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The map label for this gene is sanA [H]

Identifier: 183219644

GI number: 183219644

Start: 210311

End: 211048

Strand: Direct

Name: sanA [H]

Synonym: LEPBI_I0219

Alternate gene names: 183219644

Gene position: 210311-211048 (Clockwise)

Preceding gene: 183219640

Following gene: 183219645

Centisome position: 5.84

GC content: 41.6

Gene sequence:

>738_bases
ATGACGAACCGCGATTCCTACATAAATAAGACGCTCCGATTCCTTTCCAGGGTCAAGTGGAAATCCCTGTTTCTGGGTTT
CATACTGGTTTTTGGAATTCTTGGTTTTGTCTCATTGGCTTCCAATTTAGGATTTTGGATTGTCTACCAGAACTCCATTC
ACACAAACAATCCCTCGGAAATCCCTGAAGCAGAAGTGGCGATCGTTCCAGGAGCCGCTGTGTATGGAAAAATTCCTTCT
CCCATCCTCATGGACCGACTGGTCTGTGGATTGGATTTGTACAAACAAGGTAAGGTCAAAAAGATTTTACTATCAGGTGA
TAACGGAAAGTCGGATTACAACGAATTAAGGCCAATGTTGGAATACATGTTGTCCCATGAAGTCAGACCAGAAGATATAT
TTGTAGACCATGCTGGATTTCGGACGCTTGATACTTTGATCCGAGCCAAAGAAGTGTTTTTGGTGAAAAAGGCAATTTTT
GTAAGCCAATCCTTCTTTTTACCACGAGCGATTTATTTAGGTAAAGAACTAGAACTCGAGTTATACGGTTACGAGTGTAA
TTTGCGAACGTATAAAAAAGAAACTTATTATTTGTTTCGTGAATTTTCTGCACGTATGCTCGCTTGGTGGGACATTCAAT
GGGACACTCCACCCAAATACTTGGGTGAACCGTATCCAATCGAGGGAAGTGGGATCAGTACTTGGAAAGGATCTATTCCC
GTATCAATTCCCAAATGA

Upstream 100 bases:

>100_bases
CATCCGTTGGTGACCTTTTTCTTTCACCTTATCAATCTGTTTCTTGATTTTCGGATTGTCTTGTGAAAAAACAGACGTAA
TCTCTTTAATTTTTTTCTTC

Downstream 100 bases:

>100_bases
CTGTTTCTAGAAAACATAATCTCCTTTCGATTCAAACGATGATTGTTAGTTTTGTTTCCATTGGAATCTTTTCTTGGATA
CCCAAACAATTGTTCTCCTC

Product: putative vancomycin sensitivity protein SanA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTNRDSYINKTLRFLSRVKWKSLFLGFILVFGILGFVSLASNLGFWIVYQNSIHTNNPSEIPEAEVAIVPGAAVYGKIPS
PILMDRLVCGLDLYKQGKVKKILLSGDNGKSDYNELRPMLEYMLSHEVRPEDIFVDHAGFRTLDTLIRAKEVFLVKKAIF
VSQSFFLPRAIYLGKELELELYGYECNLRTYKKETYYLFREFSARMLAWWDIQWDTPPKYLGEPYPIEGSGISTWKGSIP
VSIPK

Sequences:

>Translated_245_residues
MTNRDSYINKTLRFLSRVKWKSLFLGFILVFGILGFVSLASNLGFWIVYQNSIHTNNPSEIPEAEVAIVPGAAVYGKIPS
PILMDRLVCGLDLYKQGKVKKILLSGDNGKSDYNELRPMLEYMLSHEVRPEDIFVDHAGFRTLDTLIRAKEVFLVKKAIF
VSQSFFLPRAIYLGKELELELYGYECNLRTYKKETYYLFREFSARMLAWWDIQWDTPPKYLGEPYPIEGSGISTWKGSIP
VSIPK
>Mature_244_residues
TNRDSYINKTLRFLSRVKWKSLFLGFILVFGILGFVSLASNLGFWIVYQNSIHTNNPSEIPEAEVAIVPGAAVYGKIPSP
ILMDRLVCGLDLYKQGKVKKILLSGDNGKSDYNELRPMLEYMLSHEVRPEDIFVDHAGFRTLDTLIRAKEVFLVKKAIFV
SQSFFLPRAIYLGKELELELYGYECNLRTYKKETYYLFREFSARMLAWWDIQWDTPPKYLGEPYPIEGSGISTWKGSIPV
SIPK

Specific function: Participates in the barrier function of the cell envelope [H]

COG id: COG2949

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789468, Length=184, Percent_Identity=33.695652173913, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788466, Length=172, Percent_Identity=31.9767441860465, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003848
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02698 DUF218 [H]

EC number: NA

Molecular weight: Translated: 28199; Mature: 28068

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRDSYINKTLRFLSRVKWKSLFLGFILVFGILGFVSLASNLGFWIVYQNSIHTNNPSE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
IPEAEVAIVPGAAVYGKIPSPILMDRLVCGLDLYKQGKVKKILLSGDNGKSDYNELRPML
CCCCEEEEECCHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EYMLSHEVRPEDIFVDHAGFRTLDTLIRAKEVFLVKKAIFVSQSFFLPRAIYLGKELELE
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LYGYECNLRTYKKETYYLFREFSARMLAWWDIQWDTPPKYLGEPYPIEGSGISTWKGSIP
EEEEEECCEEEHHHHHHHHHHHCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCEECCCCC
VSIPK
EECCC
>Mature Secondary Structure 
TNRDSYINKTLRFLSRVKWKSLFLGFILVFGILGFVSLASNLGFWIVYQNSIHTNNPSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
IPEAEVAIVPGAAVYGKIPSPILMDRLVCGLDLYKQGKVKKILLSGDNGKSDYNELRPML
CCCCEEEEECCHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHH
EYMLSHEVRPEDIFVDHAGFRTLDTLIRAKEVFLVKKAIFVSQSFFLPRAIYLGKELELE
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LYGYECNLRTYKKETYYLFREFSARMLAWWDIQWDTPPKYLGEPYPIEGSGISTWKGSIP
EEEEEECCEEEHHHHHHHHHHHCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCEECCCCC
VSIPK
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]