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The map label for this gene is speD [H]

Identifier: 183221660

GI number: 183221660

Start: 2351411

End: 2352172

Strand: Direct

Name: speD [H]

Synonym: LEPBI_I2285

Alternate gene names: 183221660

Gene position: 2351411-2352172 (Clockwise)

Preceding gene: 183221657

Following gene: 183221663

Centisome position: 65.32

GC content: 38.19

Gene sequence:

>762_bases
ATGGATAAAGAAAAAATCAAACTTTCCGGTTTCAATAATCTGACAAAAGTTTTGAGTTTTAACCTCTACGATTTTTGCAT
CACTCTCGATGACGAACAAAAAGGTAGGTATGTTAGTTATATCCACGACAAGTACAATGCGAGTAAAATTACAGAGATTT
CAAAAGAGATCGTAAAAAGAATTGATGCCAATATACTATCAGTTTCCGCTCAGGATTACGATCCGGTAGGTGCTTCTGCT
ATGGTTCTTATGAGCGATGTGAAAGGTGGTGGAAATCCCATCCCATCGACGCAGGTCAGCATGCACCTAGACAAATCACA
CATCACTGTACACACCTATCCCGATGCGGCCGATCCTGACGGGATTTGTTCTTTCCGCGTGGACATTGACATTTCAACCT
GTGGAGAAATCATTCCACTTGATTCCATAAATTATTTGTTTGAAGCCTTCGAATGTGATGTGGTCTATATTGATTATGTA
GTGCGAGGTTACACTCGACTTGCCGATGGAAGGAAAATTTATAACGACCATCACTTCAATTCTATCCTCGATTTCATCAA
ACCAGAAATCAAAAGGAATTATACATTTTTGTCCGACATCAACATGCCACAAGATAATACTTGGCAGACAAAGATGATGA
TAAAAGAACTAGGTCCTGAAAACTATTTACTCAATCCAGAAGATATCTCGCATCCAGATGTTCAGAACAAAATGAAATTA
CTTAGAGAAGAGATGAAAGAAGTATATCATATGATCCACTAA

Upstream 100 bases:

>100_bases
ATTCCATCTTGTTTTCCATGACTTTTCTATCACCCCTTTGTTATTTCAGTTGCTTCTTACCTAATCACCGAATTTCTGTT
CTTTATACAAGCAGGTAGCA

Downstream 100 bases:

>100_bases
AGGATCATTTTTGCATTGGAGCTGATTGCTTTTTGGATTTGTTTCCAATCTTTGTCTTCGAGTTTCGGGAGTGCAAATAT
TTCTGTGCGATGTGGTGGGA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDKEKIKLSGFNNLTKVLSFNLYDFCITLDDEQKGRYVSYIHDKYNASKITEISKEIVKRIDANILSVSAQDYDPVGASA
MVLMSDVKGGGNPIPSTQVSMHLDKSHITVHTYPDAADPDGICSFRVDIDISTCGEIIPLDSINYLFEAFECDVVYIDYV
VRGYTRLADGRKIYNDHHFNSILDFIKPEIKRNYTFLSDINMPQDNTWQTKMMIKELGPENYLLNPEDISHPDVQNKMKL
LREEMKEVYHMIH

Sequences:

>Translated_253_residues
MDKEKIKLSGFNNLTKVLSFNLYDFCITLDDEQKGRYVSYIHDKYNASKITEISKEIVKRIDANILSVSAQDYDPVGASA
MVLMSDVKGGGNPIPSTQVSMHLDKSHITVHTYPDAADPDGICSFRVDIDISTCGEIIPLDSINYLFEAFECDVVYIDYV
VRGYTRLADGRKIYNDHHFNSILDFIKPEIKRNYTFLSDINMPQDNTWQTKMMIKELGPENYLLNPEDISHPDVQNKMKL
LREEMKEVYHMIH
>Mature_253_residues
MDKEKIKLSGFNNLTKVLSFNLYDFCITLDDEQKGRYVSYIHDKYNASKITEISKEIVKRIDANILSVSAQDYDPVGASA
MVLMSDVKGGGNPIPSTQVSMHLDKSHITVHTYPDAADPDGICSFRVDIDISTCGEIIPLDSINYLFEAFECDVVYIDYV
VRGYTRLADGRKIYNDHHFNSILDFIKPEIKRNYTFLSDINMPQDNTWQTKMMIKELGPENYLLNPEDISHPDVQNKMKL
LREEMKEVYHMIH

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786311, Length=258, Percent_Identity=44.1860465116279, Blast_Score=217, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 29089; Mature: 29089

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEKIKLSGFNNLTKVLSFNLYDFCITLDDEQKGRYVSYIHDKYNASKITEISKEIVKR
CCCCEEEECCCHHHHHHHHCCEEEEEEEECCCCCCCEEEEHHHCCCHHHHHHHHHHHHHH
IDANILSVSAQDYDPVGASAMVLMSDVKGGGNPIPSTQVSMHLDKSHITVHTYPDAADPD
HCCCEEEEECCCCCCCCCHHHEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCC
GICSFRVDIDISTCGEIIPLDSINYLFEAFECDVVYIDYVVRGYTRLADGRKIYNDHHFN
CEEEEEEEEEHHCCCCEECCCHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHCCHHHH
SILDFIKPEIKRNYTFLSDINMPQDNTWQTKMMIKELGPENYLLNPEDISHPDVQNKMKL
HHHHHHCHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHH
LREEMKEVYHMIH
HHHHHHHHHHHCC
>Mature Secondary Structure
MDKEKIKLSGFNNLTKVLSFNLYDFCITLDDEQKGRYVSYIHDKYNASKITEISKEIVKR
CCCCEEEECCCHHHHHHHHCCEEEEEEEECCCCCCCEEEEHHHCCCHHHHHHHHHHHHHH
IDANILSVSAQDYDPVGASAMVLMSDVKGGGNPIPSTQVSMHLDKSHITVHTYPDAADPD
HCCCEEEEECCCCCCCCCHHHEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCC
GICSFRVDIDISTCGEIIPLDSINYLFEAFECDVVYIDYVVRGYTRLADGRKIYNDHHFN
CEEEEEEEEEHHCCCCEECCCHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHCCHHHH
SILDFIKPEIKRNYTFLSDINMPQDNTWQTKMMIKELGPENYLLNPEDISHPDVQNKMKL
HHHHHHCHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHH
LREEMKEVYHMIH
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA