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The map label for this gene is tadA [H]

Identifier: 183222799

GI number: 183222799

Start: 3578955

End: 3579395

Strand: Direct

Name: tadA [H]

Synonym: LEPBI_I3460

Alternate gene names: 183222799

Gene position: 3578955-3579395 (Clockwise)

Preceding gene: 183222797

Following gene: 183222800

Centisome position: 99.42

GC content: 38.55

Gene sequence:

>441_bases
GTGGATTTCTATGAATCGTTTCTAAAACGATATTCGATAGAAGTTTCCAAGTACAAAAACGAAATTCCCTCTTATTCTGA
AATCATCACAAAGGATGGAAACTTAGTTTCCTCTTCTTTTAATTCCGTCGAACAGACATTAAATCCGACTAAACATAGCG
AAATTTTAGCAATTGAGAAGGCATTGTCTCATGTGGATGGTAGATACCTTTCAGAACATATCCTCATCACTGCTCTTGAG
CCATGTATTCTTTGTGCGGGTGCCGTTGTGCGGGTGAAACTTCCAGAAGTGGTCTATTTTCTACCGGCAAAGCCGGGAGA
AGGTATTTCCTCTTACACAACCGAATCAATTTATCTGCTGAATCATTTTCCAAAATGCACTCTCATTCCAGAGTCGCGCA
TAAAATTTGAATTTCTGAGTTTTTTCAAAGAGAAAAGGTAG

Upstream 100 bases:

>100_bases
GGTAAAAATGCTCCAAGCATTCATTGCGCCCATAGCTCAACTGGATAGAGTATCTGACTACGGATCAGAAGGTTAGAGGT
TCAAATCCTCTTGGGCGCGC

Downstream 100 bases:

>100_bases
AATTCTAAAGACCGTTTCTTTTTATGGAAGCCAGTAGAAATCACTGGAGAGATGTCAGAGTGGTCTATTGTGCATGCTTG
GAAAGCATGTGTGCCAAAAG

Product: putative cytidine/adenosine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPTKHSEILAIEKALSHVDGRYLSEHILITALE
PCILCAGAVVRVKLPEVVYFLPAKPGEGISSYTTESIYLLNHFPKCTLIPESRIKFEFLSFFKEKR

Sequences:

>Translated_146_residues
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPTKHSEILAIEKALSHVDGRYLSEHILITALE
PCILCAGAVVRVKLPEVVYFLPAKPGEGISSYTTESIYLLNHFPKCTLIPESRIKFEFLSFFKEKR
>Mature_146_residues
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPTKHSEILAIEKALSHVDGRYLSEHILITALE
PCILCAGAVVRVKLPEVVYFLPAKPGEGISSYTTESIYLLNHFPKCTLIPESRIKFEFLSFFKEKR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 16674; Mature: 16674

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPTKHSEILAIEK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ALSHVDGRYLSEHILITALEPCILCAGAVVRVKLPEVVYFLPAKPGEGISSYTTESIYLL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHCCCEEEEE
NHFPKCTLIPESRIKFEFLSFFKEKR
ECCCCEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPTKHSEILAIEK
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ALSHVDGRYLSEHILITALEPCILCAGAVVRVKLPEVVYFLPAKPGEGISSYTTESIYLL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHCCCEEEEE
NHFPKCTLIPESRIKFEFLSFFKEKR
ECCCCEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]