| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is mrcA [H]
Identifier: 183220414
GI number: 183220414
Start: 1055416
End: 1057839
Strand: Direct
Name: mrcA [H]
Synonym: LEPBI_I1010
Alternate gene names: 183220414
Gene position: 1055416-1057839 (Clockwise)
Preceding gene: 183220413
Following gene: 183220415
Centisome position: 29.32
GC content: 43.11
Gene sequence:
>2424_bases ATGACTATGAACAAAGAAAAAACACTACGTATCACCATCACAACATTCTTTAGTATTGCCTTATTTGGTGGACTTTTTTT TGGATACATCCTTTCCGAAGTGAACAAAGGAAAAGAACTTCAAAAGCTTGCATCCTATCAGCCCACAACACCAACAAAAC TTTATGATACCAATGGAATCCTAGTTGCGGAACTTTACCGTCACAAACAAGAATTATTAAAATACAGTGACATCCCTCCA CATGTGATCCATGCCTTTTTATCAGTTGAGGATGATAACTTTTTTAACCACTTTGGAATTGATTTTTTGGCAATTGTACG CGCTGCGATTAAAAATATATTCGCAGGACGGATCGTCCAAGGTGGATCCACATTAACCCAACAGTTAGCAAAAACCATTC TGCAACAAAGGAAAAAAACCTTTGGACGTAAATTCTTAGAAGCGCTTCTCACTCTGCAAATTGAACAAGAATATACCAAA GAAGAAATTTTGGAAATTTACTTTAACCTCATTTATTTGGGACATGGAACCACTGGTTTGTCTTCTGCGGCTAATGTTTA TTTCCAAAAAGATGTCAGGGACCTAAGCATTGCAGAAGCAGCAATGCTTGCCCGTTTGCCGAAAGCCCCTGTAACCTATT CTCCTTTTAAAAATCCCAAAGAAGCCAAACAAGCGCATATGGTAGTGCTTGGACTTATGGCAAAGAATGGATTCATCCCT AAAGACCAAGTGCAAAAGATCCATGATGATTTTTGGGATCGTTATTGGCCTGTTGTCATCACACAATCTCCGTCTCGTTC CACTTGGGGTGCCAAACTCAATAGAGCTCCTTATTTTACAGAGTGGGTGCGCCAAATCCTAGAAAAGGAATTGGGCGAAG AAGCGTTGTACACAGGTGGTTTACGAGTGTATACCACTCTAGATGTGAGAAAACAAGAAATTTCAGAAGAAGAACTTCGA AAAGGCCTAATCGAACAAGATAAATATGCTTTTGGAGCAAACTTTCGTTATGCGGGACGGGCGGATCGAGGCCTCGTTTC TTTATACAATTTGTTTAGTTCTATTTTCCCTGTGGGTGTGCCGTATGTGACAAGCCTTGATGACAGGCAAGTTTTCCGTT TGCATTTGGAAAAAGAAATGGCACCCGCTCTCGAACTATTAACAGACTTTGTGCCTTCGGAAAACGAAAGTGCGGCTGTT AAAGAATTCCAAAGGTCGTCTCTTGTGTTTTCCTCCAACTTACACGTAGAAGGTGCAGTGATTACCATTGACCACCAAAC AGGATACATCCAAACCATGGTAGGAGGATCTCGATTTTCTCCTAAAAACCAATTCAACCGCGCCATGCAAGCAAGACGCC AAACCGGTTCCGCTTTCAAACCGTTTGTGTATGCAGCGGCCATCCAAAACAGGGCCGTTGGTTCGGGAACGGGGATTATG GATGCTCCACTCACAACGATTACAGAAGAAGGGGAGGGATATTCTCCTCAAGATATCTCCGGCGACTTCCGTGGGATGGT ACCTTTATCGCGTGCCTTATCTTTATCACTCAATATTGTTTCAGTGCAAGTTCTCATGAGAACTGGGACGGACTCCGTCA TTGATTTTGCTTCAAAAGTCACCAAAACAAATAAATCTCGTTTCCCAACGGGACCTGCCCTGGCACTTGGTGTGGCAGAA CTCACTCCTTATGAAATGGCACTTGGGTATTCGATTCTTGCCAACAAAGGAAAGGATGTGATTCCATTTAGCGTTCGTTA TGTATTAAACCAAAGTGGAACGGTGGTTTATAATAAGGAAAAAGAGGTCCAAGAAACTTTGGCTGAAGAAGCAAAAAACG GGACCATTCAAATCATTCCCGAAGCCACAGCATATATCATAAAACAAATGTTAATTGGTGTGGCTATGGGGGGAACTCCC ACCCAAGCTTTACGTGCAGCGGACAAGGGGAATTACAAAGGGGAATCAGGTGGTAAAACAGGATCCACTTCTTCCTATAC CAATGTTTGGTATGCTGGTTTTGACCCGAAATACACTTCTATCGTATGGATGGGATTTGATAAATCGTCTCTATCCTTAG GAAAAGGTGTGACCGCTGCGGGAGTTGCCGCTCCGATTTGGGGTAAGATGTATTCTCGGTTTTATAATGAAGGACCTTAC CCAAGTTTTTATCCCAATGGAAAATCGGAAGAGATCCCAGCAGATGTGGTCAAAGGCGCAACCTGTGCCTTCAACGGACT GTCTCCTGGACCCAATTGCCCTCTCACGGGAAATTTATTCCTAAAACCCATTACCATTGCTGGTCGGACTTTGGCCGTTC CTGGGGGAAGGCAGTGTGATGGAGACAGGGACCATTACCGCTCTATGGACTTAAATGATTTCTTGCAGAGAGAGTTGGAA ATTTCCGACGACGAGCTCAAATAA
Upstream 100 bases:
>100_bases TTTATGAAATATATGAAAGTGCCAAATTGCACAAACAGCAATTAGGCGAAAAGAAATTAAAAATTCATTTAGCAAGAGAA GGACTAAGGTTCCACCTATA
Downstream 100 bases:
>100_bases ATTCGACCCAAAATCAAACGAGGATTGGAGTGAATCGCCTCCTCCCATCCCCGGTGCAAATCGGCATCTCATTCCCCATC TCTCACGGATGGGAACCAAT
Product: putative penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 807; Mature: 806
Protein sequence:
>807_residues MTMNKEKTLRITITTFFSIALFGGLFFGYILSEVNKGKELQKLASYQPTTPTKLYDTNGILVAELYRHKQELLKYSDIPP HVIHAFLSVEDDNFFNHFGIDFLAIVRAAIKNIFAGRIVQGGSTLTQQLAKTILQQRKKTFGRKFLEALLTLQIEQEYTK EEILEIYFNLIYLGHGTTGLSSAANVYFQKDVRDLSIAEAAMLARLPKAPVTYSPFKNPKEAKQAHMVVLGLMAKNGFIP KDQVQKIHDDFWDRYWPVVITQSPSRSTWGAKLNRAPYFTEWVRQILEKELGEEALYTGGLRVYTTLDVRKQEISEEELR KGLIEQDKYAFGANFRYAGRADRGLVSLYNLFSSIFPVGVPYVTSLDDRQVFRLHLEKEMAPALELLTDFVPSENESAAV KEFQRSSLVFSSNLHVEGAVITIDHQTGYIQTMVGGSRFSPKNQFNRAMQARRQTGSAFKPFVYAAAIQNRAVGSGTGIM DAPLTTITEEGEGYSPQDISGDFRGMVPLSRALSLSLNIVSVQVLMRTGTDSVIDFASKVTKTNKSRFPTGPALALGVAE LTPYEMALGYSILANKGKDVIPFSVRYVLNQSGTVVYNKEKEVQETLAEEAKNGTIQIIPEATAYIIKQMLIGVAMGGTP TQALRAADKGNYKGESGGKTGSTSSYTNVWYAGFDPKYTSIVWMGFDKSSLSLGKGVTAAGVAAPIWGKMYSRFYNEGPY PSFYPNGKSEEIPADVVKGATCAFNGLSPGPNCPLTGNLFLKPITIAGRTLAVPGGRQCDGDRDHYRSMDLNDFLQRELE ISDDELK
Sequences:
>Translated_807_residues MTMNKEKTLRITITTFFSIALFGGLFFGYILSEVNKGKELQKLASYQPTTPTKLYDTNGILVAELYRHKQELLKYSDIPP HVIHAFLSVEDDNFFNHFGIDFLAIVRAAIKNIFAGRIVQGGSTLTQQLAKTILQQRKKTFGRKFLEALLTLQIEQEYTK EEILEIYFNLIYLGHGTTGLSSAANVYFQKDVRDLSIAEAAMLARLPKAPVTYSPFKNPKEAKQAHMVVLGLMAKNGFIP KDQVQKIHDDFWDRYWPVVITQSPSRSTWGAKLNRAPYFTEWVRQILEKELGEEALYTGGLRVYTTLDVRKQEISEEELR KGLIEQDKYAFGANFRYAGRADRGLVSLYNLFSSIFPVGVPYVTSLDDRQVFRLHLEKEMAPALELLTDFVPSENESAAV KEFQRSSLVFSSNLHVEGAVITIDHQTGYIQTMVGGSRFSPKNQFNRAMQARRQTGSAFKPFVYAAAIQNRAVGSGTGIM DAPLTTITEEGEGYSPQDISGDFRGMVPLSRALSLSLNIVSVQVLMRTGTDSVIDFASKVTKTNKSRFPTGPALALGVAE LTPYEMALGYSILANKGKDVIPFSVRYVLNQSGTVVYNKEKEVQETLAEEAKNGTIQIIPEATAYIIKQMLIGVAMGGTP TQALRAADKGNYKGESGGKTGSTSSYTNVWYAGFDPKYTSIVWMGFDKSSLSLGKGVTAAGVAAPIWGKMYSRFYNEGPY PSFYPNGKSEEIPADVVKGATCAFNGLSPGPNCPLTGNLFLKPITIAGRTLAVPGGRQCDGDRDHYRSMDLNDFLQRELE ISDDELK >Mature_806_residues TMNKEKTLRITITTFFSIALFGGLFFGYILSEVNKGKELQKLASYQPTTPTKLYDTNGILVAELYRHKQELLKYSDIPPH VIHAFLSVEDDNFFNHFGIDFLAIVRAAIKNIFAGRIVQGGSTLTQQLAKTILQQRKKTFGRKFLEALLTLQIEQEYTKE EILEIYFNLIYLGHGTTGLSSAANVYFQKDVRDLSIAEAAMLARLPKAPVTYSPFKNPKEAKQAHMVVLGLMAKNGFIPK DQVQKIHDDFWDRYWPVVITQSPSRSTWGAKLNRAPYFTEWVRQILEKELGEEALYTGGLRVYTTLDVRKQEISEEELRK GLIEQDKYAFGANFRYAGRADRGLVSLYNLFSSIFPVGVPYVTSLDDRQVFRLHLEKEMAPALELLTDFVPSENESAAVK EFQRSSLVFSSNLHVEGAVITIDHQTGYIQTMVGGSRFSPKNQFNRAMQARRQTGSAFKPFVYAAAIQNRAVGSGTGIMD APLTTITEEGEGYSPQDISGDFRGMVPLSRALSLSLNIVSVQVLMRTGTDSVIDFASKVTKTNKSRFPTGPALALGVAEL TPYEMALGYSILANKGKDVIPFSVRYVLNQSGTVVYNKEKEVQETLAEEAKNGTIQIIPEATAYIIKQMLIGVAMGGTPT QALRAADKGNYKGESGGKTGSTSSYTNVWYAGFDPKYTSIVWMGFDKSSLSLGKGVTAAGVAAPIWGKMYSRFYNEGPYP SFYPNGKSEEIPADVVKGATCAFNGLSPGPNCPLTGNLFLKPITIAGRTLAVPGGRQCDGDRDHYRSMDLNDFLQRELEI SDDELK
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=730, Percent_Identity=28.0821917808219, Blast_Score=261, Evalue=9e-71, Organism=Escherichia coli, GI1786343, Length=253, Percent_Identity=32.0158102766798, Blast_Score=123, Evalue=4e-29, Organism=Escherichia coli, GI1788867, Length=221, Percent_Identity=33.9366515837104, Blast_Score=122, Evalue=1e-28, Organism=Escherichia coli, GI1789601, Length=148, Percent_Identity=33.7837837837838, Blast_Score=87, Evalue=5e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 3.4.-.-; 2.4.2.-
Molecular weight: Translated: 89483; Mature: 89352
Theoretical pI: Translated: 8.84; Mature: 8.84
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTMNKEKTLRITITTFFSIALFGGLFFGYILSEVNKGKELQKLASYQPTTPTKLYDTNGI CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEECCCCC LVAELYRHKQELLKYSDIPPHVIHAFLSVEDDNFFNHFGIDFLAIVRAAIKNIFAGRIVQ HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC GGSTLTQQLAKTILQQRKKTFGRKFLEALLTLQIEQEYTKEEILEIYFNLIYLGHGTTGL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC SSAANVYFQKDVRDLSIAEAAMLARLPKAPVTYSPFKNPKEAKQAHMVVLGLMAKNGFIP CHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC KDQVQKIHDDFWDRYWPVVITQSPSRSTWGAKLNRAPYFTEWVRQILEKELGEEALYTGG HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCC LRVYTTLDVRKQEISEEELRKGLIEQDKYAFGANFRYAGRADRGLVSLYNLFSSIFPVGV EEEEEEECHHHHHCCHHHHHHHHHHCCCCEECCCCEECCCCCCHHHHHHHHHHHHHCCCC PYVTSLDDRQVFRLHLEKEMAPALELLTDFVPSENESAAVKEFQRSSLVFSSNLHVEGAV CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCEEEECCCEEEEEE ITIDHQTGYIQTMVGGSRFSPKNQFNRAMQARRQTGSAFKPFVYAAAIQNRAVGSGTGIM EEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC DAPLTTITEEGEGYSPQDISGDFRGMVPLSRALSLSLNIVSVQVLMRTGTDSVIDFASKV CCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHEEEEEHHHCCCHHHHHHHHHH TKTNKSRFPTGPALALGVAELTPYEMALGYSILANKGKDVIPFSVRYVLNQSGTVVYNKE HHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEECCH KEVQETLAEEAKNGTIQIIPEATAYIIKQMLIGVAMGGTPTQALRAADKGNYKGESGGKT HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC GSTSSYTNVWYAGFDPKYTSIVWMGFDKSSLSLGKGVTAAGVAAPIWGKMYSRFYNEGPY CCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC PSFYPNGKSEEIPADVVKGATCAFNGLSPGPNCPLTGNLFLKPITIAGRTLAVPGGRQCD CCCCCCCCCCCCCHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCEEECCCCCCCC GDRDHYRSMDLNDFLQRELEISDDELK CCHHHHHCCCHHHHHHHHCCCCCCCCC >Mature Secondary Structure TMNKEKTLRITITTFFSIALFGGLFFGYILSEVNKGKELQKLASYQPTTPTKLYDTNGI CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEECCCCC LVAELYRHKQELLKYSDIPPHVIHAFLSVEDDNFFNHFGIDFLAIVRAAIKNIFAGRIVQ HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC GGSTLTQQLAKTILQQRKKTFGRKFLEALLTLQIEQEYTKEEILEIYFNLIYLGHGTTGL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC SSAANVYFQKDVRDLSIAEAAMLARLPKAPVTYSPFKNPKEAKQAHMVVLGLMAKNGFIP CHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC KDQVQKIHDDFWDRYWPVVITQSPSRSTWGAKLNRAPYFTEWVRQILEKELGEEALYTGG HHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCC LRVYTTLDVRKQEISEEELRKGLIEQDKYAFGANFRYAGRADRGLVSLYNLFSSIFPVGV EEEEEEECHHHHHCCHHHHHHHHHHCCCCEECCCCEECCCCCCHHHHHHHHHHHHHCCCC PYVTSLDDRQVFRLHLEKEMAPALELLTDFVPSENESAAVKEFQRSSLVFSSNLHVEGAV CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCEEEECCCEEEEEE ITIDHQTGYIQTMVGGSRFSPKNQFNRAMQARRQTGSAFKPFVYAAAIQNRAVGSGTGIM EEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC DAPLTTITEEGEGYSPQDISGDFRGMVPLSRALSLSLNIVSVQVLMRTGTDSVIDFASKV CCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHEEEHEEEEEHHHCCCHHHHHHHHHH TKTNKSRFPTGPALALGVAELTPYEMALGYSILANKGKDVIPFSVRYVLNQSGTVVYNKE HHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEECCH KEVQETLAEEAKNGTIQIIPEATAYIIKQMLIGVAMGGTPTQALRAADKGNYKGESGGKT HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC GSTSSYTNVWYAGFDPKYTSIVWMGFDKSSLSLGKGVTAAGVAAPIWGKMYSRFYNEGPY CCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC PSFYPNGKSEEIPADVVKGATCAFNGLSPGPNCPLTGNLFLKPITIAGRTLAVPGGRQCD CCCCCCCCCCCCCHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEEECCCEEECCCCCCCC GDRDHYRSMDLNDFLQRELEISDDELK CCHHHHHCCCHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA