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The map label for this gene is rsbV [H]

Identifier: 183221701

GI number: 183221701

Start: 2400050

End: 2400385

Strand: Reverse

Name: rsbV [H]

Synonym: LEPBI_I2328

Alternate gene names: 183221701

Gene position: 2400385-2400050 (Counterclockwise)

Preceding gene: 183221702

Following gene: 183221700

Centisome position: 66.68

GC content: 37.8

Gene sequence:

>336_bases
ATGGAAATCACCAGAAGGGAAAAAGATAAAATCGTAGTACTCGATATTAACGGGGAAATCGACCTTTATAACGCGCCTGA
GATCAAGGATGTAATCGCCAAATTGATCGAAGAACAAAAGTATTGCATCGTCATCAATCTCGAGAAGGTATCTTACATCG
ACTCTTCCGGAATTGGAGCTTTAATTTCAAGTTTGTCCAACCTGAAAAAATACCAAGGTGGTTTAAAAATCATCAACGTA
GCAGGTTCTGTTCGTAAGGTATTTGAACTCACTAAGTTGACTTCATTTTTTGAAATTTTCGATAGCGAAGACGAAGCAGT
CACTGCTTTCAAATAG

Upstream 100 bases:

>100_bases
TAGCTAAAATTATTAGGTTGACGTACCCATTTTTTTTGAATGCAATTGTACCGTCATTTCTACATTGATTGTAGCTTCAT
TGAGGAGTCTCTAGACACAC

Downstream 100 bases:

>100_bases
AAGAGGAAGCGTATTTTGCGCTTCTCTCTTTTTTATACCCCCCTACCAAACATTAAGGAGTTTGTTATGTTAAAAAAGAA
AAAGACATCAGTCTTTCTCT

Product: putative anti-sigma factor antagonist

Products: NA

Alternate protein names: Anti-anti-sigma-B factor [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MEITRREKDKIVVLDINGEIDLYNAPEIKDVIAKLIEEQKYCIVINLEKVSYIDSSGIGALISSLSNLKKYQGGLKIINV
AGSVRKVFELTKLTSFFEIFDSEDEAVTAFK

Sequences:

>Translated_111_residues
MEITRREKDKIVVLDINGEIDLYNAPEIKDVIAKLIEEQKYCIVINLEKVSYIDSSGIGALISSLSNLKKYQGGLKIINV
AGSVRKVFELTKLTSFFEIFDSEDEAVTAFK
>Mature_111_residues
MEITRREKDKIVVLDINGEIDLYNAPEIKDVIAKLIEEQKYCIVINLEKVSYIDSSGIGALISSLSNLKKYQGGLKIINV
AGSVRKVFELTKLTSFFEIFDSEDEAVTAFK

Specific function: Positive regulator of sigma-B activity. Non- phosphorylated rsbV binds to rsbW, preventing its association with sigma-B. When phosphorylated, releases rsbW, which is then free to complex with and inactivate sigma-B [H]

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003658
- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12476; Mature: 12476

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITRREKDKIVVLDINGEIDLYNAPEIKDVIAKLIEEQKYCIVINLEKVSYIDSSGIGA
CCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHCCCCEEEEEEEHHHEEECCCCHHH
LISSLSNLKKYQGGLKIINVAGSVRKVFELTKLTSFFEIFDSEDEAVTAFK
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure
MEITRREKDKIVVLDINGEIDLYNAPEIKDVIAKLIEEQKYCIVINLEKVSYIDSSGIGA
CCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHHHCCCCEEEEEEEHHHEEECCCCHHH
LISSLSNLKKYQGGLKIINVAGSVRKVFELTKLTSFFEIFDSEDEAVTAFK
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]