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The map label for this gene is nfuA

Identifier: 182682596

GI number: 182682596

Start: 2343347

End: 2343946

Strand: Reverse

Name: nfuA

Synonym: XfasM23_2084

Alternate gene names: 182682596

Gene position: 2343946-2343347 (Counterclockwise)

Preceding gene: 182682599

Following gene: 182682595

Centisome position: 92.44

GC content: 52.33

Gene sequence:

>600_bases
ATGATCCAGATTTCTGACACAGCTAAGTCTCACTTCCTTAAATTGATCCAACGCGAAGGTGTCCCTGGGATGGGGGTACG
TTTGAGTGCGGTGGATCCCGGCACACCGCGTGCCGACGCGCGCTTGGAGTTTGCCGATCCCTCGGAATTGGTTGGCGATG
AATGGTTGATAGATTGTGGTGACTTCACCCTCTATGTCGCTTCAGCCAGCGTGGCATGGCTGGATGGTGCTGAGATCGAC
TACGTTACACAGGCCACTGGTAGTCAGCAATTGATCATCAAAGCTCCGAAGATTAAAGGTCAGGAGCTTAGTCAGGTTGC
ATCATTGGTTGAGAGAGTGTGTTGGGTTGTGGAGAACGAGATTAACCCGCAATTAGCATCCCATGGTGGACGAGTGGAGG
TACAGGAGGTTTCTGCAGAAGGAGTTGTCTTACTGCGTTTTGGCGGTGGCTGCCACGGCTGTGGCATGGCTGATGTAACT
CTTAAGCAGGGCGTTGAGAAAACCCTGATGGACCGAGTACATGGTGTGATTGCAGTACGTGATGCGACCGACCACAGTAC
AGGTGCGGCTCCATATATTTCTCGCGATTTTTCCCCCTGA

Upstream 100 bases:

>100_bases
GCTAGAGTAATCCGATCGTTCATTGAGCATCCTGGTGTCATTAGTATGTGCATACTAGGGTGAGGCGAATGCGATACTAA
GTGAATTTAGAATAACCAAC

Downstream 100 bases:

>100_bases
TTTTTTCTTTGCGATGACACACGCTCAATTCACGCATTTTTTATCTTGATGCACACTTATTTTCCGGACTTGTTAATCCT
CAGGTCGATTAGTCGCTTGC

Product: HesB/YadR/YfhF-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCGDFTLYVASASVAWLDGAEID
YVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGVEKTLMDRVHGVIAVRDATDHSTGAAPYISRDFSP

Sequences:

>Translated_199_residues
MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCGDFTLYVASASVAWLDGAEID
YVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGVEKTLMDRVHGVIAVRDATDHSTGAAPYISRDFSP
>Mature_199_residues
MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCGDFTLYVASASVAWLDGAEID
YVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGVEKTLMDRVHGVIAVRDATDHSTGAAPYISRDFSP

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=192, Percent_Identity=41.6666666666667, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_XYLF2 (B2I9W5)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830756.1
- ProteinModelPortal:   B2I9W5
- GeneID:   6203459
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_2084
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- ProtClustDB:   CLSK446553
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- ProDom:   PD002830

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21317; Mature: 21317

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCG
CEEECCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHCCCCEEEECC
DFTLYVASASVAWLDGAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENE
CEEEEEEECEEEEECCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
INPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGVEKTLMDRVHGVIAVR
CCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
DATDHSTGAAPYISRDFSP
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCG
CEEECCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHCCCCEEEECC
DFTLYVASASVAWLDGAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENE
CEEEEEEECEEEEECCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
INPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGVEKTLMDRVHGVIAVR
CCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEE
DATDHSTGAAPYISRDFSP
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA