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The map label for this gene is sglT [H]

Identifier: 183219667

GI number: 183219667

Start: 232411

End: 234003

Strand: Direct

Name: sglT [H]

Synonym: LEPBI_I0242

Alternate gene names: 183219667

Gene position: 232411-234003 (Clockwise)

Preceding gene: 183219656

Following gene: 183219668

Centisome position: 6.46

GC content: 40.55

Gene sequence:

>1593_bases
ATGTTTGTTGCTCTAAGCCCTATCGATACCCTCATTGTCTTCGTTTTTGTTGGTTTTATGGTGGTGATTGGGGTGCTTTT
GAAAAAATCCATGAACCATTCCACGGATTTTTTACTCGCAGGAAGGAAAATCCCCAGTTGGATCACGGGCATTGCCTTCA
TTTCGGCCAATATCTCCGCCTTAGAATTGTTAGGGATGAGTGCCAGTGGGGCAGAGTATGGCTTTTTGACGTTTCATTTT
TATTACTTAGGTGCGATCCCTGGAATGATTTTTCTTGGGATCTTTATGATGCCGTTTTATTACTCTACAAAGATACGAAG
TGTCCCTGAATACCTGAGGTATCGTTTCAATCGAGAGGCGCACTTAGTCAATTCGCTCATCACCTTGTTGTCCCTAGCCC
TTGGGTCAGGGATCTACTTGTATTCTTTGTCCTTAGTGTTTGAAACTTTATTTGGTTGGAACCCACACCTTTCCATTCTA
TTCAGCGCTCTCATTGTTTTGATTTATACTTATTTTGGGGGACTCAGTTCTTCCATTTATACAGAAGTGATGCAGTTTTT
TCTGACTGTCATTGGACTTTTCCCATTGGTCATTATCGGTTTAACAAAGTTAGGTGGATGGGATGGTCTGATGCAAAAAA
TCCCCGAGTCACACAAACATATGTGGGTGGGACTTCCTGGAGGACAAAATGAACTGGGTTGGGATGTCTTAAGTGTCACC
GTTGGACTTGGTTTTGTTTTGTCTTTTTCCTATTGGACCTGTGGGTTTGCGGAAGTGCAAAGGGCAATGGCTGCAAAAGA
TTTTCGTGCGGCACGAAGGACACCTCTTATCGGAGCCATGTTCAAATTATTTTTACCGTTTCTCACAGTGATCCCTGGAC
TCATCGCACTTGCCGAATATTCCACAGAAATGAATGGAGAGTATAACAAAAGTTTTCTCATCTTACTCAAGAACTTTTAT
CCATCGGGGATGTTAGGGCTTGGAACGTCGGCACTGCTTGCTGCCTTTATGGCGGGGATGTCAAGTTCTGTCACAGCGAT
GAATACTATTTTTACTTATGATATTTACCAAACTTATATCAATAAAGATAAAGATGACAAAACCTATTTAAGAATTGGAA
AACAAAGTACGATGGTTGCCGTTATATTTGCCATCTTTACCTCTTATATAGCGATGCAATTTGAAAACATCATGAATTAC
ATCCAGTTACTGTTTTCGTTTTTTAATGCCCCACTCATCTCAATTTTTTTACTTGGTATGTTTTGGAAAAAAGCATCCAA
ATGGAGTGCCTTCTACGGGATGTTAGTGGGGACGGCCAGTGGCCTAATACACTATTTTTTATATGCCAATGGTTATTTGT
ATTACAAATCAGATATGGTATCCAATTTTTATGGTGCCATTTATTCAGGAGTGTTTTGTTTTTTAGTGATGGTGGTTGTG
AGTCTTTGGGAATCAGAAGATCCAAATCGAGACTTACATGGGTTAGTGTATGAAGACAGAGATCGAACCAATGAATTTTG
GGACCCTAGGATCCTTGCCTGGGGAGTGATTCTCATTGTCCTTCTTGCAGGGTTTAATATCGTTTTTGCGTAA

Upstream 100 bases:

>100_bases
TCGGCGGGTTTGGAATTTTTTTTAGGAAAATATTCCCAAGATCCACCCCTTCGGGATTTCCACTTTACAATCTCCAATTC
TCGGTTTCCCTTACAAACCT

Downstream 100 bases:

>100_bases
AGATTTATACAACCGTAACAAAATAGTAATTGAAGGAGAGTATTCTTCTTCCTATGTTTGTTGCAGTATACACAAAGACT
ATGAAACCAAATCATTATAC

Product: putative sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MFVALSPIDTLIVFVFVGFMVVIGVLLKKSMNHSTDFLLAGRKIPSWITGIAFISANISALELLGMSASGAEYGFLTFHF
YYLGAIPGMIFLGIFMMPFYYSTKIRSVPEYLRYRFNREAHLVNSLITLLSLALGSGIYLYSLSLVFETLFGWNPHLSIL
FSALIVLIYTYFGGLSSSIYTEVMQFFLTVIGLFPLVIIGLTKLGGWDGLMQKIPESHKHMWVGLPGGQNELGWDVLSVT
VGLGFVLSFSYWTCGFAEVQRAMAAKDFRAARRTPLIGAMFKLFLPFLTVIPGLIALAEYSTEMNGEYNKSFLILLKNFY
PSGMLGLGTSALLAAFMAGMSSSVTAMNTIFTYDIYQTYINKDKDDKTYLRIGKQSTMVAVIFAIFTSYIAMQFENIMNY
IQLLFSFFNAPLISIFLLGMFWKKASKWSAFYGMLVGTASGLIHYFLYANGYLYYKSDMVSNFYGAIYSGVFCFLVMVVV
SLWESEDPNRDLHGLVYEDRDRTNEFWDPRILAWGVILIVLLAGFNIVFA

Sequences:

>Translated_530_residues
MFVALSPIDTLIVFVFVGFMVVIGVLLKKSMNHSTDFLLAGRKIPSWITGIAFISANISALELLGMSASGAEYGFLTFHF
YYLGAIPGMIFLGIFMMPFYYSTKIRSVPEYLRYRFNREAHLVNSLITLLSLALGSGIYLYSLSLVFETLFGWNPHLSIL
FSALIVLIYTYFGGLSSSIYTEVMQFFLTVIGLFPLVIIGLTKLGGWDGLMQKIPESHKHMWVGLPGGQNELGWDVLSVT
VGLGFVLSFSYWTCGFAEVQRAMAAKDFRAARRTPLIGAMFKLFLPFLTVIPGLIALAEYSTEMNGEYNKSFLILLKNFY
PSGMLGLGTSALLAAFMAGMSSSVTAMNTIFTYDIYQTYINKDKDDKTYLRIGKQSTMVAVIFAIFTSYIAMQFENIMNY
IQLLFSFFNAPLISIFLLGMFWKKASKWSAFYGMLVGTASGLIHYFLYANGYLYYKSDMVSNFYGAIYSGVFCFLVMVVV
SLWESEDPNRDLHGLVYEDRDRTNEFWDPRILAWGVILIVLLAGFNIVFA
>Mature_530_residues
MFVALSPIDTLIVFVFVGFMVVIGVLLKKSMNHSTDFLLAGRKIPSWITGIAFISANISALELLGMSASGAEYGFLTFHF
YYLGAIPGMIFLGIFMMPFYYSTKIRSVPEYLRYRFNREAHLVNSLITLLSLALGSGIYLYSLSLVFETLFGWNPHLSIL
FSALIVLIYTYFGGLSSSIYTEVMQFFLTVIGLFPLVIIGLTKLGGWDGLMQKIPESHKHMWVGLPGGQNELGWDVLSVT
VGLGFVLSFSYWTCGFAEVQRAMAAKDFRAARRTPLIGAMFKLFLPFLTVIPGLIALAEYSTEMNGEYNKSFLILLKNFY
PSGMLGLGTSALLAAFMAGMSSSVTAMNTIFTYDIYQTYINKDKDDKTYLRIGKQSTMVAVIFAIFTSYIAMQFENIMNY
IQLLFSFFNAPLISIFLLGMFWKKASKWSAFYGMLVGTASGLIHYFLYANGYLYYKSDMVSNFYGAIYSGVFCFLVMVVV
SLWESEDPNRDLHGLVYEDRDRTNEFWDPRILAWGVILIVLLAGFNIVFA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI110835708, Length=576, Percent_Identity=26.2152777777778, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI14140236, Length=552, Percent_Identity=24.8188405797101, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI4507033, Length=564, Percent_Identity=26.063829787234, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI4507031, Length=565, Percent_Identity=25.1327433628319, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI206597483, Length=520, Percent_Identity=24.8076923076923, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI206597487, Length=458, Percent_Identity=24.8908296943231, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI17941285, Length=464, Percent_Identity=23.4913793103448, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI109659836, Length=480, Percent_Identity=25.4166666666667, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI109659839, Length=496, Percent_Identity=24.7983870967742, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI256985183, Length=430, Percent_Identity=22.5581395348837, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI167466278, Length=446, Percent_Identity=21.9730941704036, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4507035, Length=430, Percent_Identity=22.093023255814, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI157671931, Length=427, Percent_Identity=20.3747072599532, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI310128183, Length=432, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790113, Length=455, Percent_Identity=23.5164835164835, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787251, Length=449, Percent_Identity=19.8218262806236, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790503, Length=448, Percent_Identity=22.5446428571429, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566512, Length=361, Percent_Identity=21.8836565096953, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533094, Length=494, Percent_Identity=19.8380566801619, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573698, Length=443, Percent_Identity=23.9277652370203, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651739, Length=471, Percent_Identity=21.2314225053079, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281362918, Length=455, Percent_Identity=20.8791208791209, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24651741, Length=436, Percent_Identity=20.1834862385321, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24645928, Length=462, Percent_Identity=22.9437229437229, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221459586, Length=423, Percent_Identity=21.0401891252955, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221459588, Length=427, Percent_Identity=22.0140515222482, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641117, Length=449, Percent_Identity=22.71714922049, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24650192, Length=348, Percent_Identity=22.1264367816092, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221459582, Length=421, Percent_Identity=23.0403800475059, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221459584, Length=415, Percent_Identity=21.2048192771084, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640370, Length=431, Percent_Identity=25.754060324826, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281362054, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362052, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362050, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648056, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356827, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59612; Mature: 59612

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure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HHHCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]