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The map label for this gene is rpe [H]

Identifier: 183221046

GI number: 183221046

Start: 1735672

End: 1736334

Strand: Direct

Name: rpe [H]

Synonym: LEPBI_I1659

Alternate gene names: 183221046

Gene position: 1735672-1736334 (Clockwise)

Preceding gene: 183221045

Following gene: 183221047

Centisome position: 48.22

GC content: 46.3

Gene sequence:

>663_bases
ATGAAGATTTCAGCCTCTATCCTTGCAGCCAAACTCACGGGACTGGCAACAGAACTCCCTACATACAAAAAGGAAAGTAT
CGATCTCATCCACATAGATGTGATGGATGGCAATTTTGTACCGCAGATTTCCTTTGGAGAAGCCTTCACGAAGGAAGTGA
AGTCTCACACAGATATCCCACTTGATGTCCACCTGATGGTCAGTAACCCGGAACTCCATGTTCCCAAATACTTTGACCTA
AAGCCGTATTGTATCACCTTTCATATTGAAACGACGAATTTTTCGGTACGCCTGGCGGAAGAGATCAAAAAACAAGGGAT
ACGAGTCGGTGTTTCCTTAAACCCGCAGACTCCACCCGAATCCATATCGCAAATCCTTCCATATTTGGACCTTGTGCTCC
TCATGACAGTGGACCCAGGGTTTTACGGGCAGTCCTTTGTGAAGTCGGGATTTGAAAAAATTGCGGCGGTTCGAAAGCTC
ACAAAACCATACGATATTGAACTCGAAGTGGATGGTGGTGTGAACGAATCCAATATGGAAGAACTCGCAAAACTCGGTGT
GGACATCACTGTCGTGGGCTCGGGACTCTATAAAACAGGGGATCCCAATGCTCAGGGCAAAAAATTAAAGGAACTTGCTG
CAAGTGGCCGAACTCGCTCTTGA

Upstream 100 bases:

>100_bases
CTGCGACTTGTGGTCCATCGTTCGACAAATACCAAAGTCACTCTGATAGGAAAAGAAACAGGTGTCGCCAAAGTTTGGAA
ATTAAAAGGAACCTACTAAG

Downstream 100 bases:

>100_bases
CAGAACGTCCCTATTTAAAAAACTCGCTAGAAAAGGGGTATTTTTCCTTGGTTAAATTAAGATTACAAAGAACGGGAACA
AAAGCTGACCCGCATTATCG

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKISASILAAKLTGLATELPTYKKESIDLIHIDVMDGNFVPQISFGEAFTKEVKSHTDIPLDVHLMVSNPELHVPKYFDL
KPYCITFHIETTNFSVRLAEEIKKQGIRVGVSLNPQTPPESISQILPYLDLVLLMTVDPGFYGQSFVKSGFEKIAAVRKL
TKPYDIELEVDGGVNESNMEELAKLGVDITVVGSGLYKTGDPNAQGKKLKELAASGRTRS

Sequences:

>Translated_220_residues
MKISASILAAKLTGLATELPTYKKESIDLIHIDVMDGNFVPQISFGEAFTKEVKSHTDIPLDVHLMVSNPELHVPKYFDL
KPYCITFHIETTNFSVRLAEEIKKQGIRVGVSLNPQTPPESISQILPYLDLVLLMTVDPGFYGQSFVKSGFEKIAAVRKL
TKPYDIELEVDGGVNESNMEELAKLGVDITVVGSGLYKTGDPNAQGKKLKELAASGRTRS
>Mature_220_residues
MKISASILAAKLTGLATELPTYKKESIDLIHIDVMDGNFVPQISFGEAFTKEVKSHTDIPLDVHLMVSNPELHVPKYFDL
KPYCITFHIETTNFSVRLAEEIKKQGIRVGVSLNPQTPPESISQILPYLDLVLLMTVDPGFYGQSFVKSGFEKIAAVRKL
TKPYDIELEVDGGVNESNMEELAKLGVDITVVGSGLYKTGDPNAQGKKLKELAASGRTRS

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=205, Percent_Identity=34.1463414634146, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI219879828, Length=222, Percent_Identity=31.981981981982, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI24307923, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789788, Length=202, Percent_Identity=36.1386138613861, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790523, Length=205, Percent_Identity=35.609756097561, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=29.2452830188679, Blast_Score=94, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=204, Percent_Identity=37.7450980392157, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322341, Length=214, Percent_Identity=31.7757009345794, Blast_Score=126, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24586301, Length=215, Percent_Identity=33.4883720930233, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24195; Mature: 24195

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISASILAAKLTGLATELPTYKKESIDLIHIDVMDGNFVPQISFGEAFTKEVKSHTDIP
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCC
LDVHLMVSNPELHVPKYFDLKPYCITFHIETTNFSVRLAEEIKKQGIRVGVSLNPQTPPE
EEEEEEEECCCEECCEEECCCCEEEEEEEEECCEEEEEHHHHHHCCEEEEEEECCCCCHH
SISQILPYLDLVLLMTVDPGFYGQSFVKSGFEKIAAVRKLTKPYDIELEVDGGVNESNME
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ELAKLGVDITVVGSGLYKTGDPNAQGKKLKELAASGRTRS
HHHHCCCEEEEEECCCEECCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKISASILAAKLTGLATELPTYKKESIDLIHIDVMDGNFVPQISFGEAFTKEVKSHTDIP
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCC
LDVHLMVSNPELHVPKYFDLKPYCITFHIETTNFSVRLAEEIKKQGIRVGVSLNPQTPPE
EEEEEEEECCCEECCEEECCCCEEEEEEEEECCEEEEEHHHHHHCCEEEEEEECCCCCHH
SISQILPYLDLVLLMTVDPGFYGQSFVKSGFEKIAAVRKLTKPYDIELEVDGGVNESNME
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ELAKLGVDITVVGSGLYKTGDPNAQGKKLKELAASGRTRS
HHHHCCCEEEEEECCCEECCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]