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The map label for this gene is infC

Identifier: 183221770

GI number: 183221770

Start: 2468854

End: 2469417

Strand: Reverse

Name: infC

Synonym: LEPBI_I2400

Alternate gene names: 183221770

Gene position: 2469417-2468854 (Counterclockwise)

Preceding gene: 183221771

Following gene: 183221769

Centisome position: 68.6

GC content: 43.26

Gene sequence:

>564_bases
ATGCAGAAACGGCCCAACCCTAGAGGGAACCCAAACCAAGATAAATTCGCCCACATCAGAATTAACGAACAAATTACCAA
TGTAGCATCGATCCGGCTCGTCTCTGACGAAGGGTCCGATATCGTTACTCTGGACGAAGCTCTGAGAAGAGCTAAAGAAG
CTAACCTTGATTTGGTGGAAGTCTCGGGTGACCAAGATGTTCACGTCTGTAAGCTGATCGATTTTGGAAAATACAAATTC
GAACTTCTGAAAAAAACGAAAGAAGCGAAAAAGAAACAACACGTAGTCACGGTGAAAGAAATTAAAATCCGCCCGCGGAT
TGATAACCATGACTTCGAGATTAAGAAGCGTCATGCTTTAGAATTCTTGCAAAAGGGTGATAAGGTAAAAGTGACACTTC
GATTCCGAGGCAGAGAGATGGTTCACTCTGAAATTGGAATGAATATTGTTAACCGGTTTGTCGAGGACCTAAAAGAGCAT
GCCTCTCCCGAAAAAATGCCGGTACACGACGGAAAGACGATAGTGGTCGTGATGAACCCAATTGGTGAAAAACCTAAAGG
ATAA

Upstream 100 bases:

>100_bases
GTACGCTTTAGTAGGAGAAGTAGGGCAATTCATAAGAAATGTACTTGCATGCCTCGATTTTCATCCGAAATTGGAAATTG
AAAGAAATTTCGGAGACTGA

Downstream 100 bases:

>100_bases
AAACAACTATGTATAAGCTGAAGACAAATAGGGCAGCAGCCAAACGTTTTAAGTTTACCAAATCTGGTAAAATCAAACGT
GGTTGTGCGTTCCGAAGACA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MQKRPNPRGNPNQDKFAHIRINEQITNVASIRLVSDEGSDIVTLDEALRRAKEANLDLVEVSGDQDVHVCKLIDFGKYKF
ELLKKTKEAKKKQHVVTVKEIKIRPRIDNHDFEIKKRHALEFLQKGDKVKVTLRFRGREMVHSEIGMNIVNRFVEDLKEH
ASPEKMPVHDGKTIVVVMNPIGEKPKG

Sequences:

>Translated_187_residues
MQKRPNPRGNPNQDKFAHIRINEQITNVASIRLVSDEGSDIVTLDEALRRAKEANLDLVEVSGDQDVHVCKLIDFGKYKF
ELLKKTKEAKKKQHVVTVKEIKIRPRIDNHDFEIKKRHALEFLQKGDKVKVTLRFRGREMVHSEIGMNIVNRFVEDLKEH
ASPEKMPVHDGKTIVVVMNPIGEKPKG
>Mature_187_residues
MQKRPNPRGNPNQDKFAHIRINEQITNVASIRLVSDEGSDIVTLDEALRRAKEANLDLVEVSGDQDVHVCKLIDFGKYKF
ELLKKTKEAKKKQHVVTVKEIKIRPRIDNHDFEIKKRHALEFLQKGDKVKVTLRFRGREMVHSEIGMNIVNRFVEDLKEH
ASPEKMPVHDGKTIVVVMNPIGEKPKG

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=46.9512195121951, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_LEPBA (B0SCH4)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963399.1
- ProteinModelPortal:   B0SCH4
- SMR:   B0SCH4
- GeneID:   6388812
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2331
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   LBIF355278:LBF_2331-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 21517; Mature: 21517

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRPNPRGNPNQDKFAHIRINEQITNVASIRLVSDEGSDIVTLDEALRRAKEANLDLVE
CCCCCCCCCCCCCCCEEEEEECCHHCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCEEEE
VSGDQDVHVCKLIDFGKYKFELLKKTKEAKKKQHVVTVKEIKIRPRIDNHDFEIKKRHAL
ECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHH
EFLQKGDKVKVTLRFRGREMVHSEIGMNIVNRFVEDLKEHASPEKMPVHDGKTIVVVMNP
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
IGEKPKG
CCCCCCC
>Mature Secondary Structure
MQKRPNPRGNPNQDKFAHIRINEQITNVASIRLVSDEGSDIVTLDEALRRAKEANLDLVE
CCCCCCCCCCCCCCCEEEEEECCHHCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCEEEE
VSGDQDVHVCKLIDFGKYKFELLKKTKEAKKKQHVVTVKEIKIRPRIDNHDFEIKKRHAL
ECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHH
EFLQKGDKVKVTLRFRGREMVHSEIGMNIVNRFVEDLKEHASPEKMPVHDGKTIVVVMNP
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECC
IGEKPKG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA