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The map label for this gene is yyaP [H]

Identifier: 183220608

GI number: 183220608

Start: 1266086

End: 1266649

Strand: Direct

Name: yyaP [H]

Synonym: LEPBI_I1214

Alternate gene names: 183220608

Gene position: 1266086-1266649 (Clockwise)

Preceding gene: 183220605

Following gene: 183220610

Centisome position: 35.17

GC content: 35.99

Gene sequence:

>564_bases
ATGAGAAAAGTTATTTTTGCAATCAATGCCACAGCTGATGGGTTTTATAGTCACACGGATATGGTGGCTGATGATGATTT
ACACCAATATTTCACCAACATATTAAAGAACGCAGATCAAATTCTCTATGGTAGAACCACCTACCAACTTATGGTTCCTT
TTTGGCCGAATATTGCGAAAGATAAATCTATGTCAAAAGTCAGTAATGAATTCGCAAAAGTTTTCACTTCACTCGAAAAA
ATTTTATTCACAAGAACATTAAAACAAACAGAAGATCCCAATACCAGAATCGCCAAAGATCCGTTAATAGATGAGATCGT
TGTATTAAAGGAAAAACAAGGAAAGGATATCTGTATAGGAAGTTTGAGTTTAGCCTCTCAACTTTCGGAAGCTAACCTCA
TCGATGAATACAGATTTGTCATCCATCCTGTTGTCGCAGGGAACGGACCAAGGTTATTCGAAAATCACAACTTGGAAAAA
TCAGTATCCTTACATTTTGTTAGTTCTGAAAAATTTCCTTCCGGTGCTATGGCACTTCACTACAAAAAACAAGGTAGATT
ATAG

Upstream 100 bases:

>100_bases
TTGATTCAACATCAAAAGTGAAACTGAAAATTTTCCAAAGTGACAAAATATCTGATCAAAATATTCTTTCACACTCAAAC
GAAATCCGTATAACAAGGCC

Downstream 100 bases:

>100_bases
ATATGGAACCATCTGACAAAGTTACAGTAATAATATATTCATTCTTTATAAAAAGTCATACAATTCTTTTAGCAAATAAT
TCAGACTTTTTAAATATCTG

Product: putative dihydrofolate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRKVIFAINATADGFYSHTDMVADDDLHQYFTNILKNADQILYGRTTYQLMVPFWPNIAKDKSMSKVSNEFAKVFTSLEK
ILFTRTLKQTEDPNTRIAKDPLIDEIVVLKEKQGKDICIGSLSLASQLSEANLIDEYRFVIHPVVAGNGPRLFENHNLEK
SVSLHFVSSEKFPSGAMALHYKKQGRL

Sequences:

>Translated_187_residues
MRKVIFAINATADGFYSHTDMVADDDLHQYFTNILKNADQILYGRTTYQLMVPFWPNIAKDKSMSKVSNEFAKVFTSLEK
ILFTRTLKQTEDPNTRIAKDPLIDEIVVLKEKQGKDICIGSLSLASQLSEANLIDEYRFVIHPVVAGNGPRLFENHNLEK
SVSLHFVSSEKFPSGAMALHYKKQGRL
>Mature_187_residues
MRKVIFAINATADGFYSHTDMVADDDLHQYFTNILKNADQILYGRTTYQLMVPFWPNIAKDKSMSKVSNEFAKVFTSLEK
ILFTRTLKQTEDPNTRIAKDPLIDEIVVLKEKQGKDICIGSLSLASQLSEANLIDEYRFVIHPVVAGNGPRLFENHNLEK
SVSLHFVSSEKFPSGAMALHYKKQGRL

Specific function: Unknown

COG id: COG0262

COG function: function code H; Dihydrofolate reductase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywjB [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: NA

Molecular weight: Translated: 21227; Mature: 21227

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVIFAINATADGFYSHTDMVADDDLHQYFTNILKNADQILYGRTTYQLMVPFWPNIAK
CCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCEEEEEECCCCCCCC
DKSMSKVSNEFAKVFTSLEKILFTRTLKQTEDPNTRIAKDPLIDEIVVLKEKQGKDICIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEEECCCCCEEEEE
SLSLASQLSEANLIDEYRFVIHPVVAGNGPRLFENHNLEKSVSLHFVSSEKFPSGAMALH
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCEEEE
YKKQGRL
EECCCCC
>Mature Secondary Structure
MRKVIFAINATADGFYSHTDMVADDDLHQYFTNILKNADQILYGRTTYQLMVPFWPNIAK
CCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHEEECCCEEEEEECCCCCCCC
DKSMSKVSNEFAKVFTSLEKILFTRTLKQTEDPNTRIAKDPLIDEIVVLKEKQGKDICIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHEEECCCCCEEEEE
SLSLASQLSEANLIDEYRFVIHPVVAGNGPRLFENHNLEKSVSLHFVSSEKFPSGAMALH
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCEEEE
YKKQGRL
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]