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The map label for this gene is msrB [H]

Identifier: 183220568

GI number: 183220568

Start: 1221363

End: 1221743

Strand: Direct

Name: msrB [H]

Synonym: LEPBI_I1172

Alternate gene names: 183220568

Gene position: 1221363-1221743 (Clockwise)

Preceding gene: 183220560

Following gene: 183220573

Centisome position: 33.93

GC content: 44.62

Gene sequence:

>381_bases
ATGGAAAACAAAAATTGGAAAGAAATCCTCACACCATTACAATACCAAGTGACTCGTGAAAAGGGCACCGAACGGCCGTT
TACTGGTGAATACTATGCACACAAAGAAAAAGGAACTTATCTTTGTGTTTGTTGTGGAGAGGCTTTGTTTTCTTCCGAGA
CGAAATATGAGTCAGGGAGTGGTTGGCCTAGTTATTATGAACCGGTTCGTTCAGATGCAGTGTCCACTGAAACGGATCGA
TCCCATGGAATGACGAGAACCGAAATCCAGTGCCAAAATTGTGGTGCTCACTTGGGCCATGTGTTCCCAGACGGTCCGAA
GCCAACGGGACTCCGATATTGTGTGAACTCCGCTTCTCTCAAATTTCAAAAATCCGAATAA

Upstream 100 bases:

>100_bases
CTATCAAATACATCGTTGTAACTGTCACAAGATTGTCAGTTCCTAAAAAAATAAAATGTGATATTGATACTTAATCTCAA
TTAGAAAGGCGAAGGAAAGA

Downstream 100 bases:

>100_bases
GAGAAAAAAGCATCGAACGTTTTGTACGAAAGTGGTCATCTTACGAACGGGAAAATTCACATCGAAGTAAACTTTCATCA
AAGGAAATGTTTCCTTTGAT

Product: peptide methionine sulfoxide reductase MsrB

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MENKNWKEILTPLQYQVTREKGTERPFTGEYYAHKEKGTYLCVCCGEALFSSETKYESGSGWPSYYEPVRSDAVSTETDR
SHGMTRTEIQCQNCGAHLGHVFPDGPKPTGLRYCVNSASLKFQKSE

Sequences:

>Translated_126_residues
MENKNWKEILTPLQYQVTREKGTERPFTGEYYAHKEKGTYLCVCCGEALFSSETKYESGSGWPSYYEPVRSDAVSTETDR
SHGMTRTEIQCQNCGAHLGHVFPDGPKPTGLRYCVNSASLKFQKSE
>Mature_126_residues
MENKNWKEILTPLQYQVTREKGTERPFTGEYYAHKEKGTYLCVCCGEALFSSETKYESGSGWPSYYEPVRSDAVSTETDR
SHGMTRTEIQCQNCGAHLGHVFPDGPKPTGLRYCVNSASLKFQKSE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=54.7619047619048, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=54.7619047619048, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=54.7619047619048, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI37620216, Length=126, Percent_Identity=54.7619047619048, Blast_Score=156, Evalue=4e-39,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=51.5384615384615, Blast_Score=137, Evalue=2e-33,
Organism=Homo sapiens, GI7706511, Length=100, Percent_Identity=43, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788077, Length=120, Percent_Identity=57.5, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17553450, Length=123, Percent_Identity=52.8455284552846, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115532676, Length=123, Percent_Identity=52.8455284552846, Blast_Score=139, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319816, Length=126, Percent_Identity=46.031746031746, Blast_Score=112, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=53.1746031746032, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI221378662, Length=133, Percent_Identity=49.6240601503759, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=51.9685039370079, Blast_Score=141, Evalue=9e-35,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=51.9685039370079, Blast_Score=140, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=51.9685039370079, Blast_Score=140, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=47.8260869565217, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=47.8260869565217, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14272; Mature: 14272

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKNWKEILTPLQYQVTREKGTERPFTGEYYAHKEKGTYLCVCCGEALFSSETKYESGS
CCCCCHHHHHCHHHEEEECCCCCCCCCCCCEEEECCCCCEEEEECCCHHHCCCCCCCCCC
GWPSYYEPVRSDAVSTETDRSHGMTRTEIQCQNCGAHLGHVFPDGPKPTGLRYCVNSASL
CCCHHHHHHHHCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCE
KFQKSE
EEECCC
>Mature Secondary Structure
MENKNWKEILTPLQYQVTREKGTERPFTGEYYAHKEKGTYLCVCCGEALFSSETKYESGS
CCCCCHHHHHCHHHEEEECCCCCCCCCCCCEEEECCCCCEEEEECCCHHHCCCCCCCCCC
GWPSYYEPVRSDAVSTETDRSHGMTRTEIQCQNCGAHLGHVFPDGPKPTGLRYCVNSASL
CCCHHHHHHHHCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCE
KFQKSE
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA