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The map label for this gene is yheS [H]

Identifier: 183222089

GI number: 183222089

Start: 2823305

End: 2824801

Strand: Reverse

Name: yheS [H]

Synonym: LEPBI_I2731

Alternate gene names: 183222089

Gene position: 2824801-2823305 (Counterclockwise)

Preceding gene: 183222091

Following gene: 183222088

Centisome position: 78.47

GC content: 41.42

Gene sequence:

>1497_bases
ATGATCAAAATATCTGGCTTAAACAAACAATTCAACGGCAATGTTTTATTCGATGACTTACAATTCAGTGTCAACCGTGG
AGAAAGAGTGGGACTTGTGGGTCGTAATGGCCACGGAAAGTCTACTCTTGTTCAAATCATTTTAGGAAAAACAGAAGCTG
ATTCTGGAAACATCACCATCCCGAAAGGTTACCGCATTGGCCACTTAGAACAACACTTAGTTTTTACGAAACCAACAGTT
CTTGAAGAATGTGCCCTTGGTTTGCCTGAAGGGGATGAATACGAAACTTGGAAAGTGGAGCGGATTTTATTTGGACTTGG
ATTTTCAGAAGGGGATATGGAAAGAAGCCCCAATGAATTTTCTGGTGGTTACCAAATTCGGATGAACTTGGCAAAACTCC
TTGTGTCTGCTCCAGACATGCTCATCTTAGATGAACCAAACAACTATTTGGATATTGTCACCATACGTTGGTTAGAGGAG
TTCCTTCGTGAATGGGAAGGGGAAATCATCCTCATCACACACGATAGAAGTTTTATGGACAGTGTTGTGACCCATACAGT
CGCCATCCACCGTACCAAAGCCATCAAAGTACAAGGTGATACAGAAAAATTATACACCCAAATCAACCAGGCAGAAGAAA
TTTACGAAAAAACGAGACTCAACGAAGCCAAAAAACGAAAACAAGAAGAAATGTTCATCGCCAAGTTCAAAGCCAAGGCT
AGTTTTGCGAGCCGTACCCAATCCCGTGTGAAAAAATTAGAAAAACAAGGTGAGATGAAAGCTCTGGATTCCATCGAAGA
TATGGAATTGTACTTTAACAGTGCCCCATTCTCCGCCAATCAAATGTTAAGCGTAGAAGATGTTTCTTTTTCCTATGATG
GGAAGTCTCCTTTTTTGTTTGAAAATTTTTCTATCAGTGTCGGGCCAGAAGATCGGATTTGTATCATCGGAAAAAACGGA
AAAGGAAAATCTACCCTTCTCAAACTCATTGCAGGGGAACTCTCACCTGTTTCTGGTGCCGTAAAAAAACACCCGATCTT
AAAAGAAGGATACTTCGGACAAACAAACAAACTGAATATGACAGAAGGGAATACAGTCGTGCAGGAAATTATGAGTGCCG
ATCCTAATTGTTCGGAAGGGAAAGCTCGTAATATTGCTGGTGGTTTGATGTTTTCAGAAGACCTTGCCTTAAAAAAAGTG
AAGGTCCTTTCGGGGGGAGAAAAGAGCCGGGTATTACTTGGTAAAATTTTAGTGACCCCTTGCCACTTACTTTACTTAGA
TGAACCGACAAACCACTTAGATATGCAGTCCTGCGACTCTCTGATTGAAGCCATCGATAATTTTGATGGATCTGTGATTA
TGGTCACCCACAACGAAATGCACTTGCGTGCTGTGGCGACAAAACTAATTGTATTCGATGATGACCGAGTTTTTGTCTAT
GATGGTGGTTATGACGACTTCCTCTCAGACATTGGCTGGAAGGATGAAACCGTTTGA

Upstream 100 bases:

>100_bases
TAAAACCGTAAAAAACCCACAATTTTTCATTTCTTTCTACTCGTCCTTTCGGCTAGATTCTGCATCTTGGTTTTATACCT
ACTCCCCCTTCGGAATTTAT

Downstream 100 bases:

>100_bases
AACCAATCCTAACCGTAAAACAAGTTTCCAAGTCCTATGAAAATGGATTCCAAGCATTAAAAACTGTGAATTGGGTAGTG
GCTGATGGGGAAATCCACGC

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MIKISGLNKQFNGNVLFDDLQFSVNRGERVGLVGRNGHGKSTLVQIILGKTEADSGNITIPKGYRIGHLEQHLVFTKPTV
LEECALGLPEGDEYETWKVERILFGLGFSEGDMERSPNEFSGGYQIRMNLAKLLVSAPDMLILDEPNNYLDIVTIRWLEE
FLREWEGEIILITHDRSFMDSVVTHTVAIHRTKAIKVQGDTEKLYTQINQAEEIYEKTRLNEAKKRKQEEMFIAKFKAKA
SFASRTQSRVKKLEKQGEMKALDSIEDMELYFNSAPFSANQMLSVEDVSFSYDGKSPFLFENFSISVGPEDRICIIGKNG
KGKSTLLKLIAGELSPVSGAVKKHPILKEGYFGQTNKLNMTEGNTVVQEIMSADPNCSEGKARNIAGGLMFSEDLALKKV
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDNFDGSVIMVTHNEMHLRAVATKLIVFDDDRVFVY
DGGYDDFLSDIGWKDETV

Sequences:

>Translated_498_residues
MIKISGLNKQFNGNVLFDDLQFSVNRGERVGLVGRNGHGKSTLVQIILGKTEADSGNITIPKGYRIGHLEQHLVFTKPTV
LEECALGLPEGDEYETWKVERILFGLGFSEGDMERSPNEFSGGYQIRMNLAKLLVSAPDMLILDEPNNYLDIVTIRWLEE
FLREWEGEIILITHDRSFMDSVVTHTVAIHRTKAIKVQGDTEKLYTQINQAEEIYEKTRLNEAKKRKQEEMFIAKFKAKA
SFASRTQSRVKKLEKQGEMKALDSIEDMELYFNSAPFSANQMLSVEDVSFSYDGKSPFLFENFSISVGPEDRICIIGKNG
KGKSTLLKLIAGELSPVSGAVKKHPILKEGYFGQTNKLNMTEGNTVVQEIMSADPNCSEGKARNIAGGLMFSEDLALKKV
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDNFDGSVIMVTHNEMHLRAVATKLIVFDDDRVFVY
DGGYDDFLSDIGWKDETV
>Mature_498_residues
MIKISGLNKQFNGNVLFDDLQFSVNRGERVGLVGRNGHGKSTLVQIILGKTEADSGNITIPKGYRIGHLEQHLVFTKPTV
LEECALGLPEGDEYETWKVERILFGLGFSEGDMERSPNEFSGGYQIRMNLAKLLVSAPDMLILDEPNNYLDIVTIRWLEE
FLREWEGEIILITHDRSFMDSVVTHTVAIHRTKAIKVQGDTEKLYTQINQAEEIYEKTRLNEAKKRKQEEMFIAKFKAKA
SFASRTQSRVKKLEKQGEMKALDSIEDMELYFNSAPFSANQMLSVEDVSFSYDGKSPFLFENFSISVGPEDRICIIGKNG
KGKSTLLKLIAGELSPVSGAVKKHPILKEGYFGQTNKLNMTEGNTVVQEIMSADPNCSEGKARNIAGGLMFSEDLALKKV
KVLSGGEKSRVLLGKILVTPCHLLYLDEPTNHLDMQSCDSLIEAIDNFDGSVIMVTHNEMHLRAVATKLIVFDDDRVFVY
DGGYDDFLSDIGWKDETV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=33.0812854442344, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI10947137, Length=517, Percent_Identity=30.3675048355899, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI27881506, Length=517, Percent_Identity=30.3675048355899, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=29.182156133829, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=29.182156133829, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1789751, Length=529, Percent_Identity=32.8922495274102, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1787041, Length=535, Percent_Identity=33.0841121495327, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1787182, Length=540, Percent_Identity=31.4814814814815, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI2367384, Length=519, Percent_Identity=27.7456647398844, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI48995001, Length=521, Percent_Identity=24.3761996161228, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=228, Percent_Identity=26.7543859649123, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788165, Length=202, Percent_Identity=31.1881188118812, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=24.6636771300448, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=210, Percent_Identity=28.0952380952381, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788225, Length=241, Percent_Identity=28.2157676348548, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786253, Length=230, Percent_Identity=30, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787758, Length=204, Percent_Identity=27.9411764705882, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081709, Length=223, Percent_Identity=25.1121076233184, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788450, Length=227, Percent_Identity=27.3127753303965, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787500, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787029, Length=215, Percent_Identity=24.6511627906977, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=231, Percent_Identity=27.7056277056277, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787164, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=534, Percent_Identity=29.4007490636704, Blast_Score=244, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17559834, Length=547, Percent_Identity=29.7989031078611, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17555318, Length=520, Percent_Identity=28.2692307692308, Blast_Score=218, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=30.3939962476548, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6320874, Length=519, Percent_Identity=28.5163776493256, Blast_Score=206, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6325030, Length=349, Percent_Identity=28.6532951289398, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=346, Percent_Identity=24.5664739884393, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323278, Length=350, Percent_Identity=24.5714285714286, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324985, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24666836, Length=533, Percent_Identity=33.3958724202627, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24642252, Length=536, Percent_Identity=30.0373134328358, Blast_Score=235, Evalue=7e-62,
Organism=Drosophila melanogaster, GI18859989, Length=536, Percent_Identity=30.0373134328358, Blast_Score=235, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=31.8949343339587, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28574259, Length=178, Percent_Identity=29.7752808988764, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 55831; Mature: 55831

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKISGLNKQFNGNVLFDDLQFSVNRGERVGLVGRNGHGKSTLVQIILGKTEADSGNITI
CEEECCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCHHHEEEEEECCCCCCCCCEEE
PKGYRIGHLEQHLVFTKPTVLEECALGLPEGDEYETWKVERILFGLGFSEGDMERSPNEF
CCCCEECCCHHCEEECCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
SGGYQIRMNLAKLLVSAPDMLILDEPNNYLDIVTIRWLEEFLREWEGEIILITHDRSFMD
CCCEEEEEHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCCCEEEEECCHHHHH
SVVTHTVAIHRTKAIKVQGDTEKLYTQINQAEEIYEKTRLNEAKKRKQEEMFIAKFKAKA
HHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFASRTQSRVKKLEKQGEMKALDSIEDMELYFNSAPFSANQMLSVEDVSFSYDGKSPFLF
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHEEECCCCCCCCCEEEEEECEEEECCCCCEEE
ENFSISVGPEDRICIIGKNGKGKSTLLKLIAGELSPVSGAVKKHPILKEGYFGQTNKLNM
ECEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCEEEC
TEGNTVVQEIMSADPNCSEGKARNIAGGLMFSEDLALKKVKVLSGGEKSRVLLGKILVTP
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHEEEEECCCCCCCEEEHHHHHCC
CHLLYLDEPTNHLDMQSCDSLIEAIDNFDGSVIMVTHNEMHLRAVATKLIVFDDDRVFVY
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEEEECCEEEEE
DGGYDDFLSDIGWKDETV
ECCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIKISGLNKQFNGNVLFDDLQFSVNRGERVGLVGRNGHGKSTLVQIILGKTEADSGNITI
CEEECCCCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCHHHEEEEEECCCCCCCCCEEE
PKGYRIGHLEQHLVFTKPTVLEECALGLPEGDEYETWKVERILFGLGFSEGDMERSPNEF
CCCCEECCCHHCEEECCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
SGGYQIRMNLAKLLVSAPDMLILDEPNNYLDIVTIRWLEEFLREWEGEIILITHDRSFMD
CCCEEEEEHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCCCEEEEECCHHHHH
SVVTHTVAIHRTKAIKVQGDTEKLYTQINQAEEIYEKTRLNEAKKRKQEEMFIAKFKAKA
HHHHHHHEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFASRTQSRVKKLEKQGEMKALDSIEDMELYFNSAPFSANQMLSVEDVSFSYDGKSPFLF
HHHHHHHHHHHHHHHCCCHHHHCCHHHHHEEECCCCCCCCCEEEEEECEEEECCCCCEEE
ENFSISVGPEDRICIIGKNGKGKSTLLKLIAGELSPVSGAVKKHPILKEGYFGQTNKLNM
ECEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCEEEC
TEGNTVVQEIMSADPNCSEGKARNIAGGLMFSEDLALKKVKVLSGGEKSRVLLGKILVTP
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHEEEEECCCCCCCEEEHHHHHCC
CHLLYLDEPTNHLDMQSCDSLIEAIDNFDGSVIMVTHNEMHLRAVATKLIVFDDDRVFVY
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEEEECCEEEEE
DGGYDDFLSDIGWKDETV
ECCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]