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The map label for this gene is lipA [H]

Identifier: 183220187

GI number: 183220187

Start: 795232

End: 796143

Strand: Direct

Name: lipA [H]

Synonym: LEPBI_I0777

Alternate gene names: 183220187

Gene position: 795232-796143 (Clockwise)

Preceding gene: 183220186

Following gene: 183220188

Centisome position: 22.09

GC content: 44.52

Gene sequence:

>912_bases
ATGAAAAAGAAAATTGCGATCGGGTTTTTAGCGACCCTTCTCTCCTTCCCCACATCAGGTTTGTTTGCTGGTCCTTTGGA
TGGCCAATGCATCGCCCTTGTGCACGGTATTCTTGGATTTGACGACACGCAAGGGTTAGCTGGTGGACTCGTAAAGTATT
GGGGAGGCCTTGATGGTTACCTCCGTAGCCAAGGTGCAAAAGTAACAACACCTGGAAGTTCTGCTACGAATTCCATTCCC
GTTCGTGCAAGCCAAATCCAATCATCAGTCAATACTTGGATGACAGCAAACGGTTGTTCTAAGGTGCACCTCATGGGACA
CAGCCAAGGTGGACTTGTGATTCGTTATATGGTTTCCAATTTAGGATTTTCTGGAAAAACACAAACAGTGACTACAATCA
ACTCATTACACAAAGGAGCACCGATGGCTGACATCGTTCTTTCTGTGATCCCAAGTTGGTTACAACCATTTGCAAACTCA
GCTCTTGGATTACTTGCAAAATTGGTATACCGTGATGGTCGACCACAAGATGTCATCGCGATGGGAAAATCACTCACTGT
GAGTTATGTAAAAACATTCAATACAAATTCACCGAATAAATCGGGAATCAAATATTACTCCTATGGAAGCCAAATGGCTT
GGGCTGACCTCATCCAACACCCGATCATGGCACTCACTCACCCCATTACTTGGGCAGGTGGATTGTTTTATGGTTTAGGT
GGAGGAAATGATGGAGTGGTTCCGTTGAACTCCCAAAAATGGGGAACTTGGAAAGGAACACCAAACGCGTATTGGTTTGC
AACTGGAATTGACCACCTCCAAGCAACAAACTTGGCATGGAGTGGACAAAACTTTTTTGATGTCCAAGGTTGGTACCTAA
ACATCGCAAAGAATGCAAAAGCTGGATTGTAA

Upstream 100 bases:

>100_bases
GATGAAAAAGCGCTCGATGCCATGCGCAAACAACTCTTTGGGGAAGAGGCGGAAATCATCAAAAATGAGTTAGCCAAAAC
ATAGAAAGTTCAGGTGAAAT

Downstream 100 bases:

>100_bases
TCAGTCCATTTAAGAAAAAGCCGGTGTCACCCATCGGCTTTTTTTTGTACCCATCTCATTCACTTCTAATTTCCAATCGA
TTCTAGAATGTTTTCCAAAG

Product: putative triglyceride lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKKKIAIGFLATLLSFPTSGLFAGPLDGQCIALVHGILGFDDTQGLAGGLVKYWGGLDGYLRSQGAKVTTPGSSATNSIP
VRASQIQSSVNTWMTANGCSKVHLMGHSQGGLVIRYMVSNLGFSGKTQTVTTINSLHKGAPMADIVLSVIPSWLQPFANS
ALGLLAKLVYRDGRPQDVIAMGKSLTVSYVKTFNTNSPNKSGIKYYSYGSQMAWADLIQHPIMALTHPITWAGGLFYGLG
GGNDGVVPLNSQKWGTWKGTPNAYWFATGIDHLQATNLAWSGQNFFDVQGWYLNIAKNAKAGL

Sequences:

>Translated_303_residues
MKKKIAIGFLATLLSFPTSGLFAGPLDGQCIALVHGILGFDDTQGLAGGLVKYWGGLDGYLRSQGAKVTTPGSSATNSIP
VRASQIQSSVNTWMTANGCSKVHLMGHSQGGLVIRYMVSNLGFSGKTQTVTTINSLHKGAPMADIVLSVIPSWLQPFANS
ALGLLAKLVYRDGRPQDVIAMGKSLTVSYVKTFNTNSPNKSGIKYYSYGSQMAWADLIQHPIMALTHPITWAGGLFYGLG
GGNDGVVPLNSQKWGTWKGTPNAYWFATGIDHLQATNLAWSGQNFFDVQGWYLNIAKNAKAGL
>Mature_303_residues
MKKKIAIGFLATLLSFPTSGLFAGPLDGQCIALVHGILGFDDTQGLAGGLVKYWGGLDGYLRSQGAKVTTPGSSATNSIP
VRASQIQSSVNTWMTANGCSKVHLMGHSQGGLVIRYMVSNLGFSGKTQTVTTINSLHKGAPMADIVLSVIPSWLQPFANS
ALGLLAKLVYRDGRPQDVIAMGKSLTVSYVKTFNTNSPNKSGIKYYSYGSQMAWADLIQHPIMALTHPITWAGGLFYGLG
GGNDGVVPLNSQKWGTWKGTPNAYWFATGIDHLQATNLAWSGQNFFDVQGWYLNIAKNAKAGL

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=275, Percent_Identity=28.7272727272727, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32335; Mature: 32335

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKIAIGFLATLLSFPTSGLFAGPLDGQCIALVHGILGFDDTQGLAGGLVKYWGGLDGY
CCCCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
LRSQGAKVTTPGSSATNSIPVRASQIQSSVNTWMTANGCSKVHLMGHSQGGLVIRYMVSN
HHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCEEEEEHHHH
LGFSGKTQTVTTINSLHKGAPMADIVLSVIPSWLQPFANSALGLLAKLVYRDGRPQDVIA
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MGKSLTVSYVKTFNTNSPNKSGIKYYSYGSQMAWADLIQHPIMALTHPITWAGGLFYGLG
HCCCEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEECCCEEEECC
GGNDGVVPLNSQKWGTWKGTPNAYWFATGIDHLQATNLAWSGQNFFDVQGWYLNIAKNAK
CCCCCEEECCCCCCCCCCCCCCCEEEECCCCHHHHCCEEECCCCEEEECCEEEEEECCCC
AGL
CCC
>Mature Secondary Structure
MKKKIAIGFLATLLSFPTSGLFAGPLDGQCIALVHGILGFDDTQGLAGGLVKYWGGLDGY
CCCCHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
LRSQGAKVTTPGSSATNSIPVRASQIQSSVNTWMTANGCSKVHLMGHSQGGLVIRYMVSN
HHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCEEEEEHHHH
LGFSGKTQTVTTINSLHKGAPMADIVLSVIPSWLQPFANSALGLLAKLVYRDGRPQDVIA
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MGKSLTVSYVKTFNTNSPNKSGIKYYSYGSQMAWADLIQHPIMALTHPITWAGGLFYGLG
HCCCEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCEECCCEEEECC
GGNDGVVPLNSQKWGTWKGTPNAYWFATGIDHLQATNLAWSGQNFFDVQGWYLNIAKNAK
CCCCCEEECCCCCCCCCCCCCCCEEEECCCCHHHHCCEEECCCCEEEECCEEEEEECCCC
AGL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]