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The map label for this gene is xseA [H]

Identifier: 183221244

GI number: 183221244

Start: 1950641

End: 1951936

Strand: Direct

Name: xseA [H]

Synonym: LEPBI_I1860

Alternate gene names: 183221244

Gene position: 1950641-1951936 (Clockwise)

Preceding gene: 183221243

Following gene: 183221245

Centisome position: 54.19

GC content: 41.59

Gene sequence:

>1296_bases
ATGGAAATCGTGGATTCGTCTCTATCCGTAAGCGAAGTCAATCGTCGTATTAAGGCGAAACTCCAAGATGCACCTGAATT
TAAAAACTTTTGGGTGCGCGGAGAAATCTCAAACTACAGCCAAACCAATAGTTCTGGGCATATGTATTTTTCGTTAAAAG
ATACAACAAGTGTCATTAAATGTGCTTTTTTTTCTTACCAAGCCAAAAACTACAAAGGAACTCCTCTCCGCAATGGAATG
GAAATCCTTGTATATGGATCTGTTTCTGTTTATGAACCAGGTGGGTATTATAGTATCACCGTCCAAAAGATTGAAGAATT
GGGGGAAGGAGATATCCTCCTCCGCATTGAAAAACTAAAAAAAACACTCGCCGAAAAAGGAATCTTTGACGCCTCCCACA
AACGGCCGTTACCTAAATTTCCGAAACGATTGGGAATTGTCACCTCTCCCAAAGGTGCAGCCGTGGAAGACATCATTCGT
ATTGCCACAGACCTCAATCCTTCCATCCAAATTTTAGTCTCCCCTTGCCTTGTCCAAGGCGATGGAGCTGAAAACTCAAT
CATCGAAGCCATAAAAGAAATCAATGACCCAAAATGGGAAGTGGATGTGATCATCGCAGGTCGTGGTGGTGGTTCCTTCG
AAGACCTCATGGCGTTTAACCAAGAGTCGGTGGTAATGGCCTATTACCAATCAAGACTCCCCATCATATCGGCTGTGGGT
CATGAAATTGATCGAGTCCTTACCGATCTTGCGGCAGATGCAACAACCCCCACACCCACAGCGGCAGCCAAACTTGCCAT
CCCGAATGTATCGGACACCCTCATCCGTTTGGATGAAATGGAAGATCGATTACGATCTGCACTCACTGGTGTGATTCGAA
TTGGAAAAGAAAAATGGTTTGGTGTGACAAACCGAGCGGTCTTACAAAATCCAAAATCAATTTTGGAACCAAGACAAAAT
CATTTTGATGAAATCATCACCAAAATTTCCTTACTTGGAAAAAACTATTTGGTCAAAAAACAGAGTGAGTTCCAGAAGTT
TGAGGTTTTCCATCAAAACTGGAAATCGTATTTGGAACGAGTACATAATAAATTCCGACTCGCAGAACAACGATTAGATC
ACTTTTCTCCGCTCGGTACCTTAAAACGAGGATACTCAGTCTTGCGGAATACAAACAAACAAGTTATCTCGTCTGTGAAG
CAGATTCAAAAAAATGAAACATTAGAAGTATTTTTATTTGATGGCAAACTGCAAGTGGAAGTGAAAGAAACATTAGGATC
AGAGAATGGTAGATAA

Upstream 100 bases:

>100_bases
TGTTGCAGGGATTATCATTGGACCGATGGCATTAACACTTGTCATCATATTATGGGATTTTTGGAAAATTTTCCGAGAGA
CCCGATTCCAAACTACCTAA

Downstream 100 bases:

>100_bases
AAAAACAATTAGTTTTGAAGAAGCAATCCGTGAATTAGAAGACATTGCCGAAAAGTTAGAACGTGGGACATTGTCCTTGG
AAGATTCTATCAAAGCATAC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MEIVDSSLSVSEVNRRIKAKLQDAPEFKNFWVRGEISNYSQTNSSGHMYFSLKDTTSVIKCAFFSYQAKNYKGTPLRNGM
EILVYGSVSVYEPGGYYSITVQKIEELGEGDILLRIEKLKKTLAEKGIFDASHKRPLPKFPKRLGIVTSPKGAAVEDIIR
IATDLNPSIQILVSPCLVQGDGAENSIIEAIKEINDPKWEVDVIIAGRGGGSFEDLMAFNQESVVMAYYQSRLPIISAVG
HEIDRVLTDLAADATTPTPTAAAKLAIPNVSDTLIRLDEMEDRLRSALTGVIRIGKEKWFGVTNRAVLQNPKSILEPRQN
HFDEIITKISLLGKNYLVKKQSEFQKFEVFHQNWKSYLERVHNKFRLAEQRLDHFSPLGTLKRGYSVLRNTNKQVISSVK
QIQKNETLEVFLFDGKLQVEVKETLGSENGR

Sequences:

>Translated_431_residues
MEIVDSSLSVSEVNRRIKAKLQDAPEFKNFWVRGEISNYSQTNSSGHMYFSLKDTTSVIKCAFFSYQAKNYKGTPLRNGM
EILVYGSVSVYEPGGYYSITVQKIEELGEGDILLRIEKLKKTLAEKGIFDASHKRPLPKFPKRLGIVTSPKGAAVEDIIR
IATDLNPSIQILVSPCLVQGDGAENSIIEAIKEINDPKWEVDVIIAGRGGGSFEDLMAFNQESVVMAYYQSRLPIISAVG
HEIDRVLTDLAADATTPTPTAAAKLAIPNVSDTLIRLDEMEDRLRSALTGVIRIGKEKWFGVTNRAVLQNPKSILEPRQN
HFDEIITKISLLGKNYLVKKQSEFQKFEVFHQNWKSYLERVHNKFRLAEQRLDHFSPLGTLKRGYSVLRNTNKQVISSVK
QIQKNETLEVFLFDGKLQVEVKETLGSENGR
>Mature_431_residues
MEIVDSSLSVSEVNRRIKAKLQDAPEFKNFWVRGEISNYSQTNSSGHMYFSLKDTTSVIKCAFFSYQAKNYKGTPLRNGM
EILVYGSVSVYEPGGYYSITVQKIEELGEGDILLRIEKLKKTLAEKGIFDASHKRPLPKFPKRLGIVTSPKGAAVEDIIR
IATDLNPSIQILVSPCLVQGDGAENSIIEAIKEINDPKWEVDVIIAGRGGGSFEDLMAFNQESVVMAYYQSRLPIISAVG
HEIDRVLTDLAADATTPTPTAAAKLAIPNVSDTLIRLDEMEDRLRSALTGVIRIGKEKWFGVTNRAVLQNPKSILEPRQN
HFDEIITKISLLGKNYLVKKQSEFQKFEVFHQNWKSYLERVHNKFRLAEQRLDHFSPLGTLKRGYSVLRNTNKQVISSVK
QIQKNETLEVFLFDGKLQVEVKETLGSENGR

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=33.9407744874715, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 48486; Mature: 48486

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVDSSLSVSEVNRRIKAKLQDAPEFKNFWVRGEISNYSQTNSSGHMYFSLKDTTSVIK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHCEEEEEECCCCCCCCCCCEEEEEECCHHHHHH
CAFFSYQAKNYKGTPLRNGMEILVYGSVSVYEPGGYYSITVQKIEELGEGDILLRIEKLK
HHHHHHCCCCCCCCCCCCCCEEEEEECEEEECCCCEEEEEHHHHHHCCCCCEEEEHHHHH
KTLAEKGIFDASHKRPLPKFPKRLGIVTSPKGAAVEDIIRIATDLNPSIQILVSPCLVQG
HHHHHCCCCCCCCCCCCCCHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEEEHEEEC
DGAENSIIEAIKEINDPKWEVDVIIAGRGGGSFEDLMAFNQESVVMAYYQSRLPIISAVG
CCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHCCCHHHHHH
HEIDRVLTDLAADATTPTPTAAAKLAIPNVSDTLIRLDEMEDRLRSALTGVIRIGKEKWF
HHHHHHHHHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GVTNRAVLQNPKSILEPRQNHFDEIITKISLLGKNYLVKKQSEFQKFEVFHQNWKSYLER
CCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHH
VHNKFRLAEQRLDHFSPLGTLKRGYSVLRNTNKQVISSVKQIQKNETLEVFLFDGKLQVE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCEEEEE
VKETLGSENGR
EHHHCCCCCCC
>Mature Secondary Structure
MEIVDSSLSVSEVNRRIKAKLQDAPEFKNFWVRGEISNYSQTNSSGHMYFSLKDTTSVIK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHCEEEEEECCCCCCCCCCCEEEEEECCHHHHHH
CAFFSYQAKNYKGTPLRNGMEILVYGSVSVYEPGGYYSITVQKIEELGEGDILLRIEKLK
HHHHHHCCCCCCCCCCCCCCEEEEEECEEEECCCCEEEEEHHHHHHCCCCCEEEEHHHHH
KTLAEKGIFDASHKRPLPKFPKRLGIVTSPKGAAVEDIIRIATDLNPSIQILVSPCLVQG
HHHHHCCCCCCCCCCCCCCHHHHCCCEECCCCCHHHHHHHHHHCCCCCEEEEEEEHEEEC
DGAENSIIEAIKEINDPKWEVDVIIAGRGGGSFEDLMAFNQESVVMAYYQSRLPIISAVG
CCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEHHHHHHCCCHHHHHH
HEIDRVLTDLAADATTPTPTAAAKLAIPNVSDTLIRLDEMEDRLRSALTGVIRIGKEKWF
HHHHHHHHHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GVTNRAVLQNPKSILEPRQNHFDEIITKISLLGKNYLVKKQSEFQKFEVFHQNWKSYLER
CCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHH
VHNKFRLAEQRLDHFSPLGTLKRGYSVLRNTNKQVISSVKQIQKNETLEVFLFDGKLQVE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCEEEEE
VKETLGSENGR
EHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA