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The map label for this gene is pdtaS [H]

Identifier: 183220512

GI number: 183220512

Start: 1161295

End: 1162536

Strand: Direct

Name: pdtaS [H]

Synonym: LEPBI_I1113

Alternate gene names: 183220512

Gene position: 1161295-1162536 (Clockwise)

Preceding gene: 183220511

Following gene: 183220513

Centisome position: 32.26

GC content: 34.7

Gene sequence:

>1242_bases
GTGAAAGCAGCCGCCCGAATTGCAATTTTTTATCTGTTTTTCGGGTATCTGTGGATTTACTTTTCAGACTACACTATCTC
TATTTTCTTTTTGTCTGCTGAAGATACGAGAGAGATCCAAAGTTTTAAAGGATGGGGATTTGTCACCATCTCCGCCTTTA
TCATTTATTTTTTACTCGTTCGTGAATTAAAATACCAGAAGAAAGTTTTATCAGAAAAATTTGAATCGGATCAATTATTC
CAAGTGATCCTCGAACGAATTGAAGATGCAGTCATCGTATTCAATTTAGATACTTGGAAAATAGATTTTTTAAGCGAACA
AGTATGTCGATTGTTTGACATCAATACCAAGGACATCCTTGCCAATCCCCAGTTACTGATTGATCGTGTTTTTGAAGCCG
ACAGACATCGTATGTCTGATATTTGGATGAACAAATTGCGAGAAAATCATACTGGATTACTCTATCGAATTCAAATGTTA
GATGGGAAAATCAAATGGGCATTGGAACATAGGTTATTCATTCCTTCCAGAAATGGTACGCCAAACAAGGCAGTCGCAGT
GATTTCGGATATGACCAGTTATATGGAAAACCAAACCAAACTGGAACAATCATTAAAAGAAAATGAAACATTACTAACTG
AAGTGCATCACCGAGTCAAAAATAACTTAGCTGTGATCATTTCGTTTTTACAACTACAAGTTTATTCTTCACCACCTGAA
ACTGCTGATATATTAGAACAAAGTATTGTAAGAATCAAAGCAATTGCACTAGTTCATGAGAAGTTGTACAGTGGGAAAAA
TTTATCTGGTTTGAGTTCGGTAGATTATATCACAAGCCTAGTTGAAAATATTAAACTTATGTATATGAGATCCGATATCC
AAATTGAGTTGGATATCCAAACGATGGAATTTAATATTATTGATGCGATCCCTATGGGACTTATGATTACAGAGATGTTA
ACTAATAGTTTCAGGCACGCATTTAAAATTCCAAAATCCGATGCCCAGATTAAAATCGAATTCATTGTGAAAGAGAGTGG
TCAATTTGATTTGAAATACCGAGACAATGGAATTGGATTTCCGATTGGTTTTGATTATCGAAAGGCAGAATCGATTGGAT
TATCAGTGATTTTTTCACTCAGTAGCCAATTGAATGGTCGCGAAATTGAATGTACTTCAATTCCCAATCAAGGTGTGTTT
TATCATTTTTCATTTGCACCCAAAAGAACAAATTCTAAATAA

Upstream 100 bases:

>100_bases
AGAGTTAGCGGATTTGTGGAATCATTATACACAACTGAGTACCTCCATCGAAGAGATGGTTCATACTCGCTATAGTTCAC
TCCAGGAGTTCGCCTAAATT

Downstream 100 bases:

>100_bases
AAAAATCATTGTAGGTCATTATGTATACGAAAGGTAAAAATTTTTCAGAAATCCAAATGGGAGAAAAGGCTTCTTTTACA
AAAACTATTTCTGAATCAGA

Product: putative two-component sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKAAARIAIFYLFFGYLWIYFSDYTISIFFLSAEDTREIQSFKGWGFVTISAFIIYFLLVRELKYQKKVLSEKFESDQLF
QVILERIEDAVIVFNLDTWKIDFLSEQVCRLFDINTKDILANPQLLIDRVFEADRHRMSDIWMNKLRENHTGLLYRIQML
DGKIKWALEHRLFIPSRNGTPNKAVAVISDMTSYMENQTKLEQSLKENETLLTEVHHRVKNNLAVIISFLQLQVYSSPPE
TADILEQSIVRIKAIALVHEKLYSGKNLSGLSSVDYITSLVENIKLMYMRSDIQIELDIQTMEFNIIDAIPMGLMITEML
TNSFRHAFKIPKSDAQIKIEFIVKESGQFDLKYRDNGIGFPIGFDYRKAESIGLSVIFSLSSQLNGREIECTSIPNQGVF
YHFSFAPKRTNSK

Sequences:

>Translated_413_residues
MKAAARIAIFYLFFGYLWIYFSDYTISIFFLSAEDTREIQSFKGWGFVTISAFIIYFLLVRELKYQKKVLSEKFESDQLF
QVILERIEDAVIVFNLDTWKIDFLSEQVCRLFDINTKDILANPQLLIDRVFEADRHRMSDIWMNKLRENHTGLLYRIQML
DGKIKWALEHRLFIPSRNGTPNKAVAVISDMTSYMENQTKLEQSLKENETLLTEVHHRVKNNLAVIISFLQLQVYSSPPE
TADILEQSIVRIKAIALVHEKLYSGKNLSGLSSVDYITSLVENIKLMYMRSDIQIELDIQTMEFNIIDAIPMGLMITEML
TNSFRHAFKIPKSDAQIKIEFIVKESGQFDLKYRDNGIGFPIGFDYRKAESIGLSVIFSLSSQLNGREIECTSIPNQGVF
YHFSFAPKRTNSK
>Mature_413_residues
MKAAARIAIFYLFFGYLWIYFSDYTISIFFLSAEDTREIQSFKGWGFVTISAFIIYFLLVRELKYQKKVLSEKFESDQLF
QVILERIEDAVIVFNLDTWKIDFLSEQVCRLFDINTKDILANPQLLIDRVFEADRHRMSDIWMNKLRENHTGLLYRIQML
DGKIKWALEHRLFIPSRNGTPNKAVAVISDMTSYMENQTKLEQSLKENETLLTEVHHRVKNNLAVIISFLQLQVYSSPPE
TADILEQSIVRIKAIALVHEKLYSGKNLSGLSSVDYITSLVENIKLMYMRSDIQIELDIQTMEFNIIDAIPMGLMITEML
TNSFRHAFKIPKSDAQIKIEFIVKESGQFDLKYRDNGIGFPIGFDYRKAESIGLSVIFSLSSQLNGREIECTSIPNQGVF
YHFSFAPKRTNSK

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47946; Mature: 47946

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAARIAIFYLFFGYLWIYFSDYTISIFFLSAEDTREIQSFKGWGFVTISAFIIYFLLV
CCCHHHHHHHHHHHHHHHHHEECEEEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHH
RELKYQKKVLSEKFESDQLFQVILERIEDAVIVFNLDTWKIDFLSEQVCRLFDINTKDIL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHCCCCHHHH
ANPQLLIDRVFEADRHRMSDIWMNKLRENHTGLLYRIQMLDGKIKWALEHRLFIPSRNGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEEEEEEECCCCC
PNKAVAVISDMTSYMENQTKLEQSLKENETLLTEVHHRVKNNLAVIISFLQLQVYSSPPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCC
TADILEQSIVRIKAIALVHEKLYSGKNLSGLSSVDYITSLVENIKLMYMRSDIQIELDIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEECCEEEEEEEE
TMEFNIIDAIPMGLMITEMLTNSFRHAFKIPKSDAQIKIEFIVKESGQFDLKYRDNGIGF
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEECCCCCCC
PIGFDYRKAESIGLSVIFSLSSQLNGREIECTSIPNQGVFYHFSFAPKRTNSK
CCCCCCHHHHHCCHHHEEEHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MKAAARIAIFYLFFGYLWIYFSDYTISIFFLSAEDTREIQSFKGWGFVTISAFIIYFLLV
CCCHHHHHHHHHHHHHHHHHEECEEEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHH
RELKYQKKVLSEKFESDQLFQVILERIEDAVIVFNLDTWKIDFLSEQVCRLFDINTKDIL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHCCCCHHHH
ANPQLLIDRVFEADRHRMSDIWMNKLRENHTGLLYRIQMLDGKIKWALEHRLFIPSRNGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEEEEEEECCCCC
PNKAVAVISDMTSYMENQTKLEQSLKENETLLTEVHHRVKNNLAVIISFLQLQVYSSPPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCC
TADILEQSIVRIKAIALVHEKLYSGKNLSGLSSVDYITSLVENIKLMYMRSDIQIELDIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEECCEEEEEEEE
TMEFNIIDAIPMGLMITEMLTNSFRHAFKIPKSDAQIKIEFIVKESGQFDLKYRDNGIGF
EEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEECCCCCCC
PIGFDYRKAESIGLSVIFSLSSQLNGREIECTSIPNQGVFYHFSFAPKRTNSK
CCCCCCHHHHHCCHHHEEEHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]