| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is fabG [H]
Identifier: 183221362
GI number: 183221362
Start: 2058501
End: 2059268
Strand: Direct
Name: fabG [H]
Synonym: LEPBI_I1980
Alternate gene names: 183221362
Gene position: 2058501-2059268 (Clockwise)
Preceding gene: 183221361
Following gene: 183221363
Centisome position: 57.19
GC content: 46.09
Gene sequence:
>768_bases ATGGAATTAAAAGGTGCAAACATTCTCGTCACCGGATCTGCCGGTGGACTCGGAAAGGCAATGGCATACCGATTGGGTAA GTCAGGTGCCAATATCATTCTCTCGGACATTCAAAAAGACAAATTGGACGAAACCGTATCTCTCTTCCAAAAAGAGGGAA TCAAAACCACAGGGATCGTTGCCAATGTGGCCAAAGAAGAAGACAGCATCCGACTGATTGAAGAAGCGGCGGCTTTCCAA GGAAGCCTTGATGTTGCGATCCTCAATGCTGGGATCTTACGGGATGGACTCCTCATCCGCGTAGACAAAGAAACAGGAAA AGTGAAAGGTAAGATGGGTCTTGACCAATGGCAATCGGTGATCGATGTCAATTTAACCGGAGTTTTCCTGACTGGTAGAG AAGCCGCGGCAAAAATGGTCGAACAAAAAAAGGGAGTCATCATCCCCATTGCCTCCATTGCCATGCATGGAAACTCAGGG CAAACCAATTACAGTGCCGCAAAAGCTGGTGTCGCTGCAATGACTGTCACCTGGTCAAAAGAACTCGCTAAATTTGGAAT CAGAGTGGCAGGGATTGCTCCAGGATTCATAGGAACTGAAATGGTTCTAAAAGATATGAACCCAGAAGCTCTTGAAAAGT GGAAGTCCATCATTCCTGTCGGAAGGCTTGGAGAACCAGATGAAATTGCATCCACTGCTGAATTCATTATCACAAACGAT CTTGTGACTGGAGTCGTATTAGAAATCTCTGGTGGTGTCCGAATCTAA
Upstream 100 bases:
>100_bases CGAAGCGCAGAACTTGCGGAAATTTAATTCGTAATTCCACCTCCCCTACTCTCCTAGATTTGTATCGACCTAGTGTCCAC CCTTTTTGAAACTGGTGGAC
Downstream 100 bases:
>100_bases CTTTGATTAGTCCTTTTTTGCCTTCTTTTATAGCACTGAGGGCAAAAAGGGTACGCTCATTGATTCATTATTTTTTTAAC ATTCTGCAAAAATTTCGTAG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 255; Mature: 255
Protein sequence:
>255_residues MELKGANILVTGSAGGLGKAMAYRLGKSGANIILSDIQKDKLDETVSLFQKEGIKTTGIVANVAKEEDSIRLIEEAAAFQ GSLDVAILNAGILRDGLLIRVDKETGKVKGKMGLDQWQSVIDVNLTGVFLTGREAAAKMVEQKKGVIIPIASIAMHGNSG QTNYSAAKAGVAAMTVTWSKELAKFGIRVAGIAPGFIGTEMVLKDMNPEALEKWKSIIPVGRLGEPDEIASTAEFIITND LVTGVVLEISGGVRI
Sequences:
>Translated_255_residues MELKGANILVTGSAGGLGKAMAYRLGKSGANIILSDIQKDKLDETVSLFQKEGIKTTGIVANVAKEEDSIRLIEEAAAFQ GSLDVAILNAGILRDGLLIRVDKETGKVKGKMGLDQWQSVIDVNLTGVFLTGREAAAKMVEQKKGVIIPIASIAMHGNSG QTNYSAAKAGVAAMTVTWSKELAKFGIRVAGIAPGFIGTEMVLKDMNPEALEKWKSIIPVGRLGEPDEIASTAEFIITND LVTGVVLEISGGVRI >Mature_255_residues MELKGANILVTGSAGGLGKAMAYRLGKSGANIILSDIQKDKLDETVSLFQKEGIKTTGIVANVAKEEDSIRLIEEAAAFQ GSLDVAILNAGILRDGLLIRVDKETGKVKGKMGLDQWQSVIDVNLTGVFLTGREAAAKMVEQKKGVIIPIASIAMHGNSG QTNYSAAKAGVAAMTVTWSKELAKFGIRVAGIAPGFIGTEMVLKDMNPEALEKWKSIIPVGRLGEPDEIASTAEFIITND LVTGVVLEISGGVRI
Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=35.2272727272727, Blast_Score=139, Evalue=3e-33, Organism=Homo sapiens, GI40254992, Length=196, Percent_Identity=37.2448979591837, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.9236947791165, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=34.2205323193916, Blast_Score=108, Evalue=3e-24, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=28.6290322580645, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5031737, Length=236, Percent_Identity=28.3898305084746, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=31.6793893129771, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI4504505, Length=221, Percent_Identity=32.579185520362, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=30.2564102564103, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.0546448087432, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=226, Percent_Identity=28.7610619469027, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI209862901, Length=208, Percent_Identity=25, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI19923983, Length=208, Percent_Identity=25, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=25, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI142976729, Length=248, Percent_Identity=23.7903225806452, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI4503301, Length=148, Percent_Identity=30.4054054054054, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=28.0769230769231, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=24.5762711864407, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=34.3629343629344, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=32.046332046332, Blast_Score=124, Evalue=7e-30, Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=31.640625, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=29.0076335877863, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=28.1746031746032, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=27.843137254902, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=29.1187739463602, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=28.1853281853282, Blast_Score=75, Evalue=4e-15, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=34.5238095238095, Blast_Score=127, Evalue=6e-30, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=35.3413654618474, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=28.4, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=33.4600760456274, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562904, Length=248, Percent_Identity=27.0161290322581, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.1937984496124, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=31.3432835820896, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=255, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193203115, Length=222, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=26.2548262548263, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562910, Length=242, Percent_Identity=26.8595041322314, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193203117, Length=223, Percent_Identity=26.9058295964126, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=25.3846153846154, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193204405, Length=245, Percent_Identity=26.9387755102041, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=25.3676470588235, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=26.6129032258064, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=26.2172284644195, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538486, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=24.8062015503876, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=28.3464566929134, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.171875, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561272, Length=151, Percent_Identity=29.8013245033113, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI72000259, Length=253, Percent_Identity=24.901185770751, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=24.124513618677, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=206, Percent_Identity=37.378640776699, Blast_Score=94, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=142, Percent_Identity=32.3943661971831, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=34.8659003831418, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=34.7328244274809, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=28.735632183908, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=28.1368821292776, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=27.9527559055118, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI18859837, Length=229, Percent_Identity=30.1310043668122, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=27.1698113207547, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=25.1231527093596, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24649181, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI221510726, Length=214, Percent_Identity=30.3738317757009, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26879; Mature: 26879
Theoretical pI: Translated: 6.08; Mature: 6.08
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELKGANILVTGSAGGLGKAMAYRLGKSGANIILSDIQKDKLDETVSLFQKEGIKTTGIV CCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHE ANVAKEEDSIRLIEEAAAFQGSLDVAILNAGILRDGLLIRVDKETGKVKGKMGLDQWQSV EEHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCEEEEEECCCCCEECCCCHHHHHHH IDVNLTGVFLTGREAAAKMVEQKKGVIIPIASIAMHGNSGQTNYSAAKAGVAAMTVTWSK EEEEEEEEEEECHHHHHHHHHHHCCEEEEEHHEEEECCCCCCCCHHHHCCEEEEEEEHHH ELAKFGIRVAGIAPGFIGTEMVLKDMNPEALEKWKSIIPVGRLGEPDEIASTAEFIITND HHHHHCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECC LVTGVVLEISGGVRI HHEEEEEEECCCCCC >Mature Secondary Structure MELKGANILVTGSAGGLGKAMAYRLGKSGANIILSDIQKDKLDETVSLFQKEGIKTTGIV CCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHE ANVAKEEDSIRLIEEAAAFQGSLDVAILNAGILRDGLLIRVDKETGKVKGKMGLDQWQSV EEHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCEEEEEECCCCCEECCCCHHHHHHH IDVNLTGVFLTGREAAAKMVEQKKGVIIPIASIAMHGNSGQTNYSAAKAGVAAMTVTWSK EEEEEEEEEEECHHHHHHHHHHHCCEEEEEHHEEEECCCCCCCCHHHHCCEEEEEEEHHH ELAKFGIRVAGIAPGFIGTEMVLKDMNPEALEKWKSIIPVGRLGEPDEIASTAEFIITND HHHHHCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECC LVTGVVLEISGGVRI HHEEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]