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The map label for this gene is exbB [H]

Identifier: 186476701

GI number: 186476701

Start: 2190984

End: 2191715

Strand: Direct

Name: exbB [H]

Synonym: Bphy_1946

Alternate gene names: 186476701

Gene position: 2190984-2191715 (Clockwise)

Preceding gene: 186476700

Following gene: 186476702

Centisome position: 62.97

GC content: 63.8

Gene sequence:

>732_bases
ATGCAGAATTACGGTATCGCCCACGTCTGGGCTCAAGGGGATTTCGTCACACGCGGTATCGCGCTGGCGCTGCTGATCAT
GTCGGTGCTGTCGTGGAGCGTGATCGTCGTCAAGAGCTGGAACGTGATGCGCCTGAACCGTCTGACCCGGAACGCCGAAA
AGGCCTTCTGGCATTCGGATGACTTCGCCGACGGCGCGAAGAAGCTCGGCAGCGACACGTCGTCGCCCACTGAAAACCCG
TTCCTCGCGCTCGCGCTGTCGGGCCAGGAAGCCGCGGATCACCATCATCAGACTCAGCCGCATCTGCACGACCGCATGGA
CGTGTCGGACTGGGTCACGCGCTGCCTGAAGGACACGATGGATGAAAGCGTTGCGCGCATGCAGGCCGGCCTCGCAATTC
TCGCGTCGATCGGCAGCACGGCGCCGTTCGTCGGCCTGTTCGGCACGGTGTGGGGCATCTATCACGCGCTGTTGACGATC
GGCGCGACTGGCCAGTCGTCGATTGATCAGGTTGCCGGTCCCGTCGGCGAAGCGCTCATCATGACGGCCTTCGGTCTGTT
CGTCGCGATCCCCGCCGTGCTCGGCTACAACGCGCTGACGCGCGCCAACAAAGGCATCGTCAGCAAGCTGAACCGGTTTG
CCCACGGTCTGCATGCGTTCTTCGTCACGGGCGCGCGCCTGTCGTCGTCGAAACGCGGCGACGGTCTTCGGCTCGCGACC
CGCACCAACTAA

Upstream 100 bases:

>100_bases
TGGACGGCGAAGCGACGCGCGTGCCTGCCGTCCAGCCGTTCGACTTCAGCCTGAACAACTGATCCGCCGGAAAAGATTTC
AAAGAAGAAAAGGAATTGCC

Downstream 100 bases:

>100_bases
ATAGCGAGGCATAGCGATGGCAATGAGCCCTTTTGCCGGCGACGAAGACGACGGCCTCATGAACGAGATCAACATGACGC
CCCTCGTCGACGTCATGTTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQNYGIAHVWAQGDFVTRGIALALLIMSVLSWSVIVVKSWNVMRLNRLTRNAEKAFWHSDDFADGAKKLGSDTSSPTENP
FLALALSGQEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDESVARMQAGLAILASIGSTAPFVGLFGTVWGIYHALLTI
GATGQSSIDQVAGPVGEALIMTAFGLFVAIPAVLGYNALTRANKGIVSKLNRFAHGLHAFFVTGARLSSSKRGDGLRLAT
RTN

Sequences:

>Translated_243_residues
MQNYGIAHVWAQGDFVTRGIALALLIMSVLSWSVIVVKSWNVMRLNRLTRNAEKAFWHSDDFADGAKKLGSDTSSPTENP
FLALALSGQEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDESVARMQAGLAILASIGSTAPFVGLFGTVWGIYHALLTI
GATGQSSIDQVAGPVGEALIMTAFGLFVAIPAVLGYNALTRANKGIVSKLNRFAHGLHAFFVTGARLSSSKRGDGLRLAT
RTN
>Mature_243_residues
MQNYGIAHVWAQGDFVTRGIALALLIMSVLSWSVIVVKSWNVMRLNRLTRNAEKAFWHSDDFADGAKKLGSDTSSPTENP
FLALALSGQEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDESVARMQAGLAILASIGSTAPFVGLFGTVWGIYHALLTI
GATGQSSIDQVAGPVGEALIMTAFGLFVAIPAVLGYNALTRANKGIVSKLNRFAHGLHAFFVTGARLSSSKRGDGLRLAT
RTN

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=207, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789381, Length=210, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26213; Mature: 26213

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNYGIAHVWAQGDFVTRGIALALLIMSVLSWSVIVVKSWNVMRLNRLTRNAEKAFWHSD
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCC
DFADGAKKLGSDTSSPTENPFLALALSGQEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DESVARMQAGLAILASIGSTAPFVGLFGTVWGIYHALLTIGATGQSSIDQVAGPVGEALI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MTAFGLFVAIPAVLGYNALTRANKGIVSKLNRFAHGLHAFFVTGARLSSSKRGDGLRLAT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RTN
CCC
>Mature Secondary Structure
MQNYGIAHVWAQGDFVTRGIALALLIMSVLSWSVIVVKSWNVMRLNRLTRNAEKAFWHSD
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCC
DFADGAKKLGSDTSSPTENPFLALALSGQEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DESVARMQAGLAILASIGSTAPFVGLFGTVWGIYHALLTIGATGQSSIDQVAGPVGEALI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MTAFGLFVAIPAVLGYNALTRANKGIVSKLNRFAHGLHAFFVTGARLSSSKRGDGLRLAT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
RTN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]