Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 183221207

GI number: 183221207

Start: 1904702

End: 1905541

Strand: Reverse

Name: uppP

Synonym: LEPBI_I1821

Alternate gene names: 183221207

Gene position: 1905541-1904702 (Counterclockwise)

Preceding gene: 183221208

Following gene: 183221205

Centisome position: 52.94

GC content: 35.48

Gene sequence:

>840_bases
ATGGATAATACTTTAAACGCTTTTTTACGTGGCATCATCGAAGCTGCCACGGAATTTTTGCCAGTTTCATCCACTGGCCA
TCTGTTTTTATTCAGTTACTTTTTCCCTTTTCAAAATCTATCTGTCCCTCATGAGGCTTTTGAGGACCTATTTGATATTT
TCATTCAAACAGGCGCGATCCTTTCTGTCGTTGTACTCTATTACAAAACTCTTTGGAGTCATTTGGTCGAAGCAGTTCGT
TTTGGATTGGGGAAGTCAACAGATCGCAGTGGGTTTCAATTTTATCTCAATTTAATTGTTGGCATTTTACCAATACTGAT
TCTTGGTTTTTTACTGAAGTCTCAATTAGACCAAATCAAGATGCGATCCGATCTACTTTTGATTTTAGGTATGTCTTGGT
TTGTCGGTGGTATTATCATGGTCTTTGTTGAAAAAAGACATTTGGATGAGAGTAGTGGAAAAACAATCGGTTTTAAGGAA
TCTATCATCGTTGGTTTTTTACAATGTTTTGCTCTGATCCCCGGTGTCTCAAGATCTGCGGCAACCATCATTTCAGCAAG
AACTATGGGAGTTTCGAAAAAAGATAGTGCAGAGTTCTCTTTTTTTCTTGCCATTCCAGTGTTAACTCTCGCAGGCATTT
ATAAATTATACAAACATAGACAAATTTTAAATTCAGAAACAATTGGTTTATTACTTTTCGGTAGTATCATTTCATTTATC
ATCTGTTATTTTATCATACGACTATTTATGGCGTTTATTCGAAGGAGAAGTTTTATTTCCTTTGGAGTTTATCGAATCCT
TTTAGGTCTCCTTGTTATACTTTATTTTGTTCGTTACTGA

Upstream 100 bases:

>100_bases
CATCAAAAGGAATGAAAAATTTGATTTAGATGCATACCTTGCACCAAAGAAAAAAGTAGAAGAACCAGCACCCGCACTTA
CTCCAAATAACTAAGTTTAG

Downstream 100 bases:

>100_bases
GAAATTCTAAATAAAAACTCTTTTTATCAAAGTTTTCTAATCGATTCAATATGTTAAAAAAGAGTTTTTTGTTTTGTTTA
TGGGATTTATTTCTAAGAAA

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDNTLNAFLRGIIEAATEFLPVSSTGHLFLFSYFFPFQNLSVPHEAFEDLFDIFIQTGAILSVVVLYYKTLWSHLVEAVR
FGLGKSTDRSGFQFYLNLIVGILPILILGFLLKSQLDQIKMRSDLLLILGMSWFVGGIIMVFVEKRHLDESSGKTIGFKE
SIIVGFLQCFALIPGVSRSAATIISARTMGVSKKDSAEFSFFLAIPVLTLAGIYKLYKHRQILNSETIGLLLFGSIISFI
ICYFIIRLFMAFIRRRSFISFGVYRILLGLLVILYFVRY

Sequences:

>Translated_279_residues
MDNTLNAFLRGIIEAATEFLPVSSTGHLFLFSYFFPFQNLSVPHEAFEDLFDIFIQTGAILSVVVLYYKTLWSHLVEAVR
FGLGKSTDRSGFQFYLNLIVGILPILILGFLLKSQLDQIKMRSDLLLILGMSWFVGGIIMVFVEKRHLDESSGKTIGFKE
SIIVGFLQCFALIPGVSRSAATIISARTMGVSKKDSAEFSFFLAIPVLTLAGIYKLYKHRQILNSETIGLLLFGSIISFI
ICYFIIRLFMAFIRRRSFISFGVYRILLGLLVILYFVRY
>Mature_279_residues
MDNTLNAFLRGIIEAATEFLPVSSTGHLFLFSYFFPFQNLSVPHEAFEDLFDIFIQTGAILSVVVLYYKTLWSHLVEAVR
FGLGKSTDRSGFQFYLNLIVGILPILILGFLLKSQLDQIKMRSDLLLILGMSWFVGGIIMVFVEKRHLDESSGKTIGFKE
SIIVGFLQCFALIPGVSRSAATIISARTMGVSKKDSAEFSFFLAIPVLTLAGIYKLYKHRQILNSETIGLLLFGSIISFI
ICYFIIRLFMAFIRRRSFISFGVYRILLGLLVILYFVRY

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=285, Percent_Identity=31.9298245614035, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_LEPBA (B0S9E8)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962853.1
- GeneID:   6387741
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1768
- HOGENOM:   HBG391969
- OMA:   VATIPVM
- ProtClustDB:   CLSK574452
- BioCyc:   LBIF355278:LBF_1768-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31616; Mature: 31616

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b0b3ac0)-; HASH(0x1a84b944)-; HASH(0x1b3e3c0c)-; HASH(0x1b971334)-; HASH(0x1b5d2674)-; HASH(0x1b67ed90)-; HASH(0x1aa63920)-; HASH(0x18f98d64)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA