Click here to switch to the map view.

The map label for this gene is tyrA [H]

Identifier: 183221756

GI number: 183221756

Start: 2458097

End: 2458990

Strand: Reverse

Name: tyrA [H]

Synonym: LEPBI_I2386

Alternate gene names: 183221756

Gene position: 2458990-2458097 (Counterclockwise)

Preceding gene: 183221757

Following gene: 183221755

Centisome position: 68.31

GC content: 39.26

Gene sequence:

>894_bases
ATGAATCTTCAGAAGGTCCTCATTTACGGAATGGGGCTTATGGGTGGATCACTTTCTCTTGCCATCCGAGACAAGTACCC
CAAAACAAAAATTCATGCAGTGGTTCGCTCAAAAAAAAGTAAAGAGTCCATCCTTGAAAAAAAATTAGCAGATCAAGTTT
TGACATTAGAGGAAAATCAAAAGATCAATTTTGAACTCTATGATCTTGTCGTTTTTAGTACACCTGTCGCGTCAGTATTA
AATCTGATTCCAAGTCTACCGAAGACAGGATCTACTATCTTTATGGATTTGGGTTCCACAAAACAATCGATTGTCGACTC
TGTGGACCAACACTTCGAAGATTTGGAACACAACTATATCTCCACGCATCCTATGTGTGGTTCAGAACAAACGGGTCCCC
TTGCGGCACTGAATGGGCTCTACCAAGATAAACTATGTATTTTGACAAAACCAAAACATGCCCGCCAAACTACTTTTGAT
GCCGTGAAAGTGTTTTGGGAAACGATTGGATCTTGGACGATCCAAATGGATGCAAAGGTCCATGATGAAACCTTGGCTTA
TGTTTCCCATTTACCTCATGTAATTTCGACTCTACTTGTCAATGTGGCTGGGAAAAACAAAACCACTATGGAACAAGTGT
CATCCATTCCAAAACCGATCACAGGTGGTGGGTTTCGTGATATGTCAAGGATCGCTGGCTCCAATGCCGAAATGTGGACT
TCTATTTTTGAAGAGAACAAATCATTTTTAAAAAACTCAATCGACGAATTTATCTCCGAACTTACAAACTTTCGAGAACT
ATTGATCGATGATATGACTCTCGATGAATCCAAAATTCATTCTATTTGGGAACTTGCACTCAAACAAAAAGAAACCATAC
AAAAATCAAAATGA

Upstream 100 bases:

>100_bases
AATCAGATCCAAAAATCAAATTCCTTCTTGAGTCCATCAAATCACAATGTAAGGCATTAAAAGTCCTCGGTTCTTATCCA
ACTGCAGGATCCTTTCCGAC

Downstream 100 bases:

>100_bases
AGTTTTTAAAAAATATTACAAAACTGAGCGGTTGTCAGGCGGCCATTTTAACCAACCAAAGTGCTTTTGGTTACAACGGA
AAGTATCACTTCCAAACTTA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNLQKVLIYGMGLMGGSLSLAIRDKYPKTKIHAVVRSKKSKESILEKKLADQVLTLEENQKINFELYDLVVFSTPVASVL
NLIPSLPKTGSTIFMDLGSTKQSIVDSVDQHFEDLEHNYISTHPMCGSEQTGPLAALNGLYQDKLCILTKPKHARQTTFD
AVKVFWETIGSWTIQMDAKVHDETLAYVSHLPHVISTLLVNVAGKNKTTMEQVSSIPKPITGGGFRDMSRIAGSNAEMWT
SIFEENKSFLKNSIDEFISELTNFRELLIDDMTLDESKIHSIWELALKQKETIQKSK

Sequences:

>Translated_297_residues
MNLQKVLIYGMGLMGGSLSLAIRDKYPKTKIHAVVRSKKSKESILEKKLADQVLTLEENQKINFELYDLVVFSTPVASVL
NLIPSLPKTGSTIFMDLGSTKQSIVDSVDQHFEDLEHNYISTHPMCGSEQTGPLAALNGLYQDKLCILTKPKHARQTTFD
AVKVFWETIGSWTIQMDAKVHDETLAYVSHLPHVISTLLVNVAGKNKTTMEQVSSIPKPITGGGFRDMSRIAGSNAEMWT
SIFEENKSFLKNSIDEFISELTNFRELLIDDMTLDESKIHSIWELALKQKETIQKSK
>Mature_297_residues
MNLQKVLIYGMGLMGGSLSLAIRDKYPKTKIHAVVRSKKSKESILEKKLADQVLTLEENQKINFELYDLVVFSTPVASVL
NLIPSLPKTGSTIFMDLGSTKQSIVDSVDQHFEDLEHNYISTHPMCGSEQTGPLAALNGLYQDKLCILTKPKHARQTTFD
AVKVFWETIGSWTIQMDAKVHDETLAYVSHLPHVISTLLVNVAGKNKTTMEQVSSIPKPITGGGFRDMSRIAGSNAEMWT
SIFEENKSFLKNSIDEFISELTNFRELLIDDMTLDESKIHSIWELALKQKETIQKSK

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 33335; Mature: 33335

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQKVLIYGMGLMGGSLSLAIRDKYPKTKIHAVVRSKKSKESILEKKLADQVLTLEENQ
CCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
KINFELYDLVVFSTPVASVLNLIPSLPKTGSTIFMDLGSTKQSIVDSVDQHFEDLEHNYI
CCCEEEEHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
STHPMCGSEQTGPLAALNGLYQDKLCILTKPKHARQTTFDAVKVFWETIGSWTIQMDAKV
CCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCHH
HDETLAYVSHLPHVISTLLVNVAGKNKTTMEQVSSIPKPITGGGFRDMSRIAGSNAEMWT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHH
SIFEENKSFLKNSIDEFISELTNFRELLIDDMTLDESKIHSIWELALKQKETIQKSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLQKVLIYGMGLMGGSLSLAIRDKYPKTKIHAVVRSKKSKESILEKKLADQVLTLEENQ
CCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
KINFELYDLVVFSTPVASVLNLIPSLPKTGSTIFMDLGSTKQSIVDSVDQHFEDLEHNYI
CCCEEEEHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
STHPMCGSEQTGPLAALNGLYQDKLCILTKPKHARQTTFDAVKVFWETIGSWTIQMDAKV
CCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCHH
HDETLAYVSHLPHVISTLLVNVAGKNKTTMEQVSSIPKPITGGGFRDMSRIAGSNAEMWT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHH
SIFEENKSFLKNSIDEFISELTNFRELLIDDMTLDESKIHSIWELALKQKETIQKSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]