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The map label for this gene is rsbP [H]

Identifier: 183221129

GI number: 183221129

Start: 1818570

End: 1820087

Strand: Reverse

Name: rsbP [H]

Synonym: LEPBI_I1743

Alternate gene names: 183221129

Gene position: 1820087-1818570 (Counterclockwise)

Preceding gene: 183221131

Following gene: 183221128

Centisome position: 50.56

GC content: 38.14

Gene sequence:

>1518_bases
GTGAACAAAAGCAAAATCAAAACGACGAATTCCTTACGCTTTAAGATTGGACTCTTTTATTCTCTCTTAGCCTTTCTCAA
TATCATTTTTTTTACTGTGATGATCTTCGAAAACCAGTCGGATTTGCTCCTAAAAAACTTCCAATTCCAATCTGAAAATT
TAGCAAATACCATTCTAACAGACATTCAGTCGATAGGGCTTTCTCGGGAGAGGGACGAAGGTTTTGAAGTCTTCCGAAAA
ACCTTGAAACTTTATGAAATATCCAAATTTTCCATTTTTGATTCGGAAGGACAGATCATTCATTTGGAACCAGAAGTGGA
AAAAAATGGAGATCCGATCGAGGAATCCGTACTCAAAAAAACAAAGGAAGTATCCTCGGACAAAGAAGGAAATTTATTTA
AGGCACGTTACAGTCTCGAATTGAACGAATCCGATTTTACAGTGAATTTTCTTTTGCCCATCCGACTCTCCGATGGAAAG
GAAGTTTTTTTATACACACATTTTAATATCTCATCCATCCAAGACCGTTTGAAACAACTTTATATCCAAGTTGGGTATGC
AGTGATCTGGGGTGTTTTGTTCCACATTATTTTTGCAATCCTTGTCTATCGTGCTATCTTCAAACGAGTAGGTGATTTAG
AAATTGCTTCCAAGGACATGGCCACTGGCAATTTAGAATCCCGAGTCAATTGGAAATTCAAAAGTGAAGACGAACTCGAC
AGTTTAGGTAAGTCATTCAACCAAATGGCAGAAGAAATTCAAAACAAGGTAACAACGATTACGCGACTAAACCAAGAAAT
CAATCAGGAACTTCAGATTGGAAAGGAAGTTCAGGAATTATTTTTGCCTTCTGTTAAAAAATTCAAAAAATTCAATATTG
GAAAATTATATCGACCCATGCGTGAAGTATCAGGTGACTTATACCAATACTTCCAAGTTCCCGAACAGAATTTTTACGGA
TTCTTTTTGGCAGACGCATCTGGGCATGGAGTGTCTGCAGCACTTGTCACAGTTGTTATGGCAATGTCTTTACAAGCCAT
CATGAAAGAAAGTCCTTCTCCCATCCATGCCATCAATTCGCTTGGGGAAGTGATTGCCAATCGATTACAAGCATCCTTCT
TCGCGACGGGAGTTTTTGTAGTGTTTGATGAGCCTGGTGTGGTTAAATTTGTGAATGCAGGTCATAATGCACCTTTTATC
ATTCGACCTTCTACAAAAGAAGTCCGATTTATCGATAGTTCAGGTCCACCATTAGGTATGGGGGATGATATTCAATATTC
TCTTGATTCCTTTCCTGTGGAACCTGGGGATAAAATCATTCTTTATACTGATGGAGTGGTGGAAACACCGATCAAAGAAG
GTGGACTCTTTGGTTTAGAACGATTTACTGAAATTGTTTTAGAAAATATCCATTTGACGAATGCAGAAATTGTTGAGAAG
GCGATGACCTTACTCGAAGAAAAACATGAAGAGTATAAGGATGATGTTACCATGCTTGTCCTTGATGTACCAGAATGA

Upstream 100 bases:

>100_bases
ACTTCCGAATCTTTGTTATGTAGATCTTTAAAACCAATGGAAAATCTCAATTTTGTGATAGATTTCTATCACTTGATTAT
CGACAATACTAGTAATTGCC

Downstream 100 bases:

>100_bases
AAAAGTTTTTCTTTTTCTCTCTTTTTGGTTTTCTATTTTTGTTCTTTGCTATGGCTTCAGAAGCCATTGTGAGTGTTAAG
TTACAAGAATTACGATTTGG

Product: putative sigma factor sigB regulation protein RsbU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MNKSKIKTTNSLRFKIGLFYSLLAFLNIIFFTVMIFENQSDLLLKNFQFQSENLANTILTDIQSIGLSRERDEGFEVFRK
TLKLYEISKFSIFDSEGQIIHLEPEVEKNGDPIEESVLKKTKEVSSDKEGNLFKARYSLELNESDFTVNFLLPIRLSDGK
EVFLYTHFNISSIQDRLKQLYIQVGYAVIWGVLFHIIFAILVYRAIFKRVGDLEIASKDMATGNLESRVNWKFKSEDELD
SLGKSFNQMAEEIQNKVTTITRLNQEINQELQIGKEVQELFLPSVKKFKKFNIGKLYRPMREVSGDLYQYFQVPEQNFYG
FFLADASGHGVSAALVTVVMAMSLQAIMKESPSPIHAINSLGEVIANRLQASFFATGVFVVFDEPGVVKFVNAGHNAPFI
IRPSTKEVRFIDSSGPPLGMGDDIQYSLDSFPVEPGDKIILYTDGVVETPIKEGGLFGLERFTEIVLENIHLTNAEIVEK
AMTLLEEKHEEYKDDVTMLVLDVPE

Sequences:

>Translated_505_residues
MNKSKIKTTNSLRFKIGLFYSLLAFLNIIFFTVMIFENQSDLLLKNFQFQSENLANTILTDIQSIGLSRERDEGFEVFRK
TLKLYEISKFSIFDSEGQIIHLEPEVEKNGDPIEESVLKKTKEVSSDKEGNLFKARYSLELNESDFTVNFLLPIRLSDGK
EVFLYTHFNISSIQDRLKQLYIQVGYAVIWGVLFHIIFAILVYRAIFKRVGDLEIASKDMATGNLESRVNWKFKSEDELD
SLGKSFNQMAEEIQNKVTTITRLNQEINQELQIGKEVQELFLPSVKKFKKFNIGKLYRPMREVSGDLYQYFQVPEQNFYG
FFLADASGHGVSAALVTVVMAMSLQAIMKESPSPIHAINSLGEVIANRLQASFFATGVFVVFDEPGVVKFVNAGHNAPFI
IRPSTKEVRFIDSSGPPLGMGDDIQYSLDSFPVEPGDKIILYTDGVVETPIKEGGLFGLERFTEIVLENIHLTNAEIVEK
AMTLLEEKHEEYKDDVTMLVLDVPE
>Mature_505_residues
MNKSKIKTTNSLRFKIGLFYSLLAFLNIIFFTVMIFENQSDLLLKNFQFQSENLANTILTDIQSIGLSRERDEGFEVFRK
TLKLYEISKFSIFDSEGQIIHLEPEVEKNGDPIEESVLKKTKEVSSDKEGNLFKARYSLELNESDFTVNFLLPIRLSDGK
EVFLYTHFNISSIQDRLKQLYIQVGYAVIWGVLFHIIFAILVYRAIFKRVGDLEIASKDMATGNLESRVNWKFKSEDELD
SLGKSFNQMAEEIQNKVTTITRLNQEINQELQIGKEVQELFLPSVKKFKKFNIGKLYRPMREVSGDLYQYFQVPEQNFYG
FFLADASGHGVSAALVTVVMAMSLQAIMKESPSPIHAINSLGEVIANRLQASFFATGVFVVFDEPGVVKFVNAGHNAPFI
IRPSTKEVRFIDSSGPPLGMGDDIQYSLDSFPVEPGDKIILYTDGVVETPIKEGGLFGLERFTEIVLENIHLTNAEIVEK
AMTLLEEKHEEYKDDVTMLVLDVPE

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 57419; Mature: 57419

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSKIKTTNSLRFKIGLFYSLLAFLNIIFFTVMIFENQSDLLLKNFQFQSENLANTILT
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHH
DIQSIGLSRERDEGFEVFRKTLKLYEISKFSIFDSEGQIIHLEPEVEKNGDPIEESVLKK
HHHHHCCCCCCHHHHHHHHHHHHHHEECEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
TKEVSSDKEGNLFKARYSLELNESDFTVNFLLPIRLSDGKEVFLYTHFNISSIQDRLKQL
HHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHH
YIQVGYAVIWGVLFHIIFAILVYRAIFKRVGDLEIASKDMATGNLESRVNWKFKSEDELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCHHHH
SLGKSFNQMAEEIQNKVTTITRLNQEINQELQIGKEVQELFLPSVKKFKKFNIGKLYRPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
REVSGDLYQYFQVPEQNFYGFFLADASGHGVSAALVTVVMAMSLQAIMKESPSPIHAINS
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGEVIANRLQASFFATGVFVVFDEPGVVKFVNAGHNAPFIIRPSTKEVRFIDSSGPPLGM
HHHHHHHHHHHHHHHCEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEEECCCCCCCC
GDDIQYSLDSFPVEPGDKIILYTDGVVETPIKEGGLFGLERFTEIVLENIHLTNAEIVEK
CCCCEECCCCCCCCCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
AMTLLEEKHEEYKDDVTMLVLDVPE
HHHHHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MNKSKIKTTNSLRFKIGLFYSLLAFLNIIFFTVMIFENQSDLLLKNFQFQSENLANTILT
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHH
DIQSIGLSRERDEGFEVFRKTLKLYEISKFSIFDSEGQIIHLEPEVEKNGDPIEESVLKK
HHHHHCCCCCCHHHHHHHHHHHHHHEECEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
TKEVSSDKEGNLFKARYSLELNESDFTVNFLLPIRLSDGKEVFLYTHFNISSIQDRLKQL
HHHHCCCCCCCEEEEEEEEEECCCCEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHH
YIQVGYAVIWGVLFHIIFAILVYRAIFKRVGDLEIASKDMATGNLESRVNWKFKSEDELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCHHHH
SLGKSFNQMAEEIQNKVTTITRLNQEINQELQIGKEVQELFLPSVKKFKKFNIGKLYRPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
REVSGDLYQYFQVPEQNFYGFFLADASGHGVSAALVTVVMAMSLQAIMKESPSPIHAINS
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGEVIANRLQASFFATGVFVVFDEPGVVKFVNAGHNAPFIIRPSTKEVRFIDSSGPPLGM
HHHHHHHHHHHHHHHCEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEEECCCCCCCC
GDDIQYSLDSFPVEPGDKIILYTDGVVETPIKEGGLFGLERFTEIVLENIHLTNAEIVEK
CCCCEECCCCCCCCCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
AMTLLEEKHEEYKDDVTMLVLDVPE
HHHHHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]