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The map label for this gene is 183220283

Identifier: 183220283

GI number: 183220283

Start: 896365

End: 897357

Strand: Reverse

Name: 183220283

Synonym: LEPBI_I0878

Alternate gene names: NA

Gene position: 897357-896365 (Counterclockwise)

Preceding gene: 183220284

Following gene: 183220273

Centisome position: 24.93

GC content: 39.38

Gene sequence:

>993_bases
TTGGATTTTCATATTGGCAATAAAACTCTTACCAGAAACTCAGAACCATATTTAGTAGCAGAGATTGGACTGAACCATAA
CGCCGACTTAGAAATTGGCAAACGTACGATTGAGAAAGCAAAGGAATCCGGTGCCCATGCGGTAAAGTTCCAAACCTACC
GCACAGAAGAATTCATTGATACGAAAAACCCTGAAGTAAAGTTTTTATTTGATATCTTCAAACAATACGAATTGGATGAA
AAATTCCATAGAGAATTTCAAAAAACAGCCCTAAATTTGGGGCTCGATTTTTTTTCCACTCCGCTTTGTGATTCTGCAGT
TGATTTGTTATCTAACTTAAATGTCCCAATTTTTAAAATTGCTTCTGGAGACATCGTCAACTTACCACTGCTCAACAAAG
TGATCCAAACAAAAAAACCCATCATTGTGTCCACGGGGGCAGCTCTGCCAGAAGAAGTGATCCGTGCCATTTCTAAATTC
CAAAAAGAGAATGCAGAAGTATGTTTGTTACATTGTGTATCAATGTACCCAACTCCATTGGATAAAGTAAACCTTCAATC
CATCCCCTATTATTTGGACACAACAGATTATGTCATTGGTTTCAGTGACCATTCGGATGGAACACTCGCCTCTTCCCTTG
CTATTGGACTTGGGGCTGTTGTCATTGAAAAACATTTTACTTTGGATCGAAATTTGGAAGGCCCAGACCATAGCATTTCT
ATGGACCCAGTATCTTTTAAAAAATTAGCTGAAGATACTAAACATAGTTATGTGATGGGTGGGAAGTATGGAAAAAACAC
TCACAAAGAAGAAACCAGTGGTTGGTTTTACGGACGAAGGTCTTTGTACAAACAAAACCAATCGGTCATGAGCCTACGAC
CTGCCCTACATACAAAAGACAATACGGTTTTAGATTCTTGGGAATTGGACTTGGTGGGGGATCCTTCATTATTACCAGAA
GGACCCATCCGAGTGGCACCTATCAGAAAATAG

Upstream 100 bases:

>100_bases
CATGACAACACTTGCGATCTTTACCTCCTTTCTGGTATTCCAATTGGGAAAAATTTTAGGATTTGTTTAATCTGCCGACA
ATGAAGTCTAGAGGCTCACT

Downstream 100 bases:

>100_bases
GTGCTTGAAAGTCCGAAAGTTTTACATCTTTTGGATGATTTGTTCGAGTAAAGTTTTTAAGAACACAGGATTTGGTGTTC
CACTTTCAATTCGACGATCA

Product: putative N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDFHIGNKTLTRNSEPYLVAEIGLNHNADLEIGKRTIEKAKESGAHAVKFQTYRTEEFIDTKNPEVKFLFDIFKQYELDE
KFHREFQKTALNLGLDFFSTPLCDSAVDLLSNLNVPIFKIASGDIVNLPLLNKVIQTKKPIIVSTGAALPEEVIRAISKF
QKENAEVCLLHCVSMYPTPLDKVNLQSIPYYLDTTDYVIGFSDHSDGTLASSLAIGLGAVVIEKHFTLDRNLEGPDHSIS
MDPVSFKKLAEDTKHSYVMGGKYGKNTHKEETSGWFYGRRSLYKQNQSVMSLRPALHTKDNTVLDSWELDLVGDPSLLPE
GPIRVAPIRK

Sequences:

>Translated_330_residues
MDFHIGNKTLTRNSEPYLVAEIGLNHNADLEIGKRTIEKAKESGAHAVKFQTYRTEEFIDTKNPEVKFLFDIFKQYELDE
KFHREFQKTALNLGLDFFSTPLCDSAVDLLSNLNVPIFKIASGDIVNLPLLNKVIQTKKPIIVSTGAALPEEVIRAISKF
QKENAEVCLLHCVSMYPTPLDKVNLQSIPYYLDTTDYVIGFSDHSDGTLASSLAIGLGAVVIEKHFTLDRNLEGPDHSIS
MDPVSFKKLAEDTKHSYVMGGKYGKNTHKEETSGWFYGRRSLYKQNQSVMSLRPALHTKDNTVLDSWELDLVGDPSLLPE
GPIRVAPIRK
>Mature_330_residues
MDFHIGNKTLTRNSEPYLVAEIGLNHNADLEIGKRTIEKAKESGAHAVKFQTYRTEEFIDTKNPEVKFLFDIFKQYELDE
KFHREFQKTALNLGLDFFSTPLCDSAVDLLSNLNVPIFKIASGDIVNLPLLNKVIQTKKPIIVSTGAALPEEVIRAISKF
QKENAEVCLLHCVSMYPTPLDKVNLQSIPYYLDTTDYVIGFSDHSDGTLASSLAIGLGAVVIEKHFTLDRNLEGPDHSIS
MDPVSFKKLAEDTKHSYVMGGKYGKNTHKEETSGWFYGRRSLYKQNQSVMSLRPALHTKDNTVLDSWELDLVGDPSLLPE
GPIRVAPIRK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=248, Percent_Identity=34.2741935483871, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21357081, Length=245, Percent_Identity=34.6938775510204, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37075; Mature: 37075

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFHIGNKTLTRNSEPYLVAEIGLNHNADLEIGKRTIEKAKESGAHAVKFQTYRTEEFID
CCEECCCCEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHC
TKNPEVKFLFDIFKQYELDEKFHREFQKTALNLGLDFFSTPLCDSAVDLLSNLNVPIFKI
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCCCEEEE
ASGDIVNLPLLNKVIQTKKPIIVSTGAALPEEVIRAISKFQKENAEVCLLHCVSMYPTPL
CCCCEEECHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCC
DKVNLQSIPYYLDTTDYVIGFSDHSDGTLASSLAIGLGAVVIEKHFTLDRNLEGPDHSIS
CCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
MDPVSFKKLAEDTKHSYVMGGKYGKNTHKEETSGWFYGRRSLYKQNQSVMSLRPALHTKD
CCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCC
NTVLDSWELDLVGDPSLLPEGPIRVAPIRK
CCEEECEEEEECCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MDFHIGNKTLTRNSEPYLVAEIGLNHNADLEIGKRTIEKAKESGAHAVKFQTYRTEEFID
CCEECCCCEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHC
TKNPEVKFLFDIFKQYELDEKFHREFQKTALNLGLDFFSTPLCDSAVDLLSNLNVPIFKI
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCCCEEEE
ASGDIVNLPLLNKVIQTKKPIIVSTGAALPEEVIRAISKFQKENAEVCLLHCVSMYPTPL
CCCCEEECHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHCCCCC
DKVNLQSIPYYLDTTDYVIGFSDHSDGTLASSLAIGLGAVVIEKHFTLDRNLEGPDHSIS
CCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
MDPVSFKKLAEDTKHSYVMGGKYGKNTHKEETSGWFYGRRSLYKQNQSVMSLRPALHTKD
CCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCC
NTVLDSWELDLVGDPSLLPEGPIRVAPIRK
CCEEECEEEEECCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]