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The map label for this gene is yciR [C]

Identifier: 186476873

GI number: 186476873

Start: 2379057

End: 2381432

Strand: Direct

Name: yciR [C]

Synonym: Bphy_2120

Alternate gene names: 186476873

Gene position: 2379057-2381432 (Clockwise)

Preceding gene: 186476872

Following gene: 186476874

Centisome position: 68.38

GC content: 62.75

Gene sequence:

>2376_bases
ATGAATCAGTTCCGCCTCTCTTCCGCGCGCGACGTCAGGCACCGCCTCGATCCGGCGGGAACGCGCCGGCGCGCGCTGCT
CGCGATTCCCGCGCTCGGCGTGCTGGTGCTCGTGCTGCTTTGGACGGTGATCTTCGCGCGGCTCTCGGTTGAAAAAGACA
CGACGTATCGCGAGGCGATGGCCTCGGCGGCCATTTTGTCCGCGGCACTCGAACAGCACACGGTGAAGGCGATTCACCAG
GTCGACCAGATCACGCGCTTCGTCAAATTCGAGTTCGAGAAAACGCCGGGCCATTTCGATCTCGCGAGCACGGTCGAAAA
AGGCGTCGTGCAAAGCGAGACGCTCGTCCAGGTGTCGCTGATCGACGAGCACGGCAAGCTGATCGCGAACACGGCGGAGG
CAAATCCGAAGCCCATCGACCTGTCCGATCGCGAGCACTTCAAGGTGCACGAGCACGAGAACGACGACCAGCTCTTCATC
AGCAAGCCCGTGCTCGGCCGAGTGTCCGGCCACTGGACTTTGCAGATGACGCGCCGACTGAATCATCCCGACGGTTCGTT
CGCGGGCGTCGTGGTCGTATCGGAAGACCCGAGCTATTTCACCAGCGACTTCTATAACAACGCGGCCATCGGCCGCGACG
GCGTGATCGCCGTGATCTCGGATAGCGGCGCCGTGCTCGCGCGCCGTACTGGCAACTCCGATCACACCCAGGGCGTATTC
ACGGCGACGGGTGTCTATCCCACTTCGGAGCACGTGTCGGGCACCTATGTGGATTCGATCGACAACGTGACGCGCATCGT
GTCGTACCGGCATATCGACGGCTATCCGCTCGGCGTGCTCGTCGGCCTGTCGCAGGCCGAAGAATTCGCGGACTACAACC
ACACCCGCAACGTCTATCTGCTGATGGCGAGCTTTATCTCGCTCGCGATGCTCGGTTTCTTCGCCGTCGCCACCGGGCTG
ATCGGCAAGCTGCTCGGACGCGAGCGCGAGATGACGCATCTCGTCGAATTCGATCTGCTCACGGGGTTGCGCAACCGCTA
CTCGACCTTGCAGAGTCTGCGTCACGAGGTAGGACAACCGGTGAACGTCGGGCATCTCGCGATCCTCTTCATCGACCTCG
ACAACTTCAAGACCGTCAACGACACGCTCGGCCATAACGCCGGCGACATCGTGCTGCAAATGACGGCCTCGCGTCTCGCG
GATGCAGTCGCCGACGCAGGCGCGCTGTCGCGCATCGGTGGCGACGAGTTCGTCGTCGTGATCAAGGGCGACGACGTCGA
GAAGCGCGCGGTGACGCTCGCGGAAGCGATCATCGACGTATTCGCAAAGCCGTTCGAAGTGCGCGGCAGTTCGTTCGTAC
TGCATGCGAGCATCGGCATCGCGCTCTACTCGGTCGCGAACGAAAGCGAAATCGACCTGCTGAAAAAAGCCGACCTCGCG
ATGTACAGCGCCAAGGACGCAGGCAAGAACTGCTATCAGTTCTACTCACCGCATCTGTCGCATCGCGCGGACCATCTGAT
GAAGTGGGAGCAGCAGTTGCGTGTCGCGCTGGCCGACCAGCAGCTGTTCCTCGCCTATCAGCCGAAGATCGACCTCGCGC
GCCGCTGCATCACCGGCTTCGAAGCGCTGGTGCGCTGGAACCATCCGCAGCATGGCCTGATTCCCGCGAACGAGTTCATC
CCTGTCGCCGAATCCACGGGTCTGATCGTCCCCATCGGCGATTTCGTGATCCGCACGGCGTGCCGGCAGCTTGCGCAGTG
GCAGCAACAGGGTTACGACACCCTGTCACTCGCCGTGAATATTTCGGCGGTACAGTTCTGGCGCGGCGATCTTTACGAAA
CGATTTCGCACGCAATCGAGGAAACGGGCATCGCCGCGCGCCGCCTCGAGCTCGAGATCACCGAGACGGCGATGATGGAG
TACCCGGATCTCGTCTCCGAAAAGATCTTCGCGCTGAAGCGGCTCGGCGTGCGCATCGCGCTCGACGACTTCGGCACCGG
CTATTCGTCGCTGTCGTACCTGAACCGCTTCTCGGTGGATACGCTGAAGGTCGACCGCTCGTTCGTGCAGGCCATTCCCG
GCGACCGCAGCGTCTGCGTAATGGTGACGGCCATCGTCAACCTCGCGCGCTCGCTGGGGCTGACGGTCGTGGTCGAAGGC
ACGGAGACGGAAGAACAGATCGCGTGGCTTGCCGCACTCGGCCATATCGAGGCGCAAGGTTTCCTGTTTTCGCGGCCCGT
GCCCGCCGAGGGTATTCCCGCGCTGCTCGAACGCTTCGGCGTGTGCGGCACGCACGGTGCGCATCTCACGCATCGCGGCG
ACGCCGTCAGCACCAGCGATGCCGCGAGCACCAGCACGAGCAACGAATCGGTCTGA

Upstream 100 bases:

>100_bases
TCGTCCAAACAGCCGGTTGCTTTAACATTCGCGCAGTCAACAGAAACGCACACACCGCCAAGCAAGCATAGCCGCAAGGC
ACAGGGTCACGGTCCAGCCG

Downstream 100 bases:

>100_bases
GCGCAGCACGCAGCAAGCGTCAGTGGATGCAACGCGTCGGCCGGAAGAATGAACGGTAGCAACGCAATTCGGGCGTATCC
GCTCGAGCGCGCATGACCCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MNQFRLSSARDVRHRLDPAGTRRRALLAIPALGVLVLVLLWTVIFARLSVEKDTTYREAMASAAILSAALEQHTVKAIHQ
VDQITRFVKFEFEKTPGHFDLASTVEKGVVQSETLVQVSLIDEHGKLIANTAEANPKPIDLSDREHFKVHEHENDDQLFI
SKPVLGRVSGHWTLQMTRRLNHPDGSFAGVVVVSEDPSYFTSDFYNNAAIGRDGVIAVISDSGAVLARRTGNSDHTQGVF
TATGVYPTSEHVSGTYVDSIDNVTRIVSYRHIDGYPLGVLVGLSQAEEFADYNHTRNVYLLMASFISLAMLGFFAVATGL
IGKLLGREREMTHLVEFDLLTGLRNRYSTLQSLRHEVGQPVNVGHLAILFIDLDNFKTVNDTLGHNAGDIVLQMTASRLA
DAVADAGALSRIGGDEFVVVIKGDDVEKRAVTLAEAIIDVFAKPFEVRGSSFVLHASIGIALYSVANESEIDLLKKADLA
MYSAKDAGKNCYQFYSPHLSHRADHLMKWEQQLRVALADQQLFLAYQPKIDLARRCITGFEALVRWNHPQHGLIPANEFI
PVAESTGLIVPIGDFVIRTACRQLAQWQQQGYDTLSLAVNISAVQFWRGDLYETISHAIEETGIAARRLELEITETAMME
YPDLVSEKIFALKRLGVRIALDDFGTGYSSLSYLNRFSVDTLKVDRSFVQAIPGDRSVCVMVTAIVNLARSLGLTVVVEG
TETEEQIAWLAALGHIEAQGFLFSRPVPAEGIPALLERFGVCGTHGAHLTHRGDAVSTSDAASTSTSNESV

Sequences:

>Translated_791_residues
MNQFRLSSARDVRHRLDPAGTRRRALLAIPALGVLVLVLLWTVIFARLSVEKDTTYREAMASAAILSAALEQHTVKAIHQ
VDQITRFVKFEFEKTPGHFDLASTVEKGVVQSETLVQVSLIDEHGKLIANTAEANPKPIDLSDREHFKVHEHENDDQLFI
SKPVLGRVSGHWTLQMTRRLNHPDGSFAGVVVVSEDPSYFTSDFYNNAAIGRDGVIAVISDSGAVLARRTGNSDHTQGVF
TATGVYPTSEHVSGTYVDSIDNVTRIVSYRHIDGYPLGVLVGLSQAEEFADYNHTRNVYLLMASFISLAMLGFFAVATGL
IGKLLGREREMTHLVEFDLLTGLRNRYSTLQSLRHEVGQPVNVGHLAILFIDLDNFKTVNDTLGHNAGDIVLQMTASRLA
DAVADAGALSRIGGDEFVVVIKGDDVEKRAVTLAEAIIDVFAKPFEVRGSSFVLHASIGIALYSVANESEIDLLKKADLA
MYSAKDAGKNCYQFYSPHLSHRADHLMKWEQQLRVALADQQLFLAYQPKIDLARRCITGFEALVRWNHPQHGLIPANEFI
PVAESTGLIVPIGDFVIRTACRQLAQWQQQGYDTLSLAVNISAVQFWRGDLYETISHAIEETGIAARRLELEITETAMME
YPDLVSEKIFALKRLGVRIALDDFGTGYSSLSYLNRFSVDTLKVDRSFVQAIPGDRSVCVMVTAIVNLARSLGLTVVVEG
TETEEQIAWLAALGHIEAQGFLFSRPVPAEGIPALLERFGVCGTHGAHLTHRGDAVSTSDAASTSTSNESV
>Mature_791_residues
MNQFRLSSARDVRHRLDPAGTRRRALLAIPALGVLVLVLLWTVIFARLSVEKDTTYREAMASAAILSAALEQHTVKAIHQ
VDQITRFVKFEFEKTPGHFDLASTVEKGVVQSETLVQVSLIDEHGKLIANTAEANPKPIDLSDREHFKVHEHENDDQLFI
SKPVLGRVSGHWTLQMTRRLNHPDGSFAGVVVVSEDPSYFTSDFYNNAAIGRDGVIAVISDSGAVLARRTGNSDHTQGVF
TATGVYPTSEHVSGTYVDSIDNVTRIVSYRHIDGYPLGVLVGLSQAEEFADYNHTRNVYLLMASFISLAMLGFFAVATGL
IGKLLGREREMTHLVEFDLLTGLRNRYSTLQSLRHEVGQPVNVGHLAILFIDLDNFKTVNDTLGHNAGDIVLQMTASRLA
DAVADAGALSRIGGDEFVVVIKGDDVEKRAVTLAEAIIDVFAKPFEVRGSSFVLHASIGIALYSVANESEIDLLKKADLA
MYSAKDAGKNCYQFYSPHLSHRADHLMKWEQQLRVALADQQLFLAYQPKIDLARRCITGFEALVRWNHPQHGLIPANEFI
PVAESTGLIVPIGDFVIRTACRQLAQWQQQGYDTLSLAVNISAVQFWRGDLYETISHAIEETGIAARRLELEITETAMME
YPDLVSEKIFALKRLGVRIALDDFGTGYSSLSYLNRFSVDTLKVDRSFVQAIPGDRSVCVMVTAIVNLARSLGLTVVVEG
TETEEQIAWLAALGHIEAQGFLFSRPVPAEGIPALLERFGVCGTHGAHLTHRGDAVSTSDAASTSTSNESV

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=426, Percent_Identity=35.6807511737089, Blast_Score=262, Evalue=6e-71,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=36.0730593607306, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI226510982, Length=387, Percent_Identity=31.266149870801, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=35.2, Blast_Score=159, Evalue=9e-40,
Organism=Escherichia coli, GI1787055, Length=426, Percent_Identity=26.7605633802817, Blast_Score=152, Evalue=9e-38,
Organism=Escherichia coli, GI1788502, Length=253, Percent_Identity=33.9920948616601, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786507, Length=239, Percent_Identity=35.1464435146443, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=33.0543933054393, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=31.9327731092437, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=32.295719844358, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788381, Length=396, Percent_Identity=26.5151515151515, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=30.4526748971193, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87082096, Length=152, Percent_Identity=33.5526315789474, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=170, Percent_Identity=33.5294117647059, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=34.9112426035503, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786584, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787802, Length=160, Percent_Identity=30.625, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=32.9268292682927, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=31.9018404907975, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=214, Percent_Identity=30.3738317757009, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=234, Percent_Identity=26.4957264957265, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787410, Length=232, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 86936; Mature: 86936

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFRLSSARDVRHRLDPAGTRRRALLAIPALGVLVLVLLWTVIFARLSVEKDTTYREAM
CCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ASAAILSAALEQHTVKAIHQVDQITRFVKFEFEKTPGHFDLASTVEKGVVQSETLVQVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCCCCEEEEEE
IDEHGKLIANTAEANPKPIDLSDREHFKVHEHENDDQLFISKPVLGRVSGHWTLQMTRRL
ECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCHHCCCCCEEEEEEECC
NHPDGSFAGVVVVSEDPSYFTSDFYNNAAIGRDGVIAVISDSGAVLARRTGNSDHTQGVF
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEE
TATGVYPTSEHVSGTYVDSIDNVTRIVSYRHIDGYPLGVLVGLSQAEEFADYNHTRNVYL
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHCCCCCHHHH
LMASFISLAMLGFFAVATGLIGKLLGREREMTHLVEFDLLTGLRNRYSTLQSLRHEVGQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNVGHLAILFIDLDNFKTVNDTLGHNAGDIVLQMTASRLADAVADAGALSRIGGDEFVVV
CCCCEEEEEEEECCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHCCHHHHHCCCCEEEEE
IKGDDVEKRAVTLAEAIIDVFAKPFEVRGSSFVLHASIGIALYSVANESEIDLLKKADLA
EECCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCEEEEECCCCCHHHHHHHHHHH
MYSAKDAGKNCYQFYSPHLSHRADHLMKWEQQLRVALADQQLFLAYQPKIDLARRCITGF
HEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
EALVRWNHPQHGLIPANEFIPVAESTGLIVPIGDFVIRTACRQLAQWQQQGYDTLSLAVN
HHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ISAVQFWRGDLYETISHAIEETGIAARRLELEITETAMMEYPDLVSEKIFALKRLGVRIA
EHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCCEEE
LDDFGTGYSSLSYLNRFSVDTLKVDRSFVQAIPGDRSVCVMVTAIVNLARSLGLTVVVEG
EECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEEC
TETEEQIAWLAALGHIEAQGFLFSRPVPAEGIPALLERFGVCGTHGAHLTHRGDAVSTSD
CCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCCC
AASTSTSNESV
CCCCCCCCCCC
>Mature Secondary Structure
MNQFRLSSARDVRHRLDPAGTRRRALLAIPALGVLVLVLLWTVIFARLSVEKDTTYREAM
CCCCCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ASAAILSAALEQHTVKAIHQVDQITRFVKFEFEKTPGHFDLASTVEKGVVQSETLVQVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCCCCCEEEEEE
IDEHGKLIANTAEANPKPIDLSDREHFKVHEHENDDQLFISKPVLGRVSGHWTLQMTRRL
ECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCHHCCCCCEEEEEEECC
NHPDGSFAGVVVVSEDPSYFTSDFYNNAAIGRDGVIAVISDSGAVLARRTGNSDHTQGVF
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEE
TATGVYPTSEHVSGTYVDSIDNVTRIVSYRHIDGYPLGVLVGLSQAEEFADYNHTRNVYL
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHHHHHCCCCCHHHH
LMASFISLAMLGFFAVATGLIGKLLGREREMTHLVEFDLLTGLRNRYSTLQSLRHEVGQP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNVGHLAILFIDLDNFKTVNDTLGHNAGDIVLQMTASRLADAVADAGALSRIGGDEFVVV
CCCCEEEEEEEECCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHCCHHHHHCCCCEEEEE
IKGDDVEKRAVTLAEAIIDVFAKPFEVRGSSFVLHASIGIALYSVANESEIDLLKKADLA
EECCCCHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCEEEEECCCCCHHHHHHHHHHH
MYSAKDAGKNCYQFYSPHLSHRADHLMKWEQQLRVALADQQLFLAYQPKIDLARRCITGF
HEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHH
EALVRWNHPQHGLIPANEFIPVAESTGLIVPIGDFVIRTACRQLAQWQQQGYDTLSLAVN
HHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ISAVQFWRGDLYETISHAIEETGIAARRLELEITETAMMEYPDLVSEKIFALKRLGVRIA
EHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCCEEE
LDDFGTGYSSLSYLNRFSVDTLKVDRSFVQAIPGDRSVCVMVTAIVNLARSLGLTVVVEG
EECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEEC
TETEEQIAWLAALGHIEAQGFLFSRPVPAEGIPALLERFGVCGTHGAHLTHRGDAVSTSD
CCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCCCC
AASTSTSNESV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]