Click here to switch to the map view.

The map label for this gene is melR [C]

Identifier: 183221870

GI number: 183221870

Start: 2588753

End: 2590012

Strand: Reverse

Name: melR [C]

Synonym: LEPBI_I2504

Alternate gene names: 183221870

Gene position: 2590012-2588753 (Counterclockwise)

Preceding gene: 183221871

Following gene: 183221869

Centisome position: 71.95

GC content: 34.44

Gene sequence:

>1260_bases
GTGCAGTGGACAGGATCTGGTCGCAAATGGACTACCGAAGGTGATTTAGTTCCTAAGAGAAAACATTTATTTCCAAATCA
TCCTTTTCCTATCTTCTCCATTGATACGAAATCATTAAAAGACCATCCCACGTTTTATTTAGAAGCAAAGACAGTTTCGA
ATTTTTTATTCGCGCCAAAACTTTTGACAAAGGATGGAATCTTACAATCAGTAATGGAAACGCGAGATCATTTTTTAGTT
TTCTTTAGTGTGTTACTCATTGTGTTTATTTTGAATCTCAGTATTTATTTTAATACTCGGAACACTAGTTTTTTGTATTA
TTGTTTTTATATTTTGTGTTCTGGTTTTTACCAAATCAGTTATACAGGATATGGAAAAATTTATCTTTGGTCCGATTGGA
TTCGTTGGAATGACCGTAGTCTTGTGTTTTTTGGATCGATTGCCTTGTGGAGTGTGATCCTTTTTTCGAATTCATTTTTG
TTACTTTCCAAACGAATGCCAAAATTGAATCGAGTGATGATTGTCTTTTCGGTTTTGGTTGTTTCCAATGCCATCCTAAG
TCTTTTTTGGAAACACATTATCTTTGACCAAACCATTCATTTTTTAGCGATTTTTGTCTCTTTTACGCTCATGGGTGCAG
GTATTTATGTTTTTTTCCAAAAATACCAAATGGCAAAATACTATATCGTCGCATGGTTTTGTTTGCTTCTTGCCATCATC
TCTTTCAATTTGTATGCGTTTAACATTTTACCAGATCATTTTATTTTACGAAATGCCATTCAATACGGAAACTTTTTTGA
AATTATCTTATTCCAGTTTGCACTTTTTGCAAGGATTCAGGAAACAAAAGAAGTTCCAATCTTTTTTGCCACTGTTTCGA
AACCGCGACTCTCAGAACAAAGGATAGCAAATTTAAACTCAGATCAAATTTTAAAGGACATTGATTCTGCCTTAGTTACT
GAAAAATTATATTTGGATGAAGATTTAAATCTACAAAATGTTGCTTCAAAATTCCGATTGAGGACGGATCAGTTGTCTGC
CATCATCAATCAAAAACAGGGCATCAATTTTAACCAGTGGATCAATGGGTATCGAATTCGGGAAGCCTGTCAGTTGATGG
AAAAAGATCCTGAAAAAAATATACTCACCATTGCCTTTGCCGTTGGGTTTAATTCCAAGTCAGCCTTTAATGATGCCTTC
AAACGAGTGATGGGAGAAACTCCAACGGAATACAGAAAACGATTTTTACAATTGGTTTGA

Upstream 100 bases:

>100_bases
TACAGAGCCAATCCTTTTTCGAGTCGAATGGTTGGACAAAGAAATTCCAGACGAATTGTATTTGGAAAATCAAGTTGCTT
ACTTCGATTCGATTGAACTT

Downstream 100 bases:

>100_bases
GAAGTGATTCTTTTTGGATGAATTCATTTCAAACGAAAAATTGTCTCTAAATTATCCAGTATGTTGCAGAGTGGCGAAAG
CTCATGAAATTGAATTTACC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator AraC Family; Diguanylate Cyclase; Sensor Histidine Kinase; Transcriptional Regulator; Helix-Turn-Helix Domain-Containing Protein; Adenylate/Guanylate Cyclase; Transcriptional Regulator Arac Family; Response Regulator; Helix-Turn-Helix- Domain Containing Protein AraC Type; Response Regulator Receiver Protein; Helix-TurN-Helix- Domain Containing Protein Arac Type; Response Regulator Receiver Domain Protein; Response Regulator Receiver Domain-Containing Protein; Histidine Kinase; Two-Component Response Regulator; PAS Sensor Protein; RhaRS Operon Positive Regulator; Phosphoserine Phosphatase RsbP; AraC/XylS Family Transcriptional Regulator; Transcriptional Regulator AraC/XylS Family; Regulatory Helix-Turn-Helix Protein AraC Family; AraC Family Transcription Regulator; Lost Adherence Sensor LadS; Multi-Sensor Signal Transduction Multi-Kinase; Transcriptional Regulator AraC Family Domain Protein; Signal Protein; Two-Component Sensor; Two-Component System Sensor Kinase; Helix-Turn-Helix AraC Type; Diverse 7TM Receptor Transmembrane Region; Transcriptional Regulator Protein AraC Family; Signal Transduction Protein; Transcriptional Regulator Protein; Transcription Regulator; Integral Membrane Sensor Hybrid Histidine Kinase; Sensory Transduction Histidine Kinase; Transmembrane Signal Transduction Protein; Sensor Protein For Response Regulator AtoC; Periplasmic Sensor Hybrid Histidine Kinase; Diverse 7tm Receptor Transmembrane Region; Sensor Histidine Kinase/Response Regulator; ATPase Histidine Kinase- DNA Gyrase B- And

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MQWTGSGRKWTTEGDLVPKRKHLFPNHPFPIFSIDTKSLKDHPTFYLEAKTVSNFLFAPKLLTKDGILQSVMETRDHFLV
FFSVLLIVFILNLSIYFNTRNTSFLYYCFYILCSGFYQISYTGYGKIYLWSDWIRWNDRSLVFFGSIALWSVILFSNSFL
LLSKRMPKLNRVMIVFSVLVVSNAILSLFWKHIIFDQTIHFLAIFVSFTLMGAGIYVFFQKYQMAKYYIVAWFCLLLAII
SFNLYAFNILPDHFILRNAIQYGNFFEIILFQFALFARIQETKEVPIFFATVSKPRLSEQRIANLNSDQILKDIDSALVT
EKLYLDEDLNLQNVASKFRLRTDQLSAIINQKQGINFNQWINGYRIREACQLMEKDPEKNILTIAFAVGFNSKSAFNDAF
KRVMGETPTEYRKRFLQLV

Sequences:

>Translated_419_residues
MQWTGSGRKWTTEGDLVPKRKHLFPNHPFPIFSIDTKSLKDHPTFYLEAKTVSNFLFAPKLLTKDGILQSVMETRDHFLV
FFSVLLIVFILNLSIYFNTRNTSFLYYCFYILCSGFYQISYTGYGKIYLWSDWIRWNDRSLVFFGSIALWSVILFSNSFL
LLSKRMPKLNRVMIVFSVLVVSNAILSLFWKHIIFDQTIHFLAIFVSFTLMGAGIYVFFQKYQMAKYYIVAWFCLLLAII
SFNLYAFNILPDHFILRNAIQYGNFFEIILFQFALFARIQETKEVPIFFATVSKPRLSEQRIANLNSDQILKDIDSALVT
EKLYLDEDLNLQNVASKFRLRTDQLSAIINQKQGINFNQWINGYRIREACQLMEKDPEKNILTIAFAVGFNSKSAFNDAF
KRVMGETPTEYRKRFLQLV
>Mature_419_residues
MQWTGSGRKWTTEGDLVPKRKHLFPNHPFPIFSIDTKSLKDHPTFYLEAKTVSNFLFAPKLLTKDGILQSVMETRDHFLV
FFSVLLIVFILNLSIYFNTRNTSFLYYCFYILCSGFYQISYTGYGKIYLWSDWIRWNDRSLVFFGSIALWSVILFSNSFL
LLSKRMPKLNRVMIVFSVLVVSNAILSLFWKHIIFDQTIHFLAIFVSFTLMGAGIYVFFQKYQMAKYYIVAWFCLLLAII
SFNLYAFNILPDHFILRNAIQYGNFFEIILFQFALFARIQETKEVPIFFATVSKPRLSEQRIANLNSDQILKDIDSALVT
EKLYLDEDLNLQNVASKFRLRTDQLSAIINQKQGINFNQWINGYRIREACQLMEKDPEKNILTIAFAVGFNSKSAFNDAF
KRVMGETPTEYRKRFLQLV

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49152; Mature: 49152

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWTGSGRKWTTEGDLVPKRKHLFPNHPFPIFSIDTKSLKDHPTFYLEAKTVSNFLFAPK
CCCCCCCCEECCCCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHCCH
LLTKDGILQSVMETRDHFLVFFSVLLIVFILNLSIYFNTRNTSFLYYCFYILCSGFYQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCCEEEE
YTGYGKIYLWSDWIRWNDRSLVFFGSIALWSVILFSNSFLLLSKRMPKLNRVMIVFSVLV
EECCEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCEEEHHCCCHHHHHHHHHHHHH
VSNAILSLFWKHIIFDQTIHFLAIFVSFTLMGAGIYVFFQKYQMAKYYIVAWFCLLLAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFNLYAFNILPDHFILRNAIQYGNFFEIILFQFALFARIQETKEVPIFFATVSKPRLSEQ
HCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
RIANLNSDQILKDIDSALVTEKLYLDEDLNLQNVASKFRLRTDQLSAIINQKQGINFNQW
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
INGYRIREACQLMEKDPEKNILTIAFAVGFNSKSAFNDAFKRVMGETPTEYRKRFLQLV
HCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQWTGSGRKWTTEGDLVPKRKHLFPNHPFPIFSIDTKSLKDHPTFYLEAKTVSNFLFAPK
CCCCCCCCEECCCCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHCCH
LLTKDGILQSVMETRDHFLVFFSVLLIVFILNLSIYFNTRNTSFLYYCFYILCSGFYQIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHCCCEEEE
YTGYGKIYLWSDWIRWNDRSLVFFGSIALWSVILFSNSFLLLSKRMPKLNRVMIVFSVLV
EECCEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCEEEHHCCCHHHHHHHHHHHHH
VSNAILSLFWKHIIFDQTIHFLAIFVSFTLMGAGIYVFFQKYQMAKYYIVAWFCLLLAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFNLYAFNILPDHFILRNAIQYGNFFEIILFQFALFARIQETKEVPIFFATVSKPRLSEQ
HCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
RIANLNSDQILKDIDSALVTEKLYLDEDLNLQNVASKFRLRTDQLSAIINQKQGINFNQW
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
INGYRIREACQLMEKDPEKNILTIAFAVGFNSKSAFNDAFKRVMGETPTEYRKRFLQLV
HCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA