| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is pcrA1 [H]
Identifier: 183221021
GI number: 183221021
Start: 1709375
End: 1711558
Strand: Direct
Name: pcrA1 [H]
Synonym: LEPBI_I1634
Alternate gene names: 183221021
Gene position: 1709375-1711558 (Clockwise)
Preceding gene: 183221020
Following gene: 183221022
Centisome position: 47.49
GC content: 36.86
Gene sequence:
>2184_bases GTGGAGTTAGTTGGGCTAAATTCAGAACAAAAACTTGCTGTAGAATCTGTGGATGGACCCCTTCTGATATTGGCAGGAGC GGGTTCAGGAAAAACAAGGGTCATTACCTATCGAATCGCCAATCTCATTCTCAATCATAATGTTTACCCCAACCAAATTT TAGCTGTTACATTTACGAATAAAGCTGCCGAAGAGATGCGTTCCCGTTGTCGCAATCTTTTGCCAGATGGGTCATATGAA CCGTTTGTTCGAACCTTTCACTCTTTGTGTTTGTATCTTTTGAGAAGAGAAGGAAAGGTTTTAGGGTTAGGAAGTAATTT TACTGTTTATGATAGTGATATGCAAGAGTCACTCATCAAAGAAATCCTTAAGTCTAAAGAAATGGACACGAAAGAATTTC GGCCTTCTAGTCTTGCCAATCAGTTTTCCCAAGCGAAAGATTCCTTTTTAACTGCAGAAGAATTTGCGAAAAAAAAAGCT GACGACGCTTATACAAAAACCATAGCTTCCGTATTTTTAGAATATGAAAAACGAAAAAACCTACGGAATGCATTAGATTT TGGAGATTTGATTTTAAAAACAGTCATTCTATTTCGAGATTTCCCGGTCATTCTGGAAAAATACCAGAGGTTATGGAAAT ACATCATGGTAGACGAATACCAAGATACGAACAAAATCCAATACCATTTAGTACAATCTCTCTCCTCCTTTCATAAAAAT TTATGTGTAGTGGGGGATGATGACCAATCAATTTACTCCTGGCGTGGAGCGGATATCTCCAATATCCTAAATTTTAAAAA AGATTACCCTGAAGCGATTGTTGTTAAATTGGAAGAAAACTATCGATCTACCAAAACCATCATTGAATCTGCAGCAGTAT TAATTTCGCATAACAAACAACGTACGAATAAAACTTTACGAACAAAAAATCCTTTAGGTGATAAAATCAAACTCACTTCT TACCAAAATGAAATGGAAGAAGCAGAGGGGATTGTCCAAAGAATCCAAGTTGGTGCGAGGAAAGGTCAAAAATATTCGAA TTTTGCGATTTTTTATCGAACCAATTCGCAATCTAGATATTTTGAAGAAGCACTTCGTAAACGTGCAATCCCTTATAAAA TTTTTGGTGGGTTTCGCTTTTTTGATCGGAAAGAAGTAAAGGATCTCATTGCCTATTTGTCTGTTGTTGTGAATCCAGTT GATTCAACTTCACTCCTTCGTATCATCAATTCTCCTCCAAGAGGGATTGGTGATACAACAGTGAATCGACTTCTGAGTTA TTCTGTTAGGGAAGGAATTTCCTTATTTGAATGTTTGGGAAAAGAAATTCCCGATATTAAAAAGGGTACGGTTCAAAAAT TAAAATCATTGTATCGAATGTTTGAATCTGCAATGGAAGATTTGGGAAAAAAAACTCCCTCCGAAATTGCGTATGATGTT TTGGAACATTCTGGTTATCGTGAATTTTTAGAAAATGAAGGAACAGAAGATTCTTTTTCAAGGTTATCTAACTTAAATGA ATTTGTAAATGCATTGAAAGAATTTGAAGAAGCCAATCCGGAATCAAGTTTAGAAGAATATTTGAGTAGTATTTCACTCA TCACAAGCGAAGAAAACACCAAAGACCTTCCTGATTATGTAATCCTTATGACAGTCCATAATGCAAAAGGACTAGAGTTC CACCATGTTTTTATGGCAGGAATGGAAGAAGGAACCTTCCCTCATTTTTTATCCTTAGATTCCCCTGACGGGATAGAAGA AGAAAGAAGATTGGCATATGTTGCCATCACTCGCGCTCGTAAACATTTAGAGATCAGTTATTCACGTTTCACTCGTAAAT TTGGGGAAGTGGATGCTCGTCTTCCTTCCCAGTTTTTAGAAGAGTTACCAAAAGAATTTTTGGAAGGGGAATTGACCGAA AATAGATTTGGCGTGAGAAGACCCGAAGCCACTCCAAGAGCGGAACGATTTCAAAAATCAGAAGAAAAGTTTGAGTCTGT GCTTGCAAAATCGGGTGATGGTGAGTTCCAGATAGGGACAAAAGTCAGACATAAAGTATACGGAGAAGGGCGTATATTGA GCATTTCTGGTTCTGGTGACAATCGAAAGGTAGAAGTTCGATTTGGTTCTCATTTGGATAAAAAATTCTTATTGGCATAT ACACCATTAGAGATAATATCATAA
Upstream 100 bases:
>100_bases AAGGATCCGTTATACGGGAGTCGAAGATCGGCCTTTTGGTTTGTATCCTGATAATAATAGTTTCCAGTTTGTTTTTGGAA TTGGGGATATGCGATTCTAA
Downstream 100 bases:
>100_bases GGAATTAGGGGTAAGGGCATGAATCTATTTTTTAAGATCTTTTTAATATTCAGTTGTAGTGTAAGTTTTATTTACTCTCA ACAAAACGCTGGTTTGGCGG
Product: ATP-dependent DNA helicase PcrA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 727; Mature: 727
Protein sequence:
>727_residues MELVGLNSEQKLAVESVDGPLLILAGAGSGKTRVITYRIANLILNHNVYPNQILAVTFTNKAAEEMRSRCRNLLPDGSYE PFVRTFHSLCLYLLRREGKVLGLGSNFTVYDSDMQESLIKEILKSKEMDTKEFRPSSLANQFSQAKDSFLTAEEFAKKKA DDAYTKTIASVFLEYEKRKNLRNALDFGDLILKTVILFRDFPVILEKYQRLWKYIMVDEYQDTNKIQYHLVQSLSSFHKN LCVVGDDDQSIYSWRGADISNILNFKKDYPEAIVVKLEENYRSTKTIIESAAVLISHNKQRTNKTLRTKNPLGDKIKLTS YQNEMEEAEGIVQRIQVGARKGQKYSNFAIFYRTNSQSRYFEEALRKRAIPYKIFGGFRFFDRKEVKDLIAYLSVVVNPV DSTSLLRIINSPPRGIGDTTVNRLLSYSVREGISLFECLGKEIPDIKKGTVQKLKSLYRMFESAMEDLGKKTPSEIAYDV LEHSGYREFLENEGTEDSFSRLSNLNEFVNALKEFEEANPESSLEEYLSSISLITSEENTKDLPDYVILMTVHNAKGLEF HHVFMAGMEEGTFPHFLSLDSPDGIEEERRLAYVAITRARKHLEISYSRFTRKFGEVDARLPSQFLEELPKEFLEGELTE NRFGVRRPEATPRAERFQKSEEKFESVLAKSGDGEFQIGTKVRHKVYGEGRILSISGSGDNRKVEVRFGSHLDKKFLLAY TPLEIIS
Sequences:
>Translated_727_residues MELVGLNSEQKLAVESVDGPLLILAGAGSGKTRVITYRIANLILNHNVYPNQILAVTFTNKAAEEMRSRCRNLLPDGSYE PFVRTFHSLCLYLLRREGKVLGLGSNFTVYDSDMQESLIKEILKSKEMDTKEFRPSSLANQFSQAKDSFLTAEEFAKKKA DDAYTKTIASVFLEYEKRKNLRNALDFGDLILKTVILFRDFPVILEKYQRLWKYIMVDEYQDTNKIQYHLVQSLSSFHKN LCVVGDDDQSIYSWRGADISNILNFKKDYPEAIVVKLEENYRSTKTIIESAAVLISHNKQRTNKTLRTKNPLGDKIKLTS YQNEMEEAEGIVQRIQVGARKGQKYSNFAIFYRTNSQSRYFEEALRKRAIPYKIFGGFRFFDRKEVKDLIAYLSVVVNPV DSTSLLRIINSPPRGIGDTTVNRLLSYSVREGISLFECLGKEIPDIKKGTVQKLKSLYRMFESAMEDLGKKTPSEIAYDV LEHSGYREFLENEGTEDSFSRLSNLNEFVNALKEFEEANPESSLEEYLSSISLITSEENTKDLPDYVILMTVHNAKGLEF HHVFMAGMEEGTFPHFLSLDSPDGIEEERRLAYVAITRARKHLEISYSRFTRKFGEVDARLPSQFLEELPKEFLEGELTE NRFGVRRPEATPRAERFQKSEEKFESVLAKSGDGEFQIGTKVRHKVYGEGRILSISGSGDNRKVEVRFGSHLDKKFLLAY TPLEIIS >Mature_727_residues MELVGLNSEQKLAVESVDGPLLILAGAGSGKTRVITYRIANLILNHNVYPNQILAVTFTNKAAEEMRSRCRNLLPDGSYE PFVRTFHSLCLYLLRREGKVLGLGSNFTVYDSDMQESLIKEILKSKEMDTKEFRPSSLANQFSQAKDSFLTAEEFAKKKA DDAYTKTIASVFLEYEKRKNLRNALDFGDLILKTVILFRDFPVILEKYQRLWKYIMVDEYQDTNKIQYHLVQSLSSFHKN LCVVGDDDQSIYSWRGADISNILNFKKDYPEAIVVKLEENYRSTKTIIESAAVLISHNKQRTNKTLRTKNPLGDKIKLTS YQNEMEEAEGIVQRIQVGARKGQKYSNFAIFYRTNSQSRYFEEALRKRAIPYKIFGGFRFFDRKEVKDLIAYLSVVVNPV DSTSLLRIINSPPRGIGDTTVNRLLSYSVREGISLFECLGKEIPDIKKGTVQKLKSLYRMFESAMEDLGKKTPSEIAYDV LEHSGYREFLENEGTEDSFSRLSNLNEFVNALKEFEEANPESSLEEYLSSISLITSEENTKDLPDYVILMTVHNAKGLEF HHVFMAGMEEGTFPHFLSLDSPDGIEEERRLAYVAITRARKHLEISYSRFTRKFGEVDARLPSQFLEELPKEFLEGELTE NRFGVRRPEATPRAERFQKSEEKFESVLAKSGDGEFQIGTKVRHKVYGEGRILSISGSGDNRKVEVRFGSHLDKKFLLAY TPLEIIS
Specific function: Essential helicase [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=731, Percent_Identity=37.0725034199726, Blast_Score=461, Evalue=1e-131, Organism=Escherichia coli, GI48994965, Length=645, Percent_Identity=38.1395348837209, Blast_Score=378, Evalue=1e-106, Organism=Escherichia coli, GI1787196, Length=353, Percent_Identity=30.8781869688385, Blast_Score=112, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6322369, Length=753, Percent_Identity=27.3572377158034, Blast_Score=211, Evalue=4e-55, Organism=Saccharomyces cerevisiae, GI6324477, Length=450, Percent_Identity=24.8888888888889, Blast_Score=86, Evalue=1e-17,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 83323; Mature: 83323
Theoretical pI: Translated: 7.19; Mature: 7.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELVGLNSEQKLAVESVDGPLLILAGAGSGKTRVITYRIANLILNHNVYPNQILAVTFTN CCEECCCCCCCHHHEECCCCEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECC KAAEEMRSRCRNLLPDGSYEPFVRTFHSLCLYLLRREGKVLGLGSNFTVYDSDMQESLIK HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHHHHHH EILKSKEMDTKEFRPSSLANQFSQAKDSFLTAEEFAKKKADDAYTKTIASVFLEYEKRKN HHHHHCCCCCHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH LRNALDFGDLILKTVILFRDFPVILEKYQRLWKYIMVDEYQDTNKIQYHLVQSLSSFHKN HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC LCVVGDDDQSIYSWRGADISNILNFKKDYPEAIVVKLEENYRSTKTIIESAAVLISHNKQ EEEECCCCCCHHEECCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHH RTNKTLRTKNPLGDKIKLTSYQNEMEEAEGIVQRIQVGARKGQKYSNFAIFYRTNSQSRY HHCCHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHH FEEALRKRAIPYKIFGGFRFFDRKEVKDLIAYLSVVVNPVDSTSLLRIINSPPRGIGDTT HHHHHHHCCCCEEEECCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHH VNRLLSYSVREGISLFECLGKEIPDIKKGTVQKLKSLYRMFESAMEDLGKKTPSEIAYDV HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LEHSGYREFLENEGTEDSFSRLSNLNEFVNALKEFEEANPESSLEEYLSSISLITSEENT HHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC KDLPDYVILMTVHNAKGLEFHHVFMAGMEEGTFPHFLSLDSPDGIEEERRLAYVAITRAR CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH KHLEISYSRFTRKFGEVDARLPSQFLEELPKEFLEGELTENRFGVRRPEATPRAERFQKS HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH EEKFESVLAKSGDGEFQIGTKVRHKVYGEGRILSISGSGDNRKVEVRFGSHLDKKFLLAY HHHHHHHHHCCCCCCEEECHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEE TPLEIIS CCHHHCC >Mature Secondary Structure MELVGLNSEQKLAVESVDGPLLILAGAGSGKTRVITYRIANLILNHNVYPNQILAVTFTN CCEECCCCCCCHHHEECCCCEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECC KAAEEMRSRCRNLLPDGSYEPFVRTFHSLCLYLLRREGKVLGLGSNFTVYDSDMQESLIK HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHHHHHH EILKSKEMDTKEFRPSSLANQFSQAKDSFLTAEEFAKKKADDAYTKTIASVFLEYEKRKN HHHHHCCCCCHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH LRNALDFGDLILKTVILFRDFPVILEKYQRLWKYIMVDEYQDTNKIQYHLVQSLSSFHKN HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC LCVVGDDDQSIYSWRGADISNILNFKKDYPEAIVVKLEENYRSTKTIIESAAVLISHNKQ EEEECCCCCCHHEECCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHH RTNKTLRTKNPLGDKIKLTSYQNEMEEAEGIVQRIQVGARKGQKYSNFAIFYRTNSQSRY HHCCHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHH FEEALRKRAIPYKIFGGFRFFDRKEVKDLIAYLSVVVNPVDSTSLLRIINSPPRGIGDTT HHHHHHHCCCCEEEECCCHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHH VNRLLSYSVREGISLFECLGKEIPDIKKGTVQKLKSLYRMFESAMEDLGKKTPSEIAYDV HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LEHSGYREFLENEGTEDSFSRLSNLNEFVNALKEFEEANPESSLEEYLSSISLITSEENT HHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC KDLPDYVILMTVHNAKGLEFHHVFMAGMEEGTFPHFLSLDSPDGIEEERRLAYVAITRAR CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH KHLEISYSRFTRKFGEVDARLPSQFLEELPKEFLEGELTENRFGVRRPEATPRAERFQKS HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH EEKFESVLAKSGDGEFQIGTKVRHKVYGEGRILSISGSGDNRKVEVRFGSHLDKKFLLAY HHHHHHHHHCCCCCCEEECHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEE TPLEIIS CCHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA