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The map label for this gene is ccmF [H]

Identifier: 183220136

GI number: 183220136

Start: 737934

End: 740135

Strand: Reverse

Name: ccmF [H]

Synonym: LEPBI_I0724

Alternate gene names: 183220136

Gene position: 740135-737934 (Counterclockwise)

Preceding gene: 183220137

Following gene: 183220135

Centisome position: 20.56

GC content: 40.1

Gene sequence:

>2202_bases
ATGAATAATTTAGGGACCATCTTACTTTCAGCATCACTCGCTATTTTAATTTTTTCCGCCTTACAAACGATCTACGGAAT
ATTATATTCACAAAGAAAAGGAGTCGAACTTGGTCGTTTGGCTCTCATGACAAATCCATTTGTCATCGTATTAGCATTTA
TCGTTTTACTCACACAACTCGTTCGATCTGACTATAGCAACTATTATGTGGTCATGCATTCAAGCGAACACTTACCTTTA
TTTTATAAAATGACTTCCATCTGGTCTGGATCTTCTGGAAGTTTACTTTTTTGGAATTTGATCTTAAATGTGTTTACCTT
TATTGTTTTGTGGCAAACACGAAAGTCGATCGAAGACCGAATCCCAATGATGAATCTTATCCTTGCGGTATTGTCGGGAT
TTTTTAGTTTCCTTGCTGTGTTTTATGGGGATGCCCAACCGTTTCGTGAATTTGTTCCCGAAGCAGCTGCGGGCAGAGGA
CTAAACCCCCTTCTCCAACATTGGGCAATGATCATCCACCCACCAATCCTTTACATTGGTTATGTGAGTATATCCATTCC
ATTTGCCATAGCCATGTCAGCTCTTGTTTCAGGTCAACTCTCTGAGGATTGGATGAAGTTCATTCGGAAATGGACTTTGT
TTTCTTGGTTTTTCTTAGGAACAGGAATTCTACTTGGATCCAAATGGGCCTACGAAGAGTTAGGTTGGGGAGGGTATTGG
GCATGGGATCCAGTGGAAAATGCATCCTTGATGCCTTGGTTACTCACAAGTGCCTTTGTCCATTCCGTTGTCATCCAAGA
ACGTAGAGGGATGTTAAAGTTTTGGAATATGTTGCTTGTGATCCTTGCCTTCCATTTTAGTTTGCTTGGAACTTGGATCA
CACGTTCGGGAGTACTCGAAGGTCCACATAGTTTTTCCAAATCCACCATCGGAACACCTTTTATTGTTTATATCATCGGT
AGTTTTTTATTCTTCACAGGATTTGTGATTTACCGAAGGAAAGAACTCACACCAGAAAGAAACTTAGAGGCCATCACTTC
CAAAGAAGGGAGTTTTTTACTCAATAATTTTCTTTTGGTACTTTCGACGGCTGCCATTTTACTCGGTGTATTTTCTCCGC
TTTTGTATGGAAAAGAATTTAAAGCACCTTGGTTCAATTCTTGGGGAGTTCCTGCCGGGATCTTTTTATTATTGCTGATG
GGATCGGCACCTCTCCTTGCTTGGAGAAAGGGAGCAGGATCTGTCTTTTTATCCACATTACTCAAACCATTCCTCTTTGG
AATTTTTGGTGGGGGAATTTACATCCTATTTTATTCCCAAAACTTTACCAAACCCGACAGTAAGTATGGGGACGTCCTTG
CAGAAGTGTATTCGGTTCTCACTGTAGGCATCGGAATGTTTACCATTGCGGGGATTGTGCAAGAATACTACCGCGGGATC
AAAGCAAGAAAAGAAGAACACAAAGATGAATCTTTGTTACGAGCCGCCTTAAACCTAATGTTAAAAAACAAACGGAGGTA
TGGTGGATATTTAGTGCACTTCTCACTGGTTCTCATCTTCATCGGATATGCAGGGAATGCCTTTAAGATCAATACCTCTG
TCCGTTTTTTTTATGAACTACAACCTCCTACTTCTGAAGAAATCATCTACCAATCCATCGACAAGGCAATGATTGGTGGT
TACCAAATCGAAGCATCCACATTAAAAATCAAACCCGTCCTCATTTCTGGACTCGGTGGTGAACCTAACATTCAAAATGT
GATCGTTTCTCAGGAAGCAAGTTATGGAATTTATCGTGGATTGGAAAAAATTGCAACTCTCGAGACTGAAAGAAGATTTT
ATCCACAAATTTCCCACCTAACAGGTGATTTCGAAACACATATCCCAACAAGTGAACCCGCCATCCATTCCATGGCAAAA
GAAGACTTTTACATCCAACTTGGTGCAATCGAAACTTCTGATTTAAAATCGGAAAACCCTGACCTACCGCTGATGTTTAT
GCAGTATTATTTTACCCCAGGAAGCCAAACTGATAAACTCAAATCCTTCTTAAACTTCCCAAGGCAAATTGTAGCAAACT
TAGAAGTTTGGATCAACCCACTTGTGAAATTGATTTGGATTGGTTCCTTATTGTATTTTTTATCTGGTATCTTTTTGTTA
CTCCCCATCGGAGAAAAAAAGAATCGAACAAAGGAGAGTTAG

Upstream 100 bases:

>100_bases
GGGCAAGGGTGGATGGAAAACTGGAACGTGGAGTACTTGTTTCAAACCATGTGGAAGCAAAATGTGCCTCCAAATATGAA
GCTGGGTATGCAGAGGAAAA

Downstream 100 bases:

>100_bases
GTATGACCTATCGAATCATATTGGGAATTCTTTTGTTTTTTGGATCTGCTAGTGTTTTATTTTCACAAAAAACAACAACC
AACCTGAAAGAAGAACAACA

Product: cytochrome c-type biogenesis protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MNNLGTILLSASLAILIFSALQTIYGILYSQRKGVELGRLALMTNPFVIVLAFIVLLTQLVRSDYSNYYVVMHSSEHLPL
FYKMTSIWSGSSGSLLFWNLILNVFTFIVLWQTRKSIEDRIPMMNLILAVLSGFFSFLAVFYGDAQPFREFVPEAAAGRG
LNPLLQHWAMIIHPPILYIGYVSISIPFAIAMSALVSGQLSEDWMKFIRKWTLFSWFFLGTGILLGSKWAYEELGWGGYW
AWDPVENASLMPWLLTSAFVHSVVIQERRGMLKFWNMLLVILAFHFSLLGTWITRSGVLEGPHSFSKSTIGTPFIVYIIG
SFLFFTGFVIYRRKELTPERNLEAITSKEGSFLLNNFLLVLSTAAILLGVFSPLLYGKEFKAPWFNSWGVPAGIFLLLLM
GSAPLLAWRKGAGSVFLSTLLKPFLFGIFGGGIYILFYSQNFTKPDSKYGDVLAEVYSVLTVGIGMFTIAGIVQEYYRGI
KARKEEHKDESLLRAALNLMLKNKRRYGGYLVHFSLVLIFIGYAGNAFKINTSVRFFYELQPPTSEEIIYQSIDKAMIGG
YQIEASTLKIKPVLISGLGGEPNIQNVIVSQEASYGIYRGLEKIATLETERRFYPQISHLTGDFETHIPTSEPAIHSMAK
EDFYIQLGAIETSDLKSENPDLPLMFMQYYFTPGSQTDKLKSFLNFPRQIVANLEVWINPLVKLIWIGSLLYFLSGIFLL
LPIGEKKNRTKES

Sequences:

>Translated_733_residues
MNNLGTILLSASLAILIFSALQTIYGILYSQRKGVELGRLALMTNPFVIVLAFIVLLTQLVRSDYSNYYVVMHSSEHLPL
FYKMTSIWSGSSGSLLFWNLILNVFTFIVLWQTRKSIEDRIPMMNLILAVLSGFFSFLAVFYGDAQPFREFVPEAAAGRG
LNPLLQHWAMIIHPPILYIGYVSISIPFAIAMSALVSGQLSEDWMKFIRKWTLFSWFFLGTGILLGSKWAYEELGWGGYW
AWDPVENASLMPWLLTSAFVHSVVIQERRGMLKFWNMLLVILAFHFSLLGTWITRSGVLEGPHSFSKSTIGTPFIVYIIG
SFLFFTGFVIYRRKELTPERNLEAITSKEGSFLLNNFLLVLSTAAILLGVFSPLLYGKEFKAPWFNSWGVPAGIFLLLLM
GSAPLLAWRKGAGSVFLSTLLKPFLFGIFGGGIYILFYSQNFTKPDSKYGDVLAEVYSVLTVGIGMFTIAGIVQEYYRGI
KARKEEHKDESLLRAALNLMLKNKRRYGGYLVHFSLVLIFIGYAGNAFKINTSVRFFYELQPPTSEEIIYQSIDKAMIGG
YQIEASTLKIKPVLISGLGGEPNIQNVIVSQEASYGIYRGLEKIATLETERRFYPQISHLTGDFETHIPTSEPAIHSMAK
EDFYIQLGAIETSDLKSENPDLPLMFMQYYFTPGSQTDKLKSFLNFPRQIVANLEVWINPLVKLIWIGSLLYFLSGIFLL
LPIGEKKNRTKES
>Mature_733_residues
MNNLGTILLSASLAILIFSALQTIYGILYSQRKGVELGRLALMTNPFVIVLAFIVLLTQLVRSDYSNYYVVMHSSEHLPL
FYKMTSIWSGSSGSLLFWNLILNVFTFIVLWQTRKSIEDRIPMMNLILAVLSGFFSFLAVFYGDAQPFREFVPEAAAGRG
LNPLLQHWAMIIHPPILYIGYVSISIPFAIAMSALVSGQLSEDWMKFIRKWTLFSWFFLGTGILLGSKWAYEELGWGGYW
AWDPVENASLMPWLLTSAFVHSVVIQERRGMLKFWNMLLVILAFHFSLLGTWITRSGVLEGPHSFSKSTIGTPFIVYIIG
SFLFFTGFVIYRRKELTPERNLEAITSKEGSFLLNNFLLVLSTAAILLGVFSPLLYGKEFKAPWFNSWGVPAGIFLLLLM
GSAPLLAWRKGAGSVFLSTLLKPFLFGIFGGGIYILFYSQNFTKPDSKYGDVLAEVYSVLTVGIGMFTIAGIVQEYYRGI
KARKEEHKDESLLRAALNLMLKNKRRYGGYLVHFSLVLIFIGYAGNAFKINTSVRFFYELQPPTSEEIIYQSIDKAMIGG
YQIEASTLKIKPVLISGLGGEPNIQNVIVSQEASYGIYRGLEKIATLETERRFYPQISHLTGDFETHIPTSEPAIHSMAK
EDFYIQLGAIETSDLKSENPDLPLMFMQYYFTPGSQTDKLKSFLNFPRQIVANLEVWINPLVKLIWIGSLLYFLSGIFLL
LPIGEKKNRTKES

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=422, Percent_Identity=36.4928909952607, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790511, Length=346, Percent_Identity=34.1040462427746, Blast_Score=192, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 82854; Mature: 82854

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLGTILLSASLAILIFSALQTIYGILYSQRKGVELGRLALMTNPFVIVLAFIVLLTQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHH
VRSDYSNYYVVMHSSEHLPLFYKMTSIWSGSSGSLLFWNLILNVFTFIVLWQTRKSIEDR
HHCCCCCEEEEEECCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IPMMNLILAVLSGFFSFLAVFYGDAQPFREFVPEAAAGRGLNPLLQHWAMIIHPPILYIG
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHCCHHHHHH
YVSISIPFAIAMSALVSGQLSEDWMKFIRKWTLFSWFFLGTGILLGSKWAYEELGWGGYW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEE
AWDPVENASLMPWLLTSAFVHSVVIQERRGMLKFWNMLLVILAFHFSLLGTWITRSGVLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GPHSFSKSTIGTPFIVYIIGSFLFFTGFVIYRRKELTPERNLEAITSKEGSFLLNNFLLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHH
LSTAAILLGVFSPLLYGKEFKAPWFNSWGVPAGIFLLLLMGSAPLLAWRKGAGSVFLSTL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHECCCCHHHHHHHH
LKPFLFGIFGGGIYILFYSQNFTKPDSKYGDVLAEVYSVLTVGIGMFTIAGIVQEYYRGI
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARKEEHKDESLLRAALNLMLKNKRRYGGYLVHFSLVLIFIGYAGNAFKINTSVRFFYEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCEEEEECEEEEEEEE
QPPTSEEIIYQSIDKAMIGGYQIEASTLKIKPVLISGLGGEPNIQNVIVSQEASYGIYRG
CCCCHHHHHHHHHHHHHHCCEEEEECEEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHH
LEKIATLETERRFYPQISHLTGDFETHIPTSEPAIHSMAKEDFYIQLGAIETSDLKSENP
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEECEECCCCCCCCC
DLPLMFMQYYFTPGSQTDKLKSFLNFPRQIVANLEVWINPLVKLIWIGSLLYFLSGIFLL
CCCEEEHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LPIGEKKNRTKES
EECCCCCCCCCCC
>Mature Secondary Structure
MNNLGTILLSASLAILIFSALQTIYGILYSQRKGVELGRLALMTNPFVIVLAFIVLLTQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHH
VRSDYSNYYVVMHSSEHLPLFYKMTSIWSGSSGSLLFWNLILNVFTFIVLWQTRKSIEDR
HHCCCCCEEEEEECCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IPMMNLILAVLSGFFSFLAVFYGDAQPFREFVPEAAAGRGLNPLLQHWAMIIHPPILYIG
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHCCHHHHHH
YVSISIPFAIAMSALVSGQLSEDWMKFIRKWTLFSWFFLGTGILLGSKWAYEELGWGGYW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEE
AWDPVENASLMPWLLTSAFVHSVVIQERRGMLKFWNMLLVILAFHFSLLGTWITRSGVLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GPHSFSKSTIGTPFIVYIIGSFLFFTGFVIYRRKELTPERNLEAITSKEGSFLLNNFLLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHH
LSTAAILLGVFSPLLYGKEFKAPWFNSWGVPAGIFLLLLMGSAPLLAWRKGAGSVFLSTL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHECCCCHHHHHHHH
LKPFLFGIFGGGIYILFYSQNFTKPDSKYGDVLAEVYSVLTVGIGMFTIAGIVQEYYRGI
HHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARKEEHKDESLLRAALNLMLKNKRRYGGYLVHFSLVLIFIGYAGNAFKINTSVRFFYEL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCEEEEECEEEEEEEE
QPPTSEEIIYQSIDKAMIGGYQIEASTLKIKPVLISGLGGEPNIQNVIVSQEASYGIYRG
CCCCHHHHHHHHHHHHHHCCEEEEECEEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHH
LEKIATLETERRFYPQISHLTGDFETHIPTSEPAIHSMAKEDFYIQLGAIETSDLKSENP
HHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEECEECCCCCCCCC
DLPLMFMQYYFTPGSQTDKLKSFLNFPRQIVANLEVWINPLVKLIWIGSLLYFLSGIFLL
CCCEEEHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LPIGEKKNRTKES
EECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]