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The map label for this gene is gstA [H]

Identifier: 183221643

GI number: 183221643

Start: 2336452

End: 2337045

Strand: Reverse

Name: gstA [H]

Synonym: LEPBI_I2267

Alternate gene names: 183221643

Gene position: 2337045-2336452 (Counterclockwise)

Preceding gene: 183221647

Following gene: 183221609

Centisome position: 64.92

GC content: 34.85

Gene sequence:

>594_bases
ATGATCGAATTTTATGAATTTAAAACATCTGGAAATTGCTATAAAATCAAGTTGATGTTGTCGCTTTTGGATCTAAAATT
TGAAAGCCGATTTATAAATCCAATTGATAAAGAGCATAAGTCTGAACAATTTTTAGAGTTGAATCCATTTGGACAAGTGC
CTGTTCTGAAAGATGGTTCAATTATCCTTCGCGATAGCCAAGCAATATTAGTTTATTTAGCAAGAAAATACGGTAAAGAA
CATTGGTTCCCAATTGAACCGAGTGATATGGCTGAAATTGTATCTTGGTTATCGATTGCTACTAATGAAGTTGCTCGAGG
ACCTGCCTTATTACGAATGCATTACTTACTTGGCCGAAAAATCGATTTAGAGGAAGCGGTATCAACTACTGATCAAATTC
TATCAATATTGGATAACATGCTTTCCAGTAGAGATTGGTTGGTGAATCAGGAGGTTAGTATAGCTGATATTGCTATATAT
CCATATCTGGCTTTGAGCCACCAAGGAAATATTGATCTAAGTAAATATACGAATATAGTGAATTGGATGAGTCGGGTTGA
ACACCTTCCTGGGTATGTACAATTTACACAATAA

Upstream 100 bases:

>100_bases
CATATGTGTTTTGATTGCAAAAAACGGAAATCGTTTTTGTTTCTTTTTGAAACAAAAAAAACATTGCCAATGCACTAGAG
AACTAAGTATAAATTTGATA

Downstream 100 bases:

>100_bases
AAGCTTGCGTGTTAACAATACATTCCAATGAATTTGAAACATGATGAATTCACGAAAAACTTATTTTTATTGAATCAAAA
TTTTGTTTAATGGCGGGAAT

Product: putative glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIEFYEFKTSGNCYKIKLMLSLLDLKFESRFINPIDKEHKSEQFLELNPFGQVPVLKDGSIILRDSQAILVYLARKYGKE
HWFPIEPSDMAEIVSWLSIATNEVARGPALLRMHYLLGRKIDLEEAVSTTDQILSILDNMLSSRDWLVNQEVSIADIAIY
PYLALSHQGNIDLSKYTNIVNWMSRVEHLPGYVQFTQ

Sequences:

>Translated_197_residues
MIEFYEFKTSGNCYKIKLMLSLLDLKFESRFINPIDKEHKSEQFLELNPFGQVPVLKDGSIILRDSQAILVYLARKYGKE
HWFPIEPSDMAEIVSWLSIATNEVARGPALLRMHYLLGRKIDLEEAVSTTDQILSILDNMLSSRDWLVNQEVSIADIAIY
PYLALSHQGNIDLSKYTNIVNWMSRVEHLPGYVQFTQ
>Mature_197_residues
MIEFYEFKTSGNCYKIKLMLSLLDLKFESRFINPIDKEHKSEQFLELNPFGQVPVLKDGSIILRDSQAILVYLARKYGKE
HWFPIEPSDMAEIVSWLSIATNEVARGPALLRMHYLLGRKIDLEEAVSTTDQILSILDNMLSSRDWLVNQEVSIADIAIY
PYLALSHQGNIDLSKYTNIVNWMSRVEHLPGYVQFTQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI167466164, Length=201, Percent_Identity=27.8606965174129, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4504187, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI124249394, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1788640, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI87081789, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17864592, Length=195, Percent_Identity=26.1538461538462, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17933730, Length=198, Percent_Identity=26.2626262626263, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI85725204, Length=194, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737923, Length=194, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=27.1794871794872, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45549270, Length=193, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17864596, Length=193, Percent_Identity=23.8341968911917, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571670, Length=174, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130123, Length=204, Percent_Identity=25.4901960784314, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654992, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654979, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922526, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130115, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654975, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=22.7979274611399, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922932, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922532, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24654983, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646249, Length=186, Percent_Identity=24.7311827956989, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922160, Length=182, Percent_Identity=25.8241758241758, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646251, Length=196, Percent_Identity=22.9591836734694, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22758; Mature: 22758

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFYEFKTSGNCYKIKLMLSLLDLKFESRFINPIDKEHKSEQFLELNPFGQVPVLKDGS
CCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCCEEECCC
IILRDSQAILVYLARKYGKEHWFPIEPSDMAEIVSWLSIATNEVARGPALLRMHYLLGRK
EEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
IDLEEAVSTTDQILSILDNMLSSRDWLVNQEVSIADIAIYPYLALSHQGNIDLSKYTNIV
CCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHEEEEHHEEEECCCCCCCHHHHHHHH
NWMSRVEHLPGYVQFTQ
HHHHHHHHCCCEEEECC
>Mature Secondary Structure
MIEFYEFKTSGNCYKIKLMLSLLDLKFESRFINPIDKEHKSEQFLELNPFGQVPVLKDGS
CCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCCCCEEECCC
IILRDSQAILVYLARKYGKEHWFPIEPSDMAEIVSWLSIATNEVARGPALLRMHYLLGRK
EEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
IDLEEAVSTTDQILSILDNMLSSRDWLVNQEVSIADIAIYPYLALSHQGNIDLSKYTNIV
CCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHEEEEHHEEEECCCCCCCHHHHHHHH
NWMSRVEHLPGYVQFTQ
HHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA