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The map label for this gene is lolC [H]

Identifier: 183221930

GI number: 183221930

Start: 2656003

End: 2657256

Strand: Reverse

Name: lolC [H]

Synonym: LEPBI_I2569

Alternate gene names: 183221930

Gene position: 2657256-2656003 (Counterclockwise)

Preceding gene: 183221931

Following gene: 183221929

Centisome position: 73.82

GC content: 40.83

Gene sequence:

>1254_bases
ATGTTATTCCTTGCGATTCGCCAAATTTTATCCAGACCACAACAGTCTATTTTGACTTTGATTGGGATCATCCTTGGGAC
AGCTGGATACATTGTTTTTTCAGGGATTATGCTTGGGTTCCAAGCCGTGATCACAGACCAATTGGTCAATTCAGATGGAC
AAATTAAAATTTCACCTAAAGATGAACTGATCACCGAACGTACATTTGATGACGTTTTTTTTCAGGGAAAAGAAGTTCGT
TGGCTTTCTCCCCCATCGGGAAGAACCGATAATTCAAGGCTAACCAATGTTCTTGGGTGGATGGATAAATTATCCAATGA
CCAAAGGGTGGTTTCCTTTGCCCCCCAACTCACAAAAGAAGTGATTTTTGTGAATGGGAAAGCAACTGCTCCCGCAAGAT
TTGTGGGTGTGGATCCAAACATCCAACCGAAAGTTACCAACCTAAGCGATTACATTGTCGAAGGGAAGTTGGTTGATTTA
TCTAAAGGGACATCCCTTGCCATAGCGGGAGAAGGGGTTCTCAATAAATTGGGAGCAAAGATTGATGACACAATCTTTGT
TTATATCCCAGGCACAGATCTTGTACCCATCAAAATTGTTGGCATTTTAAGTACGGGGAACCGTCTTGTTGATGAGGTCA
CAGTGTATTCGTCCTTATCCACAGTGCAAAGTATCACCAAATCAAGTGGTGAGATCTCTCAAATCATTGTCAAAATTAAG
GATATTCGTACGGCAAAAGAAATTGCTGAGGACTGGCGATACTTTAGCAAAGATAAGGTGGAAAGTTGGGACGAAGTGAA
TGCGAGTATCTTACAAGTTTTTCGGACACAAGATATTGTAAGAAACTCAACCACTTTCACCATCATCTTAGTGGTTGCCT
TTGGAATTTACAATATCCTAAATATGGTAGTAAACCAAAAGAAAAAGGAAGTGGCTATCTTACGTTCGATTGGATTTGAT
GAAAAGGATACAATCCAACTCTTTATTTTCCAAGGATTATTTTTAGGAACACTTGGTGCCATCATTGGCATATTCGTGGG
AATCCTCGGTTGTTATTACATTGATGGAATTCCCATTGGAGATCCAAAACAAAATTCAAAAGCCTTGATGAAAACCATGA
TGATCTCCTGGGATATGATGATTTATGTAAAAGGGTTTTCCATTGCTGTCCTCAGTGCATCCATTGCGAGTTATATCCCG
GCTCGAATGGCAAGCCGACTGTCGCCCGTCGATATCATTCGAGGTGCCACATGA

Upstream 100 bases:

>100_bases
AGAAAAAATGGAAATTCGAATTGGTGCCATCAATTCAGAGTTTGGTGAACTGATCCAAGGTGATTTACTTGAGGGTGATG
AAGTACTGGTAAAAAATTAA

Downstream 100 bases:

>100_bases
GTTTTGGAATCGAAGCCGATCGTATCTTTAAATCATTTGGGGAACCACCCCAAGTGGTTTTACAAGATGTATCCTTAAAC
ATCAAAGAAGGGAACTTTGT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLFLAIRQILSRPQQSILTLIGIILGTAGYIVFSGIMLGFQAVITDQLVNSDGQIKISPKDELITERTFDDVFFQGKEVR
WLSPPSGRTDNSRLTNVLGWMDKLSNDQRVVSFAPQLTKEVIFVNGKATAPARFVGVDPNIQPKVTNLSDYIVEGKLVDL
SKGTSLAIAGEGVLNKLGAKIDDTIFVYIPGTDLVPIKIVGILSTGNRLVDEVTVYSSLSTVQSITKSSGEISQIIVKIK
DIRTAKEIAEDWRYFSKDKVESWDEVNASILQVFRTQDIVRNSTTFTIILVVAFGIYNILNMVVNQKKKEVAILRSIGFD
EKDTIQLFIFQGLFLGTLGAIIGIFVGILGCYYIDGIPIGDPKQNSKALMKTMMISWDMMIYVKGFSIAVLSASIASYIP
ARMASRLSPVDIIRGAT

Sequences:

>Translated_417_residues
MLFLAIRQILSRPQQSILTLIGIILGTAGYIVFSGIMLGFQAVITDQLVNSDGQIKISPKDELITERTFDDVFFQGKEVR
WLSPPSGRTDNSRLTNVLGWMDKLSNDQRVVSFAPQLTKEVIFVNGKATAPARFVGVDPNIQPKVTNLSDYIVEGKLVDL
SKGTSLAIAGEGVLNKLGAKIDDTIFVYIPGTDLVPIKIVGILSTGNRLVDEVTVYSSLSTVQSITKSSGEISQIIVKIK
DIRTAKEIAEDWRYFSKDKVESWDEVNASILQVFRTQDIVRNSTTFTIILVVAFGIYNILNMVVNQKKKEVAILRSIGFD
EKDTIQLFIFQGLFLGTLGAIIGIFVGILGCYYIDGIPIGDPKQNSKALMKTMMISWDMMIYVKGFSIAVLSASIASYIP
ARMASRLSPVDIIRGAT
>Mature_417_residues
MLFLAIRQILSRPQQSILTLIGIILGTAGYIVFSGIMLGFQAVITDQLVNSDGQIKISPKDELITERTFDDVFFQGKEVR
WLSPPSGRTDNSRLTNVLGWMDKLSNDQRVVSFAPQLTKEVIFVNGKATAPARFVGVDPNIQPKVTNLSDYIVEGKLVDL
SKGTSLAIAGEGVLNKLGAKIDDTIFVYIPGTDLVPIKIVGILSTGNRLVDEVTVYSSLSTVQSITKSSGEISQIIVKIK
DIRTAKEIAEDWRYFSKDKVESWDEVNASILQVFRTQDIVRNSTTFTIILVVAFGIYNILNMVVNQKKKEVAILRSIGFD
EKDTIQLFIFQGLFLGTLGAIIGIFVGILGCYYIDGIPIGDPKQNSKALMKTMMISWDMMIYVKGFSIAVLSASIASYIP
ARMASRLSPVDIIRGAT

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=351, Percent_Identity=21.3675213675214, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45894; Mature: 45894

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLAIRQILSRPQQSILTLIGIILGTAGYIVFSGIMLGFQAVITDQLVNSDGQIKISPK
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
DELITERTFDDVFFQGKEVRWLSPPSGRTDNSRLTNVLGWMDKLSNDQRVVSFAPQLTKE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHCEE
VIFVNGKATAPARFVGVDPNIQPKVTNLSDYIVEGKLVDLSKGTSLAIAGEGVLNKLGAK
EEEECCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEECCHHHHHHCCC
IDDTIFVYIPGTDLVPIKIVGILSTGNRLVDEVTVYSSLSTVQSITKSSGEISQIIVKIK
CCCEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DIRTAKEIAEDWRYFSKDKVESWDEVNASILQVFRTQDIVRNSTTFTIILVVAFGIYNIL
HHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NMVVNQKKKEVAILRSIGFDEKDTIQLFIFQGLFLGTLGAIIGIFVGILGCYYIDGIPIG
HHHHCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DPKQNSKALMKTMMISWDMMIYVKGFSIAVLSASIASYIPARMASRLSPVDIIRGAT
CCCCHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MLFLAIRQILSRPQQSILTLIGIILGTAGYIVFSGIMLGFQAVITDQLVNSDGQIKISPK
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
DELITERTFDDVFFQGKEVRWLSPPSGRTDNSRLTNVLGWMDKLSNDQRVVSFAPQLTKE
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHCEE
VIFVNGKATAPARFVGVDPNIQPKVTNLSDYIVEGKLVDLSKGTSLAIAGEGVLNKLGAK
EEEECCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCEEEEECCHHHHHHCCC
IDDTIFVYIPGTDLVPIKIVGILSTGNRLVDEVTVYSSLSTVQSITKSSGEISQIIVKIK
CCCEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DIRTAKEIAEDWRYFSKDKVESWDEVNASILQVFRTQDIVRNSTTFTIILVVAFGIYNIL
HHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NMVVNQKKKEVAILRSIGFDEKDTIQLFIFQGLFLGTLGAIIGIFVGILGCYYIDGIPIG
HHHHCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DPKQNSKALMKTMMISWDMMIYVKGFSIAVLSASIASYIPARMASRLSPVDIIRGAT
CCCCHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]