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The map label for this gene is mrp [H]

Identifier: 183221720

GI number: 183221720

Start: 2419330

End: 2420382

Strand: Reverse

Name: mrp [H]

Synonym: LEPBI_I2349

Alternate gene names: 183221720

Gene position: 2420382-2419330 (Counterclockwise)

Preceding gene: 183221721

Following gene: 183221719

Centisome position: 67.24

GC content: 44.54

Gene sequence:

>1053_bases
ATGGCAAATGATAAAATTGATTTAACCTCCATCCAACGGCAACTCATGCAAGTGAAACACCCGGAACTCAAAAAAGACAT
TGTGAGTCTCGGAATGGTAGCACAAGTCACACCAACTGATGATGGAATTGAAATCCTCATCAAAACTCCCAATGCAGATC
GTCGTTTGCAAATTGGACTTGAAGCACAAACAAGACAACTCATCTCCAAAATCGAAGGTGCTGGGAAAGTTAAGATTAAA
TTTGAAGTCGACCAAAACCTCAAAATGGAAGATGGGAACCGAATCTTTGGTGTGAAAAAAGTCATCGCTGTTGGTTCGGG
AAAAGGTGGGGTCGGTAAGTCCACTGTCACTGCGAACTTAGCGAGTACCCTTGCAATGAGTGGCAAAAAAGTGGGAATCT
TAGATGCCGATATCTATGGACCTTCCCTCGGAAAGATGTTTGGGATCAATGGCCGAGTGGCATTAAAATCCGAAGAAGAT
AAAATTTATCCAATCGAAAAACATGGAATCAAACTCATTTCCTTTTCCTTCCTTGTGACAGAAGACCAACCTGTTGTTTG
GCGTGGACCAATGCTTGGGAAAGCCATCGAACAGTTCTTATACGATGTGGTTTGGGGGGAACTAGATTACCTTTTCATTG
ACCTACCACCAGGAACAGGAGACGTCCAACTCTCTCTTGCCCAACTCATTGACCTTGATGGTGCTGTGATTGTCACCACT
CCACAAGAAGTGGCAGTACTCGATGCAGGTCGTGCTGCTGCGATGTTCAAACAAGTGAAAGTTCCCATCCTCGGGATTGT
GGAAAACATGAGTGGCTTTGCTTGTCCGAAATGTGGGCATGTCACCGATGTTTTTTCCAAAGGGGGAGGGGAAAAACTTT
CCAAACAAGTCGGAGTCCCGGAACTGGGAGCAGTCCCTCTCACACTTGATGTCATGAGTTCGGGAGAATCGGGGAAACCA
GCCTTACTTGACGCAAAAGACTCTCCTTTGAAAGAGGCATATTTTTTGATCGCAAAGAATTTAGAAGAACAAATTGCGAA
TTGGGAAGAGTAA

Upstream 100 bases:

>100_bases
CAAACCCATTACCGTCGTTTTATATATTCAGAAAACAAATTCACAGAGACAAATCCCATTCTTTACGAAGAGACTGAGGG
AGTTGTCTAAAGGACATACC

Downstream 100 bases:

>100_bases
AAATCACTTGTTTCTTCTCTGGCTTTTCTTAGTCTAAAGGATACACTATGAATTTTGAACGCGGTTCCAAACCAAATCCA
ACAGGGAATTTAATCGCATA

Product: Mrp family ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MANDKIDLTSIQRQLMQVKHPELKKDIVSLGMVAQVTPTDDGIEILIKTPNADRRLQIGLEAQTRQLISKIEGAGKVKIK
FEVDQNLKMEDGNRIFGVKKVIAVGSGKGGVGKSTVTANLASTLAMSGKKVGILDADIYGPSLGKMFGINGRVALKSEED
KIYPIEKHGIKLISFSFLVTEDQPVVWRGPMLGKAIEQFLYDVVWGELDYLFIDLPPGTGDVQLSLAQLIDLDGAVIVTT
PQEVAVLDAGRAAAMFKQVKVPILGIVENMSGFACPKCGHVTDVFSKGGGEKLSKQVGVPELGAVPLTLDVMSSGESGKP
ALLDAKDSPLKEAYFLIAKNLEEQIANWEE

Sequences:

>Translated_350_residues
MANDKIDLTSIQRQLMQVKHPELKKDIVSLGMVAQVTPTDDGIEILIKTPNADRRLQIGLEAQTRQLISKIEGAGKVKIK
FEVDQNLKMEDGNRIFGVKKVIAVGSGKGGVGKSTVTANLASTLAMSGKKVGILDADIYGPSLGKMFGINGRVALKSEED
KIYPIEKHGIKLISFSFLVTEDQPVVWRGPMLGKAIEQFLYDVVWGELDYLFIDLPPGTGDVQLSLAQLIDLDGAVIVTT
PQEVAVLDAGRAAAMFKQVKVPILGIVENMSGFACPKCGHVTDVFSKGGGEKLSKQVGVPELGAVPLTLDVMSSGESGKP
ALLDAKDSPLKEAYFLIAKNLEEQIANWEE
>Mature_349_residues
ANDKIDLTSIQRQLMQVKHPELKKDIVSLGMVAQVTPTDDGIEILIKTPNADRRLQIGLEAQTRQLISKIEGAGKVKIKF
EVDQNLKMEDGNRIFGVKKVIAVGSGKGGVGKSTVTANLASTLAMSGKKVGILDADIYGPSLGKMFGINGRVALKSEEDK
IYPIEKHGIKLISFSFLVTEDQPVVWRGPMLGKAIEQFLYDVVWGELDYLFIDLPPGTGDVQLSLAQLIDLDGAVIVTTP
QEVAVLDAGRAAAMFKQVKVPILGIVENMSGFACPKCGHVTDVFSKGGGEKLSKQVGVPELGAVPLTLDVMSSGESGKPA
LLDAKDSPLKEAYFLIAKNLEEQIANWEE

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=285, Percent_Identity=45.2631578947368, Blast_Score=241, Evalue=7e-64,
Organism=Homo sapiens, GI6912540, Length=258, Percent_Identity=44.1860465116279, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI118572611, Length=254, Percent_Identity=42.9133858267717, Blast_Score=192, Evalue=4e-49,
Organism=Escherichia coli, GI87082045, Length=333, Percent_Identity=40.2402402402402, Blast_Score=250, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI25143050, Length=262, Percent_Identity=40.4580152671756, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322188, Length=260, Percent_Identity=43.0769230769231, Blast_Score=200, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321347, Length=262, Percent_Identity=38.1679389312977, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24667611, Length=256, Percent_Identity=41.40625, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI221511043, Length=262, Percent_Identity=37.7862595419847, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI19921440, Length=257, Percent_Identity=38.5214007782101, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37684; Mature: 37553

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANDKIDLTSIQRQLMQVKHPELKKDIVSLGMVAQVTPTDDGIEILIKTPNADRRLQIGL
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCEEEECC
EAQTRQLISKIEGAGKVKIKFEVDQNLKMEDGNRIFGVKKVIAVGSGKGGVGKSTVTANL
CHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCEEEEEEEEEEECCCCCCCCCCHHHHHH
ASTLAMSGKKVGILDADIYGPSLGKMFGINGRVALKSEEDKIYPIEKHGIKLISFSFLVT
HHHHHHCCCEEEEEECCCCCCCCHHEECCCCEEEEECCCCCEEEEHHCCEEEEEEEEEEE
EDQPVVWRGPMLGKAIEQFLYDVVWGELDYLFIDLPPGTGDVQLSLAQLIDLDGAVIVTT
CCCCEEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEHHHHHCCCCEEEEEC
PQEVAVLDAGRAAAMFKQVKVPILGIVENMSGFACPKCGHVTDVFSKGGGEKLSKQVGVP
CCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCC
ELGAVPLTLDVMSSGESGKPALLDAKDSPLKEAYFLIAKNLEEQIANWEE
CCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ANDKIDLTSIQRQLMQVKHPELKKDIVSLGMVAQVTPTDDGIEILIKTPNADRRLQIGL
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCEEEECC
EAQTRQLISKIEGAGKVKIKFEVDQNLKMEDGNRIFGVKKVIAVGSGKGGVGKSTVTANL
CHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCEEEEEEEEEEECCCCCCCCCCHHHHHH
ASTLAMSGKKVGILDADIYGPSLGKMFGINGRVALKSEEDKIYPIEKHGIKLISFSFLVT
HHHHHHCCCEEEEEECCCCCCCCHHEECCCCEEEEECCCCCEEEEHHCCEEEEEEEEEEE
EDQPVVWRGPMLGKAIEQFLYDVVWGELDYLFIDLPPGTGDVQLSLAQLIDLDGAVIVTT
CCCCEEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEHHHHHCCCCEEEEEC
PQEVAVLDAGRAAAMFKQVKVPILGIVENMSGFACPKCGHVTDVFSKGGGEKLSKQVGVP
CCCEEEEECCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCC
ELGAVPLTLDVMSSGESGKPALLDAKDSPLKEAYFLIAKNLEEQIANWEE
CCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]