTGGTCGAACGCCTGCGTGTGCGGCTGAAGACGATGCCGTCGACGAAGCTGCCGCAATCGGTGGGCTTGAGCGTAAGTAT
CGGCATCACGGAACTGTCGGCGGAGGACTTGCCCGAGCGCATCATCAGCCGCGCCGATCAGGCGCTCTACGCCGCGAAAC
AGGGTGGCCGCGACCGCAGCGAAGCCGTGCCGCCCGACGACACCGCGCCACCCGCGCGGGCCCCCGTCAACGCGTGGTAA

Upstream 100 bases:

>100_bases
CCGTGCGGTGCACGGGGGGAATCGACAGGAGCGGCCCAGCGCCAGCGCGTTGCAACGAGAGACGTTGTTGCATGAATCAG
TCAGACGGATCAGAGGGTCG

Downstream 100 bases:

>100_bases
CGGGCAGCTTCAGTCGAACCCGATCGCCCTGGCACGATGCGGGGCGCATTCCATATCGAAGCCGCCGGGCAAGCGGAGCG
CAAGCAGGTATGATCGACTT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MKRTTLRQALGPASFVLVVLACWFASGLVADRMVQQELDTALRQQRQMSASIVYNMAEVIASDLAMSRAIPATMAELGVI
QQALTHSQNYAASGVDLEPAHREELLKSPELAGINGFLRDAQGFSGLDIIWLVNANGLCVAASNAQNAHSFVGIDMRSRS
YLTNALLGAFGEAYGVGRMSGEPGIFISAPVYDDGLLVGAIVAKVGIARLRHWVAHAGTFVTDDNGVIIMAHNAALEGQA
MPNSRVTQMKPAERMSTYHRVQFPAVQIQPVKSQVRGDAPWVPADIADQLYDMPSQPIPTLYQSRSGLNSGLSAHLVDPL
VAWPELMRNHKRDHLLVFLTLAGTVALAWVITVSYLRERRHHRATRVLAEQLQSANTLLSAEARHDALTGALSRRYFLDL
LRHEIERARATGEPLCMAIADLDHFKQINDRFGHAAGDRALEHFVDTCRTALRGSDAIGRLGGEEFGILLPDTPLGTGLE
VVERLRVRLKTMPSTKLPQSVGLSVSIGITELSAEDLPERIISRADQALYAAKQGGRDRSEAVPPDDTAPPARAPVNAW

Sequences:

>Translated_559_residues
MKRTTLRQALGPASFVLVVLACWFASGLVADRMVQQELDTALRQQRQMSASIVYNMAEVIASDLAMSRAIPATMAELGVI
QQALTHSQNYAASGVDLEPAHREELLKSPELAGINGFLRDAQGFSGLDIIWLVNANGLCVAASNAQNAHSFVGIDMRSRS
YLTNALLGAFGEAYGVGRMSGEPGIFISAPVYDDGLLVGAIVAKVGIARLRHWVAHAGTFVTDDNGVIIMAHNAALEGQA
MPNSRVTQMKPAERMSTYHRVQFPAVQIQPVKSQVRGDAPWVPADIADQLYDMPSQPIPTLYQSRSGLNSGLSAHLVDPL
VAWPELMRNHKRDHLLVFLTLAGTVALAWVITVSYLRERRHHRATRVLAEQLQSANTLLSAEARHDALTGALSRRYFLDL
LRHEIERARATGEPLCMAIADLDHFKQINDRFGHAAGDRALEHFVDTCRTALRGSDAIGRLGGEEFGILLPDTPLGTGLE
VVERLRVRLKTMPSTKLPQSVGLSVSIGITELSAEDLPERIISRADQALYAAKQGGRDRSEAVPPDDTAPPARAPVNAW
>Mature_559_residues
MKRTTLRQALGPASFVLVVLACWFASGLVADRMVQQELDTALRQQRQMSASIVYNMAEVIASDLAMSRAIPATMAELGVI
QQALTHSQNYAASGVDLEPAHREELLKSPELAGINGFLRDAQGFSGLDIIWLVNANGLCVAASNAQNAHSFVGIDMRSRS
YLTNALLGAFGEAYGVGRMSGEPGIFISAPVYDDGLLVGAIVAKVGIARLRHWVAHAGTFVTDDNGVIIMAHNAALEGQA
MPNSRVTQMKPAERMSTYHRVQFPAVQIQPVKSQVRGDAPWVPADIADQLYDMPSQPIPTLYQSRSGLNSGLSAHLVDPL
VAWPELMRNHKRDHLLVFLTLAGTVALAWVITVSYLRERRHHRATRVLAEQLQSANTLLSAEARHDALTGALSRRYFLDL
LRHEIERARATGEPLCMAIADLDHFKQINDRFGHAAGDRALEHFVDTCRTALRGSDAIGRLGGEEFGILLPDTPLGTGLE
VVERLRVRLKTMPSTKLPQSVGLSVSIGITELSAEDLPERIISRADQALYAAKQGGRDRSEAVPPDDTAPPARAPVNAW

Specific function: Unknown

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=35.632183908046, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=36.0248447204969, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=40.1162790697674, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693134, Length=169, Percent_Identity=38.4615384615385, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=37.2093023255814, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788381, Length=172, Percent_Identity=34.8837209302326, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=32.9268292682927, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081974, Length=208, Percent_Identity=28.8461538461538, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=29.5180722891566, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=217, Percent_Identity=30.8755760368664, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=29.0909090909091, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 60792; Mature: 60792

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTTLRQALGPASFVLVVLACWFASGLVADRMVQQELDTALRQQRQMSASIVYNMAEVI
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDLAMSRAIPATMAELGVIQQALTHSQNYAASGVDLEPAHREELLKSPELAGINGFLRD
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
AQGFSGLDIIWLVNANGLCVAASNAQNAHSFVGIDMRSRSYLTNALLGAFGEAYGVGRMS
CCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
GEPGIFISAPVYDDGLLVGAIVAKVGIARLRHWVAHAGTFVTDDNGVIIMAHNAALEGQA
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCC
MPNSRVTQMKPAERMSTYHRVQFPAVQIQPVKSQVRGDAPWVPADIADQLYDMPSQPIPT
CCCCCCCCCCCHHHHHHHHHEECCCEEEECHHHHHCCCCCCCCHHHHHHHHCCCCCCCCH
LYQSRSGLNSGLSAHLVDPLVAWPELMRNHKRDHLLVFLTLAGTVALAWVITVSYLRERR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HHRATRVLAEQLQSANTLLSAEARHDALTGALSRRYFLDLLRHEIERARATGEPLCMAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
DLDHFKQINDRFGHAAGDRALEHFVDTCRTALRGSDAIGRLGGEEFGILLPDTPLGTGLE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCHHH
VVERLRVRLKTMPSTKLPQSVGLSVSIGITELSAEDLPERIISRADQALYAAKQGGRDRS
HHHHHHHHHHCCCCCCCCHHHCCEEEECEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EAVPPDDTAPPARAPVNAW
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRTTLRQALGPASFVLVVLACWFASGLVADRMVQQELDTALRQQRQMSASIVYNMAEVI
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDLAMSRAIPATMAELGVIQQALTHSQNYAASGVDLEPAHREELLKSPELAGINGFLRD
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
AQGFSGLDIIWLVNANGLCVAASNAQNAHSFVGIDMRSRSYLTNALLGAFGEAYGVGRMS
CCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCC
GEPGIFISAPVYDDGLLVGAIVAKVGIARLRHWVAHAGTFVTDDNGVIIMAHNAALEGQA
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCC
MPNSRVTQMKPAERMSTYHRVQFPAVQIQPVKSQVRGDAPWVPADIADQLYDMPSQPIPT
CCCCCCCCCCCHHHHHHHHHEECCCEEEECHHHHHCCCCCCCCHHHHHHHHCCCCCCCCH
LYQSRSGLNSGLSAHLVDPLVAWPELMRNHKRDHLLVFLTLAGTVALAWVITVSYLRERR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HHRATRVLAEQLQSANTLLSAEARHDALTGALSRRYFLDLLRHEIERARATGEPLCMAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
DLDHFKQINDRFGHAAGDRALEHFVDTCRTALRGSDAIGRLGGEEFGILLPDTPLGTGLE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCHHH
VVERLRVRLKTMPSTKLPQSVGLSVSIGITELSAEDLPERIISRADQALYAAKQGGRDRS
HHHHHHHHHHCCCCCCCCHHHCCEEEECEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EAVPPDDTAPPARAPVNAW
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]