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The map label for this gene is gluQ [H]

Identifier: 186476835

GI number: 186476835

Start: 2334689

End: 2335573

Strand: Direct

Name: gluQ [H]

Synonym: Bphy_2081

Alternate gene names: 186476835

Gene position: 2334689-2335573 (Clockwise)

Preceding gene: 186476834

Following gene: 186476842

Centisome position: 67.1

GC content: 68.36

Gene sequence:

>885_bases
ATGACGCGCTATCGCGGACGTTTCGCGCCCTCCCCCACGGGCCCGCTGCATGTCGGCTCGCTGGTCAGCGCACTCGCAAG
CTGGCTGGATGCGCGCGCCAATCGCGGCACGTGGCTGGTGCGTATCGAAGACATCGACGGGCCGCGCACCGTCCCGGGCG
CCGCGCAGCACATCCTCGATACGCTCACGCGCTTCGGCATGACGGCCGACGAACCGCCCGTCTGGCAAAGCCAGCGCGCA
GCGCTTTACCAGCAGGCATTCGAACGCCTGCAGGCCACAGGCCTCGTCTATCCCTGCGGCTGCACGCGCAAGGAAATCGC
CGATTCGCTGGTCCGGACCCACGCCCGGCACACGACGCTCGCCTACCCCGGCACCTGCCGCAACGGCCTGAACGGCAAGC
CCGCGCGCGCGTGGCGACTGCGTGTGCCGGACGGCGATGCCGCCATCGTGACGTTCGACGATCGCTGGCAAGGGCGGCAA
GTGCAGAATCTCGCCACTGAAGTCGGCGACTTCGTGCTGCGTCGCGCGGACGATCAGTGGGCCTATCAGCTGGCCGTGGT
CGTCGACGACGCGGATCAGGGCATCACCCACATTGTGCGCGGCGCCGACCTGCTCGACTCGACCGCCCGACAGATCTACC
TGCAGCGCTGCCTCGGCGTGGCCACGCCCTCCTACCTGCATGTGCCCGTCGTGACGAACGCCGACGGCGAAAAGCTCAGC
AAGCAGACGGGTGCCGCGGCCCTCGACGCATCGGAGCCGCTCGTCACGCTGAACCGTGCGGCGCGGCATCTGGGATTGAA
GCTGGGAGAAGCAGCGGCGACATCGCTCGATGCGTTCTACACGGAAGCCGTCGCGGCGTGGTCGGATCGCATCAGGCGGC
AATAA

Upstream 100 bases:

>100_bases
CCGCGCATGCAGCGGATCTGGTCTGAGCGCAGCGCGTCATCACCCGCTGCATGAACCCGTTTTGCATGCGCCGTGCCGCC
GCGGCTCACGACACCTGAAC

Downstream 100 bases:

>100_bases
CGCCGCGCCAACAAAGATGGCGCCCGAAAGGCGCCATTCGCAAAAGCAATCAGAACGGCAAGCGCTGCGACATCAATTCG
ACGACGTCGTCTTGCGCGGC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTRYRGRFAPSPTGPLHVGSLVSALASWLDARANRGTWLVRIEDIDGPRTVPGAAQHILDTLTRFGMTADEPPVWQSQRA
ALYQQAFERLQATGLVYPCGCTRKEIADSLVRTHARHTTLAYPGTCRNGLNGKPARAWRLRVPDGDAAIVTFDDRWQGRQ
VQNLATEVGDFVLRRADDQWAYQLAVVVDDADQGITHIVRGADLLDSTARQIYLQRCLGVATPSYLHVPVVTNADGEKLS
KQTGAAALDASEPLVTLNRAARHLGLKLGEAAATSLDAFYTEAVAAWSDRIRRQ

Sequences:

>Translated_294_residues
MTRYRGRFAPSPTGPLHVGSLVSALASWLDARANRGTWLVRIEDIDGPRTVPGAAQHILDTLTRFGMTADEPPVWQSQRA
ALYQQAFERLQATGLVYPCGCTRKEIADSLVRTHARHTTLAYPGTCRNGLNGKPARAWRLRVPDGDAAIVTFDDRWQGRQ
VQNLATEVGDFVLRRADDQWAYQLAVVVDDADQGITHIVRGADLLDSTARQIYLQRCLGVATPSYLHVPVVTNADGEKLS
KQTGAAALDASEPLVTLNRAARHLGLKLGEAAATSLDAFYTEAVAAWSDRIRRQ
>Mature_293_residues
TRYRGRFAPSPTGPLHVGSLVSALASWLDARANRGTWLVRIEDIDGPRTVPGAAQHILDTLTRFGMTADEPPVWQSQRAA
LYQQAFERLQATGLVYPCGCTRKEIADSLVRTHARHTTLAYPGTCRNGLNGKPARAWRLRVPDGDAAIVTFDDRWQGRQV
QNLATEVGDFVLRRADDQWAYQLAVVVDDADQGITHIVRGADLLDSTARQIYLQRCLGVATPSYLHVPVVTNADGEKLSK
QTGAAALDASEPLVTLNRAARHLGLKLGEAAATSLDAFYTEAVAAWSDRIRRQ

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=263, Percent_Identity=38.7832699619772, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI226510925, Length=266, Percent_Identity=45.8646616541353, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1788743, Length=277, Percent_Identity=34.2960288808664, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71993394, Length=296, Percent_Identity=30.7432432432432, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324540, Length=265, Percent_Identity=33.5849056603774, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24665321, Length=262, Percent_Identity=36.2595419847328, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 32238; Mature: 32107

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYRGRFAPSPTGPLHVGSLVSALASWLDARANRGTWLVRIEDIDGPRTVPGAAQHILD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHH
TLTRFGMTADEPPVWQSQRAALYQQAFERLQATGLVYPCGCTRKEIADSLVRTHARHTTL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCEE
AYPGTCRNGLNGKPARAWRLRVPDGDAAIVTFDDRWQGRQVQNLATEVGDFVLRRADDQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDADQGITHIVRGADLLDSTARQIYLQRCLGVATPSYLHVPVVTNADGEKLS
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHH
KQTGAAALDASEPLVTLNRAARHLGLKLGEAAATSLDAFYTEAVAAWSDRIRRQ
HHHCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRYRGRFAPSPTGPLHVGSLVSALASWLDARANRGTWLVRIEDIDGPRTVPGAAQHILD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHH
TLTRFGMTADEPPVWQSQRAALYQQAFERLQATGLVYPCGCTRKEIADSLVRTHARHTTL
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCEE
AYPGTCRNGLNGKPARAWRLRVPDGDAAIVTFDDRWQGRQVQNLATEVGDFVLRRADDQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDADQGITHIVRGADLLDSTARQIYLQRCLGVATPSYLHVPVVTNADGEKLS
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHH
KQTGAAALDASEPLVTLNRAARHLGLKLGEAAATSLDAFYTEAVAAWSDRIRRQ
HHHCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA