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The map label for this gene is tpn50 [H]

Identifier: 183222506

GI number: 183222506

Start: 3273455

End: 3274882

Strand: Direct

Name: tpn50 [H]

Synonym: LEPBI_I3161

Alternate gene names: 183222506

Gene position: 3273455-3274882 (Clockwise)

Preceding gene: 183222504

Following gene: 183222509

Centisome position: 90.94

GC content: 40.83

Gene sequence:

>1428_bases
GTGAAGACCAAAATGCGTTCCCTCTTGCTCTGTTTTGTCACAATCCTTCCTCTTTTGGAATTGTTTGCCAATCCTTCTGG
AAAAACCCATTTCCAATGGAAATGGGCAACAAACCAGGTATTGGAACTGAACGAATACCATGATGTCCTTTTCCGAGTGG
GAACCAAAACTGTCGAACGAGAAGACAAAAACCGAGTGGTGATGAAAACCAGACAATGTTCGCAAGACTCTTGTTTGGTG
AACGCTTGGTTTGATACATATATGCGATATGGTAAAACATCGGGTCCATTTTGGAAGGACAAAGAATTTGTATCCGACTT
CACATTGTTTCGCAATGGCCGTTATGAAGTGCCCAATGAATTCATTATGCCTAACCTACGTAGTTTTCCTTCTTTCCCTG
ATTCACCGCTATCGGTATCCGATGTTTGGAAACTACCAGCAGAGGAGTCCTTTGATTTTTCTTCCGAACGCATCCGAGTG
AAAGTGACTCCTGAATATACCTTCCAAGGGATTTTTCCATGGAAAGAAGGGAACTACTCTGGCAATTGCGAAAAAATCAC
ATACACTTATCCCATTTTTTATTCCAAACCAGAATCTGAAAAAATGGCACCTAACGTGCCTTATAAGATTTTTGGGTTTG
CTACCGGTACCGTATTTTTTAACGCCGAAAAAGGAGTTCCTGAATTTAAGGAAGTCAAACTTTCCTATACATTCATTTAT
CCCAATGGGACTGTCCAAGAAGCAAACTTCCTCGTGAAGGGGGTATATTTCTTAAGAAACCAAGTGAATGCCAAAGACAA
AGAGTCAATCCGTGAAGACATCTTAAATGATTTGATTGTAGGTTATACAAGGGATGGTCTCCCCAATGGGAAACGCATCC
AAAAAAGGCAACGGCCTGGATTGGGAGATCCAAATCAAAACCTGGAAGGAAGATTGCCACCACAATCGACAGAGATCCCA
GAAATGACAGATGGTGTCACTCACCCAGATGTGAAAGAAAATCCAGATCCAAATTCACCAATCGATGACCCAAATCAAAT
TGCAGAACAACTGCCAGTGAAAGTTCGCACCACAGAGGATGGAATCGTGTTTTCCTTAGATTCCATTTTATTTGATTTTA
ATGATAGCAAACTAAAGGTCGATGCGGAATCGGCTGTGGCAAAAATTGCAGAAATTTTAAAAAAATACCCTGACCGCGAA
ATCAGAGTTTCGGGACATACGGACAATATTGGAAAAAAAGAATACAATCAAAAACTTTCAGAAGAGAGAGCAAAGTCCGT
TTTGCATTCGTTAGTCGACAATCACAAAATGGATGAAAAACATATCTCCTTTCGTGGGTATGCGGATGAATTTCCAGTCG
CGCCCAATGATTCAGAAGAAAATCGGCACAAAAACAGAAGGGTAGAAATCACTCTCGTTCTAGATTAA

Upstream 100 bases:

>100_bases
TCAGGTAAAGCCCAAATTCCGTCCTCCGTCAATCGCAAAAAGGCGCGGTTTTTTCCAATTCCACCCTCAGTTTTTATGAA
AAAACCCCGATCTTTGCAAA

Downstream 100 bases:

>100_bases
CCAATTTGTAAATCGAGTCCCACCGAATAAGGAGGGACCAAAGGTTCACTTTCCTTTTTCCCACGCTCCAATAGTTTTTC
CATTTCCTTTCGAATATCAC

Product: hypothetical protein

Products: NA

Alternate protein names: Antigen tpp57 [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MKTKMRSLLLCFVTILPLLELFANPSGKTHFQWKWATNQVLELNEYHDVLFRVGTKTVEREDKNRVVMKTRQCSQDSCLV
NAWFDTYMRYGKTSGPFWKDKEFVSDFTLFRNGRYEVPNEFIMPNLRSFPSFPDSPLSVSDVWKLPAEESFDFSSERIRV
KVTPEYTFQGIFPWKEGNYSGNCEKITYTYPIFYSKPESEKMAPNVPYKIFGFATGTVFFNAEKGVPEFKEVKLSYTFIY
PNGTVQEANFLVKGVYFLRNQVNAKDKESIREDILNDLIVGYTRDGLPNGKRIQKRQRPGLGDPNQNLEGRLPPQSTEIP
EMTDGVTHPDVKENPDPNSPIDDPNQIAEQLPVKVRTTEDGIVFSLDSILFDFNDSKLKVDAESAVAKIAEILKKYPDRE
IRVSGHTDNIGKKEYNQKLSEERAKSVLHSLVDNHKMDEKHISFRGYADEFPVAPNDSEENRHKNRRVEITLVLD

Sequences:

>Translated_475_residues
MKTKMRSLLLCFVTILPLLELFANPSGKTHFQWKWATNQVLELNEYHDVLFRVGTKTVEREDKNRVVMKTRQCSQDSCLV
NAWFDTYMRYGKTSGPFWKDKEFVSDFTLFRNGRYEVPNEFIMPNLRSFPSFPDSPLSVSDVWKLPAEESFDFSSERIRV
KVTPEYTFQGIFPWKEGNYSGNCEKITYTYPIFYSKPESEKMAPNVPYKIFGFATGTVFFNAEKGVPEFKEVKLSYTFIY
PNGTVQEANFLVKGVYFLRNQVNAKDKESIREDILNDLIVGYTRDGLPNGKRIQKRQRPGLGDPNQNLEGRLPPQSTEIP
EMTDGVTHPDVKENPDPNSPIDDPNQIAEQLPVKVRTTEDGIVFSLDSILFDFNDSKLKVDAESAVAKIAEILKKYPDRE
IRVSGHTDNIGKKEYNQKLSEERAKSVLHSLVDNHKMDEKHISFRGYADEFPVAPNDSEENRHKNRRVEITLVLD
>Mature_475_residues
MKTKMRSLLLCFVTILPLLELFANPSGKTHFQWKWATNQVLELNEYHDVLFRVGTKTVEREDKNRVVMKTRQCSQDSCLV
NAWFDTYMRYGKTSGPFWKDKEFVSDFTLFRNGRYEVPNEFIMPNLRSFPSFPDSPLSVSDVWKLPAEESFDFSSERIRV
KVTPEYTFQGIFPWKEGNYSGNCEKITYTYPIFYSKPESEKMAPNVPYKIFGFATGTVFFNAEKGVPEFKEVKLSYTFIY
PNGTVQEANFLVKGVYFLRNQVNAKDKESIREDILNDLIVGYTRDGLPNGKRIQKRQRPGLGDPNQNLEGRLPPQSTEIP
EMTDGVTHPDVKENPDPNSPIDDPNQIAEQLPVKVRTTEDGIVFSLDSILFDFNDSKLKVDAESAVAKIAEILKKYPDRE
IRVSGHTDNIGKKEYNQKLSEERAKSVLHSLVDNHKMDEKHISFRGYADEFPVAPNDSEENRHKNRRVEITLVLD

Specific function: Could function as a porin [H]

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=121, Percent_Identity=33.8842975206612, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788957, Length=107, Percent_Identity=30.8411214953271, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA [H]

EC number: NA

Molecular weight: Translated: 54796; Mature: 54796

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKMRSLLLCFVTILPLLELFANPSGKTHFQWKWATNQVLELNEYHDVLFRVGTKTVER
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHCCHHHHC
EDKNRVVMKTRQCSQDSCLVNAWFDTYMRYGKTSGPFWKDKEFVSDFTLFRNGRYEVPNE
CCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
FIMPNLRSFPSFPDSPLSVSDVWKLPAEESFDFSSERIRVKVTPEYTFQGIFPWKEGNYS
HHCCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCC
GNCEKITYTYPIFYSKPESEKMAPNVPYKIFGFATGTVFFNAEKGVPEFKEVKLSYTFIY
CCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHEEEEEEEEEC
PNGTVQEANFLVKGVYFLRNQVNAKDKESIREDILNDLIVGYTRDGLPNGKRIQKRQRPG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
LGDPNQNLEGRLPPQSTEIPEMTDGVTHPDVKENPDPNSPIDDPNQIAEQLPVKVRTTED
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCC
GIVFSLDSILFDFNDSKLKVDAESAVAKIAEILKKYPDREIRVSGHTDNIGKKEYNQKLS
CEEEEEEHEEEECCCCEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
EERAKSVLHSLVDNHKMDEKHISFRGYADEFPVAPNDSEENRHKNRRVEITLVLD
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEEC
>Mature Secondary Structure
MKTKMRSLLLCFVTILPLLELFANPSGKTHFQWKWATNQVLELNEYHDVLFRVGTKTVER
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHCCHHHHC
EDKNRVVMKTRQCSQDSCLVNAWFDTYMRYGKTSGPFWKDKEFVSDFTLFRNGRYEVPNE
CCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
FIMPNLRSFPSFPDSPLSVSDVWKLPAEESFDFSSERIRVKVTPEYTFQGIFPWKEGNYS
HHCCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCC
GNCEKITYTYPIFYSKPESEKMAPNVPYKIFGFATGTVFFNAEKGVPEFKEVKLSYTFIY
CCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCHHHEEEEEEEEEC
PNGTVQEANFLVKGVYFLRNQVNAKDKESIREDILNDLIVGYTRDGLPNGKRIQKRQRPG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
LGDPNQNLEGRLPPQSTEIPEMTDGVTHPDVKENPDPNSPIDDPNQIAEQLPVKVRTTED
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCC
GIVFSLDSILFDFNDSKLKVDAESAVAKIAEILKKYPDREIRVSGHTDNIGKKEYNQKLS
CEEEEEEHEEEECCCCEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
EERAKSVLHSLVDNHKMDEKHISFRGYADEFPVAPNDSEENRHKNRRVEITLVLD
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8112835; 7623668; 9665876 [H]