Click here to switch to the map view.

The map label for this gene is tenA [H]

Identifier: 183220371

GI number: 183220371

Start: 1002909

End: 1003604

Strand: Direct

Name: tenA [H]

Synonym: LEPBI_I0967

Alternate gene names: 183220371

Gene position: 1002909-1003604 (Clockwise)

Preceding gene: 183220370

Following gene: 183220372

Centisome position: 27.86

GC content: 46.26

Gene sequence:

>696_bases
ATGCAAAGTCCATTCCCCATTCCAACGTTTGCCCTTGAATGTAAAACATTTGCCAAAGATTCGTTTGGTGCTTCTTTTAC
CCATCCTTTTGTTTTGGCATTGGCAAAAGGAACCCTCGACCCGAAAGTCTTTCGGTTTTACCAAATCCAAGATGCAAAGT
ACTTAGAATCTTTTTCCGATGCTTGCGCCATCCTTTCCACAAAAGTGTCAGACCCTGACGATAAATTATGGCTCATCGAT
GCCGCAAGGATGGCCCTTGTGGTCGAAGGCCAGCTCCACATCGGATATGGAAAAACCTTAGGTTATGATGCAAACACCAT
TGCCAATACAGAGCCCACTCCCAATAACTGGGCCTACCAAAACCACATGGTGGCAACGGTGATGAAAGGGTCTGTCCTCG
AAGGATTCTGTGCCATTGCTCCTTGTCCATGGCTCTACATCGAACTGGGGCAACACCTACTCCAAGAGATGGGGTCCATT
CCACAAGACCATCCTTATGCTTCTTGGTTAAACATGTATTCTGATCCTGGGTTCAACGAATACATGACCCATTTGCTTGC
GAGGGTTCAAAAGTATGCAGACCTTGCGGATGAAACGTCCAAGGCACGTGCCAAAATGGTTTTCCAACAAAGCTGTAATT
ACGAATGGATGTTTTGGGAACAAGCTTGGACAAACCAAAACTGGCCGTCCCGATAA

Upstream 100 bases:

>100_bases
AAAGGATGGAATCCATCCTACAGATGCCGGCCATAAATTGGTAGCGGACACTGTGTACCCTTACATAAAACCACTACTAG
AAAAATAGGAAACATATCTC

Downstream 100 bases:

>100_bases
AGATCCGTTAGCTGGACTTGGGGATGGTTTTGTTTTCCCTTCCATGGTTGCGAACTGATAGATGGGAAATTGAAGAACAC
AAAAAACCAGTTCCTCTCCC

Product: TenA family transcriptional activator

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MQSPFPIPTFALECKTFAKDSFGASFTHPFVLALAKGTLDPKVFRFYQIQDAKYLESFSDACAILSTKVSDPDDKLWLID
AARMALVVEGQLHIGYGKTLGYDANTIANTEPTPNNWAYQNHMVATVMKGSVLEGFCAIAPCPWLYIELGQHLLQEMGSI
PQDHPYASWLNMYSDPGFNEYMTHLLARVQKYADLADETSKARAKMVFQQSCNYEWMFWEQAWTNQNWPSR

Sequences:

>Translated_231_residues
MQSPFPIPTFALECKTFAKDSFGASFTHPFVLALAKGTLDPKVFRFYQIQDAKYLESFSDACAILSTKVSDPDDKLWLID
AARMALVVEGQLHIGYGKTLGYDANTIANTEPTPNNWAYQNHMVATVMKGSVLEGFCAIAPCPWLYIELGQHLLQEMGSI
PQDHPYASWLNMYSDPGFNEYMTHLLARVQKYADLADETSKARAKMVFQQSCNYEWMFWEQAWTNQNWPSR
>Mature_231_residues
MQSPFPIPTFALECKTFAKDSFGASFTHPFVLALAKGTLDPKVFRFYQIQDAKYLESFSDACAILSTKVSDPDDKLWLID
AARMALVVEGQLHIGYGKTLGYDANTIANTEPTPNNWAYQNHMVATVMKGSVLEGFCAIAPCPWLYIELGQHLLQEMGSI
PQDHPYASWLNMYSDPGFNEYMTHLLARVQKYADLADETSKARAKMVFQQSCNYEWMFWEQAWTNQNWPSR

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 26277; Mature: 26277

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSPFPIPTFALECKTFAKDSFGASFTHPFVLALAKGTLDPKVFRFYQIQDAKYLESFSD
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHEEEEEECCHHHHHHHHH
ACAILSTKVSDPDDKLWLIDAARMALVVEGQLHIGYGKTLGYDANTIANTEPTPNNWAYQ
HHHHHHCCCCCCCCCEEEEEECEEEEEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
NHMVATVMKGSVLEGFCAIAPCPWLYIELGQHLLQEMGSIPQDHPYASWLNMYSDPGFNE
CHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHH
YMTHLLARVQKYADLADETSKARAKMVFQQSCNYEWMFWEQAWTNQNWPSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCC
>Mature Secondary Structure
MQSPFPIPTFALECKTFAKDSFGASFTHPFVLALAKGTLDPKVFRFYQIQDAKYLESFSD
CCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHEEEEEECCHHHHHHHHH
ACAILSTKVSDPDDKLWLIDAARMALVVEGQLHIGYGKTLGYDANTIANTEPTPNNWAYQ
HHHHHHCCCCCCCCCEEEEEECEEEEEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
NHMVATVMKGSVLEGFCAIAPCPWLYIELGQHLLQEMGSIPQDHPYASWLNMYSDPGFNE
CHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHH
YMTHLLARVQKYADLADETSKARAKMVFQQSCNYEWMFWEQAWTNQNWPSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]