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The map label for this gene is dprE1 [H]

Identifier: 183219956

GI number: 183219956

Start: 534732

End: 536177

Strand: Reverse

Name: dprE1 [H]

Synonym: LEPBI_I0538

Alternate gene names: 183219956

Gene position: 536177-534732 (Counterclockwise)

Preceding gene: 183219957

Following gene: 183219948

Centisome position: 14.9

GC content: 36.17

Gene sequence:

>1446_bases
ATGGTAACAAAAAAAACAAAATCCATTCCTAGTATCAAAGTTCCTCATAAAGAAAAGGTAGAAGCATGGGGAATGAGTTC
TTTTTCCATGTCACCAGTGTTTCGTCCTGAAACGGAAGAAGAGATCAAAGAACTTTTTATTTGGGCAAACCAAACTGGCA
CCAAAGTTGCGTTACGTGGTGGTGGATGTAGTTATGGTGATGCATCTTCGAATAATGATGGAATTGTTTTAGATCTAACT
CGTTTCAACAAGGTTTTGGATTTTAATCTTAAAACAGGTGTGATGACGGTTCAATCAGGTGCTAGGATCAAAGACCTTTG
GGAAACAGGTATTGAAAATGGATTTTGGCCTCCAGTGGTTTCAGGCACAATGATGCCTACTCTAGGAGGAGCCCTTTCCA
TGAACATTCATGGAAAAAATAACTTCAAAGTGGGAACCATCGGGGAACACATCAAAGAATTTACATTTTTAACAGCAAAA
GGTGATATTCTAGTTTGTTCTCCGAAAAAAAATTCTGATCTATTTTATTCCGCAATATCCGGCTTTGGTATGTTAGGTTG
TTTTTTAACGGTTCAGATCAAGATGAAACCAATCTATTCTGGAAAAATGAAAATTGATCCAGTATATGTTCGTAACTTTG
ACGAATTATTCGAATATTTTGAAGAACATTACAAAACAGCTGATTATTTAGTAGGTTGGATTGATGCATTTGCTTCAGGT
AAGGCTCTTGGCCGGGGCCAAATCCACAAAGCGACGAACCTGAAAAAAGGGGAAGATCCAGATTTTCCTGGGAATTGTTT
ATTAGAAAGACAACATCTACCGACACGTTTGTTTTATCTGATCCCTAAAAAATGGATGTGGATCCTGATGCGACCATTCA
GTTTCAATTTTGGAATGCGAATGATCAATTTGGCAAAATGTATCGCAAGTATCTTGGTCAACAATAAGACTTATTACCAA
GGACATGCCGAGTATGCTTTTTTATTAGACTATGTTCCAAATTGGAAATTTGTTTATAAACCTGGTGCGATGATCCAATA
CCAAGTGTTTATTCCAAAAGAGAACGCAAAACAAGCGTTTCGCGAAATTTTTACAAAATGCCAAGATCGTGGGATCGTGA
ATTATTTATCTGTCTTTAAAAAACACAAACCTGATCCTTTTTTACTCACTCATGCGGTAGATGGATTTTCGATGGCTATG
GACTTCCCTGTCACAAAAAGGAATCGAGAAAAACTTTGGTCACTCTGTTATGAGTTGGATGAAATTGTTTTAAAACACAA
AGGAAGGTTTTATTTTGCAAAGGATTCAACTCTTCGTAAACGTGTAATGGAATCTTATTTTCCAAAGGATAACTTAAAGA
AGTTTTATACTTTAAAGAAAAAATACGATCCGAAAGGAATTTTACAAACCGATTTGTATAAACGCGTATTTTTACAGTCA
GTCTGA

Upstream 100 bases:

>100_bases
AATGGTAAGGATGAGGCTTTTGTTCCAGGAATTTGGGCATTAGTAGCACTCATCATCCGCAACATTCCCAATTTTATCTT
CAAAAAACTGAGTATATAAT

Downstream 100 bases:

>100_bases
TGAAACTTTTTAAACTTTAAATCACAATCTAACCTTCCTATCTTTTTTAAGATGGGGAGGTTCCAATCCACTTAGATCAA
ATTTCTACTATTAAAAACAA

Product: putative FAD-linked oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MVTKKTKSIPSIKVPHKEKVEAWGMSSFSMSPVFRPETEEEIKELFIWANQTGTKVALRGGGCSYGDASSNNDGIVLDLT
RFNKVLDFNLKTGVMTVQSGARIKDLWETGIENGFWPPVVSGTMMPTLGGALSMNIHGKNNFKVGTIGEHIKEFTFLTAK
GDILVCSPKKNSDLFYSAISGFGMLGCFLTVQIKMKPIYSGKMKIDPVYVRNFDELFEYFEEHYKTADYLVGWIDAFASG
KALGRGQIHKATNLKKGEDPDFPGNCLLERQHLPTRLFYLIPKKWMWILMRPFSFNFGMRMINLAKCIASILVNNKTYYQ
GHAEYAFLLDYVPNWKFVYKPGAMIQYQVFIPKENAKQAFREIFTKCQDRGIVNYLSVFKKHKPDPFLLTHAVDGFSMAM
DFPVTKRNREKLWSLCYELDEIVLKHKGRFYFAKDSTLRKRVMESYFPKDNLKKFYTLKKKYDPKGILQTDLYKRVFLQS
V

Sequences:

>Translated_481_residues
MVTKKTKSIPSIKVPHKEKVEAWGMSSFSMSPVFRPETEEEIKELFIWANQTGTKVALRGGGCSYGDASSNNDGIVLDLT
RFNKVLDFNLKTGVMTVQSGARIKDLWETGIENGFWPPVVSGTMMPTLGGALSMNIHGKNNFKVGTIGEHIKEFTFLTAK
GDILVCSPKKNSDLFYSAISGFGMLGCFLTVQIKMKPIYSGKMKIDPVYVRNFDELFEYFEEHYKTADYLVGWIDAFASG
KALGRGQIHKATNLKKGEDPDFPGNCLLERQHLPTRLFYLIPKKWMWILMRPFSFNFGMRMINLAKCIASILVNNKTYYQ
GHAEYAFLLDYVPNWKFVYKPGAMIQYQVFIPKENAKQAFREIFTKCQDRGIVNYLSVFKKHKPDPFLLTHAVDGFSMAM
DFPVTKRNREKLWSLCYELDEIVLKHKGRFYFAKDSTLRKRVMESYFPKDNLKKFYTLKKKYDPKGILQTDLYKRVFLQS
V
>Mature_481_residues
MVTKKTKSIPSIKVPHKEKVEAWGMSSFSMSPVFRPETEEEIKELFIWANQTGTKVALRGGGCSYGDASSNNDGIVLDLT
RFNKVLDFNLKTGVMTVQSGARIKDLWETGIENGFWPPVVSGTMMPTLGGALSMNIHGKNNFKVGTIGEHIKEFTFLTAK
GDILVCSPKKNSDLFYSAISGFGMLGCFLTVQIKMKPIYSGKMKIDPVYVRNFDELFEYFEEHYKTADYLVGWIDAFASG
KALGRGQIHKATNLKKGEDPDFPGNCLLERQHLPTRLFYLIPKKWMWILMRPFSFNFGMRMINLAKCIASILVNNKTYYQ
GHAEYAFLLDYVPNWKFVYKPGAMIQYQVFIPKENAKQAFREIFTKCQDRGIVNYLSVFKKHKPDPFLLTHAVDGFSMAM
DFPVTKRNREKLWSLCYELDEIVLKHKGRFYFAKDSTLRKRVMESYFPKDNLKKFYTLKKKYDPKGILQTDLYKRVFLQS
V

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 55337; Mature: 55337

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKKTKSIPSIKVPHKEKVEAWGMSSFSMSPVFRPETEEEIKELFIWANQTGTKVALRG
CCCCCCCCCCCEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCEEEEEC
GGCSYGDASSNNDGIVLDLTRFNKVLDFNLKTGVMTVQSGARIKDLWETGIENGFWPPVV
CCCCCCCCCCCCCCEEEEEHHCCEEEEEECCCCEEEECCCCHHHHHHHHCCCCCCCCCCC
SGTMMPTLGGALSMNIHGKNNFKVGTIGEHIKEFTFLTAKGDILVCSPKKNSDLFYSAIS
CCCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHEEEEECCCEEEECCCCCCCHHHHHHH
GFGMLGCFLTVQIKMKPIYSGKMKIDPVYVRNFDELFEYFEEHYKTADYLVGWIDAFASG
HHHHEEEEEEEEEEEEEEECCCEEECEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KALGRGQIHKATNLKKGEDPDFPGNCLLERQHLPTRLFYLIPKKWMWILMRPFSFNFGMR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCHH
MINLAKCIASILVNNKTYYQGHAEYAFLLDYVPNWKFVYKPGAMIQYQVFIPKENAKQAF
HHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEEECCCCEEEEEEEECCCHHHHHH
REIFTKCQDRGIVNYLSVFKKHKPDPFLLTHAVDGFSMAMDFPVTKRNREKLWSLCYELD
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHH
EIVLKHKGRFYFAKDSTLRKRVMESYFPKDNLKKFYTLKKKYDPKGILQTDLYKRVFLQS
HHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
V
C
>Mature Secondary Structure
MVTKKTKSIPSIKVPHKEKVEAWGMSSFSMSPVFRPETEEEIKELFIWANQTGTKVALRG
CCCCCCCCCCCEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCEEEEEC
GGCSYGDASSNNDGIVLDLTRFNKVLDFNLKTGVMTVQSGARIKDLWETGIENGFWPPVV
CCCCCCCCCCCCCCEEEEEHHCCEEEEEECCCCEEEECCCCHHHHHHHHCCCCCCCCCCC
SGTMMPTLGGALSMNIHGKNNFKVGTIGEHIKEFTFLTAKGDILVCSPKKNSDLFYSAIS
CCCCCCCCCCEEEEEEECCCCEEEECHHHHHHHHEEEEECCCEEEECCCCCCCHHHHHHH
GFGMLGCFLTVQIKMKPIYSGKMKIDPVYVRNFDELFEYFEEHYKTADYLVGWIDAFASG
HHHHEEEEEEEEEEEEEEECCCEEECEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
KALGRGQIHKATNLKKGEDPDFPGNCLLERQHLPTRLFYLIPKKWMWILMRPFSFNFGMR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCHH
MINLAKCIASILVNNKTYYQGHAEYAFLLDYVPNWKFVYKPGAMIQYQVFIPKENAKQAF
HHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEEECCCCEEEEEEEECCCHHHHHH
REIFTKCQDRGIVNYLSVFKKHKPDPFLLTHAVDGFSMAMDFPVTKRNREKLWSLCYELD
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHH
EIVLKHKGRFYFAKDSTLRKRVMESYFPKDNLKKFYTLKKKYDPKGILQTDLYKRVFLQS
HHHHHCCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]