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The map label for this gene is slt [C]

Identifier: 183220269

GI number: 183220269

Start: 882033

End: 882752

Strand: Direct

Name: slt [C]

Synonym: LEPBI_I0862

Alternate gene names: 183220269

Gene position: 882033-882752 (Clockwise)

Preceding gene: 183220264

Following gene: 183220270

Centisome position: 24.5

GC content: 42.92

Gene sequence:

>720_bases
GTGTCGGAAACTGGCCTTATTGTGCAATGCACAATAAGGAGACGGTCAGTCACCATGCGAAAACAAAAGAAATTCACTCA
AAAATTAGCATCCATAGGGCTCATTTTGCTCTTCCTCCTCGAGTCTTATGGGAAAATCAATCCCGCAGGGAATGCCCCCG
CCAATGATGCGGCAAAACTCAAGTTACATTCCCTAATCTCCAAAACCCGACCTGGTCTTTCAAAAAAAGAACAGAAAGAT
TTGGTTCTTGTCGTGGAAAGAGCATCCTACCACATCCGATTCCCCAAAAAAACGAAAACTACCAATACAGCTCCCGTTGA
TAAATTGGGTTTTCTCGTTGGTCTCATCCAAACGGAATCACAGTTCCACACTCGTGCTAAATCGCATAAAGGAGCACTTG
GGCTCATGCAAGTCATGCCTGAAACGGCAAGGTGGCTCGCCAAAAAAGAAGGGATTCCCTTTTCTTCCGCTAAAGAACTG
TATGAACCTGAAACGAATCTACTCATTGGTGTTCTTTATTTGAATTATTTGATGGAGCGCACAGAGACACTCGAAGCAAC
ATTGTTAGCTTATAATGCCGGTCTCGGTGGTTATAAACGATTTGGTGGTGTCCCTTCTTATTCAAGAACAGTATACAAAT
ACTACGAAGAATGGAAACAAATGCCAGTTCCATCCGAAATCCCAATTTCTGAATCCTTAGCGAGTCTCTTTTCCATTTAA

Upstream 100 bases:

>100_bases
TCTCCAGAAATGGACAAAATGAAACTTTCGGCAAGCATTTCCCGATTGTCCTATTTTTTCTTTGTGCGTCGCACAAATAA
CTCCTTGTCCTCCGAGGGTC

Downstream 100 bases:

>100_bases
ATTTTACTTTACATCGTTTCAAAACCGACAAGGCTCTTATTCGTTTTACTAAAGAAAAGGAAGGGAGCGTATGGATTTAT
TTCGTAGATACGGATTGTAT

Product: putative transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Soluble Lytic Murein Transglycosylase; Transglycosylase; Lytic Murein Transglycosylase; Transglycosylase SLT Domain Protein; Transglycosylase SLT Domain-Containing Protein; Transglycosylase Slt Domain Protein; Murein Transglycosylase Domain-Containing Protein; Lytic Transglycosylase; Secreted Protein

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSETGLIVQCTIRRRSVTMRKQKKFTQKLASIGLILLFLLESYGKINPAGNAPANDAAKLKLHSLISKTRPGLSKKEQKD
LVLVVERASYHIRFPKKTKTTNTAPVDKLGFLVGLIQTESQFHTRAKSHKGALGLMQVMPETARWLAKKEGIPFSSAKEL
YEPETNLLIGVLYLNYLMERTETLEATLLAYNAGLGGYKRFGGVPSYSRTVYKYYEEWKQMPVPSEIPISESLASLFSI

Sequences:

>Translated_239_residues
MSETGLIVQCTIRRRSVTMRKQKKFTQKLASIGLILLFLLESYGKINPAGNAPANDAAKLKLHSLISKTRPGLSKKEQKD
LVLVVERASYHIRFPKKTKTTNTAPVDKLGFLVGLIQTESQFHTRAKSHKGALGLMQVMPETARWLAKKEGIPFSSAKEL
YEPETNLLIGVLYLNYLMERTETLEATLLAYNAGLGGYKRFGGVPSYSRTVYKYYEEWKQMPVPSEIPISESLASLFSI
>Mature_238_residues
SETGLIVQCTIRRRSVTMRKQKKFTQKLASIGLILLFLLESYGKINPAGNAPANDAAKLKLHSLISKTRPGLSKKEQKDL
VLVVERASYHIRFPKKTKTTNTAPVDKLGFLVGLIQTESQFHTRAKSHKGALGLMQVMPETARWLAKKEGIPFSSAKELY
EPETNLLIGVLYLNYLMERTETLEATLLAYNAGLGGYKRFGGVPSYSRTVYKYYEEWKQMPVPSEIPISESLASLFSI

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 26817; Mature: 26686

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETGLIVQCTIRRRSVTMRKQKKFTQKLASIGLILLFLLESYGKINPAGNAPANDAAKL
CCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
KLHSLISKTRPGLSKKEQKDLVLVVERASYHIRFPKKTKTTNTAPVDKLGFLVGLIQTES
HHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
QFHTRAKSHKGALGLMQVMPETARWLAKKEGIPFSSAKELYEPETNLLIGVLYLNYLMER
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
TETLEATLLAYNAGLGGYKRFGGVPSYSRTVYKYYEEWKQMPVPSEIPISESLASLFSI
HHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SETGLIVQCTIRRRSVTMRKQKKFTQKLASIGLILLFLLESYGKINPAGNAPANDAAKL
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
KLHSLISKTRPGLSKKEQKDLVLVVERASYHIRFPKKTKTTNTAPVDKLGFLVGLIQTES
HHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
QFHTRAKSHKGALGLMQVMPETARWLAKKEGIPFSSAKELYEPETNLLIGVLYLNYLMER
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
TETLEATLLAYNAGLGGYKRFGGVPSYSRTVYKYYEEWKQMPVPSEIPISESLASLFSI
HHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA