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The map label for this gene is frc [H]

Identifier: 183222256

GI number: 183222256

Start: 3002528

End: 3003676

Strand: Reverse

Name: frc [H]

Synonym: LEPBI_I2907

Alternate gene names: 183222256

Gene position: 3003676-3002528 (Counterclockwise)

Preceding gene: 183222258

Following gene: 183222255

Centisome position: 83.44

GC content: 41.17

Gene sequence:

>1149_bases
GTGAAAGTCGTTGATTTGTCCTTACTCCTTCCAGGCCCCCTTTGTTCCCAACACCTTGCTGATATGGGAGCCGAGGTGAT
TAAAGTCGAAAACCCACGCGCTTATGATGGGTCGCGAGCAATGTTCAAAGGGAAAACAGGTTATCCTGCTCTTTTTATGA
TGCTCAATCGAAATAAAAAAGCGATCACACTCAACTTAAAGAGAGAGCAAGCCAAAGAGATTTTGTTCAAACTCTTAGAA
GATGCAGATATCCTTTTGGAAGGATTTCGTCCCGATGGAATGGATAAAATGGGAATCGGTTATGATGTCTTAAAAGAAAA
ATTCCCTCGTTTGATTTACTGTGGGATCTCCGGATACGGGACGAGTGGTAAGTATGTAGACTTTGCGGGTCATGATTTGA
ATTATTTGGCCATCTCTGGTGTGCTTGACCAAACAGGAAATCCACCGAGACCGGCTGGGTTCCAAATGGCCGATGTCGGT
GGGGGAACACTCACTGCTCTTTCTGCCATCCTTGCCGCTTTGTACTACCGAGAAAAAACAGGCAAAGGACAAAAAATTGA
TATCTCGATGACCGATGCCTCCCTTCAATTCATTGCTTTGTACGGAGGGATTTTATCCGCATCTGGTGTTTCTCCCGAAG
CAGGCAATGATATCCTATCTGGTAAATTACCAAATTATAATGTGTATGAAACAAAAGAAGGTCGTTATGTTGCCCTAGGT
GCTTTGGAAGATATGTTTTTCCAAACTTTCTTAAGAGCAGCTGGGATGGATACCTTAACCAAAGACCATCCAATGACAGA
AGAAAATTTTGCTATCATCAAACAAAAGTTAACTGATTTTTTTAAATCAAAAACCTTTGCCGATTTGCAACCCATATTTG
ATAATACGGATGCTTGCCTTTCTCCCATTTTGAATATGAAGGAAGTGTCTGAAGATGCCAATATGAAAGAACGTGGGATG
ATTCTCGAAAGGAATCACCCTAAGTATGGACCAATTTTACAATTTGGATCTCCATTTCATTTTTCAGAAACTCCATTTGT
CTATCGAAATGACCCACCGGAACATGGAGAACATACCGAGGATATTTTAACCCAATTGGGGTTTTCGAAAGATCAGATTT
CAGGATTCAAAAAAGACCGAGTCGTTTAA

Upstream 100 bases:

>100_bases
ACGAGAAAAAAGCCCCAAATTAGAAAAAAATTTCCAGGATATGCAATAAAATATGAAGCAAGACAATCTAAATCCAAACA
AAAAAGGACCACTCTCAGGA

Downstream 100 bases:

>100_bases
CCGAGCCTTGCTTTTTTTTGAGAACTTCTGTACTTTGTCCTAGGGGAGAGGTAAACTCTCCCTGAAACAACGACATATGA
AGTACTTACAAGTATCTGAC

Product: putative formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKVVDLSLLLPGPLCSQHLADMGAEVIKVENPRAYDGSRAMFKGKTGYPALFMMLNRNKKAITLNLKREQAKEILFKLLE
DADILLEGFRPDGMDKMGIGYDVLKEKFPRLIYCGISGYGTSGKYVDFAGHDLNYLAISGVLDQTGNPPRPAGFQMADVG
GGTLTALSAILAALYYREKTGKGQKIDISMTDASLQFIALYGGILSASGVSPEAGNDILSGKLPNYNVYETKEGRYVALG
ALEDMFFQTFLRAAGMDTLTKDHPMTEENFAIIKQKLTDFFKSKTFADLQPIFDNTDACLSPILNMKEVSEDANMKERGM
ILERNHPKYGPILQFGSPFHFSETPFVYRNDPPEHGEHTEDILTQLGFSKDQISGFKKDRVV

Sequences:

>Translated_382_residues
MKVVDLSLLLPGPLCSQHLADMGAEVIKVENPRAYDGSRAMFKGKTGYPALFMMLNRNKKAITLNLKREQAKEILFKLLE
DADILLEGFRPDGMDKMGIGYDVLKEKFPRLIYCGISGYGTSGKYVDFAGHDLNYLAISGVLDQTGNPPRPAGFQMADVG
GGTLTALSAILAALYYREKTGKGQKIDISMTDASLQFIALYGGILSASGVSPEAGNDILSGKLPNYNVYETKEGRYVALG
ALEDMFFQTFLRAAGMDTLTKDHPMTEENFAIIKQKLTDFFKSKTFADLQPIFDNTDACLSPILNMKEVSEDANMKERGM
ILERNHPKYGPILQFGSPFHFSETPFVYRNDPPEHGEHTEDILTQLGFSKDQISGFKKDRVV
>Mature_382_residues
MKVVDLSLLLPGPLCSQHLADMGAEVIKVENPRAYDGSRAMFKGKTGYPALFMMLNRNKKAITLNLKREQAKEILFKLLE
DADILLEGFRPDGMDKMGIGYDVLKEKFPRLIYCGISGYGTSGKYVDFAGHDLNYLAISGVLDQTGNPPRPAGFQMADVG
GGTLTALSAILAALYYREKTGKGQKIDISMTDASLQFIALYGGILSASGVSPEAGNDILSGKLPNYNVYETKEGRYVALG
ALEDMFFQTFLRAAGMDTLTKDHPMTEENFAIIKQKLTDFFKSKTFADLQPIFDNTDACLSPILNMKEVSEDANMKERGM
ILERNHPKYGPILQFGSPFHFSETPFVYRNDPPEHGEHTEDILTQLGFSKDQISGFKKDRVV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI42794625, Length=393, Percent_Identity=35.3689567430025, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI266456254, Length=393, Percent_Identity=35.3689567430025, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI266458393, Length=296, Percent_Identity=35.8108108108108, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI300863128, Length=377, Percent_Identity=30.2387267904509, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI266458397, Length=259, Percent_Identity=37.0656370656371, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI300863124, Length=403, Percent_Identity=28.5359801488834, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI300863126, Length=372, Percent_Identity=26.6129032258064, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI13376042, Length=403, Percent_Identity=26.302729528536, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI42822893, Length=141, Percent_Identity=41.8439716312057, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI266458395, Length=141, Percent_Identity=41.8439716312057, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788717, Length=417, Percent_Identity=30.4556354916067, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87082093, Length=350, Percent_Identity=31.1428571428571, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786222, Length=395, Percent_Identity=25.5696202531646, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32564160, Length=320, Percent_Identity=32.1875, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI115535051, Length=314, Percent_Identity=30.2547770700637, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24648431, Length=395, Percent_Identity=31.8987341772152, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24585488, Length=344, Percent_Identity=31.3953488372093, Blast_Score=164, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 42307; Mature: 42307

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVDLSLLLPGPLCSQHLADMGAEVIKVENPRAYDGSRAMFKGKTGYPALFMMLNRNKK
CEEEEEEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCEEEEEEECCCE
AITLNLKREQAKEILFKLLEDADILLEGFRPDGMDKMGIGYDVLKEKFPRLIYCGISGYG
EEEEEECHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCC
TSGKYVDFAGHDLNYLAISGVLDQTGNPPRPAGFQMADVGGGTLTALSAILAALYYREKT
CCCCEEEECCCCCCEEEEECHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCC
GKGQKIDISMTDASLQFIALYGGILSASGVSPEAGNDILSGKLPNYNVYETKEGRYVALG
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEH
ALEDMFFQTFLRAAGMDTLTKDHPMTEENFAIIKQKLTDFFKSKTFADLQPIFDNTDACL
HHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
SPILNMKEVSEDANMKERGMILERNHPKYGPILQFGSPFHFSETPFVYRNDPPEHGEHTE
HHHHCHHHHHCCCCHHHCCEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCHHH
DILTQLGFSKDQISGFKKDRVV
HHHHHHCCCHHHHCCCHHCCCC
>Mature Secondary Structure
MKVVDLSLLLPGPLCSQHLADMGAEVIKVENPRAYDGSRAMFKGKTGYPALFMMLNRNKK
CEEEEEEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCEEEEEEECCCE
AITLNLKREQAKEILFKLLEDADILLEGFRPDGMDKMGIGYDVLKEKFPRLIYCGISGYG
EEEEEECHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCC
TSGKYVDFAGHDLNYLAISGVLDQTGNPPRPAGFQMADVGGGTLTALSAILAALYYREKT
CCCCEEEECCCCCCEEEEECHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCC
GKGQKIDISMTDASLQFIALYGGILSASGVSPEAGNDILSGKLPNYNVYETKEGRYVALG
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEH
ALEDMFFQTFLRAAGMDTLTKDHPMTEENFAIIKQKLTDFFKSKTFADLQPIFDNTDACL
HHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
SPILNMKEVSEDANMKERGMILERNHPKYGPILQFGSPFHFSETPFVYRNDPPEHGEHTE
HHHHCHHHHHCCCCHHHCCEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCHHH
DILTQLGFSKDQISGFKKDRVV
HHHHHHCCCHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA