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The map label for this gene is queC

Identifier: 183219600

GI number: 183219600

Start: 169911

End: 170657

Strand: Direct

Name: queC

Synonym: LEPBI_I0175

Alternate gene names: 183219600

Gene position: 169911-170657 (Clockwise)

Preceding gene: 183219599

Following gene: 183219601

Centisome position: 4.72

GC content: 38.55

Gene sequence:

>747_bases
ATGGTTTCCATTCTGGATTCCTCTTTCAAATCTAAAACTGAAAAGAAAGGTGCCATCGTACTTCTGTCAGGTGGACTTGA
TTCAACGACTTGTTTGTATTTGGCTGCCAAGGATTTTGGATATCCTAAAAATAAAAAATTACCACTCCTAGCTCTTTCCT
TTGATTATTCTCAAAAACATAAAATAGAGCTGACCAAAAGTAAAAAAATCGCAAAAACCCTTGGGATCAAACATGTGATC
CAAAAATTGGATCCAGGATTTTTTTTAGGAAGTTCTCTCACTGAATCAAAAATTAAGGTAAGGAAAAACGCCAAATCACT
ATTTAGTGGTGATGAAACAGAAATTCCGAATACCTATGTTCCTGGACGTAACATTCTCTTTTTATCTTTTGCTTTATCAC
TCGCAGAAGGGCATGGGTATGATTCGATTTATATTGGAGTGAATGCACTCGATTATTCAGGTTATCCTGATTGTAGACCT
GAGTTCATTGATTCCTTCCAAAAGATGGCAAACCTTGGGACGAAAAAAGGGGTGAGTGGGACAGGGGATTCGATCCAGAT
CAAAACACCTCTCCTTCATTTGGGTAAAAAAGAAATCATCGAACTAGGAATGTCAGTCGGAGCTCCTCTAGGACTCACAC
ATTCTTGTTATGATCCTGTGAGTGGAAAACCATGCGGCAAATGTGATTCTTGTATTTTACGGGCCAAAGGATTTTTGGAA
GTTGGTTTGAAAGATCCGGCGTTGTGA

Upstream 100 bases:

>100_bases
GCTTTGGAACCAACTGAAACCAAAACTTCCCTTACTCGATAAAATCACATTGTATGAAACTTGCACGAGTTCTTGTGTGT
ACAGGGGTCCAAAAAAGTAA

Downstream 100 bases:

>100_bases
AGGATAAAAATACGAAATGCGCAAATTGGTTCTCCTCATCCTCTTATTACCATTTGTACAATGCGATAAAACCAAAACAT
CGAATGATATGTTTCTCATT

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MVSILDSSFKSKTEKKGAIVLLSGGLDSTTCLYLAAKDFGYPKNKKLPLLALSFDYSQKHKIELTKSKKIAKTLGIKHVI
QKLDPGFFLGSSLTESKIKVRKNAKSLFSGDETEIPNTYVPGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRP
EFIDSFQKMANLGTKKGVSGTGDSIQIKTPLLHLGKKEIIELGMSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLE
VGLKDPAL

Sequences:

>Translated_248_residues
MVSILDSSFKSKTEKKGAIVLLSGGLDSTTCLYLAAKDFGYPKNKKLPLLALSFDYSQKHKIELTKSKKIAKTLGIKHVI
QKLDPGFFLGSSLTESKIKVRKNAKSLFSGDETEIPNTYVPGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRP
EFIDSFQKMANLGTKKGVSGTGDSIQIKTPLLHLGKKEIIELGMSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLE
VGLKDPAL
>Mature_248_residues
MVSILDSSFKSKTEKKGAIVLLSGGLDSTTCLYLAAKDFGYPKNKKLPLLALSFDYSQKHKIELTKSKKIAKTLGIKHVI
QKLDPGFFLGSSLTESKIKVRKNAKSLFSGDETEIPNTYVPGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRP
EFIDSFQKMANLGTKKGVSGTGDSIQIKTPLLHLGKKEIIELGMSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLE
VGLKDPAL

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=229, Percent_Identity=35.3711790393013, Blast_Score=123, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_LEPBA (B0S9S9)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961294.1
- ProteinModelPortal:   B0S9S9
- SMR:   B0S9S9
- GeneID:   6389407
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0170
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK573455
- BioCyc:   LBIF355278:LBF_0170-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26816; Mature: 26816

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSILDSSFKSKTEKKGAIVLLSGGLDSTTCLYLAAKDFGYPKNKKLPLLALSFDYSQKH
CCCCCCCHHHHHHCCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCEEEEEECCCCCCE
KIELTKSKKIAKTLGIKHVIQKLDPGFFLGSSLTESKIKVRKNAKSLFSGDETEIPNTYV
EEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRPEFIDSFQKMANLGTKKGVSG
CCCCEEHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TGDSIQIKTPLLHLGKKEIIELGMSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLE
CCCEEEEECHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
VGLKDPAL
ECCCCCCC
>Mature Secondary Structure
MVSILDSSFKSKTEKKGAIVLLSGGLDSTTCLYLAAKDFGYPKNKKLPLLALSFDYSQKH
CCCCCCCHHHHHHCCCCEEEEEECCCCCCEEEEEEEHHCCCCCCCCCEEEEEECCCCCCE
KIELTKSKKIAKTLGIKHVIQKLDPGFFLGSSLTESKIKVRKNAKSLFSGDETEIPNTYV
EEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRPEFIDSFQKMANLGTKKGVSG
CCCCEEHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TGDSIQIKTPLLHLGKKEIIELGMSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLE
CCCEEEEECHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
VGLKDPAL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA