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The map label for this gene is sucC [H]

Identifier: 183221438

GI number: 183221438

Start: 2144575

End: 2145786

Strand: Direct

Name: sucC [H]

Synonym: LEPBI_I2056

Alternate gene names: 183221438

Gene position: 2144575-2145786 (Clockwise)

Preceding gene: 183221437

Following gene: 183221439

Centisome position: 59.58

GC content: 45.05

Gene sequence:

>1212_bases
TTGGCGAAGGCCTACGGACGTACCAATGACATAAGGAAATCCATGAAAGTCCACGAATACCAGGCCAAAGAAATCCTACG
TAGACACAATGCCAACGTTCCGTTCGGAAAGGTCATCGACGCTGTCGGTGATTTCGAAAAGGCATATAACGAAGTTGTCC
AAAAATCACCAGTTGTTGTGGTGAAAGCCCAAATCCACGCAGGTGGACGCGGAAAAGGTGGCGGTGTGAAAGTCGCCAAA
ACAAAAGACGATGCAAAAGCGGCCGCAGAAAAAATTCTCGGGATGCAACTCATCACTCCGCAAACAGGACCAGAAGGGAA
AAAAGTCCTCAAAGTCTATTTAGAACAAGGACTTGAAATTGCAAAGGAATACTACCTTTCTATCCTTCTTGACCGTGCCA
TTCGTAAAACCATCATCATGGCTTCCACAGAAGGTGGGATGGAAATTGAAGAAGTGGCAGAAACCCACCCTGAAAAAATC
ATCAAAATCCAAATTGATCCAGGAATTGGTATCCAAGGATCTCAAGTGAGAGAACTTGCGTTTGCTCTCGGGATTCCAAC
AGAAGCACAAAAATCCTTCACGGCTCTTGTGAACTCAGTTTACAACGCCTACATCAAAGAAGATGCAGCCCTACTTGAGA
TCAACCCCCTCATCCTCACCAAACAAAACGAAATCATCGCAGGGGACTGCAAGATGGACTTGGATGAAAACGCACTTTAC
CGTCATCCAGACAACGAAGCACTTCGAGATATTACAGAAGAAGATCCATACGAAGTCAAAGCCAAAGAATACAACCTCAA
CTATGTTAAGTTAGATGGAAACATCGGTTGTATGGTCAACGGTGCAGGTCTTGCCATGGCAACCATGGACATCGTTAAGT
TAGCTGGTGCTGAACCTGCAAACTTTTTGGATGTTGGAGGTGGAGCAAACCCAACAACCGTGGAAAATGGTTTCAGACTC
ATTCTTTCTGATCCAAACGTAAAAGGAATTTTTGTGAACGTATTTGGTGGAATCGTACGATGTGACCGCGTTGCGGTTGG
TATCATCGAAGCGACCAAAAAAGTGAACGTATCCGTTCCAGTTGTGGTTCGTTTGAAAGGAACGAACGCAGAAGAAGGGA
AAAAAATCCTGAACGAATCTGGGATGAACATTGTGGGAGTCGAAGGGCTCCGTGACGCGGCAGACAAAATTGTCTCCCTA
ATCAAAAAATAG

Upstream 100 bases:

>100_bases
AATGTTCGTCTACCGATTCTCTTTCGTCCCTCTTTCCTTACTTCCTTTCAATCCGTCTTGACAATCTCACCCAACCCTTG
AGGCTTACCCTAGTGATCCG

Downstream 100 bases:

>100_bases
GAAACAGGAAACATGGCTGTATTAGTAGATGAAAATACAAGAGTAGTTGTACAGGGGATCACTGGAAAAGAAGGTTCCTT
CCACGCAACACAAATGTTGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAKAYGRTNDIRKSMKVHEYQAKEILRRHNANVPFGKVIDAVGDFEKAYNEVVQKSPVVVVKAQIHAGGRGKGGGVKVAK
TKDDAKAAAEKILGMQLITPQTGPEGKKVLKVYLEQGLEIAKEYYLSILLDRAIRKTIIMASTEGGMEIEEVAETHPEKI
IKIQIDPGIGIQGSQVRELAFALGIPTEAQKSFTALVNSVYNAYIKEDAALLEINPLILTKQNEIIAGDCKMDLDENALY
RHPDNEALRDITEEDPYEVKAKEYNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANPTTVENGFRL
ILSDPNVKGIFVNVFGGIVRCDRVAVGIIEATKKVNVSVPVVVRLKGTNAEEGKKILNESGMNIVGVEGLRDAADKIVSL
IKK

Sequences:

>Translated_403_residues
MAKAYGRTNDIRKSMKVHEYQAKEILRRHNANVPFGKVIDAVGDFEKAYNEVVQKSPVVVVKAQIHAGGRGKGGGVKVAK
TKDDAKAAAEKILGMQLITPQTGPEGKKVLKVYLEQGLEIAKEYYLSILLDRAIRKTIIMASTEGGMEIEEVAETHPEKI
IKIQIDPGIGIQGSQVRELAFALGIPTEAQKSFTALVNSVYNAYIKEDAALLEINPLILTKQNEIIAGDCKMDLDENALY
RHPDNEALRDITEEDPYEVKAKEYNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANPTTVENGFRL
ILSDPNVKGIFVNVFGGIVRCDRVAVGIIEATKKVNVSVPVVVRLKGTNAEEGKKILNESGMNIVGVEGLRDAADKIVSL
IKK
>Mature_402_residues
AKAYGRTNDIRKSMKVHEYQAKEILRRHNANVPFGKVIDAVGDFEKAYNEVVQKSPVVVVKAQIHAGGRGKGGGVKVAKT
KDDAKAAAEKILGMQLITPQTGPEGKKVLKVYLEQGLEIAKEYYLSILLDRAIRKTIIMASTEGGMEIEEVAETHPEKII
KIQIDPGIGIQGSQVRELAFALGIPTEAQKSFTALVNSVYNAYIKEDAALLEINPLILTKQNEIIAGDCKMDLDENALYR
HPDNEALRDITEEDPYEVKAKEYNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANPTTVENGFRLI
LSDPNVKGIFVNVFGGIVRCDRVAVGIIEATKKVNVSVPVVVRLKGTNAEEGKKILNESGMNIVGVEGLRDAADKIVSLI
KK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=397, Percent_Identity=41.3098236775819, Blast_Score=301, Evalue=8e-82,
Organism=Homo sapiens, GI157779135, Length=388, Percent_Identity=41.4948453608247, Blast_Score=295, Evalue=6e-80,
Organism=Homo sapiens, GI294862256, Length=390, Percent_Identity=40, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=50.7731958762887, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17567829, Length=398, Percent_Identity=42.4623115577889, Blast_Score=310, Evalue=7e-85,
Organism=Caenorhabditis elegans, GI17539378, Length=401, Percent_Identity=42.14463840399, Blast_Score=310, Evalue=9e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=402, Percent_Identity=44.7761194029851, Blast_Score=340, Evalue=3e-94,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=44.9748743718593, Blast_Score=311, Evalue=5e-85,
Organism=Drosophila melanogaster, GI161078106, Length=397, Percent_Identity=42.0654911838791, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24645208, Length=397, Percent_Identity=42.0654911838791, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361397, Length=398, Percent_Identity=41.9597989949749, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI281361395, Length=398, Percent_Identity=41.9597989949749, Blast_Score=302, Evalue=3e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43667; Mature: 43536

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAYGRTNDIRKSMKVHEYQAKEILRRHNANVPFGKVIDAVGDFEKAYNEVVQKSPVVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
VKAQIHAGGRGKGGGVKVAKTKDDAKAAAEKILGMQLITPQTGPEGKKVLKVYLEQGLEI
EEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH
AKEYYLSILLDRAIRKTIIMASTEGGMEIEEVAETHPEKIIKIQIDPGIGIQGSQVRELA
HHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH
FALGIPTEAQKSFTALVNSVYNAYIKEDAALLEINPLILTKQNEIIAGDCKMDLDENALY
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEECCCCCCCCCCCCE
RHPDNEALRDITEEDPYEVKAKEYNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPA
ECCCCHHHHHCCCCCCCEEEEEEECCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCC
NFLDVGGGANPTTVENGFRLILSDPNVKGIFVNVFGGIVRCDRVAVGIIEATKKVNVSVP
CEEECCCCCCCCEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHEEHHHHCCEECCEEE
VVVRLKGTNAEEGKKILNESGMNIVGVEGLRDAADKIVSLIKK
EEEEEECCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKAYGRTNDIRKSMKVHEYQAKEILRRHNANVPFGKVIDAVGDFEKAYNEVVQKSPVVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
VKAQIHAGGRGKGGGVKVAKTKDDAKAAAEKILGMQLITPQTGPEGKKVLKVYLEQGLEI
EEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHHH
AKEYYLSILLDRAIRKTIIMASTEGGMEIEEVAETHPEKIIKIQIDPGIGIQGSQVRELA
HHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH
FALGIPTEAQKSFTALVNSVYNAYIKEDAALLEINPLILTKQNEIIAGDCKMDLDENALY
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEECCCCCCCCCCCCE
RHPDNEALRDITEEDPYEVKAKEYNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPA
ECCCCHHHHHCCCCCCCEEEEEEECCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCC
NFLDVGGGANPTTVENGFRLILSDPNVKGIFVNVFGGIVRCDRVAVGIIEATKKVNVSVP
CEEECCCCCCCCEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHEEHHHHCCEECCEEE
VVVRLKGTNAEEGKKILNESGMNIVGVEGLRDAADKIVSLIKK
EEEEEECCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA