Click here to switch to the map view.

The map label for this gene is avtA [H]

Identifier: 183220107

GI number: 183220107

Start: 705324

End: 706598

Strand: Reverse

Name: avtA [H]

Synonym: LEPBI_I0695

Alternate gene names: 183220107

Gene position: 706598-705324 (Counterclockwise)

Preceding gene: 183220110

Following gene: 183220106

Centisome position: 19.63

GC content: 43.69

Gene sequence:

>1275_bases
ATGACCGAAACCATGGACCAAATTTACTCCTCCTGGGCCCACCGACTCCGCCAAAACCAAGGGATTCGTTCTCTGATGGA
AGATTTAGGCCAAGTCACAGGCCATCCTGATGAAATCTTACTCGGTGGCGGGAACCCCGCCCATATCCCAGAAGCAGAGG
CCATTTTTCGGGATATATTTTTAAGTTTGGCAAAAGAACCATCCCTTACCTCTCTTCTCGGTGACTACCAAGCACCGATT
GGAAACGACCACTTCCGAGAACTGGCTGCTGAATCCCTCTCTCCCTACCTCGGTGCGAATCTAAAAAAAGAAAACATCGC
TTTTTTGAACGGAAGCCAAAATGCCTATTCATTCCTTCTCAACCTCCATTCCGGTCCAATGGCAGATGGTAGTTTTCAAA
AAATTCTTTTGCCAATTGTTCCAGAATACATTGGTTATGCGGACCAAACAATCACAAACGATGTTTTTATTGCAACACCA
CCCAATGTAGTGCCGACAGGAAAACATCGTTTCCGTTACGAATTGAACAAAGAGGCATTTGATTTAGATGGTGTTGGTGT
TCTTGCGATTTCGAGACCAACCAATCCAACAGGGAATATTCTTTCCCTTTCCGATTTGGAATGGATGGAAGAAAGAACGA
GAAAACAAAACATTCCCTTTCTCATTGACCTCGCGTATGGAAACCCATTTCCCAATTTGATTGGAAACGAAGCTCCGATC
CATTATGAAAAAGGTCGTACCCTTTCCTTAAGTTTTTCAAAAATTGGATTGCCTGGTGTTCGTTTGGGAATCGTGGTTTC
CGATGAAGAAACAATTGAAACCCTTTCTTCCTTTGCTGCTGTTGGGAATCTTGCCGTTGGGAACTTGGGACTGTACATGA
TGGAGATCCTCTTCCAAAAGAAGGTCCTTCCCGAATTATCAAAACACATCTTACGTCCGTTCTATGAATCAAAACGCGAT
CTTGCGCTTGGCGTATTCACGACAACCTTTGAAAAAATGGGTGTGGATTACGAAATCCACGATCCGATGGGTGGGTTTTT
CCTATGGGTCAGGTTCCCATCACTTTCCATCACCAATCATGAATTGTATCACCTTTGTAAAGATAAACGGCTCTTCATTG
TATCAGGACATTATTTCTTTCCAGGCTTAAACTCTGATTTTTCGCATACCAAAGATTGCATACGTTTGACATATTGCCGT
AAGGAAGAAGAATTAGCCAGGGGAGCCCAAATCCTAGCAGAAATTGTGGCCTCTCACCAGGCGAAATCCAAATGA

Upstream 100 bases:

>100_bases
TAACCCATTTACGAATTATGTCACTTCATTTTTCGAAATGCGAACATAATTTTAGAATTTCCAAGGAAAATTGGTTCTGA
GTAGACGAAGTTTGCAAAAA

Downstream 100 bases:

>100_bases
GCGAAGATAGTATCGATTTATCTGACACAGTCTTAGAGAACCCTTCATCCCGTGATGAAAATTCTACCGACAGGCCTTCT
GCTCAATCCTATATTTTTTT

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTETMDQIYSSWAHRLRQNQGIRSLMEDLGQVTGHPDEILLGGGNPAHIPEAEAIFRDIFLSLAKEPSLTSLLGDYQAPI
GNDHFRELAAESLSPYLGANLKKENIAFLNGSQNAYSFLLNLHSGPMADGSFQKILLPIVPEYIGYADQTITNDVFIATP
PNVVPTGKHRFRYELNKEAFDLDGVGVLAISRPTNPTGNILSLSDLEWMEERTRKQNIPFLIDLAYGNPFPNLIGNEAPI
HYEKGRTLSLSFSKIGLPGVRLGIVVSDEETIETLSSFAAVGNLAVGNLGLYMMEILFQKKVLPELSKHILRPFYESKRD
LALGVFTTTFEKMGVDYEIHDPMGGFFLWVRFPSLSITNHELYHLCKDKRLFIVSGHYFFPGLNSDFSHTKDCIRLTYCR
KEEELARGAQILAEIVASHQAKSK

Sequences:

>Translated_424_residues
MTETMDQIYSSWAHRLRQNQGIRSLMEDLGQVTGHPDEILLGGGNPAHIPEAEAIFRDIFLSLAKEPSLTSLLGDYQAPI
GNDHFRELAAESLSPYLGANLKKENIAFLNGSQNAYSFLLNLHSGPMADGSFQKILLPIVPEYIGYADQTITNDVFIATP
PNVVPTGKHRFRYELNKEAFDLDGVGVLAISRPTNPTGNILSLSDLEWMEERTRKQNIPFLIDLAYGNPFPNLIGNEAPI
HYEKGRTLSLSFSKIGLPGVRLGIVVSDEETIETLSSFAAVGNLAVGNLGLYMMEILFQKKVLPELSKHILRPFYESKRD
LALGVFTTTFEKMGVDYEIHDPMGGFFLWVRFPSLSITNHELYHLCKDKRLFIVSGHYFFPGLNSDFSHTKDCIRLTYCR
KEEELARGAQILAEIVASHQAKSK
>Mature_423_residues
TETMDQIYSSWAHRLRQNQGIRSLMEDLGQVTGHPDEILLGGGNPAHIPEAEAIFRDIFLSLAKEPSLTSLLGDYQAPIG
NDHFRELAAESLSPYLGANLKKENIAFLNGSQNAYSFLLNLHSGPMADGSFQKILLPIVPEYIGYADQTITNDVFIATPP
NVVPTGKHRFRYELNKEAFDLDGVGVLAISRPTNPTGNILSLSDLEWMEERTRKQNIPFLIDLAYGNPFPNLIGNEAPIH
YEKGRTLSLSFSKIGLPGVRLGIVVSDEETIETLSSFAAVGNLAVGNLGLYMMEILFQKKVLPELSKHILRPFYESKRDL
ALGVFTTTFEKMGVDYEIHDPMGGFFLWVRFPSLSITNHELYHLCKDKRLFIVSGHYFFPGLNSDFSHTKDCIRLTYCRK
EEELARGAQILAEIVASHQAKSK

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=416, Percent_Identity=35.5769230769231, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47438; Mature: 47307

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETMDQIYSSWAHRLRQNQGIRSLMEDLGQVTGHPDEILLGGGNPAHIPEAEAIFRDIF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHH
LSLAKEPSLTSLLGDYQAPIGNDHFRELAAESLSPYLGANLKKENIAFLNGSQNAYSFLL
HHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCEEEEE
NLHSGPMADGSFQKILLPIVPEYIGYADQTITNDVFIATPPNVVPTGKHRFRYELNKEAF
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCEE
DLDGVGVLAISRPTNPTGNILSLSDLEWMEERTRKQNIPFLIDLAYGNPFPNLIGNEAPI
CCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCCE
HYEKGRTLSLSFSKIGLPGVRLGIVVSDEETIETLSSFAAVGNLAVGNLGLYMMEILFQK
EECCCCEEEEEHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KVLPELSKHILRPFYESKRDLALGVFTTTFEKMGVDYEIHDPMGGFFLWVRFPSLSITNH
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCH
ELYHLCKDKRLFIVSGHYFFPGLNSDFSHTKDCIRLTYCRKEEELARGAQILAEIVASHQ
HHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AKSK
CCCC
>Mature Secondary Structure 
TETMDQIYSSWAHRLRQNQGIRSLMEDLGQVTGHPDEILLGGGNPAHIPEAEAIFRDIF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHH
LSLAKEPSLTSLLGDYQAPIGNDHFRELAAESLSPYLGANLKKENIAFLNGSQNAYSFLL
HHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCCCCCEEEEECCCCCEEEEE
NLHSGPMADGSFQKILLPIVPEYIGYADQTITNDVFIATPPNVVPTGKHRFRYELNKEAF
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCEE
DLDGVGVLAISRPTNPTGNILSLSDLEWMEERTRKQNIPFLIDLAYGNPFPNLIGNEAPI
CCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCCCE
HYEKGRTLSLSFSKIGLPGVRLGIVVSDEETIETLSSFAAVGNLAVGNLGLYMMEILFQK
EECCCCEEEEEHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KVLPELSKHILRPFYESKRDLALGVFTTTFEKMGVDYEIHDPMGGFFLWVRFPSLSITNH
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCCCH
ELYHLCKDKRLFIVSGHYFFPGLNSDFSHTKDCIRLTYCRKEEELARGAQILAEIVASHQ
HHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AKSK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]