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The map label for this gene is resE [H]

Identifier: 183219921

GI number: 183219921

Start: 500308

End: 501822

Strand: Reverse

Name: resE [H]

Synonym: LEPBI_I0503

Alternate gene names: 183219921

Gene position: 501822-500308 (Counterclockwise)

Preceding gene: 183219929

Following gene: 183219920

Centisome position: 13.94

GC content: 38.22

Gene sequence:

>1515_bases
ATGAATGAATTTCTGGAAAAAATCAAAAGCTTTTTCAAGGATGAAGCGAGCTTTTTTGATGCAAAGCAACTTCTTGGCCA
AAATTGGCACAATTTTGTCCCACAATACTTTGACAAAATCCTAGAAACTCGTACGAATGCAGTGTATGTATTAGACAAGG
ATGGAAACTACACCTATGTCAACGCAAAAGCCGTCGAAATGGCGGGAAAATCCGCAGAAGAATTGTTAGGGCAAAATATT
TGGAATTTATTTCCTGTTTTACAAACAATTGAATTTGGAAACCAACTATCGGAAGCCATCAAAGAGAAAAAAACATTTCG
ATCAGAAGAAACCTACTTTGAAACTTTGGGTTGGTACGATATGCAAGTTTTCCCTCAGGAAAATTTTACCATCATCATTG
CAACAGAAGTCACACACACAAAAAATGCAAAAGATGAATATAGCCAAATCATCACCAAAAACAAAACCATTCTGAATGCT
TTACCTGATTTACTCTATGGAATCCATAGGAATGGTCAGGCCATCAATCACAAAGAATTCCCTCATTTCACAGGATGGGA
TTGTAAAAACAAAGAAACAAATCTTTGTTATTCTGACATAAAAGAAATTTTTCCGGAAAATAAATTAGAAGAAATCCAAA
CCATACTTCGGCAAGTGATTGATTTGGGTGTTAGCAAAGCAGTTGAATATTCGATCCACGACGCAGACGGTGAAAAATGT
TTCGAAGCAAGATTCACCAAAACGGGGGAAGTGGATGCACTTGCCATCATTCGGAATATCACAGAACGAAAAAAAGCAGA
GGCTTTAAAAAACGAATTCATCAGTTTGGTGAGTCATGAATTGCGAACCCCACTCACATCGATTAAAGGTTCCATTGATT
TACTGCTTGCGGGAGTGGCGGGAGAAGTATCCAACCAAACAAAATCCTTACTCAATATTTGTCGTAAAAATACACAAAGA
CTCGTTCGGTTTGTGACTGACCTTCTCGATATCGAAGCATTGGATTCTGGTAATATCAATTTTAAATTTAGAACCTACCA
ACTGAAAGAAATTCTACAAACTTCAGTGGATGGAATGCGCACGTTTGCAGAACAATATCATGTGCTTTTGAATTTTGATT
CTAATTTCCCACAAACAAGTGTTTATGTAGATGAAGACCGATTGAACCATTGTATCACCAATTTGATTTCCAATGCGGTG
AAATACACCCCCAAGTTTTCGGAAGTGACCATCTCTGTCCAAACAGATGCAACAAAGGCAAAAATCCAAATCAGGGATAA
TGGACCTGGCATTGATCCGAACTTTGCTCCAAGACTTTTCCACAGATTTGCCCAAGGGGCACCACCGAAGGACAAATTGG
TAGGTGGATCTGGGCTTGGACTTTCCATCACGAAAGGATTTGTCGAAGCCATGAATGGGAAAATTTACTTTTTTTCTGAT
GATTCGGGAACTGTTTTTACCATTGAACTACCAATTGTAATACCAGGACAAATTCCTGTTGGGATGAACCAATGA

Upstream 100 bases:

>100_bases
TTAAAATTGAGCCCTGAAATGGCTCGTTTTTCGCCGTAAAATTTGGATAAATTGCTGACTTGTATCATAACTTTGGTTTA
GTTTTCGTATACCTGCACCT

Downstream 100 bases:

>100_bases
GCATACAGGCCTTAAAACACGTGTTAATCGTGGAAGATGAAGAAGACATTGTCGAAATCCTTAGGATCGCACTTGCATTT
AACTCAAGTTATGAAGTGAG

Product: sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MNEFLEKIKSFFKDEASFFDAKQLLGQNWHNFVPQYFDKILETRTNAVYVLDKDGNYTYVNAKAVEMAGKSAEELLGQNI
WNLFPVLQTIEFGNQLSEAIKEKKTFRSEETYFETLGWYDMQVFPQENFTIIIATEVTHTKNAKDEYSQIITKNKTILNA
LPDLLYGIHRNGQAINHKEFPHFTGWDCKNKETNLCYSDIKEIFPENKLEEIQTILRQVIDLGVSKAVEYSIHDADGEKC
FEARFTKTGEVDALAIIRNITERKKAEALKNEFISLVSHELRTPLTSIKGSIDLLLAGVAGEVSNQTKSLLNICRKNTQR
LVRFVTDLLDIEALDSGNINFKFRTYQLKEILQTSVDGMRTFAEQYHVLLNFDSNFPQTSVYVDEDRLNHCITNLISNAV
KYTPKFSEVTISVQTDATKAKIQIRDNGPGIDPNFAPRLFHRFAQGAPPKDKLVGGSGLGLSITKGFVEAMNGKIYFFSD
DSGTVFTIELPIVIPGQIPVGMNQ

Sequences:

>Translated_504_residues
MNEFLEKIKSFFKDEASFFDAKQLLGQNWHNFVPQYFDKILETRTNAVYVLDKDGNYTYVNAKAVEMAGKSAEELLGQNI
WNLFPVLQTIEFGNQLSEAIKEKKTFRSEETYFETLGWYDMQVFPQENFTIIIATEVTHTKNAKDEYSQIITKNKTILNA
LPDLLYGIHRNGQAINHKEFPHFTGWDCKNKETNLCYSDIKEIFPENKLEEIQTILRQVIDLGVSKAVEYSIHDADGEKC
FEARFTKTGEVDALAIIRNITERKKAEALKNEFISLVSHELRTPLTSIKGSIDLLLAGVAGEVSNQTKSLLNICRKNTQR
LVRFVTDLLDIEALDSGNINFKFRTYQLKEILQTSVDGMRTFAEQYHVLLNFDSNFPQTSVYVDEDRLNHCITNLISNAV
KYTPKFSEVTISVQTDATKAKIQIRDNGPGIDPNFAPRLFHRFAQGAPPKDKLVGGSGLGLSITKGFVEAMNGKIYFFSD
DSGTVFTIELPIVIPGQIPVGMNQ
>Mature_504_residues
MNEFLEKIKSFFKDEASFFDAKQLLGQNWHNFVPQYFDKILETRTNAVYVLDKDGNYTYVNAKAVEMAGKSAEELLGQNI
WNLFPVLQTIEFGNQLSEAIKEKKTFRSEETYFETLGWYDMQVFPQENFTIIIATEVTHTKNAKDEYSQIITKNKTILNA
LPDLLYGIHRNGQAINHKEFPHFTGWDCKNKETNLCYSDIKEIFPENKLEEIQTILRQVIDLGVSKAVEYSIHDADGEKC
FEARFTKTGEVDALAIIRNITERKKAEALKNEFISLVSHELRTPLTSIKGSIDLLLAGVAGEVSNQTKSLLNICRKNTQR
LVRFVTDLLDIEALDSGNINFKFRTYQLKEILQTSVDGMRTFAEQYHVLLNFDSNFPQTSVYVDEDRLNHCITNLISNAV
KYTPKFSEVTISVQTDATKAKIQIRDNGPGIDPNFAPRLFHRFAQGAPPKDKLVGGSGLGLSITKGFVEAMNGKIYFFSD
DSGTVFTIELPIVIPGQIPVGMNQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=376, Percent_Identity=28.4574468085106, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=30.2127659574468, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081816, Length=319, Percent_Identity=27.8996865203762, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=27.5193798449612, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=33.7606837606838, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28.8888888888889, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI48994928, Length=365, Percent_Identity=26.5753424657534, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=26.8722466960352, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=221, Percent_Identity=25.3393665158371, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=27.7310924369748, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=272, Percent_Identity=27.2058823529412, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=24.2553191489362, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=24.7787610619469, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=286, Percent_Identity=23.4265734265734, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=25.609756097561, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57187; Mature: 57187

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFLEKIKSFFKDEASFFDAKQLLGQNWHNFVPQYFDKILETRTNAVYVLDKDGNYTYV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEE
NAKAVEMAGKSAEELLGQNIWNLFPVLQTIEFGNQLSEAIKEKKTFRSEETYFETLGWYD
ECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEE
MQVFPQENFTIIIATEVTHTKNAKDEYSQIITKNKTILNALPDLLYGIHRNGQAINHKEF
EEEECCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PHFTGWDCKNKETNLCYSDIKEIFPENKLEEIQTILRQVIDLGVSKAVEYSIHDADGEKC
CCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHEEEEECCCCHHH
FEARFTKTGEVDALAIIRNITERKKAEALKNEFISLVSHELRTPLTSIKGSIDLLLAGVA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEHHH
GEVSNQTKSLLNICRKNTQRLVRFVTDLLDIEALDSGNINFKFRTYQLKEILQTSVDGMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHH
TFAEQYHVLLNFDSNFPQTSVYVDEDRLNHCITNLISNAVKYTPKFSEVTISVQTDATKA
HHHHHCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEE
KIQIRDNGPGIDPNFAPRLFHRFAQGAPPKDKLVGGSGLGLSITKGFVEAMNGKIYFFSD
EEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEC
DSGTVFTIELPIVIPGQIPVGMNQ
CCCEEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNEFLEKIKSFFKDEASFFDAKQLLGQNWHNFVPQYFDKILETRTNAVYVLDKDGNYTYV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEE
NAKAVEMAGKSAEELLGQNIWNLFPVLQTIEFGNQLSEAIKEKKTFRSEETYFETLGWYD
ECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEE
MQVFPQENFTIIIATEVTHTKNAKDEYSQIITKNKTILNALPDLLYGIHRNGQAINHKEF
EEEECCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PHFTGWDCKNKETNLCYSDIKEIFPENKLEEIQTILRQVIDLGVSKAVEYSIHDADGEKC
CCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHEEEEECCCCHHH
FEARFTKTGEVDALAIIRNITERKKAEALKNEFISLVSHELRTPLTSIKGSIDLLLAGVA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHEEEHHH
GEVSNQTKSLLNICRKNTQRLVRFVTDLLDIEALDSGNINFKFRTYQLKEILQTSVDGMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHH
TFAEQYHVLLNFDSNFPQTSVYVDEDRLNHCITNLISNAVKYTPKFSEVTISVQTDATKA
HHHHHCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEE
KIQIRDNGPGIDPNFAPRLFHRFAQGAPPKDKLVGGSGLGLSITKGFVEAMNGKIYFFSD
EEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEC
DSGTVFTIELPIVIPGQIPVGMNQ
CCCEEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]