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The map label for this gene is rsbP [H]

Identifier: 183220178

GI number: 183220178

Start: 783654

End: 784766

Strand: Direct

Name: rsbP [H]

Synonym: LEPBI_I0767

Alternate gene names: 183220178

Gene position: 783654-784766 (Clockwise)

Preceding gene: 183220177

Following gene: 183220183

Centisome position: 21.77

GC content: 37.74

Gene sequence:

>1113_bases
ATGTCCGAGTATTCTTTTAAACCTGAAATTCTCATCATAGATGATGATACCGAAATCTGTGAAACTTTAGAATTGATCGT
GAATGGGTTAGGATACTTTGTCCGGTATTTCACTAATCCATTACAAGGATTGGAATACTTCGAAAGGGAAAAAAATCCCA
TCGTGTTTCTGGATGTAAACATGCCTCAAACTTCTGGATTGGAAGTTTTACCAAAAATCAAAGCAATCGATTCCAAAACA
CAAGTACTCATGATGACAGGAGAACACGACATCCAAACAGTTGTCTCTTCTTTGTATCATAGGGCATCCGATTTTATTTT
AAAACCATTCCATACAAAATCCATTGAGGCGGCCATTTCTAGAGCATTTGAGTATTATAATTTTCTAAAAGATAAAGAGT
CAATGGATGAGTCGATCAAACGAGACCTTCGTCTTGCCGCAAAAATCCAATCCAAAACGATGAATTTACCTACTTTAAAG
TATAAAATTCACTCTGAAATCAAACCAGTCAGCTTTGTCTCTGGAGATTTTTTCCAAGTGATCCCACTCGATGTTGACAG
AACATTGATCCTAATGGGTGATATTGAAGGCCATGGTGTGACTTCTGGACTCATTGCGATACTGATGACAACCATTCATA
AGGAACTTGCAAGAACGACAACAGTTGCCCCATCTGAGTTGTTGTCTCGATTGAATCGAGAATTATGTAATGAAATTGGA
ACTCATAGTATGACAGCGATTAGTATCGTAGTGAATCATACTGAAAAAAAAATTACTTATGCAAGGGGTGGACATCCTTT
CCCAATTGTATTCCCAAAAGACAGTCGAGCACCTATGATCTTACAAGACCAATCGGGACAAATTTTAGGAATCCTGAAAG
ATATGGAGTTTGCAGAAAACCAAATCCAAGTGGATTCTCGAGATATTCTATTTTTGTATTCGGACGGACTCCTTGCCTCA
AGCACTCATCCACTTGTACAATCGTTAGTGCAATTGCCCGCAGGAGAGAATCGATTTGACGCGATGAAAGCAGAAATCTC
CAATTATATCCAATATTTGGAATCTTCTTCTAAAGCATCGGATGACATATCTTATTTGCTTCTAGAGATTTAA

Upstream 100 bases:

>100_bases
TTCCATGAAGCGTATTTTCGCCGAGTGGATGAAGTAAAAGAAAAACTAAAATTCCAATTGGTCTCAAAATAAGCTTCTGA
AACTCCGATAATCATCGTAG

Downstream 100 bases:

>100_bases
GATACAAAACATTTGTTTTTGTTGCTTCCGTTAGAAATACATTCAGATTTTCTTTTGATTTGAATGTTCCTTTTAAAAAA
CCATCTTTCCATTGCTTTCG

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSEYSFKPEILIIDDDTEICETLELIVNGLGYFVRYFTNPLQGLEYFEREKNPIVFLDVNMPQTSGLEVLPKIKAIDSKT
QVLMMTGEHDIQTVVSSLYHRASDFILKPFHTKSIEAAISRAFEYYNFLKDKESMDESIKRDLRLAAKIQSKTMNLPTLK
YKIHSEIKPVSFVSGDFFQVIPLDVDRTLILMGDIEGHGVTSGLIAILMTTIHKELARTTTVAPSELLSRLNRELCNEIG
THSMTAISIVVNHTEKKITYARGGHPFPIVFPKDSRAPMILQDQSGQILGILKDMEFAENQIQVDSRDILFLYSDGLLAS
STHPLVQSLVQLPAGENRFDAMKAEISNYIQYLESSSKASDDISYLLLEI

Sequences:

>Translated_370_residues
MSEYSFKPEILIIDDDTEICETLELIVNGLGYFVRYFTNPLQGLEYFEREKNPIVFLDVNMPQTSGLEVLPKIKAIDSKT
QVLMMTGEHDIQTVVSSLYHRASDFILKPFHTKSIEAAISRAFEYYNFLKDKESMDESIKRDLRLAAKIQSKTMNLPTLK
YKIHSEIKPVSFVSGDFFQVIPLDVDRTLILMGDIEGHGVTSGLIAILMTTIHKELARTTTVAPSELLSRLNRELCNEIG
THSMTAISIVVNHTEKKITYARGGHPFPIVFPKDSRAPMILQDQSGQILGILKDMEFAENQIQVDSRDILFLYSDGLLAS
STHPLVQSLVQLPAGENRFDAMKAEISNYIQYLESSSKASDDISYLLLEI
>Mature_369_residues
SEYSFKPEILIIDDDTEICETLELIVNGLGYFVRYFTNPLQGLEYFEREKNPIVFLDVNMPQTSGLEVLPKIKAIDSKTQ
VLMMTGEHDIQTVVSSLYHRASDFILKPFHTKSIEAAISRAFEYYNFLKDKESMDESIKRDLRLAAKIQSKTMNLPTLKY
KIHSEIKPVSFVSGDFFQVIPLDVDRTLILMGDIEGHGVTSGLIAILMTTIHKELARTTTVAPSELLSRLNRELCNEIGT
HSMTAISIVVNHTEKKITYARGGHPFPIVFPKDSRAPMILQDQSGQILGILKDMEFAENQIQVDSRDILFLYSDGLLASS
THPLVQSLVQLPAGENRFDAMKAEISNYIQYLESSSKASDDISYLLLEI

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=29.6610169491525, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=23.8461538461538, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 41765; Mature: 41633

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYSFKPEILIIDDDTEICETLELIVNGLGYFVRYFTNPLQGLEYFEREKNPIVFLDVN
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECC
MPQTSGLEVLPKIKAIDSKTQVLMMTGEHDIQTVVSSLYHRASDFILKPFHTKSIEAAIS
CCCCCCCHHCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
RAFEYYNFLKDKESMDESIKRDLRLAAKIQSKTMNLPTLKYKIHSEIKPVSFVSGDFFQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCEEE
IPLDVDRTLILMGDIEGHGVTSGLIAILMTTIHKELARTTTVAPSELLSRLNRELCNEIG
EEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
THSMTAISIVVNHTEKKITYARGGHPFPIVFPKDSRAPMILQDQSGQILGILKDMEFAEN
CCCEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCCEEEECCCCCEEEEEHHHHHHCC
QIQVDSRDILFLYSDGLLASSTHPLVQSLVQLPAGENRFDAMKAEISNYIQYLESSSKAS
CEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DDISYLLLEI
CCCEEEEEEC
>Mature Secondary Structure 
SEYSFKPEILIIDDDTEICETLELIVNGLGYFVRYFTNPLQGLEYFEREKNPIVFLDVN
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEECC
MPQTSGLEVLPKIKAIDSKTQVLMMTGEHDIQTVVSSLYHRASDFILKPFHTKSIEAAIS
CCCCCCCHHCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
RAFEYYNFLKDKESMDESIKRDLRLAAKIQSKTMNLPTLKYKIHSEIKPVSFVSGDFFQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCEEE
IPLDVDRTLILMGDIEGHGVTSGLIAILMTTIHKELARTTTVAPSELLSRLNRELCNEIG
EEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
THSMTAISIVVNHTEKKITYARGGHPFPIVFPKDSRAPMILQDQSGQILGILKDMEFAEN
CCCEEEEEEEEECCCCEEEEECCCCCCEEEECCCCCCCEEEECCCCCEEEEEHHHHHHCC
QIQVDSRDILFLYSDGLLASSTHPLVQSLVQLPAGENRFDAMKAEISNYIQYLESSSKAS
CEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DDISYLLLEI
CCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]