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The map label for this gene is cheW1 [H]

Identifier: 183220325

GI number: 183220325

Start: 953150

End: 953653

Strand: Reverse

Name: cheW1 [H]

Synonym: LEPBI_I0921

Alternate gene names: 183220325

Gene position: 953653-953150 (Counterclockwise)

Preceding gene: 183220326

Following gene: 183220324

Centisome position: 26.49

GC content: 38.29

Gene sequence:

>504_bases
ATGAACATACCATCCAAGTCATGGGAAACAGTTGAAGATGAAGATACAATGAAGGATTTGTATCTTTGTTTTAGTCTAGA
AGGACGATTCTATGCATTCGAAGTGAGGTATTTAACAGAAATTTTAGCCTTACCTGCCATTACGACGATTCCTGGGACTG
CCGATTTTTTAAAAGGTGTGATCAATATACGAGGAAAAATCATTCCTGTAATGGATGTTAGACTCAGATTTGATATGCCA
TTCCAACCCTACCACGAAAGGACATGTGTCTTACTCGTTGAATTGGAAGGTCACCCATTAGGGCTCATCGTAGATAAGGT
GAATGATGTGGTAAAAATCCCACAAGAAAACATTGACATCGCTCCCAAAATTGGAGAATCAAAATCTTCTCGGTTTATTT
ATGCCACAGGACGAGTCGGTGATAGTGTCAAAATTTTAATTAACTTACAACGATTGCTCACCCAAGAAGAAAGTTATATG
ATCCAAGACATCCCTGGAAATTGA

Upstream 100 bases:

>100_bases
GCGGTCCGTGATTATGGGTTTCAAATTAAAAGAGGACGGATCGAAAACAACAGCATTGACTCGAATCGAAAAACCTCGAA
TTGTATTATAGGGCATCACC

Downstream 100 bases:

>100_bases
GACATGGAAAGAGAAGATGTTTTAGAATACCTAACAGAAGCAAAGGAATGTTTAGAAAACATTGAAACTGGTTTGCTTAA
CTTCGAAAAAACAACGTTAG

Product: signal transducer CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNIPSKSWETVEDEDTMKDLYLCFSLEGRFYAFEVRYLTEILALPAITTIPGTADFLKGVINIRGKIIPVMDVRLRFDMP
FQPYHERTCVLLVELEGHPLGLIVDKVNDVVKIPQENIDIAPKIGESKSSRFIYATGRVGDSVKILINLQRLLTQEESYM
IQDIPGN

Sequences:

>Translated_167_residues
MNIPSKSWETVEDEDTMKDLYLCFSLEGRFYAFEVRYLTEILALPAITTIPGTADFLKGVINIRGKIIPVMDVRLRFDMP
FQPYHERTCVLLVELEGHPLGLIVDKVNDVVKIPQENIDIAPKIGESKSSRFIYATGRVGDSVKILINLQRLLTQEESYM
IQDIPGN
>Mature_167_residues
MNIPSKSWETVEDEDTMKDLYLCFSLEGRFYAFEVRYLTEILALPAITTIPGTADFLKGVINIRGKIIPVMDVRLRFDMP
FQPYHERTCVLLVELEGHPLGLIVDKVNDVVKIPQENIDIAPKIGESKSSRFIYATGRVGDSVKILINLQRLLTQEESYM
IQDIPGN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=141, Percent_Identity=32.6241134751773, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 19003; Mature: 19003

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPSKSWETVEDEDTMKDLYLCFSLEGRFYAFEVRYLTEILALPAITTIPGTADFLKGV
CCCCCCCCCCCCCCHHHHEEEEEEEECCCEEEEEHHHHHHHHHHCCEECCCCCHHHHHHH
INIRGKIIPVMDVRLRFDMPFQPYHERTCVLLVELEGHPLGLIVDKVNDVVKIPQENIDI
HHCCCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCCHHEECCCCCCCC
APKIGESKSSRFIYATGRVGDSVKILINLQRLLTQEESYMIQDIPGN
CCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure
MNIPSKSWETVEDEDTMKDLYLCFSLEGRFYAFEVRYLTEILALPAITTIPGTADFLKGV
CCCCCCCCCCCCCCHHHHEEEEEEEECCCEEEEEHHHHHHHHHHCCEECCCCCHHHHHHH
INIRGKIIPVMDVRLRFDMPFQPYHERTCVLLVELEGHPLGLIVDKVNDVVKIPQENIDI
HHCCCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEEECCCHHEECCCCCCCC
APKIGESKSSRFIYATGRVGDSVKILINLQRLLTQEESYMIQDIPGN
CCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]