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The map label for this gene is 183221075

Identifier: 183221075

GI number: 183221075

Start: 1762234

End: 1763700

Strand: Reverse

Name: 183221075

Synonym: LEPBI_I1688

Alternate gene names: NA

Gene position: 1763700-1762234 (Counterclockwise)

Preceding gene: 183221077

Following gene: 183221073

Centisome position: 49.0

GC content: 41.51

Gene sequence:

>1467_bases
ATGACAACATCAGGTTTTAGAAATCCATCTGTTGTGGTGATCGGTGCTGGAATGACAGGCATTCTTCTAGCGATTGAATT
AGAAAAAGCAGGGATCACCGACATTACCATTTTAGAAAAGAAACATGACTTAGGTGGGACATGGCGAGAGAACACCTATC
CTGGTGTTGCCTGTGATATCCCGGCCCATATGTATACTTATAGTTTTGCGCCAAATCCTGAATGGAGCCATCGTTTTGCC
CATGGTGACGAAATCCAAGCGTACTTCAAACGTGTGAGTGATGAATACAAAGTGACTCCCAAAATCCACTTCAACGAGGC
AGTCACGGAAAGTTCTTATCAGAATGCAAAGTGGACCATCAAAACCTCAAAGGACAAAACCTATGTTTCTGATTTTCTCA
TTTCGGCAACAGGGATCCTGCACCATCCAGCCAAACCAAATATCCCTGGTCTCGAACGTTTCCAAGGAAAATGTTTCCAT
ACAGCGGAATGGGACCATTCTGTTCCTCTCGAAGGGAAACGAATTGGAGTCATTGGAACAGGTTCCACAGCGGCACAAGT
CATTCCGGAAGTGATGAAACTTGGCAAAAAAGTATCTGTATTCCAAAGGACTCCTCAGTGGATTGTAAAAGTACCCGATA
CAACCTACACAGAAGAAGACAAAAAAAAATGGAGGAAGGAACCGAATCTCTTAAAACGATTCCACAAATGGTATACATTT
GCCGTCGAACAAACCTTTTCCAAAGCCGTGATCGGCAAAAAAATTCCTCATATGCTCATGAGTTTTTTATGCAAACGAAA
TCTTCGTACATCTGTAAAAGATCCTGAATTGAGAAAAAAACTAACACCCAACTATCGAGTTGGTTGCAAACGTGTGATTG
TAAATTCTACTTTTTACGATGCCATCCAAAAACCTAACGCAGATCTGGTGACAGAAGGGATAGAAAAAATCACAGAAAAA
GGTGTGGTGACAAAAGATGGTAAACTCCATGAATTGGATGTTTTAGTTCTCGCGACTGGATTCCACCCCTTTCATTTTAT
GCGTCCTATGAATTTAACCGGAGAAAATGGAATCTCCATCGAAACAGCCTGGAAAAAGAAGGTACAAGCATATCGATCAC
TATTTATCCCCCACTTCCCCAATTTTGTTTTAATGTTAGGACCGAACACCCCCATTGGAAATTTTTCTGTCATTGCAATG
AGCGAAGTACAAACCAAATACGTCTTAAAGATCATTGAAGATTGGAGGAGAGGAAAATTCAACTCAATCCAAGCGACAGA
GGAAGCCTTACATCGATTTGCAGCGTATTTGAAAAAAGGAATGGCTGGAACTGTTTGGCTCGGTGGTTGTCAAAGTTGGT
ATTTAGATCCTGATGGAGACCCTGCCATGTGGCCCTATACCTGGAAACAATGGGAAAAGGAAATGAAAACACCTGATTAC
AATGATTTTAGTCTCACCACCCAATAA

Upstream 100 bases:

>100_bases
AAATGTTCAATAATCTGATGTCATTCTCTCTCAGTTGTGTAATACAGAACCATGTTCTCGTAACAATACAAAGTTTGAAA
CATACCGAATGAGGGAACAA

Downstream 100 bases:

>100_bases
ATTATAATCCAAACCTAAACAACATTTTTGCCGGTAGTTTCGAAAGGAATTCCGGCCTTTTTGATTTTAGAATCGTAATA
TAAATTTTAAATATACTGAG

Product: putative flavin-containing monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTTSGFRNPSVVVIGAGMTGILLAIELEKAGITDITILEKKHDLGGTWRENTYPGVACDIPAHMYTYSFAPNPEWSHRFA
HGDEIQAYFKRVSDEYKVTPKIHFNEAVTESSYQNAKWTIKTSKDKTYVSDFLISATGILHHPAKPNIPGLERFQGKCFH
TAEWDHSVPLEGKRIGVIGTGSTAAQVIPEVMKLGKKVSVFQRTPQWIVKVPDTTYTEEDKKKWRKEPNLLKRFHKWYTF
AVEQTFSKAVIGKKIPHMLMSFLCKRNLRTSVKDPELRKKLTPNYRVGCKRVIVNSTFYDAIQKPNADLVTEGIEKITEK
GVVTKDGKLHELDVLVLATGFHPFHFMRPMNLTGENGISIETAWKKKVQAYRSLFIPHFPNFVLMLGPNTPIGNFSVIAM
SEVQTKYVLKIIEDWRRGKFNSIQATEEALHRFAAYLKKGMAGTVWLGGCQSWYLDPDGDPAMWPYTWKQWEKEMKTPDY
NDFSLTTQ

Sequences:

>Translated_488_residues
MTTSGFRNPSVVVIGAGMTGILLAIELEKAGITDITILEKKHDLGGTWRENTYPGVACDIPAHMYTYSFAPNPEWSHRFA
HGDEIQAYFKRVSDEYKVTPKIHFNEAVTESSYQNAKWTIKTSKDKTYVSDFLISATGILHHPAKPNIPGLERFQGKCFH
TAEWDHSVPLEGKRIGVIGTGSTAAQVIPEVMKLGKKVSVFQRTPQWIVKVPDTTYTEEDKKKWRKEPNLLKRFHKWYTF
AVEQTFSKAVIGKKIPHMLMSFLCKRNLRTSVKDPELRKKLTPNYRVGCKRVIVNSTFYDAIQKPNADLVTEGIEKITEK
GVVTKDGKLHELDVLVLATGFHPFHFMRPMNLTGENGISIETAWKKKVQAYRSLFIPHFPNFVLMLGPNTPIGNFSVIAM
SEVQTKYVLKIIEDWRRGKFNSIQATEEALHRFAAYLKKGMAGTVWLGGCQSWYLDPDGDPAMWPYTWKQWEKEMKTPDY
NDFSLTTQ
>Mature_487_residues
TTSGFRNPSVVVIGAGMTGILLAIELEKAGITDITILEKKHDLGGTWRENTYPGVACDIPAHMYTYSFAPNPEWSHRFAH
GDEIQAYFKRVSDEYKVTPKIHFNEAVTESSYQNAKWTIKTSKDKTYVSDFLISATGILHHPAKPNIPGLERFQGKCFHT
AEWDHSVPLEGKRIGVIGTGSTAAQVIPEVMKLGKKVSVFQRTPQWIVKVPDTTYTEEDKKKWRKEPNLLKRFHKWYTFA
VEQTFSKAVIGKKIPHMLMSFLCKRNLRTSVKDPELRKKLTPNYRVGCKRVIVNSTFYDAIQKPNADLVTEGIEKITEKG
VVTKDGKLHELDVLVLATGFHPFHFMRPMNLTGENGISIETAWKKKVQAYRSLFIPHFPNFVLMLGPNTPIGNFSVIAMS
EVQTKYVLKIIEDWRRGKFNSIQATEEALHRFAAYLKKGMAGTVWLGGCQSWYLDPDGDPAMWPYTWKQWEKEMKTPDYN
DFSLTTQ

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=429, Percent_Identity=24.009324009324, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4503755, Length=426, Percent_Identity=22.0657276995305, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI50541965, Length=364, Percent_Identity=24.4505494505494, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI50541961, Length=364, Percent_Identity=24.4505494505494, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4503759, Length=429, Percent_Identity=21.9114219114219, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI221316672, Length=436, Percent_Identity=22.4770642201835, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI221316674, Length=436, Percent_Identity=22.4770642201835, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI221316678, Length=228, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=441, Percent_Identity=23.3560090702948, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25150462, Length=425, Percent_Identity=26.5882352941176, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17555726, Length=452, Percent_Identity=23.8938053097345, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561948, Length=422, Percent_Identity=24.4075829383886, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541300, Length=424, Percent_Identity=24.2924528301887, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922866, Length=210, Percent_Identity=24.7619047619048, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55675; Mature: 55544

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSGFRNPSVVVIGAGMTGILLAIELEKAGITDITILEKKHDLGGTWRENTYPGVACDI
CCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEECC
PAHMYTYSFAPNPEWSHRFAHGDEIQAYFKRVSDEYKVTPKIHFNEAVTESSYQNAKWTI
CHHHEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEECCHHHCCCCCCCCEEEE
KTSKDKTYVSDFLISATGILHHPAKPNIPGLERFQGKCFHTAEWDHSVPLEGKRIGVIGT
EECCCCHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEEEEC
GSTAAQVIPEVMKLGKKVSVFQRTPQWIVKVPDTTYTEEDKKKWRKEPNLLKRFHKWYTF
CCHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
AVEQTFSKAVIGKKIPHMLMSFLCKRNLRTSVKDPELRKKLTPNYRVGCKRVIVNSTFYD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHCCCEEEEECCHHHH
AIQKPNADLVTEGIEKITEKGVVTKDGKLHELDVLVLATGFHPFHFMRPMNLTGENGISI
HHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHCCCCCCCCCCCCEE
ETAWKKKVQAYRSLFIPHFPNFVLMLGPNTPIGNFSVIAMSEVQTKYVLKIIEDWRRGKF
EHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCC
NSIQATEEALHRFAAYLKKGMAGTVWLGGCQSWYLDPDGDPAMWPYTWKQWEKEMKTPDY
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCC
NDFSLTTQ
CCCEEECC
>Mature Secondary Structure 
TTSGFRNPSVVVIGAGMTGILLAIELEKAGITDITILEKKHDLGGTWRENTYPGVACDI
CCCCCCCCCEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCEEECC
PAHMYTYSFAPNPEWSHRFAHGDEIQAYFKRVSDEYKVTPKIHFNEAVTESSYQNAKWTI
CHHHEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEECCHHHCCCCCCCCEEEE
KTSKDKTYVSDFLISATGILHHPAKPNIPGLERFQGKCFHTAEWDHSVPLEGKRIGVIGT
EECCCCHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEEEEC
GSTAAQVIPEVMKLGKKVSVFQRTPQWIVKVPDTTYTEEDKKKWRKEPNLLKRFHKWYTF
CCHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
AVEQTFSKAVIGKKIPHMLMSFLCKRNLRTSVKDPELRKKLTPNYRVGCKRVIVNSTFYD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHCCCEEEEECCHHHH
AIQKPNADLVTEGIEKITEKGVVTKDGKLHELDVLVLATGFHPFHFMRPMNLTGENGISI
HHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHCCCCCCCCCCCCEE
ETAWKKKVQAYRSLFIPHFPNFVLMLGPNTPIGNFSVIAMSEVQTKYVLKIIEDWRRGKF
EHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCC
NSIQATEEALHRFAAYLKKGMAGTVWLGGCQSWYLDPDGDPAMWPYTWKQWEKEMKTPDY
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCC
NDFSLTTQ
CCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]