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The map label for this gene is ywlC [H]

Identifier: 18311182

GI number: 18311182

Start: 2519346

End: 2520398

Strand: Reverse

Name: ywlC [H]

Synonym: CPE2200

Alternate gene names: 18311182

Gene position: 2520398-2519346 (Counterclockwise)

Preceding gene: 18311183

Following gene: 18311181

Centisome position: 83.14

GC content: 31.15

Gene sequence:

>1053_bases
ATGAAAACAAAAGTACAATTCATAAAAGATATAGATAAAGATATAAAATATTTAGAGGAAGCCGCTGAAATAATAAAAAA
TGGTGGTATTGGGGCATTTCCTACTGAAACAGTTTATGGATTAGGCGCAAATGCTTTAGATGGAGAAGCTGTTAAAAAGA
TTTTTGTGGCAAAGGGAAGACCCCAGGATAATCCTTTAATAATACATATAGCTGATAAAAAAGATATAGATAAATATGTT
GCTGAAATACCTAAATATGCACAGGAGTTAATGGATAAATTTTGGCCAGGTCCTTTAACGATAATATTAAAGAAAAAAGA
TATAGTTTCAGATGTTACATCAGCAGGTTTAGATACAGTTGGAGTTAGAATGCCAAATGATGAAATAGCCTTAAAGCTAA
TAGAACTATCAGGAGTTCCAATAGCAGCACCATCAGCTAATATATCAGGAAGACCAAGTCCTACAGATATAGAAAGATGT
GAAGAAGACTTAAATGGAAGAGTTGATTTTATAATAGGAGCTAAAAAAAGTGAAATAGGAGTAGAATCAACTATAGTAGA
TGCAACAGGTGAACATTTATGCGTTTTAAGACCTGGAGGCATAACTTTAGAGATGTTAAAGGACATAGATGAAGGGGTAG
ATATAGATAAAGCTATATTAACTACTTTAGATAAAGATACAAAACCTAAGGCACCTGGAATGAAGTATAAACATTATGCA
CCAAAGGCAAAAGTTAGAATGGTTCAAGGTCCAATAAATAAAATGGTTGAAAAAATTAAAGAAATAGTGCATAATTACAT
AGATGAAGATTTAAAAGTCGGAATTATGGCAACTGATGAAACAATTTCTATGTATGATGAAGGAATAGTAAAATCATTAG
GAACTAGAGAAGACTTAACTTCTGTAACAAAAAATTTATTTGAAATGCTTAGAGCTTTTGATGACTTAGGGGTAGATGTT
ATAATAACTGAGGCTTTTGAGGAAAAAGATTTAGGTGTAGCCATAATGAATAGATTAAAAAAATCCTGTGGATTTGACAT
AACAATAGTTTAA

Upstream 100 bases:

>100_bases
AAAAATTGTGTTACAGCAACTTATACAAATGATAGTATTGAAAATATAAAGATCGCAAGAGGTCAGAAGAATTTATAAAA
GATGAAGGTGATATTGTTTT

Downstream 100 bases:

>100_bases
GAATATATATGGAAGGAGCTAGATAAAAATGAAACTTTTGAGAAAAAGGAACTGTTTTGAATTTATATTTTTTAAAAATT
CTATATTTGTTTTTTTTGAA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKTKVQFIKDIDKDIKYLEEAAEIIKNGGIGAFPTETVYGLGANALDGEAVKKIFVAKGRPQDNPLIIHIADKKDIDKYV
AEIPKYAQELMDKFWPGPLTIILKKKDIVSDVTSAGLDTVGVRMPNDEIALKLIELSGVPIAAPSANISGRPSPTDIERC
EEDLNGRVDFIIGAKKSEIGVESTIVDATGEHLCVLRPGGITLEMLKDIDEGVDIDKAILTTLDKDTKPKAPGMKYKHYA
PKAKVRMVQGPINKMVEKIKEIVHNYIDEDLKVGIMATDETISMYDEGIVKSLGTREDLTSVTKNLFEMLRAFDDLGVDV
IITEAFEEKDLGVAIMNRLKKSCGFDITIV

Sequences:

>Translated_350_residues
MKTKVQFIKDIDKDIKYLEEAAEIIKNGGIGAFPTETVYGLGANALDGEAVKKIFVAKGRPQDNPLIIHIADKKDIDKYV
AEIPKYAQELMDKFWPGPLTIILKKKDIVSDVTSAGLDTVGVRMPNDEIALKLIELSGVPIAAPSANISGRPSPTDIERC
EEDLNGRVDFIIGAKKSEIGVESTIVDATGEHLCVLRPGGITLEMLKDIDEGVDIDKAILTTLDKDTKPKAPGMKYKHYA
PKAKVRMVQGPINKMVEKIKEIVHNYIDEDLKVGIMATDETISMYDEGIVKSLGTREDLTSVTKNLFEMLRAFDDLGVDV
IITEAFEEKDLGVAIMNRLKKSCGFDITIV
>Mature_350_residues
MKTKVQFIKDIDKDIKYLEEAAEIIKNGGIGAFPTETVYGLGANALDGEAVKKIFVAKGRPQDNPLIIHIADKKDIDKYV
AEIPKYAQELMDKFWPGPLTIILKKKDIVSDVTSAGLDTVGVRMPNDEIALKLIELSGVPIAAPSANISGRPSPTDIERC
EEDLNGRVDFIIGAKKSEIGVESTIVDATGEHLCVLRPGGITLEMLKDIDEGVDIDKAILTTLDKDTKPKAPGMKYKHYA
PKAKVRMVQGPINKMVEKIKEIVHNYIDEDLKVGIMATDETISMYDEGIVKSLGTREDLTSVTKNLFEMLRAFDDLGVDV
IITEAFEEKDLGVAIMNRLKKSCGFDITIV

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI87081864, Length=196, Percent_Identity=27.0408163265306, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367210, Length=174, Percent_Identity=25.2873563218391, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=176, Percent_Identity=30.1136363636364, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=371, Percent_Identity=35.0404312668464, Blast_Score=192, Evalue=5e-50,
Organism=Drosophila melanogaster, GI78707274, Length=142, Percent_Identity=27.4647887323944, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38490; Mature: 38490

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKVQFIKDIDKDIKYLEEAAEIIKNGGIGAFPTETVYGLGANALDGEAVKKIFVAKGR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCC
PQDNPLIIHIADKKDIDKYVAEIPKYAQELMDKFWPGPLTIILKKKDIVSDVTSAGLDTV
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCE
GVRMPNDEIALKLIELSGVPIAAPSANISGRPSPTDIERCEEDLNGRVDFIIGAKKSEIG
EEECCCHHHEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCC
VESTIVDATGEHLCVLRPGGITLEMLKDIDEGVDIDKAILTTLDKDTKPKAPGMKYKHYA
CHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PKAKVRMVQGPINKMVEKIKEIVHNYIDEDLKVGIMATDETISMYDEGIVKSLGTREDLT
CCHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHH
SVTKNLFEMLRAFDDLGVDVIITEAFEEKDLGVAIMNRLKKSCGFDITIV
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEC
>Mature Secondary Structure
MKTKVQFIKDIDKDIKYLEEAAEIIKNGGIGAFPTETVYGLGANALDGEAVKKIFVAKGR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCC
PQDNPLIIHIADKKDIDKYVAEIPKYAQELMDKFWPGPLTIILKKKDIVSDVTSAGLDTV
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCE
GVRMPNDEIALKLIELSGVPIAAPSANISGRPSPTDIERCEEDLNGRVDFIIGAKKSEIG
EEECCCHHHEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCC
VESTIVDATGEHLCVLRPGGITLEMLKDIDEGVDIDKAILTTLDKDTKPKAPGMKYKHYA
CHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PKAKVRMVQGPINKMVEKIKEIVHNYIDEDLKVGIMATDETISMYDEGIVKSLGTREDLT
CCHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHH
SVTKNLFEMLRAFDDLGVDVIITEAFEEKDLGVAIMNRLKKSCGFDITIV
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]