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The map label for this gene is aroB [H]

Identifier: 183221838

GI number: 183221838

Start: 2551439

End: 2552602

Strand: Reverse

Name: aroB [H]

Synonym: LEPBI_I2469

Alternate gene names: 183221838

Gene position: 2552602-2551439 (Counterclockwise)

Preceding gene: 183221839

Following gene: 183221837

Centisome position: 70.91

GC content: 35.57

Gene sequence:

>1164_bases
ATGAAAGAGAATCGTTCGAAAAACATTCGGTCTGAATTCCAAGTTACCTATGAGTATGATGTTTTTTTTACCAAAGAATT
ATTTTCATTGGAAAACATACTACTCAGTGAATTTTTCCAATCTAAAAAAACTGACAAAATGAAAAAGAAGGTTTTGGTTG
TGATTGACCAAGGGTTATTCAACTTTCACAACAAAATTTTAGAATCCATCCCTCAATATTTTCAATCAAATGTAGAATCT
GTACAATTGATTGAAGATCTCATTATTCTTCCAGGTGGAGAAACATCAAAAAATGATTCAAATGGTTGGGAATTAGTTGT
GTCAGCTATCAACCAATATGGAATTGATCGGCATTCTTATCTTATGGTGATCGGTGGTGGTGCTATTTTAGATATGGTTG
GTTATGCGGCAGCTGTTGCACATCGAGGCATTCGTTTGATTCGAATCCCAACAACTGTACTTTCTCAAAATGATTCTGGT
GTTGGTGTTAAAAATAGTATTAATTATTTTGGAAAAAAAAATTTTCTTGGAACCTTTGCACCTCCTGTCGCTGTATTCAA
TGATTCTTCGTTTTTAGTCTCTTTAGAAGATAGGGATTGGCGTTCTGGTATGGCAGAAGCAGTGAAAGTTTCTCTAATCA
AAAACAAAGTTTTTTTTGAATGGATGGAATCTCATGTTTCTGAACTCACCCATCGGGACCTGACTACGATGGAACATTTA
GTTTATGAATGTGCAAGGCTTCATATGGAACACATTCAAAATGGAGATCCTTTCGAGTTTGGTTCTTCTCGCCCACTTGA
TTTTGGACATTGGTTTGCTCATAAATTAGAATACTTGGCAAATTTTTCCATCCGTCATGGCGAAGCGGTGGCAATCGGAA
TGGCTTTGGATTCCATTTATTCGTATCTTTCTGGTTTTTTGCAAGAATCCGAGTTGAATCGAATTTTAAATTTATTAAGA
GATCTTGGGTTTCAATTTAACCATCCCGTGCTTCTCAAAAACGGAAAAGAGAATTTGGAACTTGCTCTAAAAGAATTCCA
AGAACACTTAGGCGGAAAACTCACCTTGCTAATGTTAGAAGGAATTGGTTTTCCAAAGGAAGTTTATACAATTCATTTAT
CTTTGTTAGAATCTGCATACGATCGTTTGGTTGGATGGAAGTGA

Upstream 100 bases:

>100_bases
TTGCAGCAGCCTTTGGGATGGTGCCATTGGCCTTTCTCATTCTAAGTTTGTTACCAATCTCTTTCTCCATCTCCAAATAT
TTTGCAGTGACCTAAATACG

Downstream 100 bases:

>100_bases
AGACTAAATATGGTAACCTAACATATTGTTCGAATATCCATCCAGGAGAATCTTGGAAGGATCACTTCCTTGAATTAAAA
ACCTATCTACCTAAAATTAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKENRSKNIRSEFQVTYEYDVFFTKELFSLENILLSEFFQSKKTDKMKKKVLVVIDQGLFNFHNKILESIPQYFQSNVES
VQLIEDLIILPGGETSKNDSNGWELVVSAINQYGIDRHSYLMVIGGGAILDMVGYAAAVAHRGIRLIRIPTTVLSQNDSG
VGVKNSINYFGKKNFLGTFAPPVAVFNDSSFLVSLEDRDWRSGMAEAVKVSLIKNKVFFEWMESHVSELTHRDLTTMEHL
VYECARLHMEHIQNGDPFEFGSSRPLDFGHWFAHKLEYLANFSIRHGEAVAIGMALDSIYSYLSGFLQESELNRILNLLR
DLGFQFNHPVLLKNGKENLELALKEFQEHLGGKLTLLMLEGIGFPKEVYTIHLSLLESAYDRLVGWK

Sequences:

>Translated_387_residues
MKENRSKNIRSEFQVTYEYDVFFTKELFSLENILLSEFFQSKKTDKMKKKVLVVIDQGLFNFHNKILESIPQYFQSNVES
VQLIEDLIILPGGETSKNDSNGWELVVSAINQYGIDRHSYLMVIGGGAILDMVGYAAAVAHRGIRLIRIPTTVLSQNDSG
VGVKNSINYFGKKNFLGTFAPPVAVFNDSSFLVSLEDRDWRSGMAEAVKVSLIKNKVFFEWMESHVSELTHRDLTTMEHL
VYECARLHMEHIQNGDPFEFGSSRPLDFGHWFAHKLEYLANFSIRHGEAVAIGMALDSIYSYLSGFLQESELNRILNLLR
DLGFQFNHPVLLKNGKENLELALKEFQEHLGGKLTLLMLEGIGFPKEVYTIHLSLLESAYDRLVGWK
>Mature_387_residues
MKENRSKNIRSEFQVTYEYDVFFTKELFSLENILLSEFFQSKKTDKMKKKVLVVIDQGLFNFHNKILESIPQYFQSNVES
VQLIEDLIILPGGETSKNDSNGWELVVSAINQYGIDRHSYLMVIGGGAILDMVGYAAAVAHRGIRLIRIPTTVLSQNDSG
VGVKNSINYFGKKNFLGTFAPPVAVFNDSSFLVSLEDRDWRSGMAEAVKVSLIKNKVFFEWMESHVSELTHRDLTTMEHL
VYECARLHMEHIQNGDPFEFGSSRPLDFGHWFAHKLEYLANFSIRHGEAVAIGMALDSIYSYLSGFLQESELNRILNLLR
DLGFQFNHPVLLKNGKENLELALKEFQEHLGGKLTLLMLEGIGFPKEVYTIHLSLLESAYDRLVGWK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=285, Percent_Identity=33.6842105263158, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=364, Percent_Identity=27.4725274725275, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 44146; Mature: 44146

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKENRSKNIRSEFQVTYEYDVFFTKELFSLENILLSEFFQSKKTDKMKKKVLVVIDQGLF
CCCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHH
NFHNKILESIPQYFQSNVESVQLIEDLIILPGGETSKNDSNGWELVVSAINQYGIDRHSY
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
LMVIGGGAILDMVGYAAAVAHRGIRLIRIPTTVLSQNDSGVGVKNSINYFGKKNFLGTFA
EEEECCHHHHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCCCCCCHHHCCCCCCCCCCC
PPVAVFNDSSFLVSLEDRDWRSGMAEAVKVSLIKNKVFFEWMESHVSELTHRDLTTMEHL
CCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYECARLHMEHIQNGDPFEFGSSRPLDFGHWFAHKLEYLANFSIRHGEAVAIGMALDSIY
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
SYLSGFLQESELNRILNLLRDLGFQFNHPVLLKNGKENLELALKEFQEHLGGKLTLLMLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEEEEE
GIGFPKEVYTIHLSLLESAYDRLVGWK
CCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKENRSKNIRSEFQVTYEYDVFFTKELFSLENILLSEFFQSKKTDKMKKKVLVVIDQGLF
CCCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHH
NFHNKILESIPQYFQSNVESVQLIEDLIILPGGETSKNDSNGWELVVSAINQYGIDRHSY
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
LMVIGGGAILDMVGYAAAVAHRGIRLIRIPTTVLSQNDSGVGVKNSINYFGKKNFLGTFA
EEEECCHHHHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCCCCCCHHHCCCCCCCCCCC
PPVAVFNDSSFLVSLEDRDWRSGMAEAVKVSLIKNKVFFEWMESHVSELTHRDLTTMEHL
CCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYECARLHMEHIQNGDPFEFGSSRPLDFGHWFAHKLEYLANFSIRHGEAVAIGMALDSIY
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
SYLSGFLQESELNRILNLLRDLGFQFNHPVLLKNGKENLELALKEFQEHLGGKLTLLMLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEEEEE
GIGFPKEVYTIHLSLLESAYDRLVGWK
CCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA