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The map label for this gene is aglA [H]

Identifier: 183222730

GI number: 183222730

Start: 3507104

End: 3508732

Strand: Direct

Name: aglA [H]

Synonym: LEPBI_I3386

Alternate gene names: 183222730

Gene position: 3507104-3508732 (Clockwise)

Preceding gene: 183222729

Following gene: 183222731

Centisome position: 97.43

GC content: 40.82

Gene sequence:

>1629_bases
ATGGCATGGTGGAAAGAAGCAGTCATCTATCAAATTTATCCACGTAGTTTCCAAGATTCCAATGGAGATGGCATCGGCGA
TTTAGAAGGAATCATCCAACGATTGGATTATTTAGCAGGTTCCAGAGATTCTCTTGGAATCGATGCCATTTGGTTATCTC
CTGTGTATCCTTCTCCCATGTTTGATTTTGGATATGATATTTCAGATTACGAAGAAATTGATCCAGTCTTTGGTGACATT
CAGACCTTTAAACGTCTGTTAAAGGAAGCACACAAACGTGGAATCCGTATTATCATGGATTTAGTGGTCAACCATACATC
TCATTTACACCCATGGTTTATTGAATCTAGATCATCTGTCAATAGCCCCAAACGGGATTGGTACATTTGGAAAGAACCAA
GTCATAATGGTCCGCCGAATAATTGGTTAGGTGCATTCGGTGGTTCTGGTTGGGAATATGACAAACGAAGTGGTGAATAT
TATTTCCATTCTTTTTTAAAAGAACAACCAGATCTCAATTGGCGTAATCCCGATGTAGAGGATGCCATTTTCCGAATGAT
GAAATATTGGCTCGATATGGGAGTTGATGGGTTTCGTTTGGATGTTGTGAATCTATACGTCAAAGATGAATTCTTTCGAA
ACAATGCATCCTATTTTATGAAAGGCCCAAGGCCTTACGACAAACAAGTACATACCTACGACCGTGACCGTCCTGAAATG
CATGGAATATTGCGAAGGATGCGTAAACTTTTAGATTCCTATTCCGATAAACGTATGTTTGTTGGTGAGATCATGCAAGA
TTTTCCGGGAAATGTGTTGTTACCCGCCACCTATTGTGGCCGTAACGACGAACTCCACCTTGCTTTCAATTTTATGTTTT
TGTTTTCACCATGGAAAGCAGAACGGTTTTTCCAGATTGTGAAAGATTTTGAATCTGCGTTAGGTGATGACAATTGGCCC
AATTATACTTTGTCGAACCATGATTTCCCTCGTCACATCACTCGGTATGAAAAAGGAGAACATACTTTAGACCGTGCCAG
GCTTGCCGCCTGTATGATGTTAACGTTACGAGGAACACCTTTTCTGTATTACGGCGAAGAGATTGGAATGAAACGCCAAA
AAGTTCCCTTTAACAAAATCCAAGACCCTGTGGGAAAACGGTATTGGCCATTCCATCCCGGTCGAGATCCCGAAAGAATT
CCCATGCCTTGGGACGGGTCTGAGACCACAGGTTTTACCACGGGAAAACCTTGGTTACCTCTCTACACAGAAGCTAACAC
AATCAATGTGGATGCACAAAAACAAAACCCCGATTCCCTGTTTTATACCTATAAGAAACTACTCCAAATCCGAAAGGATC
GTAAGTCCCTCCGGAAAGGAAAATTAAAGATTTTACTTAGCGCCGACAAACAAGCATTATACTACAGACGTAGGGACGGC
AAGGAAGAAACGTATATCTTTTTAAACTTTTCCTCCAAACCTGTCAGTGTTTCGTATCCAAGAAAATGGAGTTTGAATGA
AATTTTATTTAGTTCTAAAAATCGAGATGCCTCGTTTGAATTAGATAAGGAGCTCGATACTGGCGATTTGGTTTTGTTGC
CGAATGAGGCTGTGATTTTCGGGAATTAA

Upstream 100 bases:

>100_bases
AAAATAGAAGATACAGGACTTCTGCTGGCGATCAAAGAAAAAATTCTCTCAGTCGCAAGAGTCAAAGAAAACCAAGGTAT
CATGGAGATTAGTTTTTAAT

Downstream 100 bases:

>100_bases
GGAAAGTCTATTCAACGCTATCTTTCCACTTTTGTCCTTTTTAGATAAGTCTAACAAAAGAAGGAAAGGATATCTGATAC
AATCGACTCTTCGATAAACT

Product: putative alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MAWWKEAVIYQIYPRSFQDSNGDGIGDLEGIIQRLDYLAGSRDSLGIDAIWLSPVYPSPMFDFGYDISDYEEIDPVFGDI
QTFKRLLKEAHKRGIRIIMDLVVNHTSHLHPWFIESRSSVNSPKRDWYIWKEPSHNGPPNNWLGAFGGSGWEYDKRSGEY
YFHSFLKEQPDLNWRNPDVEDAIFRMMKYWLDMGVDGFRLDVVNLYVKDEFFRNNASYFMKGPRPYDKQVHTYDRDRPEM
HGILRRMRKLLDSYSDKRMFVGEIMQDFPGNVLLPATYCGRNDELHLAFNFMFLFSPWKAERFFQIVKDFESALGDDNWP
NYTLSNHDFPRHITRYEKGEHTLDRARLAACMMLTLRGTPFLYYGEEIGMKRQKVPFNKIQDPVGKRYWPFHPGRDPERI
PMPWDGSETTGFTTGKPWLPLYTEANTINVDAQKQNPDSLFYTYKKLLQIRKDRKSLRKGKLKILLSADKQALYYRRRDG
KEETYIFLNFSSKPVSVSYPRKWSLNEILFSSKNRDASFELDKELDTGDLVLLPNEAVIFGN

Sequences:

>Translated_542_residues
MAWWKEAVIYQIYPRSFQDSNGDGIGDLEGIIQRLDYLAGSRDSLGIDAIWLSPVYPSPMFDFGYDISDYEEIDPVFGDI
QTFKRLLKEAHKRGIRIIMDLVVNHTSHLHPWFIESRSSVNSPKRDWYIWKEPSHNGPPNNWLGAFGGSGWEYDKRSGEY
YFHSFLKEQPDLNWRNPDVEDAIFRMMKYWLDMGVDGFRLDVVNLYVKDEFFRNNASYFMKGPRPYDKQVHTYDRDRPEM
HGILRRMRKLLDSYSDKRMFVGEIMQDFPGNVLLPATYCGRNDELHLAFNFMFLFSPWKAERFFQIVKDFESALGDDNWP
NYTLSNHDFPRHITRYEKGEHTLDRARLAACMMLTLRGTPFLYYGEEIGMKRQKVPFNKIQDPVGKRYWPFHPGRDPERI
PMPWDGSETTGFTTGKPWLPLYTEANTINVDAQKQNPDSLFYTYKKLLQIRKDRKSLRKGKLKILLSADKQALYYRRRDG
KEETYIFLNFSSKPVSVSYPRKWSLNEILFSSKNRDASFELDKELDTGDLVLLPNEAVIFGN
>Mature_541_residues
AWWKEAVIYQIYPRSFQDSNGDGIGDLEGIIQRLDYLAGSRDSLGIDAIWLSPVYPSPMFDFGYDISDYEEIDPVFGDIQ
TFKRLLKEAHKRGIRIIMDLVVNHTSHLHPWFIESRSSVNSPKRDWYIWKEPSHNGPPNNWLGAFGGSGWEYDKRSGEYY
FHSFLKEQPDLNWRNPDVEDAIFRMMKYWLDMGVDGFRLDVVNLYVKDEFFRNNASYFMKGPRPYDKQVHTYDRDRPEMH
GILRRMRKLLDSYSDKRMFVGEIMQDFPGNVLLPATYCGRNDELHLAFNFMFLFSPWKAERFFQIVKDFESALGDDNWPN
YTLSNHDFPRHITRYEKGEHTLDRARLAACMMLTLRGTPFLYYGEEIGMKRQKVPFNKIQDPVGKRYWPFHPGRDPERIP
MPWDGSETTGFTTGKPWLPLYTEANTINVDAQKQNPDSLFYTYKKLLQIRKDRKSLRKGKLKILLSADKQALYYRRRDGK
EETYIFLNFSSKPVSVSYPRKWSLNEILFSSKNRDASFELDKELDTGDLVLLPNEAVIFGN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=511, Percent_Identity=33.2681017612524, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1790687, Length=526, Percent_Identity=36.6920152091255, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1786604, Length=554, Percent_Identity=22.7436823104693, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32565753, Length=480, Percent_Identity=25.4166666666667, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25147709, Length=589, Percent_Identity=23.9388794567063, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6322245, Length=561, Percent_Identity=34.5811051693405, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321726, Length=610, Percent_Identity=33.6065573770492, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6319776, Length=562, Percent_Identity=34.3416370106762, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6321731, Length=566, Percent_Identity=34.2756183745583, Blast_Score=270, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6324416, Length=600, Percent_Identity=34.1666666666667, Blast_Score=266, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6322241, Length=596, Percent_Identity=33.5570469798658, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6322021, Length=596, Percent_Identity=33.5570469798658, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24583747, Length=490, Percent_Identity=37.3469387755102, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24583749, Length=490, Percent_Identity=37.3469387755102, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24586593, Length=513, Percent_Identity=34.1130604288499, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24586599, Length=573, Percent_Identity=34.0314136125654, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI45549022, Length=533, Percent_Identity=34.7091932457786, Blast_Score=291, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24586597, Length=577, Percent_Identity=34.1421143847487, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24583745, Length=566, Percent_Identity=32.1554770318021, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI221330053, Length=527, Percent_Identity=34.7248576850095, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24586591, Length=570, Percent_Identity=30.8771929824561, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24586587, Length=480, Percent_Identity=34.375, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586589, Length=576, Percent_Identity=31.7708333333333, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI281360393, Length=454, Percent_Identity=30.8370044052863, Blast_Score=221, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 63864; Mature: 63733

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWWKEAVIYQIYPRSFQDSNGDGIGDLEGIIQRLDYLAGSRDSLGIDAIWLSPVYPSPM
CCCHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
FDFGYDISDYEEIDPVFGDIQTFKRLLKEAHKRGIRIIMDLVVNHTSHLHPWFIESRSSV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCC
NSPKRDWYIWKEPSHNGPPNNWLGAFGGSGWEYDKRSGEYYFHSFLKEQPDLNWRNPDVE
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
DAIFRMMKYWLDMGVDGFRLDVVNLYVKDEFFRNNASYFMKGPRPYDKQVHTYDRDRPEM
HHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHH
HGILRRMRKLLDSYSDKRMFVGEIMQDFPGNVLLPATYCGRNDELHLAFNFMFLFSPWKA
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCCCEEEEEEEEEEECCCCH
ERFFQIVKDFESALGDDNWPNYTLSNHDFPRHITRYEKGEHTLDRARLAACMMLTLRGTP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
FLYYGEEIGMKRQKVPFNKIQDPVGKRYWPFHPGRDPERIPMPWDGSETTGFTTGKPWLP
EEEECHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LYTEANTINVDAQKQNPDSLFYTYKKLLQIRKDRKSLRKGKLKILLSADKQALYYRRRDG
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCC
KEETYIFLNFSSKPVSVSYPRKWSLNEILFSSKNRDASFELDKELDTGDLVLLPNEAVIF
CCCEEEEEEECCCCEEECCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCEEEE
GN
CC
>Mature Secondary Structure 
AWWKEAVIYQIYPRSFQDSNGDGIGDLEGIIQRLDYLAGSRDSLGIDAIWLSPVYPSPM
CCHHCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
FDFGYDISDYEEIDPVFGDIQTFKRLLKEAHKRGIRIIMDLVVNHTSHLHPWFIESRSSV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCC
NSPKRDWYIWKEPSHNGPPNNWLGAFGGSGWEYDKRSGEYYFHSFLKEQPDLNWRNPDVE
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
DAIFRMMKYWLDMGVDGFRLDVVNLYVKDEFFRNNASYFMKGPRPYDKQVHTYDRDRPEM
HHHHHHHHHHHHCCCCCEEEEEEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHH
HGILRRMRKLLDSYSDKRMFVGEIMQDFPGNVLLPATYCGRNDELHLAFNFMFLFSPWKA
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHCCCCCCCEEEEEEEEEEECCCCH
ERFFQIVKDFESALGDDNWPNYTLSNHDFPRHITRYEKGEHTLDRARLAACMMLTLRGTP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
FLYYGEEIGMKRQKVPFNKIQDPVGKRYWPFHPGRDPERIPMPWDGSETTGFTTGKPWLP
EEEECHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LYTEANTINVDAQKQNPDSLFYTYKKLLQIRKDRKSLRKGKLKILLSADKQALYYRRRDG
EEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCC
KEETYIFLNFSSKPVSVSYPRKWSLNEILFSSKNRDASFELDKELDTGDLVLLPNEAVIF
CCCEEEEEEECCCCEEECCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCEEEECCCEEEE
GN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]