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The map label for this gene is glyQS [H]

Identifier: 183220295

GI number: 183220295

Start: 910462

End: 911946

Strand: Reverse

Name: glyQS [H]

Synonym: LEPBI_I0890

Alternate gene names: 183220295

Gene position: 911946-910462 (Counterclockwise)

Preceding gene: 183220298

Following gene: 183220294

Centisome position: 25.33

GC content: 42.63

Gene sequence:

>1485_bases
TTGAGAGTTTGCCGAATCCATTCTTTAGTCTTATCTCAAGGAAAATACTTTGAATTTTCATGGAAAACAAAAAATTTGGC
GGATATGGCACAGCCGAAAGAGAAAGAAGAACAGTCGCTCAAACCCATAGTCGCAGTCTCCAAACGAAGAGGCTTTGTTT
TCCCAGGATCCGAAATTTACGGAGGCCTCTCCAATACATTTGACTATGGTCCGAACGGAATTGAAGTTTTGAACAATTTA
AAACGACTTTGGTGGGAATACTTTGTCCACCGTAGGGATGATGTTTTGGGACTTGATTCTTCCATTCTCCTCCACCCACG
TGTTTGGGAAGCATCTGGCCACATTTCCAACTTCAACGATCCACTTATGGATTGTAAAAAATGCAAAACACGAGTGCGCG
TGGATAAGTTTTTAGAAGATAAGGAAGGGGAAGGAGCAGCAACAGGGAAAACTTTGGAAGAACTCACAAATACCATCCGT
GACAAAGCCTATGCTTGCCCCACTTGCGGAACAGTGGGAAGTTTTACGGATGCACGCCAGTTCAATTTGATGTTCAAAAC
ATCACATGGTGCCTCCGAAGAAGGAGCCACTGACATTTACCTTCGTCCGGAAACTGCCCAAGGGATCTTCATCAATTTTA
AAAACGTAACCCAAATTGCGCGGAAAAAAGTACCATTCGGAATTGCACAGATTGGAAAGTCATTTCGGAACGAAATCATG
GCACGCCAGTTTATCTTTCGAACCCGTGAGTTCGAACAAATGGAGATGGAATTTTTCTGTGAACCAGGCACTCAAAAAGA
ATGGTTTAAGTATTGGGTGGACTACTGCATGGATTGGCTTGTGAATGTGGTGGGTTTAAAAAAAGAAAACCTACGAGTGC
GTGAACACGAAAAAGAAGAACTTTCGTTTTATAGTGATTCCACAAGTGACATCGAATACAAATACCCGTTTGGTTGGGGT
GAACTTTGGGGTGTTGCTTCAAGGACTGATTATGACCTCACCCAACACGAAACATTTTCTTCGGAAGATTTGAAGTACCA
TGACCTAGACCAAAAGAAAAAGTACCTGCCCTATGTTGTTGAACCTGCTCTTGGTCTTAATAGACTTTTCCTTGCAGTGT
TATGTGACGCTTACGAAGAAGAAAAATTAGAAAAAGACGACATTCGTACTGTCCTTCGGTTTGGCAAACGTGTGAGTCCC
ATGAAAGTCGCCATTTTTCCTCTCATGAAAAAAGACGGGCTCGATGCCAAAGCCAAAGAAATTTATACCGACCTTCGTAA
CCATTGGTATGTAGATTATGATGATAGTGGTGCCATTGGAAAACGGTACCGTCGTCATGACGAAATTGGAACGCCTTTCT
GTATCACAGTCGATTACGACACGATGAGTGACGGAACAGTCACTATCCGAGAAAGGGATTCGATGAAACAAGAAAGGATT
GCTGTGGCCGATCTCAAATCGTATCTCATCCAAAGAATGGTTTAG

Upstream 100 bases:

>100_bases
ACGCAAAGAGGATTCCAAATGCGAAAAAAGGCCCCAAACTGAAAAGGGGTGAGAGCCAAAGGAAAAACGTTAAGGATTTT
TTTGCCCAGGGAGAGAGGTA

Downstream 100 bases:

>100_bases
TTGGTCCGCGATCTACTAGAATCTGACAGAAACCAAACCATCGAACTCGTGAATCAGTTTTTCCGAAAGGTAAACGAACT
TGAGTTAGATGGTTTGTTTC

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MRVCRIHSLVLSQGKYFEFSWKTKNLADMAQPKEKEEQSLKPIVAVSKRRGFVFPGSEIYGGLSNTFDYGPNGIEVLNNL
KRLWWEYFVHRRDDVLGLDSSILLHPRVWEASGHISNFNDPLMDCKKCKTRVRVDKFLEDKEGEGAATGKTLEELTNTIR
DKAYACPTCGTVGSFTDARQFNLMFKTSHGASEEGATDIYLRPETAQGIFINFKNVTQIARKKVPFGIAQIGKSFRNEIM
ARQFIFRTREFEQMEMEFFCEPGTQKEWFKYWVDYCMDWLVNVVGLKKENLRVREHEKEELSFYSDSTSDIEYKYPFGWG
ELWGVASRTDYDLTQHETFSSEDLKYHDLDQKKKYLPYVVEPALGLNRLFLAVLCDAYEEEKLEKDDIRTVLRFGKRVSP
MKVAIFPLMKKDGLDAKAKEIYTDLRNHWYVDYDDSGAIGKRYRRHDEIGTPFCITVDYDTMSDGTVTIRERDSMKQERI
AVADLKSYLIQRMV

Sequences:

>Translated_494_residues
MRVCRIHSLVLSQGKYFEFSWKTKNLADMAQPKEKEEQSLKPIVAVSKRRGFVFPGSEIYGGLSNTFDYGPNGIEVLNNL
KRLWWEYFVHRRDDVLGLDSSILLHPRVWEASGHISNFNDPLMDCKKCKTRVRVDKFLEDKEGEGAATGKTLEELTNTIR
DKAYACPTCGTVGSFTDARQFNLMFKTSHGASEEGATDIYLRPETAQGIFINFKNVTQIARKKVPFGIAQIGKSFRNEIM
ARQFIFRTREFEQMEMEFFCEPGTQKEWFKYWVDYCMDWLVNVVGLKKENLRVREHEKEELSFYSDSTSDIEYKYPFGWG
ELWGVASRTDYDLTQHETFSSEDLKYHDLDQKKKYLPYVVEPALGLNRLFLAVLCDAYEEEKLEKDDIRTVLRFGKRVSP
MKVAIFPLMKKDGLDAKAKEIYTDLRNHWYVDYDDSGAIGKRYRRHDEIGTPFCITVDYDTMSDGTVTIRERDSMKQERI
AVADLKSYLIQRMV
>Mature_494_residues
MRVCRIHSLVLSQGKYFEFSWKTKNLADMAQPKEKEEQSLKPIVAVSKRRGFVFPGSEIYGGLSNTFDYGPNGIEVLNNL
KRLWWEYFVHRRDDVLGLDSSILLHPRVWEASGHISNFNDPLMDCKKCKTRVRVDKFLEDKEGEGAATGKTLEELTNTIR
DKAYACPTCGTVGSFTDARQFNLMFKTSHGASEEGATDIYLRPETAQGIFINFKNVTQIARKKVPFGIAQIGKSFRNEIM
ARQFIFRTREFEQMEMEFFCEPGTQKEWFKYWVDYCMDWLVNVVGLKKENLRVREHEKEELSFYSDSTSDIEYKYPFGWG
ELWGVASRTDYDLTQHETFSSEDLKYHDLDQKKKYLPYVVEPALGLNRLFLAVLCDAYEEEKLEKDDIRTVLRFGKRVSP
MKVAIFPLMKKDGLDAKAKEIYTDLRNHWYVDYDDSGAIGKRYRRHDEIGTPFCITVDYDTMSDGTVTIRERDSMKQERI
AVADLKSYLIQRMV

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=350, Percent_Identity=30, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI70887790, Length=313, Percent_Identity=23.3226837060703, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32564541, Length=366, Percent_Identity=30.327868852459, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17554996, Length=366, Percent_Identity=30.327868852459, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6325338, Length=379, Percent_Identity=31.9261213720317, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6319597, Length=397, Percent_Identity=28.7153652392947, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357965, Length=350, Percent_Identity=32.2857142857143, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24664462, Length=350, Percent_Identity=32.2857142857143, Blast_Score=161, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 57558; Mature: 57558

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVCRIHSLVLSQGKYFEFSWKTKNLADMAQPKEKEEQSLKPIVAVSKRRGFVFPGSEIY
CCEEHHHHHHHCCCCEEEEEECCCCHHHHCCCCHHHHHHCCHHHHHHCCCCEECCCHHHH
GGLSNTFDYGPNGIEVLNNLKRLWWEYFVHRRDDVLGLDSSILLHPRVWEASGHISNFND
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEEECCCCCCCCCCC
PLMDCKKCKTRVRVDKFLEDKEGEGAATGKTLEELTNTIRDKAYACPTCGTVGSFTDARQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
FNLMFKTSHGASEEGATDIYLRPETAQGIFINFKNVTQIARKKVPFGIAQIGKSFRNEIM
EEEEEEECCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARQFIFRTREFEQMEMEFFCEPGTQKEWFKYWVDYCMDWLVNVVGLKKENLRVREHEKEE
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHH
LSFYSDSTSDIEYKYPFGWGELWGVASRTDYDLTQHETFSSEDLKYHDLDQKKKYLPYVV
HHEECCCCCCEEEECCCCHHHHHCCCCCCCCCCHHCCCCCCCCCEECCCCCHHCCCCEEE
EPALGLNRLFLAVLCDAYEEEKLEKDDIRTVLRFGKRVSPMKVAIFPLMKKDGLDAKAKE
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHH
IYTDLRNHWYVDYDDSGAIGKRYRRHDEIGTPFCITVDYDTMSDGTVTIRERDSMKQERI
HHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHH
AVADLKSYLIQRMV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRVCRIHSLVLSQGKYFEFSWKTKNLADMAQPKEKEEQSLKPIVAVSKRRGFVFPGSEIY
CCEEHHHHHHHCCCCEEEEEECCCCHHHHCCCCHHHHHHCCHHHHHHCCCCEECCCHHHH
GGLSNTFDYGPNGIEVLNNLKRLWWEYFVHRRDDVLGLDSSILLHPRVWEASGHISNFND
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEEECCCCCCCCCCC
PLMDCKKCKTRVRVDKFLEDKEGEGAATGKTLEELTNTIRDKAYACPTCGTVGSFTDARQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
FNLMFKTSHGASEEGATDIYLRPETAQGIFINFKNVTQIARKKVPFGIAQIGKSFRNEIM
EEEEEEECCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARQFIFRTREFEQMEMEFFCEPGTQKEWFKYWVDYCMDWLVNVVGLKKENLRVREHEKEE
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHH
LSFYSDSTSDIEYKYPFGWGELWGVASRTDYDLTQHETFSSEDLKYHDLDQKKKYLPYVV
HHEECCCCCCEEEECCCCHHHHHCCCCCCCCCCHHCCCCCCCCCEECCCCCHHCCCCEEE
EPALGLNRLFLAVLCDAYEEEKLEKDDIRTVLRFGKRVSPMKVAIFPLMKKDGLDAKAKE
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCHHHHH
IYTDLRNHWYVDYDDSGAIGKRYRRHDEIGTPFCITVDYDTMSDGTVTIRERDSMKQERI
HHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHH
AVADLKSYLIQRMV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA