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The map label for this gene is estA [H]

Identifier: 183219471

GI number: 183219471

Start: 43771

End: 44421

Strand: Direct

Name: estA [H]

Synonym: LEPBI_I0044

Alternate gene names: 183219471

Gene position: 43771-44421 (Clockwise)

Preceding gene: 183219470

Following gene: 183219473

Centisome position: 1.22

GC content: 38.25

Gene sequence:

>651_bases
ATGAATCCACCATTAACTTACTTAATCCGAAAGCCAAAAGTTTCGATCAAAAATCCTCCACTACTTCTTTTGTTACACGG
TGTGGGTAGCAATGAAAAAGATTTATTTTCCCTAACAGATGATTTACCAGATCCCCTTCTCATTGTTTCCCTTCGAGGAC
CCATCACTCTTGGTCGGGATCGATTCGGTTGGTATGAGATCTCATTCACTGGAGGAACTCCTAAGATCAATGCCGACCAA
CAGATGAAGAGTCAAAAAATATTAATCGATTTTTTGAATTATCTACAAACAAAATACCAATTTGATGCCAATCGTGTTTG
GATTGGTGGTTTTAGCCAAGGGGCAGTGATGTCTTATTCAGTCGGTTTATTACATCCAGACCAATTTACTGGAATCATTG
CGCTCAGTGGACGTCTGTTAGAGGAAACAAAACATCAATTTCAAATAGAAAGTTCTTCCAACTTTCCAAAAGTTTACATC
GCCCACGGAACAAACGACAATGTGATCGCTGTTTCAAAAGCAAGAGACTCGAAAGAATTTTTAGAGTCGGTAGGAATCAT
TCCTCATTACAAAGAATATTCGGAAGGGCATACGATTAGTGCAGAAATGTTGAAAGATTTGATAGTTTGGTTGGAAAAGG
AAATGGAATAA

Upstream 100 bases:

>100_bases
GCTGGAGCATTGACGATGACTTCCGTACGTTTGGACTCTGACTTACATGAATCATAATTGTCGCTATAAATCTCCATATA
AAGGTATCTAACGAATTTTT

Downstream 100 bases:

>100_bases
AAAAAGTTTTTGTTATGTGACGAATCCCATTCTCAATAATAGTTGAAAGGATACTTTTCTCTCTTTTTGATTTTCGAAAA
ACGGTTTCATTAACGATTGA

Product: putative carboxylesterase 2

Products: NA

Alternate protein names: Esterase I [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNPPLTYLIRKPKVSIKNPPLLLLLHGVGSNEKDLFSLTDDLPDPLLIVSLRGPITLGRDRFGWYEISFTGGTPKINADQ
QMKSQKILIDFLNYLQTKYQFDANRVWIGGFSQGAVMSYSVGLLHPDQFTGIIALSGRLLEETKHQFQIESSSNFPKVYI
AHGTNDNVIAVSKARDSKEFLESVGIIPHYKEYSEGHTISAEMLKDLIVWLEKEME

Sequences:

>Translated_216_residues
MNPPLTYLIRKPKVSIKNPPLLLLLHGVGSNEKDLFSLTDDLPDPLLIVSLRGPITLGRDRFGWYEISFTGGTPKINADQ
QMKSQKILIDFLNYLQTKYQFDANRVWIGGFSQGAVMSYSVGLLHPDQFTGIIALSGRLLEETKHQFQIESSSNFPKVYI
AHGTNDNVIAVSKARDSKEFLESVGIIPHYKEYSEGHTISAEMLKDLIVWLEKEME
>Mature_216_residues
MNPPLTYLIRKPKVSIKNPPLLLLLHGVGSNEKDLFSLTDDLPDPLLIVSLRGPITLGRDRFGWYEISFTGGTPKINADQ
QMKSQKILIDFLNYLQTKYQFDANRVWIGGFSQGAVMSYSVGLLHPDQFTGIIALSGRLLEETKHQFQIESSSNFPKVYI
AHGTNDNVIAVSKARDSKEFLESVGIIPHYKEYSEGHTISAEMLKDLIVWLEKEME

Specific function: Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity [H]

COG id: COG0400

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003140 [H]

Pfam domain/function: PF02230 Abhydrolase_2 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 24383; Mature: 24383

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPLTYLIRKPKVSIKNPPLLLLLHGVGSNEKDLFSLTDDLPDPLLIVSLRGPITLGRD
CCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEHHCCCCCCEEEEEECCCEEECCC
RFGWYEISFTGGTPKINADQQMKSQKILIDFLNYLQTKYQFDANRVWIGGFSQGAVMSYS
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEEE
VGLLHPDQFTGIIALSGRLLEETKHQFQIESSSNFPKVYIAHGTNDNVIAVSKARDSKEF
EEEECCCHHCEEEEECCHHHHHHHHEEEEECCCCCCEEEEEECCCCCEEEEECCCCHHHH
LESVGIIPHYKEYSEGHTISAEMLKDLIVWLEKEME
HHHCCCCCCCHHHCCCCEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPPLTYLIRKPKVSIKNPPLLLLLHGVGSNEKDLFSLTDDLPDPLLIVSLRGPITLGRD
CCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEHHCCCCCCEEEEEECCCEEECCC
RFGWYEISFTGGTPKINADQQMKSQKILIDFLNYLQTKYQFDANRVWIGGFSQGAVMSYS
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEEE
VGLLHPDQFTGIIALSGRLLEETKHQFQIESSSNFPKVYIAHGTNDNVIAVSKARDSKEF
EEEECCCHHCEEEEECCHHHHHHHHEEEEECCCCCCEEEEEECCCCCEEEEECCCCHHHH
LESVGIIPHYKEYSEGHTISAEMLKDLIVWLEKEME
HHHCCCCCCCHHHCCCCEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA