Click here to switch to the map view.

The map label for this gene is atpD

Identifier: 183220215

GI number: 183220215

Start: 821331

End: 822737

Strand: Direct

Name: atpD

Synonym: LEPBI_I0807

Alternate gene names: 183220215

Gene position: 821331-822737 (Clockwise)

Preceding gene: 183220214

Following gene: 183220216

Centisome position: 22.82

GC content: 42.93

Gene sequence:

>1407_bases
ATGAATAAAGGTAAAATTAAACAAATCATCGGTTCAGTAATGGACATCAGTTTTGAATCCGGGAATATGCCTGAGATCTA
CAATGCCGTAGAGATTCAAACAAAAGTAAACGGCAAAGACGTAACAATTACTGCAGAAGTGCAACAACACATTGGAGACA
ACACAGTTCGTGCCATCTCCCTTCAATCCACAGACGGATTAAAAAGAGGTTTAGAAGTGACTGATACAGGAATTCCAATT
TCTGTTCCAGTCGGAACAAAAACTCTTGGTCGTATCTTTAACGTTCTTGGTGAAGCAATCGATGAACTCGGTGATCTTCC
AAAAGACGTTAAAAAAATGCCAATCCATAGAAATGCACCTACTTACGAAGAAATTAAACCAAAAACTGAAATCTTTGAAA
CAGGGATTAAGGTCATCGACCTTCTTGCTCCTTACATCAAAGGGGGTAAAACTGGTCTTTTTGGTGGTGCTGGGGTTGGT
AAAACTGTATTAATTCAAGAGCTTATCAATAACATCGCAAAACAACATGGTGGTTTCTCTGTGTTCGCTGGTGTGGGTGA
AAGGACTCGTGAAGGAAACGACCTTTGGAATGAAATGAAAGAATCGGGAGTTATCGACAAAACCGTTCTTTGTTTTGGTC
AGATGAACGAACCACCAGGTGCTCGTCTTCGTGTGGCTCTTTCTGCTTTGACAATGGCGGAAAACTTCCGTGATGAATCA
GGATCCGATATCCTTTTATTCGTAGATAATATCTTCCGTTTTTCACAAGCAGGTTCTGAAGTGTCAGCCCTTCTTGGTCG
TATGCCATCTGCGGTAGGTTACCAACCAACTCTTTCCACAGAGATGGGGGGACTACAAGAACGAATCACTTCCACAACAC
GAGGTTCCATTACTTCCGTGCAAGCGATCTACGTTCCTGCCGACGACTTAACTGACCCGGCTCCTGCAACTGCTTTCACT
CACTTGGATGCAACAACAGTTCTTTCACGAGCGATTTCTGAAAAAGGGATTTATCCTGCAGTGGATCCTCTTGATTCCAC
ATCAAGGATCATGAACCCACAAATCGTTGGGGAAGAGCACTACAGCACAGCACGTGAAGTACAAAGAATTCTACAACGTT
ACAAAGACCTTCAAGATATCATTGCCATCCTTGGTATGGACGAACTTTCTGAGGATGATAAAATCCTTGTGGCTCGTGCA
CGTCGTTTGGAAAAATTCCTTTCGCAACCATTCCATGTGGCAGAGCAGTTCACGGGTCGACCTGGTAAGTATGTGAAATT
GGAAGATACCATCCGTTCCTTCAAAGGAATCATCGAAGGTAAGTATGACTCACTTCCAGAGCAAGCATTCTATATGGTCG
GATCGATTGACGAAGTGATCGAAGCGGCAAAACAACTCAAAGGTTAA

Upstream 100 bases:

>100_bases
CGGATACAACCGAGTTCGTCAGGCAAAAATTACGCAGGAAATTTCAGAAATCGTAGGGGGAGCGGAAGCCATCTCCTAAC
AAAGGTCTTTCGGAGTATAT

Downstream 100 bases:

>100_bases
TTCGGATGAGTAAAGAACTGACTTTAACAGTCATCTCTCCAGACAAAATCCTTTACCAGGGAAAGGCAGAATCAGTGATT
CTGCCTGGAGCAGTGGGTTA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAISLQSTDGLKRGLEVTDTGIPI
SVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAPTYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVG
KTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDES
GSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSVQAIYVPADDLTDPAPATAFT
HLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEHYSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARA
RRLEKFLSQPFHVAEQFTGRPGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG

Sequences:

>Translated_468_residues
MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAISLQSTDGLKRGLEVTDTGIPI
SVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAPTYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVG
KTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDES
GSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSVQAIYVPADDLTDPAPATAFT
HLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEHYSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARA
RRLEKFLSQPFHVAEQFTGRPGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG
>Mature_468_residues
MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAISLQSTDGLKRGLEVTDTGIPI
SVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAPTYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVG
KTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDES
GSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSVQAIYVPADDLTDPAPATAFT
HLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEHYSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARA
RRLEKFLSQPFHVAEQFTGRPGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=469, Percent_Identity=66.7377398720682, Blast_Score=635, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=325, Percent_Identity=26.4615384615385, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI19913428, Length=360, Percent_Identity=25.8333333333333, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=360, Percent_Identity=25, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI50345984, Length=385, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4757810, Length=385, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1790170, Length=466, Percent_Identity=67.1673819742489, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=354, Percent_Identity=28.8135593220339, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790172, Length=313, Percent_Identity=26.1980830670927, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144756, Length=469, Percent_Identity=65.4584221748401, Blast_Score=619, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI17510931, Length=358, Percent_Identity=26.8156424581006, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=319, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=358, Percent_Identity=26.536312849162, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=369, Percent_Identity=25.2032520325203, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71988063, Length=369, Percent_Identity=25.2032520325203, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71988074, Length=341, Percent_Identity=24.3401759530792, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=67.5324675324675, Blast_Score=640, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=360, Percent_Identity=26.6666666666667, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=369, Percent_Identity=25.4742547425474, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=25.3218884120172, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24638766, Length=470, Percent_Identity=67.6595744680851, Blast_Score=637, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=470, Percent_Identity=64.0425531914894, Blast_Score=605, Evalue=1e-173,
Organism=Drosophila melanogaster, GI281361666, Length=404, Percent_Identity=25.7425742574257, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646341, Length=404, Percent_Identity=25.7425742574257, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136796, Length=404, Percent_Identity=25.7425742574257, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI20129479, Length=324, Percent_Identity=25.9259259259259, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=26.3975155279503, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583988, Length=324, Percent_Identity=26.5432098765432, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583986, Length=324, Percent_Identity=26.5432098765432, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24583984, Length=324, Percent_Identity=26.5432098765432, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24638768, Length=96, Percent_Identity=48.9583333333333, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658560, Length=299, Percent_Identity=28.0936454849498, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_LEPBA (B0SDA5)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961888.1
- ProteinModelPortal:   B0SDA5
- SMR:   B0SDA5
- GeneID:   6387550
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0778
- HOGENOM:   HBG565875
- OMA:   LTIAERF
- ProtClustDB:   PRK09280
- BioCyc:   LBIF355278:LBF_0778-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51123; Mature: 51123

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAIS
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEECCCEEEEEHHHHHHCCCCCEEEEE
LQSTDGLKRGLEVTDTGIPISVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAP
ECCCHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
TYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFS
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDES
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
GSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSV
CCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
QAIYVPADDLTDPAPATAFTHLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEH
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHH
YSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARARRLEKFLSQPFHVAEQFTGR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCC
PGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAIS
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEECCCEEEEEHHHHHHCCCCCEEEEE
LQSTDGLKRGLEVTDTGIPISVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAP
ECCCHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
TYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFS
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
VFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDES
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
GSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSV
CCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
QAIYVPADDLTDPAPATAFTHLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEH
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCHHH
YSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARARRLEKFLSQPFHVAEQFTGR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCC
PGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG
CCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA