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The map label for this gene is crp [C]

Identifier: 183220232

GI number: 183220232

Start: 838482

End: 839003

Strand: Reverse

Name: crp [C]

Synonym: LEPBI_I0825

Alternate gene names: 183220232

Gene position: 839003-838482 (Counterclockwise)

Preceding gene: 183220240

Following gene: 183220231

Centisome position: 23.31

GC content: 40.04

Gene sequence:

>522_bases
ATGCAACTTCCCCTTTGGAAATCCATTCTCAAACGCGATGACAATCCCATTACAGAGATTTCACATTTTTTACGTGAAAC
GGCCATCTTTGAAGGTATGTCACGAAGGACACTTCGTGAAGTGGCAAGACTCATTCATAAACGTAAATACTATGCGGGTG
AAACTATATTCTACCAAGGGCAAGCGGGTACGGGGGTTTATTTAATCCTACAAGGAAAAGTAGAAATCTTTTCCGAAAGA
GAAGGTGTTACCTTAAAACTCGCCGAACTGGAAAAAGGCGCATTTTTTGGGGAGCTGGCTCTTTTCCAAGATTTTCCAAG
ATCTGCAACTGCAGTCACACTTGTGGATTCTATCTTACTTGGTTTTTTCCAACCAGAACTCAAAACATTATTAGAAACAA
AACCAAGAGTTGGAAATGATTTGCTCCTCAGTTTTGCCTCTATCATCGCAGATAGACTTCGCAAAACAAACGATACATTA
GAAGCGGCTTACTTTAAGAGCAAAAAGAATAAGGCAAGATGA

Upstream 100 bases:

>100_bases
GACATCGGTTCCTGTCCCCGTTACATAAAAAGCTTGGCCCATAAGAGCAAGTTTTATCAATTCCAGACCTCGTCCATCCG
ATTTATATAGTAGAGGCAAT

Downstream 100 bases:

>100_bases
ACTTCAAAGAAAATTCGATCTCATCCTTAGTGTTACGGTCTGCTTTTTTTGGCCTCATTGCATTGACAATTCTCATCGGC
ATTGTAGGTGTTAAGTTTTT

Product: putative cAMP-dependent protein kinase

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Catabolite Gene Activator; Histidine Kinase; Stage II Sporulation E Family Protein; Esterase Of Alpha-Beta Hydrolase Superfamily; Transcriptional Regulatory Protein; Mechanosensitive Ion Channel Protein MscS; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MQLPLWKSILKRDDNPITEISHFLRETAIFEGMSRRTLREVARLIHKRKYYAGETIFYQGQAGTGVYLILQGKVEIFSER
EGVTLKLAELEKGAFFGELALFQDFPRSATAVTLVDSILLGFFQPELKTLLETKPRVGNDLLLSFASIIADRLRKTNDTL
EAAYFKSKKNKAR

Sequences:

>Translated_173_residues
MQLPLWKSILKRDDNPITEISHFLRETAIFEGMSRRTLREVARLIHKRKYYAGETIFYQGQAGTGVYLILQGKVEIFSER
EGVTLKLAELEKGAFFGELALFQDFPRSATAVTLVDSILLGFFQPELKTLLETKPRVGNDLLLSFASIIADRLRKTNDTL
EAAYFKSKKNKAR
>Mature_173_residues
MQLPLWKSILKRDDNPITEISHFLRETAIFEGMSRRTLREVARLIHKRKYYAGETIFYQGQAGTGVYLILQGKVEIFSER
EGVTLKLAELEKGAFFGELALFQDFPRSATAVTLVDSILLGFFQPELKTLLETKPRVGNDLLLSFASIIADRLRKTNDTL
EAAYFKSKKNKAR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 19746; Mature: 19746

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPLWKSILKRDDNPITEISHFLRETAIFEGMSRRTLREVARLIHKRKYYAGETIFYQG
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
QAGTGVYLILQGKVEIFSEREGVTLKLAELEKGAFFGELALFQDFPRSATAVTLVDSILL
CCCCCEEEEEECCEEEECCCCCCEEEEEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
GFFQPELKTLLETKPRVGNDLLLSFASIIADRLRKTNDTLEAAYFKSKKNKAR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLPLWKSILKRDDNPITEISHFLRETAIFEGMSRRTLREVARLIHKRKYYAGETIFYQG
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
QAGTGVYLILQGKVEIFSEREGVTLKLAELEKGAFFGELALFQDFPRSATAVTLVDSILL
CCCCCEEEEEECCEEEECCCCCCEEEEEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
GFFQPELKTLLETKPRVGNDLLLSFASIIADRLRKTNDTLEAAYFKSKKNKAR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA