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The map label for this gene is asnC [H]

Identifier: 183221108

GI number: 183221108

Start: 1793975

End: 1795279

Strand: Reverse

Name: asnC [H]

Synonym: LEPBI_I1722

Alternate gene names: 183221108

Gene position: 1795279-1793975 (Counterclockwise)

Preceding gene: 183221114

Following gene: 183221107

Centisome position: 49.87

GC content: 44.6

Gene sequence:

>1305_bases
ATGATTCCAAGTTTAGAACCAAAAGAGACCCGTCCGTCCCTCTCAAACAATACCCAACCATTAAAAGGTTGGGTGCAAGG
CCTTCGCGGCAATAACCATGTCCAATTTTTGCAACTTCGTACCAATGGAAAAATCTTACAAGTTGTCTGCGAAAAAGAGT
CCTTAGGAGAGGATCTCTTCAAACAAATCAAATCATTGCCCCAAGAAACTTCGATTACGGTTACAGGGAAATGGCAAGAA
AATGCAAAGGCTCCTGGCGGTGAGGAATTGGTTTTGGAATCCTTCCATATCGTTGGTGCCTCATCTGATTACCCCATCAC
ACCAAAAGACCACGGGCCTGATTTTTTACACAACCATAGGCATTTGTGGTTACGATCCAAACGCCAACTTGCCATCCAAA
GGGTACGCTCTGAGTTGTCCTTTGCCATCAGGGAGTTCTTCCGTAACGAAGGTTACACACTCATAGATACCCCCATCCTT
ACAGGCTCGATTGGAGAATCGGCTGGGACTTTATTTTCCACTGAATACTTCGATTTGGGCCAAGCGTACCTGGCCCAGAC
AGGGCAACTTTATTTGGAGACAGCTGCCTTTGCCCATTCCAAGGTATATTGTTTTGGACCGACGTTTCGAGCCGAAAAAA
GTAAAACCAAACGACACCTAACGGAATTTTGGATGTTAGAAGCAGAAACTGCATTTTTGGGACAAGAGGGAAATTTAGAC
CTACAGGAGCGATTCGTGAAATCTGTTCTGACAGTCACGGTCGAACGAACGATAGAGGACTTAAAAACCTTAGAACGAAA
CCCGGAAACTCTGCTTTCTTACCTAAACAAACCGTTTCCACGAGTGGAATACGAAACTGCCATTCAAATCCTAAAAGAAG
CAGGGGAAAGTATCGAATGGGGTGAAGACATCAATGCAGAACGAGAACAAATCCTCACCACTCATTTCGGAACAGCCATC
TTCATTCAAAATTTCCCTCGTGCCATCAAAGCCTTTTATATGAAACAAAATCCAGGTGACCCAAGGACCGTTTTGTCAGC
TGATTTGATAGCTCCAGATGGGATCGGCGAAATCATTGGTGGTTCGGAAAGGGAAGAATCCTATGAAAAAATTGTAGAAC
GTTTACAAGAAGAAGGCCTTCCGCCAGAAGATTATGCCTGGTATCTGGACCTAAGAAAGTATGGTTCTGTACCTCATGCG
GGATTTGGAATGGGTCTGGAACGTGTGATCGCCTGGATCTGTGGATTGCCTCATATTCGGGAGTGTATTCCTTTTCCAAG
GATGATTTACCGTTTGACACCATAA

Upstream 100 bases:

>100_bases
TTTTTCGGAAATCGCTTTACCGTCTAATAGGATGCTAGATTTCATTCTGTAAGTTCAAAATTTCAGAGAAAATTGAACTG
GCAAACAGAAAAAACCATCT

Downstream 100 bases:

>100_bases
TTTTTTTTCGAGGAAAACAAACCATAAGACCGATCTTTTTAAAGAAAGAGAGGTACCTTATGGCACAACAAGCAACCCAA
GTTTTAAACACATCTGTAGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIPSLEPKETRPSLSNNTQPLKGWVQGLRGNNHVQFLQLRTNGKILQVVCEKESLGEDLFKQIKSLPQETSITVTGKWQE
NAKAPGGEELVLESFHIVGASSDYPITPKDHGPDFLHNHRHLWLRSKRQLAIQRVRSELSFAIREFFRNEGYTLIDTPIL
TGSIGESAGTLFSTEYFDLGQAYLAQTGQLYLETAAFAHSKVYCFGPTFRAEKSKTKRHLTEFWMLEAETAFLGQEGNLD
LQERFVKSVLTVTVERTIEDLKTLERNPETLLSYLNKPFPRVEYETAIQILKEAGESIEWGEDINAEREQILTTHFGTAI
FIQNFPRAIKAFYMKQNPGDPRTVLSADLIAPDGIGEIIGGSEREESYEKIVERLQEEGLPPEDYAWYLDLRKYGSVPHA
GFGMGLERVIAWICGLPHIRECIPFPRMIYRLTP

Sequences:

>Translated_434_residues
MIPSLEPKETRPSLSNNTQPLKGWVQGLRGNNHVQFLQLRTNGKILQVVCEKESLGEDLFKQIKSLPQETSITVTGKWQE
NAKAPGGEELVLESFHIVGASSDYPITPKDHGPDFLHNHRHLWLRSKRQLAIQRVRSELSFAIREFFRNEGYTLIDTPIL
TGSIGESAGTLFSTEYFDLGQAYLAQTGQLYLETAAFAHSKVYCFGPTFRAEKSKTKRHLTEFWMLEAETAFLGQEGNLD
LQERFVKSVLTVTVERTIEDLKTLERNPETLLSYLNKPFPRVEYETAIQILKEAGESIEWGEDINAEREQILTTHFGTAI
FIQNFPRAIKAFYMKQNPGDPRTVLSADLIAPDGIGEIIGGSEREESYEKIVERLQEEGLPPEDYAWYLDLRKYGSVPHA
GFGMGLERVIAWICGLPHIRECIPFPRMIYRLTP
>Mature_434_residues
MIPSLEPKETRPSLSNNTQPLKGWVQGLRGNNHVQFLQLRTNGKILQVVCEKESLGEDLFKQIKSLPQETSITVTGKWQE
NAKAPGGEELVLESFHIVGASSDYPITPKDHGPDFLHNHRHLWLRSKRQLAIQRVRSELSFAIREFFRNEGYTLIDTPIL
TGSIGESAGTLFSTEYFDLGQAYLAQTGQLYLETAAFAHSKVYCFGPTFRAEKSKTKRHLTEFWMLEAETAFLGQEGNLD
LQERFVKSVLTVTVERTIEDLKTLERNPETLLSYLNKPFPRVEYETAIQILKEAGESIEWGEDINAEREQILTTHFGTAI
FIQNFPRAIKAFYMKQNPGDPRTVLSADLIAPDGIGEIIGGSEREESYEKIVERLQEEGLPPEDYAWYLDLRKYGSVPHA
GFGMGLERVIAWICGLPHIRECIPFPRMIYRLTP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=436, Percent_Identity=36.0091743119266, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI4758762, Length=428, Percent_Identity=35.0467289719626, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI45439306, Length=334, Percent_Identity=32.3353293413174, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787161, Length=467, Percent_Identity=36.1884368308351, Blast_Score=269, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71984122, Length=437, Percent_Identity=35.4691075514874, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17556372, Length=415, Percent_Identity=31.3253012048193, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17551876, Length=469, Percent_Identity=27.5053304904051, Blast_Score=140, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6321807, Length=428, Percent_Identity=34.5794392523364, Blast_Score=246, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6319872, Length=458, Percent_Identity=32.3144104803493, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6323011, Length=338, Percent_Identity=32.5443786982249, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI19921528, Length=435, Percent_Identity=33.3333333333333, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI19922416, Length=441, Percent_Identity=32.6530612244898, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17136276, Length=459, Percent_Identity=29.1938997821351, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 49378; Mature: 49378

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSLEPKETRPSLSNNTQPLKGWVQGLRGNNHVQFLQLRTNGKILQVVCEKESLGEDLF
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECHHHHHHHHH
KQIKSLPQETSITVTGKWQENAKAPGGEELVLESFHIVGASSDYPITPKDHGPDFLHNHR
HHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHCCC
HLWLRSKRQLAIQRVRSELSFAIREFFRNEGYTLIDTPILTGSIGESAGTLFSTEYFDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEECHHHHHH
QAYLAQTGQLYLETAAFAHSKVYCFGPTFRAEKSKTKRHLTEFWMLEAETAFLGQEGNLD
HHHHHCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LQERFVKSVLTVTVERTIEDLKTLERNPETLLSYLNKPFPRVEYETAIQILKEAGESIEW
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
GEDINAEREQILTTHFGTAIFIQNFPRAIKAFYMKQNPGDPRTVLSADLIAPDGIGEIIG
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHCC
GSEREESYEKIVERLQEEGLPPEDYAWYLDLRKYGSVPHAGFGMGLERVIAWICGLPHIR
CCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHCCCCCCCHHHCHHHHHHHHHCCHHHH
ECIPFPRMIYRLTP
HHCCHHHHHHCCCC
>Mature Secondary Structure
MIPSLEPKETRPSLSNNTQPLKGWVQGLRGNNHVQFLQLRTNGKILQVVCEKESLGEDLF
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECHHHHHHHHH
KQIKSLPQETSITVTGKWQENAKAPGGEELVLESFHIVGASSDYPITPKDHGPDFLHNHR
HHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHCCC
HLWLRSKRQLAIQRVRSELSFAIREFFRNEGYTLIDTPILTGSIGESAGTLFSTEYFDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCEEECHHHHHH
QAYLAQTGQLYLETAAFAHSKVYCFGPTFRAEKSKTKRHLTEFWMLEAETAFLGQEGNLD
HHHHHCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LQERFVKSVLTVTVERTIEDLKTLERNPETLLSYLNKPFPRVEYETAIQILKEAGESIEW
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
GEDINAEREQILTTHFGTAIFIQNFPRAIKAFYMKQNPGDPRTVLSADLIAPDGIGEIIG
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHCC
GSEREESYEKIVERLQEEGLPPEDYAWYLDLRKYGSVPHAGFGMGLERVIAWICGLPHIR
CCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHHHCCCCCCCHHHCHHHHHHHHHCCHHHH
ECIPFPRMIYRLTP
HHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA